chr22:23,537,973–23,538,579

chr22 : 23,537,973 – 23,538,579

606 bp 90 TFs 5 linked genes

This 606 bp open chromatin element is linked to 5 target genes and is bound by 90 transcription factors.

Linked Genes

5 genes

Gene	Expression	Dist. to TSS	Distance	Link type
PCAT14		1.1 kb	Proximal	Proximity
ENSG00000291299		155.0 kb	Distal	Multiome
CHCHD10		229.8 kb	Distal	Multiome
MMP11		234.7 kb	Distal	Multiome
SMARCB1		248.8 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

90 transcription factors

ARID1B 1 dataset

ChIP K562 ENCFF938UXQ 263 bp overlap

ARID5B 1 dataset

ChIP HepG2 ENCFF964FWK 120 bp overlap

ChIP K562 ENCFF308SKS 544 bp overlap

BAZ2A 1 dataset

ChIP HepG2 ENCFF797RVO 544 bp overlap

BRD4 6 datasets

ChIP BE2C GSE80151.BRD4.BE2C 55 bp overlap

ChIP KOPT-K1 GSE54379.BRD4.KOPT-K1 305 bp overlap

ChIP KOPT-K1_E GSE54379.BRD4.KOPT-K1_E 309 bp overlap

ChIP MOLT-4_DMSO GSE79288.BRD4.MOLT-4_DMSO 136 bp overlap

ChIP SK-N-BE2-C GSE80151.BRD4.SK-N-BE2-C 55 bp overlap

ChIP SK-N-BE2-C_Resistant-veh GSE107706.BRD4.SK-N-BE2-C_Resistant-veh 120 bp overlap

CBFA2T2 1 dataset

ChIP K562 ENCFF963TXY 381 bp overlap

CBFA2T3 1 dataset

ChIP K562 ENCFF673OEZ 341 bp overlap

CTBP1 1 dataset

ChIP K562 ENCFF403WPG 518 bp overlap

CTCF 39 datasets

ChIP AG04449 ENCFF248MBD 181 bp overlap

ChIP Caco-2 ENCFF934QYS 217 bp overlap

ChIP H9 ENCFF152GTF 461 bp overlap

ChIP HepG2 ENCFF757EKU 351 bp overlap

ChIP HepG2 ENCFF757EKU 205 bp overlap

ChIP K-562 ENCSR000DMA.CTCF.K-562 123 bp overlap

ChIP K-562_MonoC GSE137216.CTCF.K-562_MonoC 248 bp overlap

ChIP K562 ENCFF082GOI 185 bp overlap

ChIP K562 ENCFF400DFR 241 bp overlap

ChIP adrenal gland ENCFF678WUB 311 bp overlap

ChIP brain ENCFF067KUH 443 bp overlap

ChIP brain ENCFF067KUH 505 bp overlap

ChIP brain ENCFF685VRG 534 bp overlap

ChIP brain microvascular endothelial cell ENCFF526VHE 281 bp overlap

ChIP cardiac muscle cell ENCFF728JSA 365 bp overlap

ChIP cardiac muscle cell ENCFF728JSA 235 bp overlap

ChIP choroid plexus epithelial cell ENCFF407YNR 277 bp overlap

ChIP choroid-plexus_epithelial ENCSR000DTL.CTCF.choroid-plexus_epithelial 114 bp overlap

ChIP endodermal cell ENCFF471YCZ 153 bp overlap

ChIP fibroblast of pulmonary artery ENCFF742RSV 297 bp overlap

ChIP fibroblast_PULMONARY_ARTERY ENCSR000DUX.CTCF.fibroblast_PULMONARY_ARTERY 127 bp overlap

ChIP gastroesophageal sphincter ENCFF918KPI 337 bp overlap

ChIP hepatocyte ENCFF263BLJ 114 bp overlap

ChIP mesothelial cell of epicardium ENCFF427RFE 544 bp overlap

ChIP mesothelial cell of epicardium ENCFF427RFE 344 bp overlap

ChIP nephron ENCFF411ACD 491 bp overlap

ChIP nephron ENCFF589HXU 521 bp overlap

ChIP nephron ENCFF972IQB 465 bp overlap

ChIP neural cell ENCFF335ADI 485 bp overlap

ChIP ovary ENCFF062XMG 424 bp overlap

ChIP ovary ENCFF845YUT 381 bp overlap

ChIP progenitor cell of endocrine pancreas ENCFF492KHV 437 bp overlap

ChIP prostate gland ENCFF655GBO 341 bp overlap

ChIP retinal pigment epithelial cell ENCFF810AAG 257 bp overlap

ChIP testis ENCFF128XQJ 371 bp overlap

ChIP testis ENCFF409BGH 291 bp overlap

ChIP testis ENCFF919VBQ 381 bp overlap

ChIP testis ENCFF919VBQ 175 bp overlap

ChIP type B pancreatic cell ENCFF910FNQ 491 bp overlap

CXXC5 1 dataset

ChIP K562 ENCFF497CZN 491 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF274GAT 251 bp overlap

ESRRA 1 dataset

ChIP K562 ENCFF968PEP 228 bp overlap

ETV5 2 datasets

ChIP HepG2 ENCFF456LSA 115 bp overlap

ChIP K562 ENCFF336FFA 484 bp overlap

FOXA1 1 dataset

ChIP HepG2 ENCFF207NVJ 100 bp overlap

FOXA2 3 datasets

ChIP DE DE-FOXA2-1 365 bp overlap

ChIP DE DE-FOXA2-2 213 bp overlap

ChIP HepG2 ENCFF894AYY 100 bp overlap

FOXA3 1 dataset

ChIP HepG2 ENCFF005KGL 126 bp overlap

GATA2 2 datasets

ChIP K562 ENCFF088XQT 401 bp overlap

ChIP K562 ENCFF830LLA 524 bp overlap

GATA4 5 datasets

ChIP DE DE-GATA4-1 568 bp overlap

ChIP DE DE-GATA4-2 606 bp overlap

ChIP foregut GSE117136.GATA4.foregut 259 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 241 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 296 bp overlap

GATA6 9 datasets

ChIP DE DE-GATA6-1 578 bp overlap

ChIP DE DE-GATA6-2 606 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 455 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 603 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 606 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 606 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 263 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 321 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 412 bp overlap

GFI1 2 datasets

ChIP HepG2 ENCFF472INF 425 bp overlap

ChIP HepG2 ENCFF472INF 225 bp overlap

HDAC2 1 dataset

ChIP Hep-G2 ENCSR000BMC.HDAC2.Hep-G2 160 bp overlap

HNF1A 1 dataset

ChIP HepG2 ENCFF540TRC 515 bp overlap

HOXA3 1 dataset

ChIP Hep-G2 ENCSR999JKC.HOXA3.Hep-G2 117 bp overlap

IKZF1 2 datasets

ChIP K562 ENCFF348IBL 381 bp overlap

ChIP K562 ENCFF771OHZ 319 bp overlap

KDM1A 2 datasets

ChIP K562 ENCFF128TYE 461 bp overlap

ChIP K562 ENCFF934ZRG 501 bp overlap

KDM5B 3 datasets

ChIP HepG2 ENCFF706LUI 604 bp overlap

ChIP K562 ENCFF049WWX 414 bp overlap

ChIP K562 ENCFF049WWX 606 bp overlap

KMT2A 1 dataset

ChIP RCH-ACV GSE83671.KMT2A.RCH-ACV 320 bp overlap

L3MBTL2 1 dataset

ChIP K562 ENCFF320EQC 151 bp overlap

ChIP K562 ENCFF198WCP 457 bp overlap

ChIP HepG2 ENCFF507HCX 249 bp overlap

ChIP K562 ENCFF398VJM 329 bp overlap

ChIP HepG2 ENCFF495TSS 318 bp overlap

ChIP K562 ENCFF140CEX 354 bp overlap

ChIP K562 ENCFF140CEX 572 bp overlap

ChIP HepG2 ENCFF652PXN 325 bp overlap

ChIP HepG2 ENCFF938KYA 425 bp overlap

ChIP K562 ENCFF230ZKA 445 bp overlap

ChIP K562 ENCFF289UFB 469 bp overlap

MYBL2 1 dataset

ChIP Hep-G2 ENCSR581KCO.MYBL2.Hep-G2 71 bp overlap

NCOA2 1 dataset

ChIP HepG2 ENCFF853BJJ 110 bp overlap

NCOR1 2 datasets

ChIP K562 ENCFF788MPU 421 bp overlap

ChIP K562 ENCFF866HRM 445 bp overlap

NR2F2 2 datasets

ChIP liver ENCFF565JGD 213 bp overlap

ChIP liver ENCSR168SMX.NR2F2.liver 146 bp overlap

NR2F6 5 datasets

ChIP Hep-G2 ENCSR518WPL.NR2F6.Hep-G2 145 bp overlap

ChIP HepG2 ENCFF429VKC 318 bp overlap

ChIP HepG2 ENCFF429VKC 109 bp overlap

ChIP HepG2 ENCFF514UJI 114 bp overlap

ChIP HepG2 ENCFF514UJI 303 bp overlap

NR3C1 2 datasets

ChIP A-549 ENCSR000BHF.NR3C1.A-549 169 bp overlap

ChIP U2OS_GLUCC ERP007081.NR3C1.U2OS_GLUCC 57 bp overlap

NUTM1 1 dataset

ChIP embryonic-kidney_induced GSE133122.NUTM1.embryonic-kidney_induced 327 bp overlap

PAXIP1 3 datasets

ChIP HepG2 ENCFF526NOJ 144 bp overlap

ChIP HepG2 ENCFF526NOJ 428 bp overlap

ChIP HepG2 ENCFF526NOJ 437 bp overlap

PHF21A 1 dataset

ChIP K562 ENCFF088QME 321 bp overlap

POGZ 2 datasets

ChIP HepG2 ENCFF153UUK 457 bp overlap

ChIP HepG2 ENCFF153UUK 460 bp overlap

PPARG 2 datasets

ChIP Hep-G2 ENCSR130VQL.PPARG.Hep-G2 177 bp overlap

ChIP HepG2 ENCFF329FBJ 201 bp overlap

PRDM10 1 dataset

ChIP K562 ENCFF740YLK 417 bp overlap

PROX1 1 dataset

ChIP HepG2 ENCFF016ZJS 202 bp overlap

RAD21 3 datasets

ChIP HEK293_siE1A GSE130135.RAD21.HEK293_siE1A 127 bp overlap

ChIP K562 ENCFF066JWO 405 bp overlap

ChIP K562 ENCFF634XYR 178 bp overlap

ChIP HepG2 ENCFF582XUA 269 bp overlap

RBBP5 2 datasets

ChIP K562 ENCFF070CVK 423 bp overlap

ChIP K562 ENCFF070CVK 606 bp overlap

ChIP K562 ENCFF688UKW 411 bp overlap

ChIP K562 ENCFF653BQJ 504 bp overlap

RXRA 2 datasets

ChIP Hep-G2 ENCSR000BHU.RXRA.Hep-G2 176 bp overlap

ChIP HepG2 ENCFF204YVO 278 bp overlap

ChIP HepG2 ENCFF539ZAY 208 bp overlap

SAP130 1 dataset

ChIP HepG2 ENCFF892EHZ 194 bp overlap

ChIP HepG2 ENCFF631IPX 353 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 223 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 302 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 606 bp overlap

SMAD4 1 dataset

ChIP HepG2 ENCFF615GTE 198 bp overlap

SMARCA4 1 dataset

ChIP K562 ENCFF506JCB 485 bp overlap

SMARCC1 1 dataset

ChIP HS-SY-2 GSE108025.SMARCC1.HS-SY-2 178 bp overlap

SMARCE1 1 dataset

ChIP K562 ENCFF690CFF 475 bp overlap

SOX13 2 datasets

ChIP HepG2 ENCFF062VSQ 135 bp overlap

ChIP HepG2 ENCFF062VSQ 199 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 446 bp overlap

ChIP HepG2 ENCFF470KZD 132 bp overlap

ChIP HepG2 ENCFF767OCK 378 bp overlap

ChIP HepG2 ENCFF123KAM 119 bp overlap

ChIP HepG2 ENCFF123KAM 212 bp overlap

SPI1 2 datasets

ChIP K-562 ENCSR000BGW.SPI1.K-562 136 bp overlap

ChIP K562 ENCFF410ORC 54 bp overlap

ChIP K562 ENCFF620GMX 385 bp overlap

TCF12 1 dataset

ChIP K562 ENCFF931DJY 391 bp overlap

TCF3 2 datasets

ChIP K562 ENCFF319QZT 158 bp overlap

ChIP Kasumi-1 GSE43834.TCF3.Kasumi-1 314 bp overlap

TFDP1 2 datasets

ChIP K562 ENCFF794ZXJ 243 bp overlap

ChIP K562 ENCFF794ZXJ 475 bp overlap

TWIST1 2 datasets

ChIP BE2C GSE80151.TWIST1.BE2C 262 bp overlap

ChIP SK-N-BE2-C GSE80151.TWIST1.SK-N-BE2-C 262 bp overlap

ZBTB33 1 dataset

ChIP HepG2 ENCFF778UKV 159 bp overlap

ZBTB38 1 dataset

ChIP HepG2 ENCFF875UQX 200 bp overlap

ZBTB42 2 datasets

ChIP HepG2 ENCFF153JWK 440 bp overlap

ChIP HepG2 ENCFF153JWK 238 bp overlap

ZFHX3 3 datasets

ChIP HepG2 ENCFF082SJV 138 bp overlap

ChIP HepG2 ENCFF082SJV 471 bp overlap

ChIP HepG2 ENCFF082SJV 352 bp overlap

ZFP3 2 datasets

ChIP SK-N-SH ENCFF981MBE 291 bp overlap

ChIP SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour ENCSR581GUY.ZFP3.SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour 155 bp overlap

ZFP91 1 dataset

ChIP HepG2 ENCFF012CME 606 bp overlap

ChIP K562 ENCFF169LZT 558 bp overlap

ChIP K562 ENCFF536AJO 606 bp overlap

ZMYM3 2 datasets

ChIP HepG2 ENCFF408KTI 343 bp overlap

ChIP HepG2 ENCFF408KTI 380 bp overlap

ZNF263 1 dataset

ChIP K562 ENCFF640RNA 521 bp overlap

ZNF281 1 dataset

ChIP K562 ENCFF594VNM 422 bp overlap

ZNF317 1 dataset

ChIP HepG2 ENCFF018ISP 142 bp overlap

ZNF430 1 dataset

ChIP HepG2 ENCFF967HQR 252 bp overlap

ZNF462 1 dataset

ChIP GM23338 ENCFF896CCA 251 bp overlap

ZNF687 1 dataset

ChIP HepG2 ENCFF653WIX 316 bp overlap

ZNF710 2 datasets

ChIP HepG2 ENCFF170JWO 459 bp overlap

ChIP HepG2 ENCFF170JWO 258 bp overlap