Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for ZNF710. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = ZNF710 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of ZNF710, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr15:89,747,326–89,748,774 | 253.3 kb | Distal (>10kb) Multiome | 214 | |
| chr15:89,750,169–89,751,978 | 250.4 kb | Distal (>10kb) Multiome | 732 | |
| chr15:89,760,201–89,761,182 | 240.6 kb | Distal (>10kb) Multiome | 473 | |
| chr15:89,775,879–89,777,425 | 224.7 kb | Distal (>10kb) Multiome | 647 | |
| chr15:89,893,669–89,894,442 | 107.3 kb | Distal (>10kb) Multiome | 1083 | |
| chr15:89,912,261–89,913,121 | 88.5 kb | Distal (>10kb) Multiome | 514 | |
| chr15:89,999,673–90,000,089 | 1.4 kb | Proximal (<10kb) Multiome | 174 | |
| chr15:90,000,139–90,000,866 | 456 bp | At TSS | 271 | |
| chr15:90,001,237–90,002,666 | 442 bp | At TSS Multiome | 589 | |
| chr15:90,059,488–90,060,208 | 58.5 kb | Distal (>10kb) Multiome HiCAR | 439 | |
| chr15:90,061,829–90,062,285 | 60.8 kb | Distal (>10kb) Multiome HiCAR | 347 | |
| chr15:90,075,459–90,076,479 | 74.6 kb | Distal (>10kb) Multiome | 275 | |
| chr15:90,101,730–90,103,001 | 101.2 kb | Distal (>10kb) Multiome | 693 | |
| chr15:90,143,210–90,143,683 | 142.1 kb | Distal (>10kb) Multiome | 578 | |
| chr15:90,152,072–90,152,533 | 151.0 kb | Distal (>10kb) Multiome | 92 | |
| chr15:90,157,949–90,158,473 | 156.9 kb | Distal (>10kb) Multiome | 670 | |
| chr15:90,184,585–90,185,456 | 183.7 kb | Distal (>10kb) Multiome | 806 | |
| chr15:90,200,589–90,202,277 | 200.0 kb | Distal (>10kb) Multiome | 649 | |
| chr15:90,233,136–90,234,524 | 232.7 kb | Distal (>10kb) Multiome | 900 | |
| chr15:90,249,345–90,249,851 | 248.2 kb | Distal (>10kb) Multiome | 655 | |
| chr15:90,265,146–90,266,455 | 264.3 kb | Distal (>10kb) Multiome | 956 | |
| chr15:90,293,225–90,293,932 | 292.2 kb | Distal (>10kb) Multiome | 251 | |
| chr15:90,301,063–90,301,545 | 300.0 kb | Distal (>10kb) Multiome | 241 |
Genomic view of the ZNF710 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.