chr21 : 32,432,983 – 32,433,635
652 bp 99 TFs 5 linked genes
This 652 bp open chromatin element is linked to 5 target genes and is bound by 99 transcription factors.
Linked Genes
5 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
URB1 40.3 kb Distal Multiome
MIS18A 154.3 kb Distal Multiome
CFAP298 179.3 kb Distal Multiome
SYNJ1 294.6 kb Distal Multiome
PAXBP1-AS1 294.8 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr21:32,427,983 – 32,438,635
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
99 transcription factors
Source
Cell type
ARID3A 2 datasets
ChIP Hep-G2 ENCSR000EDP.ARID3A.Hep-G2 138 bp overlap
ChIP HepG2 ENCFF341DES 380 bp overlap
ARID5B 1 dataset
ChIP HepG2 ENCFF964FWK 154 bp overlap
ASH2L 2 datasets
ChIP Hep-G2 ENCSR508LMH.ASH2L.Hep-G2 394 bp overlap
ChIP HepG2 ENCFF207QHL 625 bp overlap
BCL6 1 dataset
ChIP HepG2 ENCFF423EJH 377 bp overlap
Bcl11B 1 dataset
Motif DE_72h DE_72h-Bcl11B_MA1989.2 9 bp overlap
CBFB 1 dataset
ChIP HepG2 ENCFF349HFU 110 bp overlap
CREM 1 dataset
ChIP HepG2 ENCFF049UDY 426 bp overlap
CTCF 1 dataset
ChIP bonchial_epithelial ENCSR000DXI.CTCF.bonchial_epithelial 115 bp overlap
ELF3 3 datasets
ChIP PDAC GSE64557.ELF3.PDAC 330 bp overlap
ChIP PDAC_KOKLF5 GSE64557.ELF3.PDAC_KOKLF5 305 bp overlap
ChIP PDAC_SHCTR GSE64557.ELF3.PDAC_SHCTR 329 bp overlap
EOMES 2 datasets
ChIP hESC GSE26097.EOMES.hESC 180 bp overlap
ChIP hESC GSE26097.EOMES.hESC 180 bp overlap
EP300 5 datasets
ChIP A-549 ENCSR000BPW.EP300.A-549 351 bp overlap
ChIP A549 ENCFF960ZEI 448 bp overlap
ChIP Hep-G2 ENCSR000BLW.EP300.Hep-G2 487 bp overlap
ChIP HepG2 ENCFF076TMZ 365 bp overlap
ChIP HepG2 ENCFF354ACD 325 bp overlap
EWSR1-FLI1 1 dataset
Motif DE_72h DE_72h-EWSR1-FLI1_MA0149.1 18 bp overlap
FOS 1 dataset
ChIP CFPAC-1 GSE119930.FOS.CFPAC-1 325 bp overlap
FOSL1 1 dataset
ChIP HepG2 ENCFF095FBN 331 bp overlap
FOSL2 2 datasets
ChIP Hep-G2 ENCSR000BHP.FOSL2.Hep-G2 188 bp overlap
ChIP HepG2 ENCFF548CXY 294 bp overlap
FOXA1 12 datasets
ChIP A-549 ENCSR000BPX.FOXA1.A-549 252 bp overlap
ChIP A-549 ENCSR000BRD.FOXA1.A-549 181 bp overlap
ChIP CFPAC-1 GSE119930.FOXA1.CFPAC-1 652 bp overlap
ChIP CFPAC-1_FOXA1-KO GSE119930.FOXA1.CFPAC-1_FOXA1-KO 652 bp overlap
ChIP CFPAC-1_FOXA2-KO GSE119930.FOXA1.CFPAC-1_FOXA2-KO 652 bp overlap
ChIP HepG2 ENCFF207NVJ 81 bp overlap
ChIP HepG2 ENCFF361KNY 285 bp overlap
ChIP HepG2 ENCFF740VZW 93 bp overlap
ChIP LS180 GSE140533.FOXA1.LS180 207 bp overlap
ChIP PDAC GSE64557.FOXA1.PDAC 652 bp overlap
ChIP PDAC_KOKLF5 GSE64557.FOXA1.PDAC_KOKLF5 652 bp overlap
ChIP PDAC_SHCTR GSE64557.FOXA1.PDAC_SHCTR 600 bp overlap
FOXA2 8 datasets
ChIP CFPAC-1 GSE119930.FOXA2.CFPAC-1 604 bp overlap
ChIP CFPAC-1_EV GSE119930.FOXA2.CFPAC-1_EV 652 bp overlap
ChIP CFPAC-1_HNF1B-KO GSE119930.FOXA2.CFPAC-1_HNF1B-KO 497 bp overlap
ChIP CFPAC-1_HOXB8-OE GSE119930.FOXA2.CFPAC-1_HOXB8-OE 475 bp overlap
ChIP DE DE-FOXA2-1 652 bp overlap
ChIP DE DE-FOXA2-2 652 bp overlap
ChIP HepG2 ENCFF570ABM 403 bp overlap
ChIP HepG2 ENCFF894AYY 381 bp overlap
FOXA3 1 dataset
ChIP HepG2 ENCFF005KGL 361 bp overlap
FOXP1 1 dataset
ChIP HepG2 ENCFF823ERM 341 bp overlap
FOXQ1 1 dataset
ChIP HepG2 ENCFF164USD 501 bp overlap
GATA1 3 datasets
ChIP CD34_Day7_30min GSE104676.GATA1.CD34_Day7_30min 102 bp overlap
ChIP erythroblast ENCFF867JAR 491 bp overlap
ChIP erythroblast ENCSR000EXP.GATA1.erythroblast 341 bp overlap
GATA2 1 dataset
ChIP HepG2 ENCFF905PYM 349 bp overlap
GATA3 2 datasets
ChIP A-549 ENCSR000BTI.GATA3.A-549 185 bp overlap
ChIP A549 ENCFF226FVV 395 bp overlap
GATA4 7 datasets
ChIP DE DE-GATA4-1 652 bp overlap
ChIP DE DE-GATA4-2 652 bp overlap
ChIP Hep-G2 ENCSR590CNM.GATA4.Hep-G2 134 bp overlap
ChIP HepG2 ENCFF309FOQ 397 bp overlap
ChIP foregut GSE117136.GATA4.foregut 433 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 411 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 384 bp overlap
GATA5 1 dataset
Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap
GATA6 18 datasets
ChIP AGS GSE51705.GATA6.AGS 184 bp overlap
ChIP AGS GSE51705.GATA6.AGS 236 bp overlap
ChIP DE DE-GATA6-1 652 bp overlap
ChIP DE DE-GATA6-2 652 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 652 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 652 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 652 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 652 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 652 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 652 bp overlap
ChIP PATU8988 GSE47535.GATA6.PATU8988 249 bp overlap
ChIP YCC-3 GSE51705.GATA6.YCC-3 212 bp overlap
ChIP YCC-3 GSE51705.GATA6.YCC-3 250 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 391 bp overlap
ChIP foregut GSE117136.GATA6.foregut 520 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 264 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 282 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 379 bp overlap
GATAD2A 1 dataset
ChIP HepG2 ENCFF252XNH 459 bp overlap
HMG20A 1 dataset
ChIP HepG2 ENCFF599VWU 152 bp overlap
HNF1A 2 datasets
ChIP HepG2 ENCFF352VYI 411 bp overlap
ChIP HepG2 ENCFF540TRC 493 bp overlap
HNF1B 1 dataset
ChIP PDAC GSE64557.HNF1B.PDAC 551 bp overlap
HNF4A 2 datasets
Motif DE_72h DE_72h-HNF4A_MA0114.5 9 bp overlap
ChIP IM95 GSE114018.HNF4A.IM95 228 bp overlap
HNF4G 1 dataset
Motif DE_72h DE_72h-HNF4G_MA0484.3 9 bp overlap
IRF1 1 dataset
ChIP PDAC GSE64557.IRF1.PDAC 485 bp overlap
JUN 2 datasets
ChIP A549 ENCFF846DUV 172 bp overlap
ChIP DE_D1 S40-DE-d1-JUN-exp2 638 bp overlap
JUNB 1 dataset
ChIP CFPAC-1 GSE119930.JUNB.CFPAC-1 349 bp overlap
JUND 2 datasets
ChIP Hep-G2 ENCSR000BGK.JUND.Hep-G2 102 bp overlap
ChIP HepG2 ENCFF172HFZ 251 bp overlap
KDM6A 1 dataset
ChIP HepG2 ENCFF135ECT 381 bp overlap
KLF4 1 dataset
ChIP PDAC GSE64557.KLF4.PDAC 652 bp overlap
KLF6 1 dataset
ChIP PDAC GSE64557.KLF6.PDAC 600 bp overlap
KMT2B-D 1 dataset
ChIP SW480 GSE115985.KMT2B-D.SW480 234 bp overlap
L3MBTL2 1 dataset
ChIP K562 ENCFF320EQC 518 bp overlap
MAX 2 datasets
ChIP HepG2 ENCFF507HCX 529 bp overlap
ChIP HepG2 ENCFF507HCX 538 bp overlap
MED26 1 dataset
ChIP HCT-116_aux GSE121355.MED26.HCT-116_aux 261 bp overlap
MYC 1 dataset
ChIP GP5D GSE51234.MYC.GP5D 307 bp overlap
NCOA2 1 dataset
ChIP HepG2 ENCFF853BJJ 416 bp overlap
NFIC::TLX1 1 dataset
Motif DE_72h DE_72h-NFICTLX1_MA0119.1 14 bp overlap
NIPBL 2 datasets
ChIP GP5D GSE51234.NIPBL.GP5D 388 bp overlap
ChIP HCT-116_RAD21-mAC_500uM_auxin GSE104888.NIPBL.HCT-116_RAD21-mAC_500uM_auxin 373 bp overlap
NR2F1 1 dataset
ChIP HepG2 ENCFF518ZRY 136 bp overlap
NR2F2 2 datasets
ChIP Hep-G2 ENCSR000BVM.NR2F2.Hep-G2 158 bp overlap
ChIP HepG2 ENCFF483TVJ 401 bp overlap
NR2F6 2 datasets
ChIP HepG2 ENCFF429VKC 441 bp overlap
ChIP HepG2 ENCFF514UJI 345 bp overlap
NR3C1 1 dataset
ChIP A-549 ENCSR000BHF.NR3C1.A-549 233 bp overlap
PDX1 2 datasets
ChIP hiPSC GSE125768.PDX1.hiPSC 185 bp overlap
ChIP hiPSC_derived_PPs GSE106949.PDX1.hiPSC_derived_PPs 206 bp overlap
POLR2A 5 datasets
ChIP body of pancreas ENCFF675RCN 499 bp overlap
ChIP body of pancreas ENCFF675RCN 277 bp overlap
ChIP prostate gland ENCFF832RQK 357 bp overlap
ChIP prostate gland ENCFF881OMH 392 bp overlap
ChIP upper lobe of left lung ENCFF640VPA 495 bp overlap
PROX1 2 datasets
ChIP SW480 GSE60390.PROX1.SW480 110 bp overlap
ChIP SW480 GSE60390.PROX1.SW480 252 bp overlap
Prdm15 1 dataset
Motif DE_72h DE_72h-Prdm15_MA1616.2 11 bp overlap
RARA 2 datasets
ChIP HepG2 ENCFF582XUA 227 bp overlap
ChIP HepG2 ENCFF582XUA 357 bp overlap
RELA 1 dataset
ChIP SW480_16h_TNFa GSE102796.RELA.SW480_16h_TNFa 202 bp overlap
RERE 1 dataset
ChIP HepG2 ENCFF145QRA 381 bp overlap
RFX1 1 dataset
ChIP MCF-7 ENCFF782EZS 299 bp overlap
RXRA 1 dataset
ChIP HepG2 ENCFF763IEA 496 bp overlap
Runx1 1 dataset
Motif DE_72h DE_72h-Runx1_MA0002.3 9 bp overlap
SALL1 1 dataset
ChIP HepG2 ENCFF426MCK 497 bp overlap
SAP130 2 datasets
ChIP HepG2 ENCFF892EHZ 507 bp overlap
ChIP HepG2 ENCFF892EHZ 475 bp overlap
SMAD2_3 4 datasets
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 253 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 318 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 243 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 507 bp overlap
SMAD3 2 datasets
ChIP HCC1954 GSE104760.SMAD3.HCC1954 464 bp overlap
ChIP HCC1954_TGFb GSE104760.SMAD3.HCC1954_TGFb 303 bp overlap
SMAD4 1 dataset
ChIP HepG2 ENCFF615GTE 337 bp overlap
SMARCA4 8 datasets
ChIP A-549_AG15677 GSE132290.SMARCA4.A-549_AG15677 252 bp overlap
ChIP A-549_AG15679 GSE132290.SMARCA4.A-549_AG15679 201 bp overlap
ChIP A-549_AG15720 GSE132290.SMARCA4.A-549_AG15720 150 bp overlap
ChIP A-549_AG15721 GSE132290.SMARCA4.A-549_AG15721 92 bp overlap
ChIP A-549_AG15722 GSE132290.SMARCA4.A-549_AG15722 53 bp overlap
ChIP A-549_AG15722 GSE132290.SMARCA4.A-549_AG15722 53 bp overlap
ChIP A-549_AG15723 GSE132290.SMARCA4.A-549_AG15723 261 bp overlap
ChIP A-549_AG15725 GSE132290.SMARCA4.A-549_AG15725 74 bp overlap
SOX13 1 dataset
ChIP HepG2 ENCFF062VSQ 357 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 596 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 564 bp overlap
SOX2 1 dataset
ChIP LK2_GFP GSE137459.SOX2.LK2_GFP 180 bp overlap
SOX5 1 dataset
ChIP HepG2 ENCFF470KZD 390 bp overlap
SP1 1 dataset
ChIP A-549 ENCSR000BPE.SP1.A-549 189 bp overlap
STAT1 1 dataset
Motif DE_72h DE_72h-STAT1_MA0137.4 9 bp overlap
STAT3 4 datasets
Motif DE_72h DE_72h-STAT3_MA0144.3 9 bp overlap
ChIP HCC70_EtOH GSE85579.STAT3.HCC70_EtOH 176 bp overlap
ChIP MDA-MB-231_EtOH GSE85579.STAT3.MDA-MB-231_EtOH 171 bp overlap
ChIP MDA-MB-468_EtOH GSE85579.STAT3.MDA-MB-468_EtOH 164 bp overlap
Sox11 1 dataset
Motif DE_72h DE_72h-Sox11_MA0869.3 8 bp overlap
Stat4 1 dataset
Motif DE_72h DE_72h-Stat4_MA0518.2 10 bp overlap
Stat5a::Stat5b 1 dataset
Motif DE_72h DE_72h-Stat5aStat5b_MA0519.2 9 bp overlap
Stat5b 1 dataset
Motif DE_72h DE_72h-Stat5b_MA1625.2 9 bp overlap
TBX2 1 dataset
ChIP HepG2 ENCFF811TLA 568 bp overlap
TBX3 2 datasets
ChIP HepG2 ENCFF045YCM 341 bp overlap
ChIP HepG2 ENCFF178RIL 201 bp overlap
TCF12 1 dataset
ChIP A-549 ENCSR000BQQ.TCF12.A-549 215 bp overlap
TCF7 2 datasets
ChIP Hep-G2 ENCSR444LIN.TCF7.Hep-G2 471 bp overlap
ChIP HepG2 ENCFF628OFQ 230 bp overlap
TCF7L2 3 datasets
Motif DE_72h DE_72h-TCF7L2_MA0523.2 9 bp overlap
ChIP HepG2 ENCFF510OLG 442 bp overlap
ChIP LNCaP GSE51621.TCF7L2.LNCaP 242 bp overlap
TEAD1 2 datasets
ChIP HUCCT1 GSE68296.TEAD1.HUCCT1 176 bp overlap
ChIP HepG2 ENCFF661PNM 377 bp overlap
TFAP4 1 dataset
ChIP DLD-1 GSE46935.TFAP4.DLD-1 287 bp overlap
TFE3 1 dataset
ChIP HepG2 ENCFF268PFH 174 bp overlap
USF1 3 datasets
ChIP Hep-G2 ENCSR000BGM.USF1.Hep-G2 99 bp overlap
ChIP HepG2 ENCFF201JKA 156 bp overlap
ChIP HepG2 ENCFF807KYJ 201 bp overlap
USF2 1 dataset
ChIP K562 ENCFF397QGU 265 bp overlap
XRCC5 2 datasets
ChIP K-562 ENCSR506KWJ.XRCC5.K-562 161 bp overlap
ChIP K-562 GSE120104.XRCC5.K-562 183 bp overlap
YY1AP1 1 dataset
ChIP PC-9_1DF GSE131687.YY1AP1.PC-9_1DF 356 bp overlap
ZEB1 1 dataset
ChIP HepG2 ENCFF808RQT 420 bp overlap
ZFHX3 1 dataset
ChIP HepG2 ENCFF082SJV 380 bp overlap
ZFY 1 dataset
ChIP HepG2 ENCFF106ELT 567 bp overlap
ZNF143 1 dataset
ChIP FLP143HA_T0 GSE39263.ZNF143.FLP143HA_T0 149 bp overlap
ZNF264 1 dataset
ChIP HepG2 ENCFF453WJV 450 bp overlap
ZNF503 1 dataset
ChIP HepG2 ENCFF923HZL 499 bp overlap
ZNF770 1 dataset
ChIP HepG2 ENCFF233UVH 74 bp overlap
Zfp335 1 dataset
Motif DE_72h DE_72h-Zfp335_MA2002.2 7 bp overlap
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