chr18 : 25,349,158 – 25,349,342
184 bp 82 TFs 1 linked gene
This 184 bp open chromatin element is linked to ZNF521 and is bound by 82 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ZNF521 1.9 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr18:25,344,158 – 25,354,342
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
82 transcription factors
Source
Cell type
ARID2 1 dataset
ChIP Aska-SS GSE108025.ARID2.Aska-SS 107 bp overlap
ASH2L 1 dataset
ChIP WA01 ENCSR850KIP.ASH2L.WA01 184 bp overlap
ATF2 1 dataset
ChIP WA01 ENCSR000BQU.ATF2.WA01 50 bp overlap
ATRX 1 dataset
ChIP metastatic-neuroblastoma_CHLA90 GSE100148.ATRX.metastatic-neuroblastoma_CHLA90 133 bp overlap
BCOR 1 dataset
ChIP B-cell_GERMINAL_CENTER GSE43350.BCOR.B-cell_GERMINAL_CENTER 168 bp overlap
BRD1 1 dataset
ChIP HUES-64 GSE104059.BRD1.HUES-64 184 bp overlap
BRD2 5 datasets
ChIP MV4-11_IBET151_500nM GSE120715.BRD2.MV4-11_IBET151_500nM 110 bp overlap
ChIP SK-MEL-147_JQ1 GSE94488.BRD2.SK-MEL-147_JQ1 159 bp overlap
ChIP THP-1_DMSO-PMA GSE138084.BRD2.THP-1_DMSO-PMA 184 bp overlap
ChIP THP-1_iBET-BD2-PMA GSE138084.BRD2.THP-1_iBET-BD2-PMA 184 bp overlap
ChIP foreskin_NHM1-5 GSE94488.BRD2.foreskin_NHM1-5 134 bp overlap
BRD3 7 datasets
ChIP HEK293T GSE39579.BRD3.HEK293T 167 bp overlap
ChIP THP-1_iBET GSE138084.BRD3.THP-1_iBET 184 bp overlap
ChIP THP-1_iBET-BD1-PMA GSE138084.BRD3.THP-1_iBET-BD1-PMA 184 bp overlap
ChIP THP-1_iBET-BD2-PMA GSE138084.BRD3.THP-1_iBET-BD2-PMA 184 bp overlap
ChIP U-87MG_GBM GSE99171.BRD3.U-87MG_GBM 178 bp overlap
ChIP U-87MG_GBM_dBET6_1d GSE99171.BRD3.U-87MG_GBM_dBET6_1d 120 bp overlap
ChIP U-87MG_GBM_dBET6_2h GSE99171.BRD3.U-87MG_GBM_dBET6_2h 108 bp overlap
BRD4 10 datasets
ChIP CLL_patient2 GSE109411.BRD4.CLL_patient2 160 bp overlap
ChIP HEK293_Ctrl GSE129407.BRD4.HEK293_Ctrl 99 bp overlap
ChIP HEK293_sgNT GSE129407.BRD4.HEK293_sgNT 92 bp overlap
ChIP HUVEC-C_modETS1 GSE93030.BRD4.HUVEC-C_modETS1 184 bp overlap
ChIP MPNST_PDJQ GSE62499.BRD4.MPNST_PDJQ 76 bp overlap
ChIP SUM1315_DMSO GSE63581.BRD4.SUM1315_DMSO 61 bp overlap
ChIP THP-1_iBET GSE138084.BRD4.THP-1_iBET 184 bp overlap
ChIP THP-1_iBET-BD1 GSE138084.BRD4.THP-1_iBET-BD1 184 bp overlap
ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 184 bp overlap
ChIP retina_AB1-FW20 GSE86981.BRD4.retina_AB1-FW20 108 bp overlap
CBX2 1 dataset
ChIP K-562 ENCSR000ATU.CBX2.K-562 184 bp overlap
CDK8 1 dataset
ChIP MOLM-14 GSE65138.CDK8.MOLM-14 160 bp overlap
CDK9 1 dataset
ChIP HCT-116 GSE72622.CDK9.HCT-116 115 bp overlap
CHD1 2 datasets
ChIP WA01 ENCSR000AQK.CHD1.WA01 62 bp overlap
ChIP WA01 ENCSR000AQK.CHD1.WA01 73 bp overlap
CTBP2 1 dataset
ChIP WA01 ENCSR000EUO.CTBP2.WA01 181 bp overlap
CTCF 4 datasets
ChIP chondrocyte ENCFF134ORZ 65 bp overlap
ChIP chondrocyte ENCFF134ORZ 184 bp overlap
ChIP right atrium auricular region ENCFF696NTN 184 bp overlap
ChIP type B pancreatic cell ENCFF910FNQ 147 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF262VBH 184 bp overlap
E2F1 1 dataset
ChIP U-87MG_GBM GSE99171.E2F1.U-87MG_GBM 184 bp overlap
E2F6 1 dataset
ChIP H1 ENCFF785DWK 152 bp overlap
EED 1 dataset
ChIP ProEs GSE59087.EED.ProEs 184 bp overlap
ESR1 1 dataset
ChIP MCF-7_PaPE-1_OA GSE93510.ESR1.MCF-7_PaPE-1_OA 123 bp overlap
ETS1 8 datasets
ChIP HUVEC-C_12h GSE93030.ETS1.HUVEC-C_12h 184 bp overlap
ChIP HUVEC-C_1h GSE93030.ETS1.HUVEC-C_1h 81 bp overlap
ChIP HUVEC-C_VEGF_12H GSE41166.ETS1.HUVEC-C_VEGF_12H 184 bp overlap
ChIP HUVEC-C_VEGF_12h GSE109625.ETS1.HUVEC-C_VEGF_12h 184 bp overlap
ChIP HUVEC-C_VEGF_1H GSE41166.ETS1.HUVEC-C_VEGF_1H 82 bp overlap
ChIP HUVEC-C_VEGF_1h GSE109625.ETS1.HUVEC-C_VEGF_1h 81 bp overlap
ChIP HUVEC-C_VEGF_4H GSE41166.ETS1.HUVEC-C_VEGF_4H 59 bp overlap
ChIP cardiomyocyte_D9 GSE129986.ETS1.cardiomyocyte_D9 98 bp overlap
EZH2 21 datasets
ChIP A673 ENCFF790MVL 165 bp overlap
ChIP A673 ENCFF790MVL 165 bp overlap
ChIP A673 ENCFF955JRZ 129 bp overlap
ChIP B-cell ENCSR000AUZ.EZH2.B-cell 184 bp overlap
ChIP GM23338 ENCFF613YON 155 bp overlap
ChIP GM23338 ENCSR045YHA.EZH2.GM23338 184 bp overlap
ChIP KG-1_shPLZF GSE109619.EZH2.KG-1_shPLZF 67 bp overlap
ChIP LNCaP-abl GSE39459.EZH2.LNCaP-abl 184 bp overlap
ChIP PC-3 ENCFF928VSN 184 bp overlap
ChIP SK-N-MC ENCFF434OHW 184 bp overlap
ChIP SK-N-MC ENCFF434OHW 171 bp overlap
ChIP SK-N-MC ENCFF674XUJ 184 bp overlap
ChIP astrocyte ENCSR000ARR.EZH2.astrocyte 171 bp overlap
ChIP dermal-fibroblast_Preneoplastic GSE126396.EZH2.dermal-fibroblast_Preneoplastic 81 bp overlap
ChIP dermal-fibroblast_Transformed GSE126396.EZH2.dermal-fibroblast_Transformed 184 bp overlap
ChIP dermal-fibroblast_Untransformed GSE126396.EZH2.dermal-fibroblast_Untransformed 184 bp overlap
ChIP hepatocyte ENCFF552DZB 184 bp overlap
ChIP hepatocyte ENCFF552DZB 184 bp overlap
ChIP mammary epithelial cell ENCFF224GAI 184 bp overlap
ChIP mammary epithelial cell ENCFF224GAI 157 bp overlap
ChIP peripheral-blood-mononuclear-cell_B-cell GSE115772.EZH2.peripheral-blood-mononuclear-cell_B-cell 156 bp overlap
EZH2_phosphoT487 2 datasets
ChIP PC-3 ENCSR617RSQ.EZH2_phosphoT487.PC-3 184 bp overlap
ChIP hepatocyte ENCSR341VYI.EZH2_phosphoT487.hepatocyte 184 bp overlap
GATA6 1 dataset
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 62 bp overlap
HDAC1 1 dataset
ChIP PC-3 GSE147455.HDAC1.PC-3 141 bp overlap
HDAC2 3 datasets
ChIP RH4_Entinostat-6H GSE116344.HDAC2.RH4_Entinostat-6H 61 bp overlap
ChIP WA01 ENCSR000AVB.HDAC2.WA01 184 bp overlap
ChIP WA01 ENCSR000BNR.HDAC2.WA01 89 bp overlap
HDAC3 1 dataset
ChIP RH4_DMSO-6H GSE116344.HDAC3.RH4_DMSO-6H 72 bp overlap
JARID2 3 datasets
ChIP MRC-5_IPS25_MEG3 GSE48515.JARID2.MRC-5_IPS25_MEG3 184 bp overlap
ChIP UTEIPS6 GSE48516.JARID2.UTEIPS6 124 bp overlap
ChIP UTEIPS7 GSE48516.JARID2.UTEIPS7 184 bp overlap
JUN 4 datasets
ChIP DE_D2 S02-DE-d2-JUN-exp1 103 bp overlap
ChIP ESC S24-ESC-d0-JUN-exp1 105 bp overlap
ChIP HUES-8 GSE109524.JUN.HUES-8 102 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 140 bp overlap
KDM1A 1 dataset
ChIP pancreatic-progenitor_GT GSE104840.KDM1A.pancreatic-progenitor_GT 184 bp overlap
KDM4C 1 dataset
ChIP SW1783 GSE92483.KDM4C.SW1783 158 bp overlap
KMT2A 4 datasets
ChIP HEK293T_C-term_C104 GSE90762.KMT2A.HEK293T_C-term_C104 150 bp overlap
ChIP HEK293T_N-term_C49 GSE90762.KMT2A.HEK293T_N-term_C49 149 bp overlap
ChIP MOLM-13_CBS79-KO-VP-HOTTIP GSE114981.KMT2A.MOLM-13_CBS79-KO-VP-HOTTIP 79 bp overlap
ChIP THP-1 GSE79899.KMT2A.THP-1 168 bp overlap
MAX 1 dataset
ChIP WTC11 ENCFF223QFY 184 bp overlap
MAZ 1 dataset
ChIP IMR-90 ENCSR000EFF.MAZ.IMR-90 94 bp overlap
MED1 4 datasets
ChIP G296S_4 GSE85628.MED1.G296S_4 184 bp overlap
ChIP HUVEC-C_siCTL GSE124892.MED1.HUVEC-C_siCTL 184 bp overlap
ChIP MOLM-14_DHE GSE124963.MED1.MOLM-14_DHE 175 bp overlap
ChIP MOLM-14_Veh GSE124963.MED1.MOLM-14_Veh 184 bp overlap
MED26 1 dataset
ChIP HEK293T GSE121024.MED26.HEK293T 107 bp overlap
MITF 1 dataset
ChIP melanocyte_CTR GSE50681.MITF.melanocyte_CTR 149 bp overlap
MLLT3 2 datasets
ChIP CD34 GSE54344.MLLT3.CD34 184 bp overlap
ChIP THP-1 GSE79899.MLLT3.THP-1 184 bp overlap
MXI1 2 datasets
ChIP IMR-90 ENCSR000EFE.MXI1.IMR-90 136 bp overlap
ChIP neural cell ENCFF623HQN 184 bp overlap
MYC 1 dataset
ChIP SK-N-SH GSE138295.MYC.SK-N-SH 62 bp overlap
MYCN 3 datasets
ChIP COG-N-415 GSE138295.MYCN.COG-N-415 94 bp overlap
ChIP LA-N-5 GSE138295.MYCN.LA-N-5 184 bp overlap
ChIP NB-1643 GSE138295.MYCN.NB-1643 184 bp overlap
MYOD1 2 datasets
ChIP IMR-90_GM GSE128527.MYOD1.IMR-90_GM 137 bp overlap
ChIP RD_shSNAI2 GSE137168.MYOD1.RD_shSNAI2 184 bp overlap
NANOG 1 dataset
ChIP HUES-8 GSE109524.NANOG.HUES-8 142 bp overlap
NR2F2 1 dataset
ChIP MCF-7_Veh GSE132432.NR2F2.MCF-7_Veh 184 bp overlap
NUTM1 1 dataset
ChIP embryonic-kidney_induced GSE133122.NUTM1.embryonic-kidney_induced 184 bp overlap
OGG1 1 dataset
ChIP HEK293 GSE89017.OGG1.HEK293 184 bp overlap
PHIP 1 dataset
ChIP HEK293_ab833 GSE101646.PHIP.HEK293_ab833 104 bp overlap
PLAG1 1 dataset
ChIP K-562 GSE111469.PLAG1.K-562 96 bp overlap
POLR2A 6 datasets
ChIP PFSK-1 ENCFF576NIT 65 bp overlap
ChIP breast epithelium ENCFF045XXN 141 bp overlap
ChIP breast epithelium ENCFF065JSZ 117 bp overlap
ChIP breast epithelium ENCFF960NNA 55 bp overlap
ChIP neural cell ENCFF604SPB 80 bp overlap
ChIP vagina ENCFF384GAB 184 bp overlap
POU5F1 3 datasets
ChIP DE_D1 DED1-OCT4_Batch_II 136 bp overlap
ChIP HUES-8 GSE109524.POU5F1.HUES-8 184 bp overlap
ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 158 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 53 bp overlap
PRDM14 1 dataset
ChIP NCCIT GSE71675.PRDM14.NCCIT 184 bp overlap
RAD21 7 datasets
ChIP HEK293_siCtrl GSE130135.RAD21.HEK293_siCtrl 162 bp overlap
ChIP HUVEC-C_hypoxia GSE94872.RAD21.HUVEC-C_hypoxia 184 bp overlap
ChIP IMR-90 ENCSR000EFJ.RAD21.IMR-90 184 bp overlap
ChIP THP-1_Pam3csk-000m-Flavo-000m GSE103477.RAD21.THP-1_Pam3csk-000m-Flavo-000m 176 bp overlap
ChIP THP-1_Pam3csk-000m-Flavo-240m GSE103477.RAD21.THP-1_Pam3csk-000m-Flavo-240m 166 bp overlap
ChIP THP-1_Pam3csk-120m-Flavo-000m GSE103477.RAD21.THP-1_Pam3csk-120m-Flavo-000m 160 bp overlap
ChIP THP-1_Pam3csk-360m-Flavo-240m GSE103477.RAD21.THP-1_Pam3csk-360m-Flavo-240m 184 bp overlap
RBBP5 1 dataset
ChIP WA01 ENCSR000AQC.RBBP5.WA01 146 bp overlap
RELA 6 datasets
ChIP HAEC_TNFa_4h GSE89970.RELA.HAEC_TNFa_4h 97 bp overlap
ChIP aortic-endothelial-cell_IL1B_D14 GSE139377.RELA.aortic-endothelial-cell_IL1B_D14 184 bp overlap
ChIP aortic-endothelial-cell_IL1B_D16 GSE139377.RELA.aortic-endothelial-cell_IL1B_D16 114 bp overlap
ChIP aortic-endothelial-cell_IL1B_D21 GSE139377.RELA.aortic-endothelial-cell_IL1B_D21 136 bp overlap
ChIP aortic-endothelial-cell_IL1B_D8 GSE139377.RELA.aortic-endothelial-cell_IL1B_D8 151 bp overlap
ChIP aortic-endothelial-cell_IL1B_D9 GSE139377.RELA.aortic-endothelial-cell_IL1B_D9 146 bp overlap
REST 1 dataset
ChIP neural ENCSR000BTV.REST.neural 184 bp overlap
RNF2 1 dataset
ChIP HMELBRAF_OVER GSE51929.RNF2.HMELBRAF_OVER 118 bp overlap
SAP30 1 dataset
ChIP WA01 ENCSR000ATR.SAP30.WA01 184 bp overlap
SIN3A 3 datasets
ChIP H1 ENCFF042ZSL 184 bp overlap
ChIP HUVEC-C GSE103245.SIN3A.HUVEC-C 70 bp overlap
ChIP PFSK1 ENCSR000BOY.SIN3A.PFSK1 95 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 126 bp overlap
ChIP HUVEC-C_TGFB1 GSE134556.SMAD2-3.HUVEC-C_TGFB1 176 bp overlap
SMARCA4 3 datasets
ChIP HS-SY-2_HA-tagged GSE108926.SMARCA4.HS-SY-2_HA-tagged 184 bp overlap
ChIP NSC GSE125033.SMARCA4.NSC 184 bp overlap
ChIP TTC-1240_SMARCB1-FL GSE124903.SMARCA4.TTC-1240_SMARCB1-FL 184 bp overlap
SMARCB1 2 datasets
ChIP hiPSC GSE124903.SMARCB1.hiPSC 98 bp overlap
ChIP proliferating-human-fibroblast_ASO_Ctrl GSE131711.SMARCB1.proliferating-human-fibroblast_ASO_Ctrl 130 bp overlap
SMARCC1 8 datasets
ChIP Aska-SS_shSSX GSE108025.SMARCC1.Aska-SS_shSSX 184 bp overlap
ChIP HS-SY-2 GSE108025.SMARCC1.HS-SY-2 184 bp overlap
ChIP SYO-1_shCt GSE139053.SMARCC1.SYO-1_shCt 184 bp overlap
ChIP SYO-1_shRING1A-B GSE139053.SMARCC1.SYO-1_shRING1A-B 164 bp overlap
ChIP TTC-1240 GSE124903.SMARCC1.TTC-1240 91 bp overlap
ChIP TTC-1240_R377H GSE124903.SMARCC1.TTC-1240_R377H 184 bp overlap
ChIP TTC-1240_SMARCB1-FL GSE124903.SMARCC1.TTC-1240_SMARCB1-FL 167 bp overlap
ChIP TTC-1240_delC GSE124903.SMARCC1.TTC-1240_delC 184 bp overlap
SMC3 1 dataset
ChIP IMR-90 ENCFF627LON 96 bp overlap
SS18 2 datasets
ChIP SYO-1 GSE108025.SS18.SYO-1 184 bp overlap
ChIP SYO-1_shRING1A-B GSE139053.SS18.SYO-1_shRING1A-B 176 bp overlap
STAG2 1 dataset
ChIP HCAEC GSE101921.STAG2.HCAEC 61 bp overlap
SUZ12 3 datasets
ChIP CRL-7250_shSS18 GSE108025.SUZ12.CRL-7250_shSS18 184 bp overlap
ChIP GM12878 ENCSR744XTG.SUZ12.GM12878 97 bp overlap
ChIP LNCaP-abl GSE39459.SUZ12.LNCaP-abl 184 bp overlap
TAF1 2 datasets
ChIP WA01 ENCSR000BHO.TAF1.WA01 184 bp overlap
ChIP neural ENCSR000BTX.TAF1.neural 98 bp overlap
TFAP2C 2 datasets
ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 74 bp overlap
ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 182 bp overlap
TP53 2 datasets
ChIP hESC_DAMAGED GSE39912.TP53.hESC_DAMAGED 82 bp overlap
ChIP lymphocyte_90 GSE110368.TP53.lymphocyte_90 83 bp overlap
TRIM24 1 dataset
ChIP MOLM-13_IACS-9571 GSE100571.TRIM24.MOLM-13_IACS-9571 184 bp overlap
USF2 1 dataset
ChIP IMR-90 ENCFF438KUN 54 bp overlap
ZBTB20 1 dataset
ChIP HEK293 ENCSR460MBI.ZBTB20.HEK293 71 bp overlap
ZBTB33 1 dataset
ChIP K-562 ENCSR876GXA.ZBTB33.K-562 184 bp overlap
ZEB1 1 dataset
ChIP HEK293 ENCSR909HMT.ZEB1.HEK293 129 bp overlap
ZFX 1 dataset
ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 101 bp overlap
ZNF148 1 dataset
ChIP K-562 GSE121133.ZNF148.K-562 73 bp overlap
ZNF281 1 dataset
ChIP K-562 GSE121133.ZNF281.K-562 62 bp overlap
ZNF335 1 dataset
ChIP HEK293 ENCSR328SUD.ZNF335.HEK293 163 bp overlap
ZNF513 1 dataset
ChIP HEK293 ENCSR503DPC.ZNF513.HEK293 57 bp overlap
ZNF736 1 dataset
ChIP HEK293T GSE78099.ZNF736.HEK293T 57 bp overlap
ZSCAN30 1 dataset
ChIP HEK293 ENCSR768VNZ.ZSCAN30.HEK293 115 bp overlap
Huangfu Lab · Publications · Resources · Contact