chr17:59,370,634–59,371,353

chr17 : 59,370,634 – 59,371,353

719 bp 95 TFs 9 linked genes

This 719 bp open chromatin element is linked to 9 target genes and is bound by 95 transcription factors.

Linked Genes

9 genes

Gene	Expression	Dist. to TSS	Distance	Link type
YPEL2		39.2 kb	Distal	Multiome
GDPD1		150.4 kb	Distal	Multiome
SMG8		160.9 kb	Distal	Multiome
DHX40		194.7 kb	Distal	Multiome
PRR11		215.2 kb	Distal	Multiome
SKA2		215.7 kb	Distal	Multiome
CLTC		249.0 kb	Distal	Multiome
TRIM37		264.2 kb	Distal	Multiome
ENSG00000224738		264.3 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

95 transcription factors

ChIP MCF-7 GSE48930.AR.MCF-7 165 bp overlap

ChIP MCF-7 GSE48930.AR.MCF-7 197 bp overlap

ARID1A 1 dataset

ChIP RMG-I GSE104545.ARID1A.RMG-I 225 bp overlap

ChIP 501-mel GSE95280.ARNT.501-mel 384 bp overlap

BACH2 1 dataset

ChIP B-cell_IL2 GSE102460.BACH2.B-cell_IL2 321 bp overlap

BRD2 2 datasets

ChIP THP-1_iBET GSE138084.BRD2.THP-1_iBET 327 bp overlap

ChIP THP-1_iBET-BD2 GSE138084.BRD2.THP-1_iBET-BD2 518 bp overlap

BRD3 2 datasets

ChIP MV4-11_DMSO GSE120715.BRD3.MV4-11_DMSO 408 bp overlap

ChIP MV4-11_IBET151_50nM GSE120715.BRD3.MV4-11_IBET151_50nM 201 bp overlap

BRD4 11 datasets

ChIP CLL_patient1_4h_CpG GSE109411.BRD4.CLL_patient1_4h_CpG 321 bp overlap

ChIP LNCaP-C4-2_F133V GSE88871.BRD4.LNCaP-C4-2_F133V 159 bp overlap

ChIP MV4-11-B_DMSO GSE101821.BRD4.MV4-11-B_DMSO 284 bp overlap

ChIP MV4-11_DMSO GSE71776.BRD4.MV4-11_DMSO 93 bp overlap

ChIP MV4-11_DMSO GSE71776.BRD4.MV4-11_DMSO 191 bp overlap

ChIP SEM GSE83671.BRD4.SEM 121 bp overlap

ChIP SUM159PT_scramble GSE131097.BRD4.SUM159PT_scramble 57 bp overlap

ChIP THP-1_iBET-BD2 GSE138084.BRD4.THP-1_iBET-BD2 612 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 719 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 308 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 200 bp overlap

CDK9 4 datasets

ChIP BT-474 ERP010664.CDK9.BT-474 165 bp overlap

ChIP BT-474_INHHDAC ERP010664.CDK9.BT-474_INHHDAC 154 bp overlap

ChIP BT-474_INHHDAC ERP010664.CDK9.BT-474_INHHDAC 317 bp overlap

ChIP BT-474_INHHDAC ERP010664.CDK9.BT-474_INHHDAC 97 bp overlap

ChIP RH5 GSE155861.CHD4.RH5 220 bp overlap

CHD8 2 datasets

ChIP T-47D_ETOH_45 GSE62428.CHD8.T-47D_ETOH_45 177 bp overlap

ChIP T-47D_ETOH_45 GSE62428.CHD8.T-47D_ETOH_45 60 bp overlap

CREB1 1 dataset

ChIP MDA-MB-134-VI GSE109103.CREB1.MDA-MB-134-VI 254 bp overlap

ChIP retina_Hu20 GSE137311.CRX.retina_Hu20 202 bp overlap

ChIP retina_Hu3 GSE137311.CRX.retina_Hu3 201 bp overlap

ChIP retina_Hu6 GSE137311.CRX.retina_Hu6 624 bp overlap

CTCF 5 datasets

ChIP A-549 ENCSR000DPF.CTCF.A-549 174 bp overlap

ChIP kidney ENCFF335EKK 185 bp overlap

ChIP retina_Hu22 GSE137311.CTCF.retina_Hu22 249 bp overlap

ChIP retina_Hu25 GSE137311.CTCF.retina_Hu25 272 bp overlap

ChIP retina_Hu6 GSE137311.CTCF.retina_Hu6 361 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 204 bp overlap

ESR1 13 datasets

ChIP Ishikawa_siETV4-72h GSE129803.ESR1.Ishikawa_siETV4-72h 468 bp overlap

ChIP Ishikawa_siNTC-72h GSE129803.ESR1.Ishikawa_siNTC-72h 391 bp overlap

ChIP Ishikawa_siNTC-96h GSE129803.ESR1.Ishikawa_siNTC-96h 406 bp overlap

ChIP MCF-7_DHT GSE99626.ESR1.MCF-7_DHT 469 bp overlap

ChIP MCF-7_SHCTR_E2_TNF GSE59530.ESR1.MCF-7_SHCTR_E2_TNF 209 bp overlap

ChIP MCF-7_TamR GSE128445.ESR1.MCF-7_TamR 222 bp overlap

ChIP MCF-7_Veh GSE93510.ESR1.MCF-7_Veh 274 bp overlap

ChIP MCF-7_aldosterone GSE99626.ESR1.MCF-7_aldosterone 369 bp overlap

ChIP MCF-7_estradiol-DHT_45min GSE99626.ESR1.MCF-7_estradiol-DHT_45min 207 bp overlap

ChIP MCF-7_estradiol_45min_H4 GSE99626.ESR1.MCF-7_estradiol_45min_H4 317 bp overlap

ChIP MCF-7_shCtrl_TamR GSE128445.ESR1.MCF-7_shCtrl_TamR 234 bp overlap

ChIP breast_tumor_Male_21 GSE104399.ESR1.breast_tumor_Male_21 196 bp overlap

ChIP breast_tumor_Male_21 GSE104399.ESR1.breast_tumor_Male_21 227 bp overlap

ESRRG 1 dataset

ChIP cardiomyocyte GSE113760.ESRRG.cardiomyocyte 400 bp overlap

EZH2 2 datasets

ChIP RH30_DMSO GSE85169.EZH2.RH30_DMSO 387 bp overlap

ChIP neural progenitor cell ENCFF018MKA 289 bp overlap

FIGLA 1 dataset

Motif DE_72h DE_72h-FIGLA_MA0820.2 6 bp overlap

ChIP SKNO-1 GSE23730.FLI1.SKNO-1 238 bp overlap

FOXA1 1 dataset

ChIP breast-cancer_heregulin GSE101407.FOXA1.breast-cancer_heregulin 285 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 401 bp overlap

ChIP DE DE-FOXA2-2 474 bp overlap

GATA2 1 dataset

ChIP ME-1_CBFB-MYH11-KD GSE117138.GATA2.ME-1_CBFB-MYH11-KD 316 bp overlap

GATA3 1 dataset

ChIP breast_tumor_Male_21 GSE104399.GATA3.breast_tumor_Male_21 201 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 715 bp overlap

ChIP DE DE-GATA4-2 719 bp overlap

GATA6 8 datasets

ChIP DE DE-GATA6-1 379 bp overlap

ChIP DE DE-GATA6-1 259 bp overlap

ChIP DE DE-GATA6-2 719 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 388 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 279 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 410 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 291 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 326 bp overlap

GLYR1 1 dataset

ChIP HepG2 ENCFF114PDZ 249 bp overlap

HAND2 1 dataset

ChIP Kelly GSE94822.HAND2.Kelly 216 bp overlap

HNF1B 1 dataset

ChIP foregut GSE117136.HNF1B.foregut 420 bp overlap

HNRNPH1 2 datasets

ChIP Hep-G2 GSE120104.HNRNPH1.Hep-G2 117 bp overlap

ChIP Hep-G2 ENCSR066FXN.HNRNPH1.Hep-G2 64 bp overlap

IRF5 2 datasets

ChIP HepG2 ENCFF817YVE 561 bp overlap

ChIP HepG2 ENCFF817YVE 201 bp overlap

ChIP OCI-AML-3 GSE133516.KAT7.OCI-AML-3 719 bp overlap

KDM5B 2 datasets

ChIP HepG2 ENCFF706LUI 502 bp overlap

ChIP HepG2 ENCFF706LUI 302 bp overlap

Motif DE_72h DE_72h-MAZ_MA1522.2 8 bp overlap

MED1 5 datasets

ChIP G296S_4 GSE85628.MED1.G296S_4 319 bp overlap

ChIP G296S_4 GSE85628.MED1.G296S_4 152 bp overlap

ChIP HUVEC-C_siCTL GSE124892.MED1.HUVEC-C_siCTL 719 bp overlap

ChIP HUVEC-C_siERG GSE124892.MED1.HUVEC-C_siERG 58 bp overlap

ChIP HUVEC-C_siERG GSE124892.MED1.HUVEC-C_siERG 214 bp overlap

MED26 1 dataset

ChIP U2OS_SHEP400 GSE73742.MED26.U2OS_SHEP400 313 bp overlap

MEF2D 2 datasets

ChIP retina_Hu13 GSE137311.MEF2D.retina_Hu13 420 bp overlap

ChIP retina_Hu25 GSE137311.MEF2D.retina_Hu25 484 bp overlap

ChIP HepG2 ENCFF938KYA 246 bp overlap

MTA1 2 datasets

ChIP Hep-G2 ENCSR983KRB.MTA1.Hep-G2 168 bp overlap

ChIP HepG2 ENCFF038CCB 346 bp overlap

ChIP MCF-7 ENCFF767RTQ 205 bp overlap

MYOD1 1 dataset

Motif DE_72h DE_72h-MYOD1_MA0499.3 9 bp overlap

NCOA1 1 dataset

ChIP HepG2 ENCFF624JES 643 bp overlap

NEUROD1 2 datasets

ChIP D341-Med_shGFP GSE92582.NEUROD1.D341-Med_shGFP 719 bp overlap

ChIP D341-Med_shNEUROD1-1579 GSE92582.NEUROD1.D341-Med_shNEUROD1-1579 250 bp overlap

NEUROG2 3 datasets

ChIP MRC-5_NFD_02DPT GSE75910.NEUROG2.MRC-5_NFD_02DPT 120 bp overlap

ChIP MRC-5_NFD_05DPT GSE75910.NEUROG2.MRC-5_NFD_05DPT 54 bp overlap

ChIP MRC-5_NFD_1DPT GSE75910.NEUROG2.MRC-5_NFD_1DPT 84 bp overlap

NKX2-1 1 dataset

ChIP H9_derived-cIN GSE99937.NKX2-1.H9_derived-cIN 185 bp overlap

NOTCH3 1 dataset

ChIP TALL-1_DMSO GSE104261.NOTCH3.TALL-1_DMSO 179 bp overlap

NR3C1 1 dataset

ChIP breast_tumor_Male_21 GSE104399.NR3C1.breast_tumor_Male_21 195 bp overlap

ChIP retina_Hu13 GSE137311.NRL.retina_Hu13 571 bp overlap

ChIP retina_Hu7 GSE137311.OTX2.retina_Hu7 661 bp overlap

PATZ1 1 dataset

Motif DE_72h DE_72h-PATZ1_MA1961.2 11 bp overlap

ChIP MCF-7_R5020 GSE68355.PGR.MCF-7_R5020 190 bp overlap

PLAG1 1 dataset

Motif DE_72h DE_72h-PLAG1_MA0163.1 14 bp overlap

POLR2A 6 datasets

ChIP MCF-7 ENCFF411WCU 215 bp overlap

ChIP gastrocnemius medialis ENCFF081DTE 505 bp overlap

ChIP gastrocnemius medialis ENCFF145VIB 372 bp overlap

ChIP heart left ventricle ENCFF591JWH 54 bp overlap

ChIP spleen ENCFF028DPU 251 bp overlap

ChIP uterus ENCFF208ADI 50 bp overlap

POU4F2 1 dataset

ChIP HNPC_DIF GSE74814.POU4F2.HNPC_DIF 84 bp overlap

PPARG 1 dataset

ChIP ASC GSE21366.PPARG.ASC 198 bp overlap

Ptf1A 1 dataset

Motif DE_72h DE_72h-Ptf1A_MA1620.2 8 bp overlap

RAD21 1 dataset

ChIP THP-1_PMA_IFNb-6h GSE103477.RAD21.THP-1_PMA_IFNb-6h 196 bp overlap

ChIP retina_Hu22 GSE137311.RORB.retina_Hu22 646 bp overlap

ChIP HepG2 ENCFF763IEA 253 bp overlap

SIX2 2 datasets

ChIP HEK GSE73865.SIX2.HEK 460 bp overlap

ChIP kidney_fetal_17w GSE75948.SIX2.kidney_fetal_17w 422 bp overlap

SMAD1 1 dataset

ChIP Hep-G2 ENCSR213QOZ.SMAD1.Hep-G2 185 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 153 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 719 bp overlap

SMAD2_3 3 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 331 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 275 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 369 bp overlap

SMAD3 1 dataset

ChIP H69_4TGF GSE145250.SMAD3.H69_4TGF 110 bp overlap

SMARCA5 1 dataset

ChIP GM12878 ENCSR706YUH.SMARCA5.GM12878 314 bp overlap

SNAI2 1 dataset

Motif DE_72h DE_72h-SNAI2_MA0745.3 8 bp overlap

ChIP HepG2 ENCFF767OCK 466 bp overlap

SPI1 2 datasets

ChIP GM12891 ENCFF563IUT 241 bp overlap

ChIP THP-1 GSE128834.SPI1.THP-1 117 bp overlap

STAT3 1 dataset

ChIP B-cell GSE123398.STAT3.B-cell 178 bp overlap

TBL1X 1 dataset

ChIP HEK293T GSE35197.TBL1X.HEK293T 183 bp overlap

TBX5 3 datasets

ChIP G296S_4 GSE85628.TBX5.G296S_4 212 bp overlap

ChIP G296S_4 GSE85628.TBX5.G296S_4 213 bp overlap

ChIP cardiomyocyte_7 GSE85628.TBX5.cardiomyocyte_7 244 bp overlap

TEAD4 1 dataset

ChIP hMSC-TERT4 GSE140782.TEAD4.hMSC-TERT4 205 bp overlap

ChIP kidney-cortex GSE129585.VDR.kidney-cortex 719 bp overlap

ZBTB11 2 datasets

ChIP K562 ENCFF694AXU 317 bp overlap

ChIP K562 ENCFF694AXU 111 bp overlap

ZBTB38 1 dataset

ChIP HepG2 ENCFF875UQX 275 bp overlap

ZBTB7A 1 dataset

ChIP VCaP_FBS GSE123089.ZBTB7A.VCaP_FBS 303 bp overlap

Motif DE_72h DE_72h-ZEB1_MA0103.4 6 bp overlap

ChIP HEK293T_22Rv1 GSE145160.ZFX.HEK293T_22Rv1 465 bp overlap

ChIP HEK293 ENCFF033NQQ 471 bp overlap

ZNF148 1 dataset

Motif DE_72h DE_72h-ZNF148_MA1653.2 10 bp overlap

ZNF276 1 dataset

ChIP HepG2 ENCFF431WQQ 261 bp overlap

ChIP K-562 ENCSR195QFV.ZNF3.K-562 87 bp overlap

ZNF407 2 datasets

ChIP Hep-G2 ENCSR005WGY.ZNF407.Hep-G2 179 bp overlap

ChIP Hep-G2 ENCSR005WGY.ZNF407.Hep-G2 353 bp overlap

ZNF501 1 dataset

ChIP Hep-G2 ENCSR227PHM.ZNF501.Hep-G2 261 bp overlap

ZNF512B 1 dataset

ChIP MCF-7 ENCFF233IPF 69 bp overlap

ZNF550 1 dataset

ChIP Hep-G2 ENCSR198BHH.ZNF550.Hep-G2 383 bp overlap

ZNF572 1 dataset

ChIP Hep-G2 ENCSR663CTC.ZNF572.Hep-G2 249 bp overlap

ZNF598 2 datasets

ChIP Hep-G2 ENCSR173NAL.ZNF598.Hep-G2 234 bp overlap

ChIP Hep-G2 ENCSR173NAL.ZNF598.Hep-G2 260 bp overlap

ZNF600 1 dataset

ChIP HEK293 ENCFF785JSX 123 bp overlap

ZNF605 1 dataset

ChIP HEK293T GSE78099.ZNF605.HEK293T 256 bp overlap

ZNF687 2 datasets

ChIP HepG2 ENCFF653WIX 457 bp overlap

ChIP HepG2 ENCFF653WIX 203 bp overlap

ZNF709 1 dataset

ChIP HepG2 ENCFF151DHM 143 bp overlap

Zic1::Zic2 1 dataset

Motif DE_72h DE_72h-Zic1Zic2_MA1628.2 7 bp overlap

Motif DE_72h DE_72h-Zic2_MA1629.2 9 bp overlap

Motif DE_72h DE_72h-Zic3_MA0697.3 7 bp overlap