chr16:57,256,968–57,257,582

chr16 : 57,256,968 – 57,257,582

614 bp 94 TFs 8 linked genes

This 614 bp open chromatin element is linked to 8 target genes and is bound by 94 transcription factors.

Linked Genes

8 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ARL2BP		12.0 kb	Distal	Multiome
RSPRY1		70.9 kb	Distal	Multiome
PSME3IP1		71.2 kb	Distal	Multiome
CPNE2		164.6 kb	Distal	Multiome
CIAPIN1		190.2 kb	Distal	Multiome
COQ9		190.3 kb	Distal	Multiome
POLR2C		205.4 kb	Distal	Multiome
CCDC102A		279.4 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

94 transcription factors

ChIP prostate_fetal-fibroblast GSE90772.AR.prostate_fetal-fibroblast 75 bp overlap

ARID1A 1 dataset

ChIP RMG-I GSE104545.ARID1A.RMG-I 515 bp overlap

ARID1B 2 datasets

ChIP K-562 ENCSR822CCM.ARID1B.K-562 378 bp overlap

ChIP K562 ENCFF938UXQ 338 bp overlap

ARID2 1 dataset

ChIP Aska-SS_shSSX GSE108025.ARID2.Aska-SS_shSSX 99 bp overlap

BCL11A 3 datasets

ChIP HUDEP-2_30min GSE104676.BCL11A.HUDEP-2_30min 194 bp overlap

ChIP HUDEP-2_30min GSE104676.BCL11A.HUDEP-2_30min 69 bp overlap

ChIP HUDEP-2_90min GSE104676.BCL11A.HUDEP-2_90min 294 bp overlap

BHLHA15 1 dataset

ChIP HepG2 ENCFF569DAY 425 bp overlap

BRD4 4 datasets

ChIP Jurkat GSE83777.BRD4.Jurkat 588 bp overlap

ChIP KOPT-K1 GSE54379.BRD4.KOPT-K1 614 bp overlap

ChIP KOPT-K1_E GSE54379.BRD4.KOPT-K1_E 277 bp overlap

ChIP MV4-11-B_BI00894999_100nM_4h GSE101821.BRD4.MV4-11-B_BI00894999_100nM_4h 338 bp overlap

CBFA2T2 2 datasets

ChIP K-562 ENCSR699PVC.CBFA2T2.K-562 452 bp overlap

ChIP K562 ENCFF963TXY 301 bp overlap

CBFA2T3 3 datasets

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 519 bp overlap

ChIP K-562 GSE142227.CBFA2T3.K-562 208 bp overlap

ChIP K562 ENCFF673OEZ 424 bp overlap

ChIP Jurkat GSE83777.CDK7.Jurkat 268 bp overlap

CDK9 2 datasets

ChIP MOLT-4_DMSO GSE79288.CDK9.MOLT-4_DMSO 276 bp overlap

ChIP MOLT-4_JQ1 GSE79288.CDK9.MOLT-4_JQ1 241 bp overlap

CDKN1B 1 dataset

ChIP MDA-MB-231_p27CK-DD GSE112444.CDKN1B.MDA-MB-231_p27CK-DD 97 bp overlap

CEBPD 1 dataset

ChIP K-562 ENCSR000BVY.CEBPD.K-562 240 bp overlap

CTBP1 2 datasets

ChIP K-562 ENCSR201NQZ.CTBP1.K-562 505 bp overlap

ChIP K562 ENCFF403WPG 493 bp overlap

ChIP HUDEP-2_30min GSE104676.CTCF.HUDEP-2_30min 125 bp overlap

Cebpa 3 datasets

ChIP BLaER1 ENCFF031ISE 51 bp overlap

ChIP BLaER1 ENCFF335XTP 140 bp overlap

ChIP BLaER1 ENCFF460KDD 73 bp overlap

DACH1 2 datasets

ChIP K-562 ENCSR030TJP.DACH1.K-562 203 bp overlap

ChIP K562 ENCFF574LOW 373 bp overlap

DNMT3B 3 datasets

ChIP HUES-8 GSE99346.DNMT3B.HUES-8 67 bp overlap

ChIP HUES-8_TripleKO-TET1-2-3 GSE99346.DNMT3B.HUES-8_TripleKO-TET1-2-3 246 bp overlap

ChIP HUES-8_TripleKO-TET1-2-3 GSE99346.DNMT3B.HUES-8_TripleKO-TET1-2-3 106 bp overlap

ChIP K-562 ENCSR219BXP.DPF2.K-562 205 bp overlap

ChIP ProEs GSE59087.EED.ProEs 153 bp overlap

ChIP ProEs GSE59087.EED.ProEs 160 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 334 bp overlap

EP300 2 datasets

ChIP K-562 ENCSR000EGE.EP300.K-562 175 bp overlap

ChIP K562 ENCFF226VMS 317 bp overlap

ChIP Jurkat GSE49091.ERG.Jurkat 459 bp overlap

ChIP SU-DHL-5 GSE45982.EZH2.SU-DHL-5 77 bp overlap

FOSL1 1 dataset

ChIP K-562 ENCSR239ZLZ.FOSL1.K-562 217 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 361 bp overlap

ChIP DE DE-FOXA2-2 465 bp overlap

FOXM1 2 datasets

ChIP K-562 ENCSR429QPP.FOXM1.K-562 246 bp overlap

ChIP K562 ENCFF255RHV 411 bp overlap

FOXO1 1 dataset

ChIP CD34 GSE80773.FOXO1.CD34 62 bp overlap

GABPA 1 dataset

ChIP K-562 ENCSR000BLO.GABPA.K-562 351 bp overlap

GATA1 10 datasets

ChIP CD34_Day7_30min GSE104676.GATA1.CD34_Day7_30min 212 bp overlap

ChIP CD34_ERYTH_BIO GSE29194.GATA1.CD34_ERYTH_BIO 124 bp overlap

ChIP CD34_ERYTH_BMP GSE29194.GATA1.CD34_ERYTH_BMP 110 bp overlap

ChIP HUDEP-2_30min GSE104676.GATA1.HUDEP-2_30min 272 bp overlap

ChIP K-562 GSE107726.GATA1.K-562 313 bp overlap

ChIP K-562 ENCSR000EFT.GATA1.K-562 213 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 264 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 241 bp overlap

ChIP K562 ENCFF094CMK 251 bp overlap

ChIP erythroblast ENCSR000EXP.GATA1.erythroblast 311 bp overlap

GATA2 12 datasets

ChIP CD34_ACY957 GSE60792.GATA2.CD34_ACY957 243 bp overlap

ChIP K-562 ENCSR000EWG.GATA2.K-562 265 bp overlap

ChIP K-562 ENCSR000DKA.GATA2.K-562 350 bp overlap

ChIP K-562 ENCSR000BKM.GATA2.K-562 245 bp overlap

ChIP K-562 ENCSR257RKC.GATA2.K-562 166 bp overlap

ChIP K562 ENCFF088XQT 411 bp overlap

ChIP K562 ENCFF088XQT 285 bp overlap

ChIP K562 ENCFF544PCK 251 bp overlap

ChIP ME-1_CBFB-MYH11-KD GSE117138.GATA2.ME-1_CBFB-MYH11-KD 589 bp overlap

ChIP SKH1 GSE87283.GATA2.SKH1 245 bp overlap

ChIP SKH1_RUNX1-EVI1_KD GSE87283.GATA2.SKH1_RUNX1-EVI1_KD 183 bp overlap

ChIP TF1 GSE73207.GATA2.TF1 219 bp overlap

GATA3 4 datasets

ChIP Jurkat GSE76181.GATA3.Jurkat 413 bp overlap

ChIP Jurkat GSE68976.GATA3.Jurkat 359 bp overlap

ChIP Jurkat GSE120063.GATA3.Jurkat 400 bp overlap

ChIP Jurkat GSE29180.GATA3.Jurkat 362 bp overlap

GATA4 4 datasets

ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.GATA4.BJ1-hTERT_FOXA2_GATA4_Coexp 203 bp overlap

ChIP DE DE-GATA4-1 570 bp overlap

ChIP DE DE-GATA4-2 611 bp overlap

ChIP foregut GSE117136.GATA4.foregut 519 bp overlap

GATA6 11 datasets

ChIP DE DE-GATA6-1 553 bp overlap

ChIP DE DE-GATA6-2 614 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 417 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 445 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 372 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 614 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 527 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 482 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 614 bp overlap

ChIP foregut GSE117136.GATA6.foregut 290 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 412 bp overlap

GFI1B 1 dataset

ChIP K-562 ENCSR509GDT.GFI1B.K-562 149 bp overlap

HDAC1 3 datasets

ChIP K-562 ENCSR387UWP.HDAC1.K-562 340 bp overlap

ChIP K-562_dilution-6-100 GSE140325.HDAC1.K-562_dilution-6-100 161 bp overlap

ChIP K562 ENCFF968WBH 163 bp overlap

HDAC2 4 datasets

ChIP K-562 ENCSR893WSB.HDAC2.K-562 374 bp overlap

ChIP K-562 ENCSR075HTM.HDAC2.K-562 234 bp overlap

ChIP K-562 GSE140325.HDAC2.K-562 177 bp overlap

ChIP K562 ENCFF744ALD 421 bp overlap

HNRNPLL 1 dataset

ChIP K-562 ENCSR112RNT.HNRNPLL.K-562 211 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 389 bp overlap

KDM1A 5 datasets

ChIP K-562 GSE117944.KDM1A.K-562 354 bp overlap

ChIP K-562 ENCSR908CMW.KDM1A.K-562 212 bp overlap

ChIP K-562_Wnt GSE117944.KDM1A.K-562_Wnt 212 bp overlap

ChIP K562 ENCFF128TYE 461 bp overlap

ChIP K562 ENCFF133OLU 461 bp overlap

KLF16 2 datasets

ChIP K-562 ENCSR760UVO.KLF16.K-562 221 bp overlap

ChIP K562 ENCFF464PIV 345 bp overlap

LDB1 2 datasets

ChIP HEP GSE52637.LDB1.HEP 221 bp overlap

ChIP K-562 GSE142227.LDB1.K-562 315 bp overlap

ChIP Jurkat GSE94391.LMO1.Jurkat 492 bp overlap

ChIP CCRF-CEM GSE33850.LMO2.CCRF-CEM 353 bp overlap

ChIP CD4_Th1 GSE72266.MAF.CD4_Th1 67 bp overlap

ChIP HUVEC-C_siERG GSE124892.MED1.HUVEC-C_siERG 614 bp overlap

MEIS2 1 dataset

ChIP K562 ENCFF320GSD 381 bp overlap

MTA2 2 datasets

ChIP K-562 ENCSR113LAS.MTA2.K-562 299 bp overlap

ChIP K562 ENCFF880VZB 341 bp overlap

ChIP DU528 GSE94000.MYB.DU528 341 bp overlap

ChIP Jurkat GSE59657.MYB.Jurkat 614 bp overlap

ChIP MOLT-3 GSE59657.MYB.MOLT-3 323 bp overlap

ChIP PF-382 GSE94000.MYB.PF-382 614 bp overlap

NCOR1 3 datasets

ChIP K-562 ENCSR798ILC.NCOR1.K-562 309 bp overlap

ChIP K-562 ENCSR910JAI.NCOR1.K-562 268 bp overlap

ChIP K562 ENCFF866HRM 148 bp overlap

NFIC 2 datasets

ChIP K-562 ENCSR796ITY.NFIC.K-562 215 bp overlap

ChIP K562 ENCFF167YID 178 bp overlap

ChIP K-562 GSE26439.NFYA.K-562 185 bp overlap

ChIP K-562 GSE26439.NFYB.K-562 269 bp overlap

NR2F2 1 dataset

ChIP K-562 ENCSR000BRS.NR2F2.K-562 177 bp overlap

NR3C1 1 dataset

ChIP K-562_GLUCC ERP007081.NR3C1.K-562_GLUCC 160 bp overlap

PKNOX1 2 datasets

ChIP K-562 ENCSR115SMW.PKNOX1.K-562 535 bp overlap

ChIP K562 ENCFF236IUS 203 bp overlap

ChIP K-562 ENCSR000BQY.PML.K-562 254 bp overlap

ChIP K562 ENCFF801LKH 505 bp overlap

POLR2A 2 datasets

ChIP K562 ENCFF514URW 405 bp overlap

ChIP spleen ENCFF446ZGT 129 bp overlap

POLR2G 1 dataset

ChIP HepG2 ENCFF508UTS 614 bp overlap

POU2F1 1 dataset

ChIP HepG2 ENCFF422JZU 190 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 102 bp overlap

PRDM10 1 dataset

ChIP Hep-G2 ENCSR289PSX.PRDM10.Hep-G2 139 bp overlap

RCOR1 1 dataset

ChIP K562 ENCFF216EEJ 297 bp overlap

ChIP K-562 ENCSR000BMW.REST.K-562 190 bp overlap

RUNX1 6 datasets

ChIP Jurkat GSE68976.RUNX1.Jurkat 492 bp overlap

ChIP Jurkat GSE76181.RUNX1.Jurkat 402 bp overlap

ChIP Jurkat GSE29180.RUNX1.Jurkat 179 bp overlap

ChIP ME-1_CBFB-MYH11-KD GSE117138.RUNX1.ME-1_CBFB-MYH11-KD 267 bp overlap

ChIP ME-1_Con GSE128771.RUNX1.ME-1_Con 267 bp overlap

ChIP epididymis_HEE GSE109061.RUNX1.epididymis_HEE 144 bp overlap

RUNX2 1 dataset

ChIP PER-117 GSE151819.RUNX2.PER-117 387 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 532 bp overlap

ChIP HUVEC-C_TGFB1 GSE134556.SMAD2-3.HUVEC-C_TGFB1 614 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 614 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 376 bp overlap

SMARCE1 1 dataset

ChIP K-562 ENCSR157TCS.SMARCE1.K-562 260 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 276 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 433 bp overlap

SOX6 2 datasets

ChIP K-562 ENCSR788RSW.SOX6.K-562 232 bp overlap

ChIP K562 ENCFF059YCJ 437 bp overlap

STAT1 1 dataset

ChIP SET-2_DMSO GSE100566.STAT1.SET-2_DMSO 168 bp overlap

STAT1_pS727 1 dataset

ChIP SET-2 GSE100566.STAT1_pS727.SET-2 93 bp overlap

STAT5A 2 datasets

ChIP K-562 ENCSR000BRR.STAT5A.K-562 178 bp overlap

ChIP K562 ENCFF226BTJ 341 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 212 bp overlap

TAL1 19 datasets

ChIP CCRF-CEM GSE33850.TAL1.CCRF-CEM 381 bp overlap

ChIP CD34 GSE52924.TAL1.CD34 184 bp overlap

ChIP HSPC-CD34pos GSE93372.TAL1.HSPC-CD34pos 151 bp overlap

ChIP Jurkat GSE29180.TAL1.Jurkat 375 bp overlap

ChIP K-562 GSE107726.TAL1.K-562 440 bp overlap

ChIP K-562 ENCSR106FRG.TAL1.K-562 433 bp overlap

ChIP K-562 ENCSR000EHB.TAL1.K-562 298 bp overlap

ChIP K-562_MYO1D-Hub_KO GSE107726.TAL1.K-562_MYO1D-Hub_KO 316 bp overlap

ChIP K-562_MYO1D-Non-hub_KO GSE107726.TAL1.K-562_MYO1D-Non-hub_KO 280 bp overlap

ChIP K-562_dCas9-KRAB GSE132212.TAL1.K-562_dCas9-KRAB 295 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.TAL1.K-562_dCas9-LSD1 294 bp overlap

ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 302 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 312 bp overlap

ChIP K-562_sgGal4 GSE132212.TAL1.K-562_sgGal4 295 bp overlap

ChIP K562 ENCFF620GMX 326 bp overlap

ChIP K562 ENCFF661CCK 164 bp overlap

ChIP MOLT-3 GSE59657.TAL1.MOLT-3 438 bp overlap

ChIP PRIMA2 GSE33850.TAL1.PRIMA2 289 bp overlap

ChIP ProEs GSE59087.TAL1.ProEs 318 bp overlap

TAL1_SCL 1 dataset

ChIP erythroid GSE25000.TAL1_SCL.erythroid 520 bp overlap

TCF12 5 datasets

ChIP Jurkat GSE29180.TCF12.Jurkat 252 bp overlap

ChIP K-562 ENCSR744WOO.TCF12.K-562 435 bp overlap

ChIP K-562 ENCSR189TRZ.TCF12.K-562 278 bp overlap

ChIP K562 ENCFF909RDY 397 bp overlap

ChIP K562 ENCFF931DJY 329 bp overlap

TCF3 2 datasets

ChIP K-562 ENCSR970OJY.TCF3.K-562 309 bp overlap

ChIP K562 ENCFF319QZT 157 bp overlap

TEAD4 1 dataset

ChIP K562 ENCFF673NIK 288 bp overlap

TFAP4 1 dataset

ChIP K562 ENCFF727PXG 433 bp overlap

TRIM24 2 datasets

ChIP K-562 ENCSR907MZR.TRIM24.K-562 233 bp overlap

ChIP K562 ENCFF616RIL 431 bp overlap

TRIM25 1 dataset

ChIP MDA-MB-231 GSE79588.TRIM25.MDA-MB-231 96 bp overlap

TRIM28 1 dataset

ChIP K-562 ENCSR000BRW.TRIM28.K-562 142 bp overlap

ChIP K-562 ENCSR000EFZ.UBTF.K-562 112 bp overlap

VEZF1 1 dataset

ChIP K562 ENCFF053XDV 614 bp overlap

ZBTB7A 1 dataset

ChIP K-562 ENCSR000BME.ZBTB7A.K-562 115 bp overlap

ZEB2 3 datasets

ChIP K-562 ENCSR004GKA.ZEB2.K-562 321 bp overlap

ChIP K562 ENCFF795CMH 477 bp overlap

ChIP K562 ENCFF975RXS 461 bp overlap

ZFP91 1 dataset

ChIP HepG2 ENCFF012CME 290 bp overlap

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 335 bp overlap

ZKSCAN1 1 dataset

ChIP K-562 ENCSR882ERE.ZKSCAN1.K-562 242 bp overlap

ZNF143 2 datasets

ChIP FLP76_T4 GSE39263.ZNF143.FLP76_T4 152 bp overlap

ChIP FLP76_T4 GSE39263.ZNF143.FLP76_T4 122 bp overlap

ZNF429 1 dataset

ChIP HEK293T GSE78099.ZNF429.HEK293T 195 bp overlap