chr15 : 76,339,679 – 76,340,052
373 bp 92 TFs 2 linked genes
This 373 bp open chromatin element is linked to ENSG00000259514 and ISL2 and is bound by 92 transcription factors.
Linked Genes
2 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ENSG00000259514 2.0 kb Proximal Proximity
ISL2 2.9 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr15:76,334,679 – 76,345,052
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
92 transcription factors
Source
Cell type
AFF1 2 datasets
ChIP SEM_CX4945 GSE90762.AFF1.SEM_CX4945 134 bp overlap
ChIP SEM_DMSO GSE90762.AFF1.SEM_DMSO 92 bp overlap
AGO1 3 datasets
ChIP Hep-G2 ENCSR555ZMV.AGO1.Hep-G2 189 bp overlap
ChIP Hep-G2 GSE120104.AGO1.Hep-G2 118 bp overlap
ChIP K562 ENCFF025NLP 81 bp overlap
AR 2 datasets
ChIP prostate_cancer-associated-fibroblasts GSE90772.AR.prostate_cancer-associated-fibroblasts 321 bp overlap
ChIP prostate_fetal-fibroblast GSE90772.AR.prostate_fetal-fibroblast 355 bp overlap
ASH2L 3 datasets
ChIP GM12878 ENCSR849WCQ.ASH2L.GM12878 128 bp overlap
ChIP WA01 ENCSR850KIP.ASH2L.WA01 103 bp overlap
ChIP WA01 ENCSR850KIP.ASH2L.WA01 159 bp overlap
BCOR 2 datasets
ChIP WA01_KDM2B_KO GSE104690.BCOR.WA01_KDM2B_KO 159 bp overlap
ChIP WA01_KDM2B_KO GSE104690.BCOR.WA01_KDM2B_KO 52 bp overlap
BMI1 2 datasets
ChIP GM12878 ENCSR469WII.BMI1.GM12878 373 bp overlap
ChIP MCF-7 ENCSR966YYJ.BMI1.MCF-7 351 bp overlap
BMPR1A 1 dataset
ChIP HUVEC-C GSE60156.BMPR1A.HUVEC-C 219 bp overlap
BRD1 1 dataset
ChIP HUES-64 GSE104059.BRD1.HUES-64 373 bp overlap
BRD4 16 datasets
ChIP CLL_patient1_4h_CpG GSE109411.BRD4.CLL_patient1_4h_CpG 142 bp overlap
ChIP CLL_patient1_4h_CpG_BET GSE109411.BRD4.CLL_patient1_4h_CpG_BET 373 bp overlap
ChIP CLL_patient2 GSE109411.BRD4.CLL_patient2 373 bp overlap
ChIP CLL_patient2_4h_CpG_BET GSE109411.BRD4.CLL_patient2_4h_CpG_BET 233 bp overlap
ChIP CLL_patient3 GSE109411.BRD4.CLL_patient3 270 bp overlap
ChIP CLL_patient3_4h_CpG GSE109411.BRD4.CLL_patient3_4h_CpG 295 bp overlap
ChIP CLL_patient3_4h_CpG_BET GSE109411.BRD4.CLL_patient3_4h_CpG_BET 373 bp overlap
ChIP CLL_patient4 GSE109411.BRD4.CLL_patient4 320 bp overlap
ChIP CLL_patient4_4h_CpG GSE109411.BRD4.CLL_patient4_4h_CpG 373 bp overlap
ChIP CLL_patient4_4h_CpG_BET GSE109411.BRD4.CLL_patient4_4h_CpG_BET 296 bp overlap
ChIP COLO-741 GSE73319.BRD4.COLO-741 235 bp overlap
ChIP HAP1 GSE108387.BRD4.HAP1 237 bp overlap
ChIP OCI-AML3 GSE104745.BRD4.OCI-AML3 118 bp overlap
ChIP OCI-AML3 GSE104745.BRD4.OCI-AML3 150 bp overlap
ChIP SK-N-BE2-C_Naive-veh GSE107706.BRD4.SK-N-BE2-C_Naive-veh 62 bp overlap
ChIP SK-N-BE2-C_Naive-veh GSE107706.BRD4.SK-N-BE2-C_Naive-veh 176 bp overlap
CBX4 1 dataset
ChIP hMSC GSE117084.CBX4.hMSC 329 bp overlap
CBX7 1 dataset
ChIP lymphocyte_UNC4976 GSE110139.CBX7.lymphocyte_UNC4976 90 bp overlap
CBX8 1 dataset
ChIP H1 ENCFF095JHA 221 bp overlap
CHD1 4 datasets
ChIP H1 ENCFF998XEK 237 bp overlap
ChIP H1 ENCFF998XEK 359 bp overlap
ChIP WA01 ENCSR000AQK.CHD1.WA01 127 bp overlap
ChIP WA01 ENCSR000AQK.CHD1.WA01 171 bp overlap
CTBP2 1 dataset
ChIP WA01 ENCSR000EUO.CTBP2.WA01 373 bp overlap
CTCF 3 datasets
ChIP MM1-S GSE43743.CTCF.MM1-S 84 bp overlap
ChIP T-47D_Y537S GSE148277.CTCF.T-47D_Y537S 373 bp overlap
ChIP neural ENCSR822CEA.CTCF.neural 197 bp overlap
Cebpa 2 datasets
ChIP BLaER1 ENCFF274GAT 309 bp overlap
ChIP BLaER1 ENCFF335XTP 177 bp overlap
E2F6 1 dataset
ChIP WA01 ENCSR000BSI.E2F6.WA01 291 bp overlap
EED 1 dataset
ChIP ProEs GSE59087.EED.ProEs 161 bp overlap
EGR1 1 dataset
ChIP A-375 GSE116190.EGR1.A-375 333 bp overlap
ELF1 1 dataset
ChIP GM12878 ENCSR000BMB.ELF1.GM12878 127 bp overlap
ERG 5 datasets
ChIP ME-1 GSE46044.ERG.ME-1 118 bp overlap
ChIP SEM GSE117864.ERG.SEM 373 bp overlap
ChIP SKNO-1 GSE23730.ERG.SKNO-1 373 bp overlap
ChIP TSU-1621MT GSE60477.ERG.TSU-1621MT 159 bp overlap
ChIP TSU-1621MT_ATRA GSE60477.ERG.TSU-1621MT_ATRA 119 bp overlap
ESR1 5 datasets
ChIP MCF-7_PaPE-1_OA GSE93510.ESR1.MCF-7_PaPE-1_OA 102 bp overlap
ChIP MCF-7_Veh GSE93510.ESR1.MCF-7_Veh 262 bp overlap
ChIP T-47D_D538G_E2 GSE148277.ESR1.T-47D_D538G_E2 148 bp overlap
ChIP T-47D_Y537S GSE148277.ESR1.T-47D_Y537S 373 bp overlap
ChIP T-47D_Y537S_E2 GSE148277.ESR1.T-47D_Y537S_E2 168 bp overlap
ETS1 2 datasets
ChIP HUVEC-C_VEGF_12H GSE41166.ETS1.HUVEC-C_VEGF_12H 54 bp overlap
ChIP cardiomyocyte_D0 GSE129986.ETS1.cardiomyocyte_D0 270 bp overlap
EZH2 22 datasets
ChIP B cell ENCFF803EMO 324 bp overlap
ChIP B cell ENCFF803EMO 122 bp overlap
ChIP DND41 ENCSR000ASW.EZH2.DND41 236 bp overlap
ChIP GM23248 ENCFF404ZHM 373 bp overlap
ChIP GM23338 ENCFF613YON 373 bp overlap
ChIP GM23338 ENCFF886DXX 115 bp overlap
ChIP GM23338 ENCFF886DXX 300 bp overlap
ChIP H1 ENCFF232NZA 373 bp overlap
ChIP astrocyte ENCFF365JTP 373 bp overlap
ChIP endothelial cell of umbilical vein ENCFF539AKL 373 bp overlap
ChIP fibroblast of dermis ENCFF029VZK 373 bp overlap
ChIP fibroblast of lung ENCFF479BAW 254 bp overlap
ChIP hESC GSE113817.EZH2.hESC 239 bp overlap
ChIP hESC_KO GSE113817.EZH2.hESC_KO 97 bp overlap
ChIP hepatocyte ENCFF552DZB 373 bp overlap
ChIP mammary epithelial cell ENCFF224GAI 373 bp overlap
ChIP neural cell ENCFF610EPB 57 bp overlap
ChIP neural cell ENCFF610EPB 373 bp overlap
ChIP neural progenitor cell ENCFF018MKA 373 bp overlap
ChIP neural progenitor cell ENCFF472NFV 373 bp overlap
ChIP peripheral-blood-mononuclear-cell_B-cell GSE115772.EZH2.peripheral-blood-mononuclear-cell_B-cell 187 bp overlap
ChIP peripheral-blood-mononuclear-cell_mut GSE115772.EZH2.peripheral-blood-mononuclear-cell_mut 102 bp overlap
EZH2_phosphoT487 1 dataset
ChIP GM23248 ENCSR096KPA.EZH2_phosphoT487.GM23248 373 bp overlap
FIP1L1 2 datasets
ChIP K562 ENCFF002WKI 85 bp overlap
ChIP K562 ENCFF363ZMN 88 bp overlap
FLI1 1 dataset
ChIP SKNO-1 GSE23730.FLI1.SKNO-1 373 bp overlap
GABPA 1 dataset
ChIP WA01 ENCSR000BIW.GABPA.WA01 152 bp overlap
GABPB1 1 dataset
ChIP HepG2 ENCFF315AWN 261 bp overlap
GTF2F1 1 dataset
ChIP K-562 GSE120104.GTF2F1.K-562 125 bp overlap
HCFC1R1 1 dataset
ChIP cartilage GSE100311.HCFC1R1.cartilage 351 bp overlap
HEXIM1 2 datasets
ChIP HCT-116 GSE72622.HEXIM1.HCT-116 59 bp overlap
ChIP HCT-116 GSE72622.HEXIM1.HCT-116 134 bp overlap
HIVEP1 1 dataset
ChIP Hep-G2 ENCSR697WMX.HIVEP1.Hep-G2 348 bp overlap
HNRNPLL 3 datasets
ChIP Hep-G2 ENCSR804HMZ.HNRNPLL.Hep-G2 373 bp overlap
ChIP Hep-G2 GSE120104.HNRNPLL.Hep-G2 362 bp overlap
ChIP HepG2 ENCFF952XAB 284 bp overlap
IRF4 1 dataset
ChIP T-cell GSE136853.IRF4.T-cell 77 bp overlap
JUN 3 datasets
ChIP 786-O GSE86092.JUN.786-O 163 bp overlap
ChIP ESC S24-ESC-d0-JUN-exp1 217 bp overlap
ChIP HUES-8 GSE109524.JUN.HUES-8 373 bp overlap
KDM4A 2 datasets
ChIP H1 ENCFF078LED 373 bp overlap
ChIP WA01 ENCSR000AVC.KDM4A.WA01 185 bp overlap
KDM5B 2 datasets
ChIP SUM185 GSE46055.KDM5B.SUM185 126 bp overlap
ChIP SUM185_SHCTCF GSE46055.KDM5B.SUM185_SHCTCF 265 bp overlap
KMT2A 5 datasets
ChIP HEK293T_N-term_C104 GSE90762.KMT2A.HEK293T_N-term_C104 50 bp overlap
ChIP KOPN-8 GSE83671.KMT2A.KOPN-8 259 bp overlap
ChIP RCH-ACV GSE83671.KMT2A.RCH-ACV 248 bp overlap
ChIP RS4-11_DMSO-D3-180402 GSE127507.KMT2A.RS4-11_DMSO-D3-180402 138 bp overlap
ChIP blood_cord GSE83671.KMT2A.blood_cord 259 bp overlap
MAX 1 dataset
ChIP NCI-H2171 GSE41105.MAX.NCI-H2171 52 bp overlap
MEN1 1 dataset
ChIP RS4-11_DMSO-D3-180110 GSE127507.MEN1.RS4-11_DMSO-D3-180110 77 bp overlap
MLLT3 1 dataset
ChIP HSPC_MLLT3-virus GSE111482.MLLT3.HSPC_MLLT3-virus 373 bp overlap
MYBL2 1 dataset
ChIP A-673 GSE119971.MYBL2.A-673 191 bp overlap
MYC 4 datasets
ChIP BJ_INDUCED GSE36570.MYC.BJ_INDUCED 144 bp overlap
ChIP NB69 GSE138295.MYC.NB69 165 bp overlap
ChIP P493-6_Dpy30-shRNA GSE101853.MYC.P493-6_Dpy30-shRNA 93 bp overlap
ChIP P493-6_scramble-shRNA GSE101853.MYC.P493-6_scramble-shRNA 269 bp overlap
NANOG 1 dataset
ChIP HUES-8 GSE109524.NANOG.HUES-8 373 bp overlap
NELFE 1 dataset
ChIP K-562_NHS GSE112379.NELFE.K-562_NHS 137 bp overlap
NFE2L2 1 dataset
ChIP A-549 GSE113497.NFE2L2.A-549 249 bp overlap
NUTM1 1 dataset
ChIP embryonic-kidney_induced GSE133122.NUTM1.embryonic-kidney_induced 373 bp overlap
OGG1 4 datasets
ChIP HEK293 GSE89017.OGG1.HEK293 222 bp overlap
ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 209 bp overlap
ChIP HEK293_30_min GSE89017.OGG1.HEK293_30_min 75 bp overlap
ChIP HEK293_60_min GSE89017.OGG1.HEK293_60_min 137 bp overlap
PAX6 1 dataset
ChIP retina_pigment GSE60024.PAX6.retina_pigment 109 bp overlap
PCGF2 1 dataset
ChIP NT2-D1 GSE101538.PCGF2.NT2-D1 373 bp overlap
PHF19 1 dataset
ChIP DU145_CTR GSE135623.PHF19.DU145_CTR 289 bp overlap
PHF8 1 dataset
ChIP Hep-G2 ENCSR604VAE.PHF8.Hep-G2 126 bp overlap
POLR2A 5 datasets
ChIP endothelial cell of umbilical vein ENCFF303XUJ 100 bp overlap
ChIP neural cell ENCFF604SPB 111 bp overlap
ChIP neural cell ENCFF604SPB 111 bp overlap
ChIP spleen ENCFF446ZGT 120 bp overlap
ChIP spleen ENCFF706IUS 370 bp overlap
POLR2G 1 dataset
ChIP K562 ENCFF648YPL 209 bp overlap
POU2F1 1 dataset
ChIP T-47D_D538G GSE148277.POU2F1.T-47D_D538G 238 bp overlap
POU5F1 4 datasets
ChIP DE_D1 DED1-OCT4_Batch_II 373 bp overlap
ChIP HUES-8 GSE109524.POU5F1.HUES-8 373 bp overlap
ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 296 bp overlap
ChIP SKM-1 GSE93706.POU5F1.SKM-1 357 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 373 bp overlap
PRDM14 1 dataset
ChIP NCCIT GSE71675.PRDM14.NCCIT 54 bp overlap
PRPF4 1 dataset
ChIP K562 ENCFF046WLD 364 bp overlap
PTBP1 2 datasets
ChIP Hep-G2 ENCSR156APP.PTBP1.Hep-G2 149 bp overlap
ChIP Hep-G2 GSE120104.PTBP1.Hep-G2 128 bp overlap
RBBP5 1 dataset
ChIP WA01 ENCSR000AQC.RBBP5.WA01 185 bp overlap
RBFOX2 2 datasets
ChIP K562 ENCFF196WTG 373 bp overlap
ChIP K562 ENCFF967GRF 373 bp overlap
RBM22 1 dataset
ChIP K-562 GSE120104.RBM22.K-562 134 bp overlap
RELA 3 datasets
ChIP HEK293_TNF-1h GSE75562.RELA.HEK293_TNF-1h 102 bp overlap
ChIP HEK293_TNF-30min GSE75562.RELA.HEK293_TNF-30min 145 bp overlap
ChIP SGBS GSE64233.RELA.SGBS 272 bp overlap
REST 1 dataset
ChIP PANC-1 ENCSR000BJO.REST.PANC-1 87 bp overlap
RNF2 3 datasets
ChIP H1 ENCFF239FFS 373 bp overlap
ChIP SYO-1_shCt GSE139053.RNF2.SYO-1_shCt 315 bp overlap
ChIP SYO-1_shRING1A-B GSE139053.RNF2.SYO-1_shRING1A-B 178 bp overlap
RORC 1 dataset
ChIP HCC70_XY018 GSE126380.RORC.HCC70_XY018 170 bp overlap
RUNX1T1 1 dataset
ChIP Kasumi-1 GSE115115.RUNX1T1.Kasumi-1 74 bp overlap
SALL3 1 dataset
ChIP hiPSC GSE104863.SALL3.hiPSC 351 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8 GSE109524.SMAD2-3.HUES-8 373 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 289 bp overlap
SMAD2_3 2 datasets
ChIP ESC S23-ESC-d0-SMAD2_3-exp1 348 bp overlap
ChIP ESC S33-ESC-d0-SMAD2_3-exp2 373 bp overlap
SMARCA4 1 dataset
ChIP Aska-SS GSE108025.SMARCA4.Aska-SS 280 bp overlap
SMC1 3 datasets
ChIP HCAEC GSE101921.SMC1.HCAEC 370 bp overlap
ChIP IMR-90_OIS GSE118494.SMC1.IMR-90_OIS 52 bp overlap
ChIP IMR-90_OIS GSE118494.SMC1.IMR-90_OIS 221 bp overlap
SNAI2 2 datasets
ChIP PC-9_1DF GSE131687.SNAI2.PC-9_1DF 206 bp overlap
ChIP PC-9_2DF_DMSO GSE131687.SNAI2.PC-9_2DF_DMSO 76 bp overlap
SPI1 2 datasets
ChIP primary-monocyte_18h_donorO GSE128834.SPI1.primary-monocyte_18h_donorO 112 bp overlap
ChIP primary-neutrophil_donorE GSE128834.SPI1.primary-neutrophil_donorE 97 bp overlap
SRSF3 1 dataset
ChIP K-562 GSE120104.SRSF3.K-562 373 bp overlap
SS18 3 datasets
ChIP Aska-SS GSE108025.SS18.Aska-SS 65 bp overlap
ChIP Aska-SS GSE108025.SS18.Aska-SS 163 bp overlap
ChIP Aska-SS_BAF47KO1 GSE108025.SS18.Aska-SS_BAF47KO1 373 bp overlap
STAG2 1 dataset
ChIP OCI-AML-3 GSE111537.STAG2.OCI-AML-3 117 bp overlap
SUZ12 5 datasets
ChIP H1 ENCFF507HGF 271 bp overlap
ChIP H1 ENCFF881NFR 373 bp overlap
ChIP MCF-7 ENCSR757EMK.SUZ12.MCF-7 199 bp overlap
ChIP NT2-D1 GSE101538.SUZ12.NT2-D1 338 bp overlap
ChIP NT2/D1 ENCFF574SXS 373 bp overlap
TARDBP 2 datasets
ChIP K-562 ENCSR429XTR.TARDBP.K-562 144 bp overlap
ChIP K-562 GSE120104.TARDBP.K-562 52 bp overlap
TCF12 2 datasets
ChIP WA01 ENCSR000BIT.TCF12.WA01 188 bp overlap
ChIP WA01 ENCSR000BIT.TCF12.WA01 55 bp overlap
TCF7L2 1 dataset
ChIP CD34_PROG_BIO GSE29194.TCF7L2.CD34_PROG_BIO 373 bp overlap
TERF1 1 dataset
ChIP LCL GSE55053.TERF1.LCL 194 bp overlap
TP63 1 dataset
ChIP keratinocyte_diff GSE33571.TP63.keratinocyte_diff 104 bp overlap
TRIM28 1 dataset
ChIP AF22 GSE84259.TRIM28.AF22 373 bp overlap
ZBTB48 1 dataset
ChIP U2OS GSE96776.ZBTB48.U2OS 325 bp overlap
ZFX 2 datasets
ChIP HEK293T_22Rv1 GSE145160.ZFX.HEK293T_22Rv1 130 bp overlap
ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 373 bp overlap
ZNF263 2 datasets
ChIP K-562 ENCSR000EWN.ZNF263.K-562 124 bp overlap
ChIP K-562 ENCSR000EWN.ZNF263.K-562 81 bp overlap
ZNF274 1 dataset
ChIP Hep-G2 ENCSR871VNN.ZNF274.Hep-G2 108 bp overlap
ZNF512 2 datasets
ChIP WTC11 ENCFF086TTM 93 bp overlap
ChIP WTC11 ENCFF086TTM 292 bp overlap
ZNF784 1 dataset
ChIP HepG2 ENCFF265UCH 153 bp overlap
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