chr12 : 57,237,027 – 57,237,584
557 bp 93 TFs 3 linked genes
This 557 bp open chromatin element is linked to NDUFA4L2, ENSG00000276727, and SHMT2 and is bound by 93 transcription factors.
Linked Genes
3 genes
Distance
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
NDUFA4L2 at TSS At TSS Proximity
ENSG00000276727 6.8 kb Proximal Proximity
SHMT2 7.3 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr12:57,232,027 – 57,242,584
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
93 transcription factors
Source
Cell type
AKAP8 2 datasets
ChIP HepG2 ENCFF478OVI 526 bp overlap
ChIP HepG2 ENCFF478OVI 327 bp overlap
ARID2 1 dataset
ChIP Aska-SS GSE108025.ARID2.Aska-SS 557 bp overlap
ASH2L 1 dataset
ChIP WA01 ENCSR850KIP.ASH2L.WA01 310 bp overlap
BCL6 1 dataset
ChIP CD4 GSE59933.BCL6.CD4 135 bp overlap
BRD4 3 datasets
ChIP CLL_patient2_4h_CpG_BET GSE109411.BRD4.CLL_patient2_4h_CpG_BET 196 bp overlap
ChIP retina_AB1-FW23 GSE86981.BRD4.retina_AB1-FW23 254 bp overlap
ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 248 bp overlap
CTCF 2 datasets
ChIP T-47D_D538G GSE148277.CTCF.T-47D_D538G 141 bp overlap
ChIP keratinocyte GSE154221.CTCF.keratinocyte 276 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF262VBH 257 bp overlap
DEK 2 datasets
ChIP HeLa-S3 ENCSR219MKK.DEK.HeLa-S3 228 bp overlap
ChIP HeLa-S3 ENCSR219MKK.DEK.HeLa-S3 283 bp overlap
EGR1 1 dataset
ChIP Hep-G2 ENCSR026GSW.EGR1.Hep-G2 189 bp overlap
ELF1 2 datasets
ChIP GM12878 ENCFF432UGA 258 bp overlap
ChIP GM12878 ENCSR000BMB.ELF1.GM12878 199 bp overlap
ESR1 2 datasets
ChIP MCF-7_RUNX2_DOX GSE86538.ESR1.MCF-7_RUNX2_DOX 83 bp overlap
ChIP T-47D_Y537S GSE148277.ESR1.T-47D_Y537S 254 bp overlap
EZH2 7 datasets
ChIP B-cell ENCSR000AUZ.EZH2.B-cell 209 bp overlap
ChIP GM23338 ENCFF613YON 267 bp overlap
ChIP Karpas-422_CPI360-D8 GSE134136.EZH2.Karpas-422_CPI360-D8 238 bp overlap
ChIP SF8628 GSE94834.EZH2.SF8628 301 bp overlap
ChIP endothelial cell of umbilical vein ENCFF539AKL 409 bp overlap
ChIP neural progenitor cell ENCFF472NFV 202 bp overlap
ChIP peripheral-blood-mononuclear-cell_B-cell GSE115772.EZH2.peripheral-blood-mononuclear-cell_B-cell 231 bp overlap
FIP1L1 1 dataset
ChIP Hep-G2 ENCSR313VZG.FIP1L1.Hep-G2 191 bp overlap
HDAC2 1 dataset
ChIP K-562 ENCSR893WSB.HDAC2.K-562 313 bp overlap
HDGF 1 dataset
ChIP K-562 ENCSR563YDA.HDGF.K-562 338 bp overlap
HNF4A 1 dataset
ChIP IM95 GSE114018.HNF4A.IM95 152 bp overlap
HNRNPH1 4 datasets
ChIP Hep-G2 ENCSR066FXN.HNRNPH1.Hep-G2 136 bp overlap
ChIP Hep-G2 GSE120104.HNRNPH1.Hep-G2 109 bp overlap
ChIP Hep-G2 ENCSR066FXN.HNRNPH1.Hep-G2 186 bp overlap
ChIP Hep-G2 GSE120104.HNRNPH1.Hep-G2 376 bp overlap
HNRNPK 1 dataset
ChIP Hep-G2 GSE120104.HNRNPK.Hep-G2 60 bp overlap
HNRNPLL 1 dataset
ChIP K-562 ENCSR112RNT.HNRNPLL.K-562 82 bp overlap
IKZF1 1 dataset
ChIP K-562 ENCSR395HWC.IKZF1.K-562 467 bp overlap
IKZF3 1 dataset
ChIP HEK293 ENCSR304AMN.IKZF3.HEK293 557 bp overlap
IRF4 1 dataset
ChIP U266 GSE142493.IRF4.U266 247 bp overlap
JARID2 1 dataset
ChIP UTEIPS11 GSE48516.JARID2.UTEIPS11 233 bp overlap
JUN 1 dataset
ChIP 786-O GSE86092.JUN.786-O 203 bp overlap
JUND 1 dataset
ChIP HT29_DSMO GSE77039.JUND.HT29_DSMO 204 bp overlap
KLF1 3 datasets
ChIP HEK293 ENCFF159QSW 277 bp overlap
ChIP HEK293 ENCSR859BMR.KLF1.HEK293 412 bp overlap
ChIP HEK293 GSE76494.KLF1.HEK293 174 bp overlap
KLF17 1 dataset
ChIP HEK293 ENCSR065WUF.KLF17.HEK293 240 bp overlap
KLF3 1 dataset
ChIP keratinocyte GSE140991.KLF3.keratinocyte 254 bp overlap
KMT2A 2 datasets
ChIP IMS-M2_DMSO GSE129636.KMT2A.IMS-M2_DMSO 197 bp overlap
ChIP MOLM-13_VTP-d3-180110 GSE127507.KMT2A.MOLM-13_VTP-d3-180110 128 bp overlap
MAF 1 dataset
ChIP CD4_Th1 GSE72266.MAF.CD4_Th1 557 bp overlap
MAX 4 datasets
ChIP Ishikawa ENCFF064TDQ 152 bp overlap
ChIP Ishikawa ENCFF064TDQ 461 bp overlap
ChIP K562 ENCFF524IJO 280 bp overlap
ChIP NCI-H2171 GSE36354.MAX.NCI-H2171 221 bp overlap
MAZ 4 datasets
ChIP HEK293 ENCFF994GSG 181 bp overlap
ChIP HEK293 ENCSR290SSQ.MAZ.HEK293 557 bp overlap
ChIP HEK293 GSE76494.MAZ.HEK293 223 bp overlap
ChIP K-562 ENCSR000EFX.MAZ.K-562 148 bp overlap
MED1 1 dataset
ChIP NCI-H2171 GSE36354.MED1.NCI-H2171 250 bp overlap
MORC2 1 dataset
ChIP HeLa_V5-MORC2-KO-W505A-MORC2-mut GSE95451.MORC2.HeLa_V5-MORC2-KO-W505A-MORC2-mut 255 bp overlap
MYCN 1 dataset
ChIP COG-N-415 GSE138295.MYCN.COG-N-415 420 bp overlap
MYF5 1 dataset
ChIP Rh18 GSE84628.MYF5.Rh18 304 bp overlap
MYNN 1 dataset
ChIP Hep-G2 ENCSR398TMP.MYNN.Hep-G2 151 bp overlap
NCAPH2 1 dataset
ChIP IMR-90_FLAG_OIS GSE118494.NCAPH2.IMR-90_FLAG_OIS 388 bp overlap
NELFE 2 datasets
ChIP K-562_NHS GSE112379.NELFE.K-562_NHS 91 bp overlap
ChIP K-562_NHS GSE112379.NELFE.K-562_NHS 155 bp overlap
NEUROD1 1 dataset
ChIP D283-Med GSE92582.NEUROD1.D283-Med 514 bp overlap
NR1H2 2 datasets
ChIP HT29_GW3965_2H GSE77039.NR1H2.HT29_GW3965_2H 278 bp overlap
ChIP HT29_GW3965_48H GSE77039.NR1H2.HT29_GW3965_48H 479 bp overlap
PATZ1 1 dataset
ChIP HEK293 ENCFF016MNJ 258 bp overlap
PCBP2 1 dataset
ChIP Hep-G2 GSE120104.PCBP2.Hep-G2 127 bp overlap
POLR2A 9 datasets
ChIP HeLa-S3 ENCFF045HUU 514 bp overlap
ChIP HeLa-S3 ENCFF045HUU 304 bp overlap
ChIP HeLa-S3 ENCFF455YYQ 496 bp overlap
ChIP HeLa-S3 ENCFF773DNG 464 bp overlap
ChIP HeLa-S3 ENCFF773DNG 212 bp overlap
ChIP HepG2 ENCFF736SLT 422 bp overlap
ChIP Raji ENCFF613VGX 186 bp overlap
ChIP heart left ventricle ENCFF591JWH 353 bp overlap
ChIP spleen ENCFF446ZGT 276 bp overlap
POLR2G 2 datasets
ChIP HepG2 ENCFF241AEG 557 bp overlap
ChIP HepG2 ENCFF508UTS 557 bp overlap
POU5F1 1 dataset
ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 156 bp overlap
PRDM10 1 dataset
ChIP HEK293 ENCFF145WQQ 253 bp overlap
PRDM14 1 dataset
ChIP NCCIT GSE71675.PRDM14.NCCIT 248 bp overlap
PTBP1 1 dataset
ChIP Hep-G2 ENCSR156APP.PTBP1.Hep-G2 170 bp overlap
RBFOX2 2 datasets
ChIP K-562 ENCSR822LBD.RBFOX2.K-562 175 bp overlap
ChIP K-562 GSE120104.RBFOX2.K-562 175 bp overlap
RBM39 5 datasets
ChIP Hep-G2 ENCSR339JTP.RBM39.Hep-G2 156 bp overlap
ChIP Hep-G2 GSE120104.RBM39.Hep-G2 239 bp overlap
ChIP HepG2 ENCFF084YZE 431 bp overlap
ChIP HepG2 ENCFF084YZE 557 bp overlap
ChIP HepG2 ENCFF801JUH 419 bp overlap
REL 1 dataset
ChIP Ramos GSE139810.REL.Ramos 462 bp overlap
REST 27 datasets
ChIP A-549 ENCSR000BQP.REST.A-549 254 bp overlap
ChIP GM12878 ENCFF235NGC 169 bp overlap
ChIP GM12878 ENCSR000BGF.REST.GM12878 131 bp overlap
ChIP GM12878 ENCSR000BQS.REST.GM12878 85 bp overlap
ChIP GM23338 ENCFF024TCL 178 bp overlap
ChIP GM23338 ENCSR871KYB.REST.GM23338 111 bp overlap
ChIP H1 ENCFF429RUE 87 bp overlap
ChIP HEK293 ENCFF073DOT 281 bp overlap
ChIP HEK293 ENCSR896UBV.REST.HEK293 287 bp overlap
ChIP HL-60 ENCFF589LOF 241 bp overlap
ChIP HeLa-S3 ENCFF911DTC 172 bp overlap
ChIP HeLa-S3 ENCSR000BMN.REST.HeLa-S3 142 bp overlap
ChIP Ishikawa ENCFF456OHV 253 bp overlap
ChIP K-562 ENCSR000ATM.REST.K-562 240 bp overlap
ChIP K-562 ENCSR137ZMQ.REST.K-562 210 bp overlap
ChIP K-562 ENCSR000BMW.REST.K-562 183 bp overlap
ChIP K562 ENCFF430APM 103 bp overlap
ChIP K562 ENCFF688UKW 239 bp overlap
ChIP K562 ENCFF758CZL 449 bp overlap
ChIP K562 ENCFF758CZL 243 bp overlap
ChIP WA01 ENCSR000BHM.REST.WA01 173 bp overlap
ChIP colorectal-cancer_CRC121_intact GSE112555.REST.colorectal-cancer_CRC121_intact 283 bp overlap
ChIP colorectal-cancer_shCDH1 GSE112555.REST.colorectal-cancer_shCDH1 401 bp overlap
ChIP colorectal-cancer_shCTRL_dissociated GSE112555.REST.colorectal-cancer_shCTRL_dissociated 177 bp overlap
ChIP colorectal-cancer_shCTRL_intact GSE112555.REST.colorectal-cancer_shCTRL_intact 258 bp overlap
ChIP liver ENCFF240FWT 301 bp overlap
ChIP liver ENCSR893QWP.REST.liver 101 bp overlap
RNF2 5 datasets
ChIP H1 ENCFF239FFS 379 bp overlap
ChIP H1 ENCFF239FFS 557 bp overlap
ChIP WA01 ENCSR784VUY.RNF2.WA01 557 bp overlap
ChIP WA09_heat-shock GSE105028.RNF2.WA09_heat-shock 153 bp overlap
ChIP WA09_heat-shock GSE105028.RNF2.WA09_heat-shock 294 bp overlap
RPA2_phospho 3 datasets
ChIP HeLa GSE108172.RPA2_phospho.HeLa 118 bp overlap
ChIP HeLa_shASF GSE108172.RPA2_phospho.HeLa_shASF 264 bp overlap
ChIP HeLa_shTOP1 GSE108172.RPA2_phospho.HeLa_shTOP1 284 bp overlap
RUNX3 1 dataset
ChIP GM12878 ENCFF395WHA 83 bp overlap
RUVBL2 1 dataset
ChIP Huh-7 GSE97411.RUVBL2.Huh-7 408 bp overlap
SCRT2 1 dataset
ChIP HEK293 ENCFF711QQB 362 bp overlap
SIN3A 1 dataset
ChIP WA01 ENCSR000EBO.SIN3A.WA01 86 bp overlap
SMAD3 2 datasets
ChIP H69_4TGF GSE145250.SMAD3.H69_4TGF 186 bp overlap
ChIP H69_4TGF GSE145250.SMAD3.H69_4TGF 177 bp overlap
SMARCA4 2 datasets
ChIP Aska-SS_shSSX GSE108025.SMARCA4.Aska-SS_shSSX 164 bp overlap
ChIP J-Lat_GFP-Clone-A72_DMSO GSE100266.SMARCA4.J-Lat_GFP-Clone-A72_DMSO 460 bp overlap
SP1 1 dataset
ChIP Hep-G2 ENCSR460YAM.SP1.Hep-G2 123 bp overlap
SP2 3 datasets
ChIP HEK293 ENCFF181QXT 330 bp overlap
ChIP HEK293 ENCSR807LQP.SP2.HEK293 550 bp overlap
ChIP HEK293 GSE76494.SP2.HEK293 248 bp overlap
SP3 2 datasets
ChIP HEK293 ENCFF087XLA 404 bp overlap
ChIP HEK293 ENCSR141PZA.SP3.HEK293 296 bp overlap
SP4 1 dataset
ChIP HEK293 GSE76494.SP4.HEK293 191 bp overlap
SS18 1 dataset
ChIP Aska-SS GSE108025.SS18.Aska-SS 391 bp overlap
SUPT5H 5 datasets
ChIP DLD-1_NELFCD-AID_treated GSE144786.SUPT5H.DLD-1_NELFCD-AID_treated 372 bp overlap
ChIP HCT-116_DMSO GSE138548.SUPT5H.HCT-116_DMSO 284 bp overlap
ChIP HCT-116_pThr806 GSE138548.SUPT5H.HCT-116_pThr806 227 bp overlap
ChIP U2OS_siCtrl GSE115365.SUPT5H.U2OS_siCtrl 485 bp overlap
ChIP U2OS_siMYC GSE115365.SUPT5H.U2OS_siMYC 68 bp overlap
SUZ12 3 datasets
ChIP CRL-7250_shSS18 GSE108025.SUZ12.CRL-7250_shSS18 137 bp overlap
ChIP H1 ENCFF507HGF 168 bp overlap
ChIP Karpas-422_CPI360-D4 GSE134136.SUZ12.Karpas-422_CPI360-D4 284 bp overlap
TARDBP 1 dataset
ChIP K-562 GSE120104.TARDBP.K-562 148 bp overlap
TCF12 1 dataset
ChIP A-549 ENCSR000BQQ.TCF12.A-549 245 bp overlap
TCF21 1 dataset
ChIP HCASMC GSE124011.TCF21.HCASMC 259 bp overlap
TCF3 1 dataset
ChIP Kasumi-1 GSE43834.TCF3.Kasumi-1 188 bp overlap
TEAD4 1 dataset
ChIP SK-MEL-147 GSE94488.TEAD4.SK-MEL-147 132 bp overlap
TGIF2 2 datasets
ChIP WTC11 ENCFF649SHI 200 bp overlap
ChIP WTC11 ENCFF649SHI 410 bp overlap
XRCC5 1 dataset
ChIP K-562 GSE120104.XRCC5.K-562 330 bp overlap
ZBTB42 1 dataset
ChIP HEK293 GSE76494.ZBTB42.HEK293 182 bp overlap
ZBTB7A 2 datasets
ChIP Hep-G2 ENCSR000BQA.ZBTB7A.Hep-G2 109 bp overlap
ChIP K-562 ENCSR000BME.ZBTB7A.K-562 99 bp overlap
ZEB1 1 dataset
ChIP RKO GSE88734.ZEB1.RKO 99 bp overlap
ZEB2 2 datasets
ChIP HEK293 ENCFF847JIE 383 bp overlap
ChIP HEK293 ENCSR417VWF.ZEB2.HEK293 557 bp overlap
ZFP69B 1 dataset
ChIP HEK293 ENCSR381VYR.ZFP69B.HEK293 241 bp overlap
ZNF101 1 dataset
ChIP HEK293T GSE78099.ZNF101.HEK293T 107 bp overlap
ZNF121 1 dataset
ChIP HEK293 GSE76494.ZNF121.HEK293 175 bp overlap
ZNF143 1 dataset
ChIP K-562 ENCSR000EGP.ZNF143.K-562 108 bp overlap
ZNF257 1 dataset
ChIP HEK293T GSE78099.ZNF257.HEK293T 217 bp overlap
ZNF263 6 datasets
ChIP HEK293 ENCFF336CWQ 232 bp overlap
ChIP HEK293 ENCFF336CWQ 515 bp overlap
ChIP HEK293T GSE78099.ZNF263.HEK293T 179 bp overlap
ChIP Hep-G2 ENCSR313MMD.ZNF263.Hep-G2 255 bp overlap
ChIP K-562 ENCSR000EWN.ZNF263.K-562 112 bp overlap
ChIP K-562 ENCSR000EWN.ZNF263.K-562 321 bp overlap
ZNF3 1 dataset
ChIP K-562 ENCSR195QFV.ZNF3.K-562 246 bp overlap
ZNF335 3 datasets
ChIP HEK293 ENCFF784SLD 557 bp overlap
ChIP HEK293 ENCFF784SLD 557 bp overlap
ChIP HEK293 ENCSR328SUD.ZNF335.HEK293 557 bp overlap
ZNF467 1 dataset
ChIP HEK293 GSE76494.ZNF467.HEK293 268 bp overlap
ZNF534 1 dataset
ChIP HEK293T GSE78099.ZNF534.HEK293T 143 bp overlap
ZNF554 1 dataset
ChIP HEK293 GSE76494.ZNF554.HEK293 141 bp overlap
ZNF600 1 dataset
ChIP HEK293 ENCFF785JSX 335 bp overlap
ZNF692 1 dataset
ChIP HEK293 ENCSR418MKG.ZNF692.HEK293 201 bp overlap
ZNF891 1 dataset
ChIP Hep-G2 ENCSR020CLV.ZNF891.Hep-G2 453 bp overlap
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