chr10:99,266,221–99,266,995

chr10 : 99,266,221 – 99,266,995

774 bp 113 TFs 5 linked genes

This 774 bp open chromatin element is linked to 5 target genes and is bound by 113 transcription factors.

Linked Genes

5 genes

Gene	Expression	Dist. to TSS	Distance	Link type
CNNM1		62.8 kb	Distal	Multiome
GOT1		164.0 kb	Distal	Multiome
HPSE2		522.5 kb	Distal	Multiome+HiCAR
HPS1		819.7 kb	Distal	Multiome+HiCAR
PYROXD2		851.4 kb	Distal	Multiome+HiCAR

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

113 transcription factors

ChIP LAPC-4_R1881 GSE148358.AR.LAPC-4_R1881 139 bp overlap

ChIP LNCaP GSE64656.AR.LNCaP 256 bp overlap

ChIP LNCaP GSE110655.AR.LNCaP 234 bp overlap

ChIP LNCaP ERP003503.AR.LNCaP 199 bp overlap

ChIP LNCaP ERP001226.AR.LNCaP 205 bp overlap

ChIP LNCaP-abl GSE39459.AR.LNCaP-abl 123 bp overlap

ChIP LNCaP-clone-FGC_DHT-ABBV-744 GSE118247.AR.LNCaP-clone-FGC_DHT-ABBV-744 226 bp overlap

ChIP LNCaP_DSG GSE114737.AR.LNCaP_DSG 229 bp overlap

ChIP LNCaP_FOXA1 ERP003503.AR.LNCaP_FOXA1 230 bp overlap

ChIP LNCaP_SHCTR_DHT GSE62492.AR.LNCaP_SHCTR_DHT 113 bp overlap

ChIP LNCaP_Talen_DHT GSE89938.AR.LNCaP_Talen_DHT 157 bp overlap

ChIP LNCaP_androgen-N_hypoxia-N GSE114732.AR.LNCaP_androgen-N_hypoxia-N 183 bp overlap

ChIP LNCaP_androgen-N_hypoxia-Y GSE114732.AR.LNCaP_androgen-N_hypoxia-Y 169 bp overlap

ChIP LNCaP_r1881 GSE94682.AR.LNCaP_r1881 255 bp overlap

ChIP LNCaP_sgCHD1 GSE117430.AR.LNCaP_sgCHD1 223 bp overlap

ChIP LTAD_siControl GSE94577.AR.LTAD_siControl 246 bp overlap

ChIP VCaP GSE148358.AR.VCaP 211 bp overlap

ChIP VCaP_DHT24H GSE58428.AR.VCaP_DHT24H 513 bp overlap

ChIP VCaP_DHT24H_SHFOXP1 GSE58428.AR.VCaP_DHT24H_SHFOXP1 533 bp overlap

ChIP VCaP_DHT24H_SHRUNX1 GSE58428.AR.VCaP_DHT24H_SHRUNX1 281 bp overlap

ChIP VCaP_Darolutamide GSE148358.AR.VCaP_Darolutamide 179 bp overlap

ChIP VCaP_R1881 GSE32892.AR.VCaP_R1881 164 bp overlap

ChIP prostate-cancer_C4-2-CON GSE136128.AR.prostate-cancer_C4-2-CON 178 bp overlap

ChIP prostate-cancer_PDX_136 GSE130408.AR.prostate-cancer_PDX_136 168 bp overlap

ChIP prostate-cancer_PDX_189-4 GSE130408.AR.prostate-cancer_PDX_189-4 141 bp overlap

ChIP prostate-cancer_PDX_78 GSE130408.AR.prostate-cancer_PDX_78 77 bp overlap

ChIP prostate-cancer_PDX_92 GSE130408.AR.prostate-cancer_PDX_92 96 bp overlap

ARID1A 1 dataset

ChIP HAP1 GSE108387.ARID1A.HAP1 359 bp overlap

ARNT2 1 dataset

Motif DE_72h DE_72h-ARNT2_MA1464.2 8 bp overlap

ARNT::HIF1A 1 dataset

Motif DE_72h DE_72h-ARNTHIF1A_MA0259.2 5 bp overlap

ASXL3 2 datasets

ChIP NCI-H1963_Ab1 GSE145028.ASXL3.NCI-H1963_Ab1 598 bp overlap

ChIP NCI-H1963_Ab2 GSE145028.ASXL3.NCI-H1963_Ab2 277 bp overlap

Ahr::Arnt 1 dataset

Motif DE_72h DE_72h-AhrArnt_MA0006.2 5 bp overlap

Motif DE_72h DE_72h-Arnt_MA0004.1 6 bp overlap

Arntl 1 dataset

Motif DE_72h DE_72h-Arntl_MA0603.2 8 bp overlap

BAP1 2 datasets

ChIP NCI-H1963_shASXL3 GSE145028.BAP1.NCI-H1963_shASXL3 774 bp overlap

ChIP NCI-H1963_shNONT GSE145028.BAP1.NCI-H1963_shNONT 774 bp overlap

BCL6B 2 datasets

ChIP HEK293 ENCFF555YRB 365 bp overlap

ChIP HEK293 ENCSR673SGK.BCL6B.HEK293 235 bp overlap

BHLHE22 1 dataset

Motif DE_72h DE_72h-BHLHE22_MA1635.2 6 bp overlap

BORCS8-MEF2B,MEF2B 1 dataset

ChIP GM12878 ENCFF427QAI 505 bp overlap

BRD3 2 datasets

ChIP HEK293T GSE39579.BRD3.HEK293T 132 bp overlap

ChIP HEK293T GSE39579.BRD3.HEK293T 198 bp overlap

BRD4 5 datasets

ChIP HAP1 GSE108387.BRD4.HAP1 396 bp overlap

ChIP NCI-H1963 GSE145028.BRD4.NCI-H1963 774 bp overlap

ChIP NCI-H1963_dBET6 GSE145028.BRD4.NCI-H1963_dBET6 287 bp overlap

ChIP NCI-H1963_shASXL3 GSE145028.BRD4.NCI-H1963_shASXL3 774 bp overlap

ChIP NCI-H1963_shNONT GSE145028.BRD4.NCI-H1963_shNONT 774 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF274GAT 251 bp overlap

Motif DE_72h DE_72h-Crx_MA0467.3 6 bp overlap

EBF1 3 datasets

ChIP GM12878 ENCFF813OXE 265 bp overlap

ChIP MUTUL GSE75503.EBF1.MUTUL 593 bp overlap

ChIP NALM-6 GSE126300.EBF1.NALM-6 569 bp overlap

Motif DE_72h DE_72h-EBF3_MA1637.2 9 bp overlap

ChIP HEK293 ENCFF336LFH 425 bp overlap

Motif DE_72h DE_72h-Ebf2_MA1604.2 9 bp overlap

FERD3L 1 dataset

Motif DE_72h DE_72h-FERD3L_MA1485.1 14 bp overlap

FEZF1 2 datasets

ChIP HEK293 ENCFF528YED 259 bp overlap

ChIP HEK293 ENCSR827NWO.FEZF1.HEK293 337 bp overlap

FOXA1 5 datasets

ChIP LNCaP_DSG GSE114737.FOXA1.LNCaP_DSG 205 bp overlap

ChIP LNCaP_R1881 GSE69043.FOXA1.LNCaP_R1881 179 bp overlap

ChIP prostate-cancer_PDX_136 GSE130408.FOXA1.prostate-cancer_PDX_136 167 bp overlap

ChIP prostate-cancer_PDX_189-3 GSE130408.FOXA1.prostate-cancer_PDX_189-3 105 bp overlap

ChIP prostate_P27_T GSE130408.FOXA1.prostate_P27_T 181 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 341 bp overlap

ChIP DE DE-FOXA2-2 269 bp overlap

FOXP1 1 dataset

ChIP SU-DHL-6 ERP010999.FOXP1.SU-DHL-6 246 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 321 bp overlap

ChIP DE DE-GATA4-2 494 bp overlap

GATA6 2 datasets

ChIP DE DE-GATA6-1 294 bp overlap

ChIP DE DE-GATA6-2 481 bp overlap

GLIS2 1 dataset

Motif DE_72h DE_72h-GLIS2_MA0736.1 14 bp overlap

Motif DE_72h DE_72h-GSC_MA0648.2 6 bp overlap

Motif DE_72h DE_72h-GSC2_MA0891.2 6 bp overlap

HOXB13 1 dataset

ChIP prostate-cancer_PDX_189-4 GSE130408.HOXB13.prostate-cancer_PDX_189-4 94 bp overlap

KDM5B 1 dataset

ChIP SUM185_SHCTCF GSE46055.KDM5B.SUM185_SHCTCF 92 bp overlap

KLF1 2 datasets

ChIP HEK293 ENCFF159QSW 358 bp overlap

ChIP HEK293 ENCSR859BMR.KLF1.HEK293 480 bp overlap

KLF11 1 dataset

Motif DE_72h DE_72h-KLF11_MA1512.2 10 bp overlap

KLF14 1 dataset

ChIP HEK293 ENCSR780ESQ.KLF14.HEK293 278 bp overlap

KLF16 1 dataset

Motif DE_72h DE_72h-KLF16_MA0741.1 11 bp overlap

KLF17 2 datasets

ChIP HEK293 ENCFF658MHR 172 bp overlap

ChIP HEK293 ENCSR065WUF.KLF17.HEK293 474 bp overlap

ChIP HAP1 GSE130417.KLF4.HAP1 200 bp overlap

ChIP HEK293 ENCFF599UKL 371 bp overlap

Motif DE_72h DE_72h-KLF9_MA1107.3 11 bp overlap

Motif DE_72h DE_72h-MAX_MA0058.4 6 bp overlap

ChIP NCI-H2171 GSE41105.MAX.NCI-H2171 207 bp overlap

ChIP NCI-H2171 GSE36354.MAX.NCI-H2171 177 bp overlap

ChIP NCI-H2171 GSE41105.MAX.NCI-H2171 173 bp overlap

ChIP P493-6 GSE42262.MAX.P493-6 669 bp overlap

ChIP P493-6 GSE36354.MAX.P493-6 532 bp overlap

ChIP P493-6_24HR GSE125863.MAX.P493-6_24HR 295 bp overlap

ChIP P493-6_24HR GSE125863.MAX.P493-6_24HR 193 bp overlap

ChIP P493-6_CMYC_1H GSE36354.MAX.P493-6_CMYC_1H 419 bp overlap

ChIP P493-6 GSE36354.MED1.P493-6 174 bp overlap

MEF2B 1 dataset

ChIP GM12878 ENCSR177VFS.MEF2B.GM12878 389 bp overlap

MITF 2 datasets

ChIP 501-mel GSE137522.MITF.501-mel 264 bp overlap

ChIP 501-mel_K243Q GSE137522.MITF.501-mel_K243Q 310 bp overlap

Motif DE_72h DE_72h-MLX_MA0663.1 10 bp overlap

MLXIPL 1 dataset

Motif DE_72h DE_72h-MLXIPL_MA0664.2 8 bp overlap

Motif DE_72h DE_72h-MNT_MA0825.2 6 bp overlap

Motif DE_72h DE_72h-MYC_MA0147.4 8 bp overlap

ChIP NCI-H2171 GSE36354.MYC.NCI-H2171 399 bp overlap

ChIP P493-6 GSE77061.MYC.P493-6 347 bp overlap

ChIP P493-6_MST-312 GSE77061.MYC.P493-6_MST-312 283 bp overlap

Mlxip 1 dataset

Motif DE_72h DE_72h-Mlxip_MA0622.2 6 bp overlap

NFE2L1 1 dataset

ChIP WTC11 ENCFF644BPU 377 bp overlap

NFIB 4 datasets

ChIP MCF-7 ENCFF799WGQ 231 bp overlap

ChIP MCF-7 ENCFF925CGH 263 bp overlap

ChIP MCF-7 ENCSR582ZOA.NFIB.MCF-7 416 bp overlap

ChIP MCF-7 ENCSR702BYX.NFIB.MCF-7 404 bp overlap

NFIC 2 datasets

ChIP K-562 ENCSR796ITY.NFIC.K-562 293 bp overlap

ChIP K562 ENCFF167YID 118 bp overlap

NHLH1 1 dataset

Motif DE_72h DE_72h-NHLH1_MA0048.3 9 bp overlap

Neurod2 1 dataset

Motif DE_72h DE_72h-Neurod2_MA1993.2 6 bp overlap

Motif DE_72h DE_72h-OTX1_MA0711.2 6 bp overlap

ChIP WTC11 ENCFF634NAO 245 bp overlap

Olig2 1 dataset

Motif DE_72h DE_72h-Olig2_MA1997.2 6 bp overlap

PITX1 1 dataset

Motif DE_72h DE_72h-PITX1_MA0682.3 6 bp overlap

PITX2 1 dataset

Motif DE_72h DE_72h-PITX2_MA1547.2 8 bp overlap

PITX3 1 dataset

Motif DE_72h DE_72h-PITX3_MA0714.2 6 bp overlap

PRDM1 1 dataset

Motif DE_72h DE_72h-PRDM1_MA0508.4 7 bp overlap

Motif DE_72h DE_72h-Pgr_MA2323.1 17 bp overlap

Pparg::Rxra 1 dataset

Motif DE_72h DE_72h-PpargRxra_MA0065.3 13 bp overlap

Prdm14 1 dataset

Motif DE_72h DE_72h-Prdm14_MA1998.2 8 bp overlap

Ptf1A 1 dataset

Motif DE_72h DE_72h-Ptf1A_MA1619.2 8 bp overlap

RAD21 2 datasets

ChIP HAP1_CTCF GSE126634.RAD21.HAP1_CTCF 193 bp overlap

ChIP HAP1_CTCF GSE126634.RAD21.HAP1_CTCF 320 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 151 bp overlap

RBPJ 2 datasets

ChIP NHEK GSE29498.RBPJ.NHEK 254 bp overlap

ChIP NHEK GSE29498.RBPJ.NHEK 149 bp overlap

RHOXF1 1 dataset

Motif DE_72h DE_72h-RHOXF1_MA0719.2 6 bp overlap

RUNX1 1 dataset

ChIP NALM-6 GSE126300.RUNX1.NALM-6 328 bp overlap

SETDB1 4 datasets

ChIP HEK293 ENCFF676PLV 408 bp overlap

ChIP HEK293 ENCFF676PLV 615 bp overlap

ChIP HEK293 ENCSR348AGV.SETDB1.HEK293 307 bp overlap

ChIP U2OS ENCSR000EYD.SETDB1.U2OS 307 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 360 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 371 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 415 bp overlap

ChIP NHEK GSE29498.SND1.NHEK 263 bp overlap

SOX10 1 dataset

Motif DE_72h DE_72h-SOX10_MA0442.3 6 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 516 bp overlap

SOX21 1 dataset

ChIP neuroepithelilal-cells GSE110505.SOX21.neuroepithelilal-cells 596 bp overlap

Motif DE_72h DE_72h-SOX4_MA0867.3 8 bp overlap

Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap

Motif DE_72h DE_72h-SP8_MA0747.2 11 bp overlap

STAT3 2 datasets

ChIP HCC70 GSE152203.STAT3.HCC70 147 bp overlap

ChIP HCC70_EtOH GSE85579.STAT3.HCC70_EtOH 358 bp overlap

Motif DE_72h DE_72h-Sox6_MA0515.1 10 bp overlap

TFAP4 1 dataset

Motif DE_72h DE_72h-TFAP4_MA0691.1 10 bp overlap

Motif DE_72h DE_72h-TFE3_MA0831.3 10 bp overlap

Motif DE_72h DE_72h-TFEB_MA0692.2 8 bp overlap

Motif DE_72h DE_72h-TFEC_MA0871.3 8 bp overlap

TRIM28 5 datasets

ChIP HEK293 ENCFF265CEM 634 bp overlap

ChIP HEK293 ENCFF582MWI 597 bp overlap

ChIP HEK293 ENCFF582MWI 649 bp overlap

ChIP WIBR3_NAIVE GSE84382.TRIM28.WIBR3_NAIVE 110 bp overlap

ChIP hESC GSE115387.TRIM28.hESC 261 bp overlap

Tcf12 1 dataset

Motif DE_72h DE_72h-Tcf12_MA0521.3 6 bp overlap

Twist2 1 dataset

Motif DE_72h DE_72h-Twist2_MA0633.3 6 bp overlap

ChIP H1 ENCFF090WVU 241 bp overlap

USF2 2 datasets

Motif DE_72h DE_72h-USF2_MA0526.5 10 bp overlap

ChIP WTC11 ENCFF139JAW 417 bp overlap

ChIP HEK293 ENCFF906HIR 282 bp overlap

ChIP HEK293 ENCSR966PJJ.WT1.HEK293 387 bp overlap

ChIP Hep-G2_RBM25-KD GSE120104.YY1.Hep-G2_RBM25-KD 453 bp overlap

ChIP NT2-D1 ENCSR000EXG.YY1.NT2-D1 104 bp overlap

ChIP HEK293 ENCFF997QEP 397 bp overlap

ChIP HEK293 ENCSR692HSE.YY2.HEK293 516 bp overlap

ZBTB48 2 datasets

ChIP HEK293 ENCFF809BPK 465 bp overlap

ChIP HEK293 ENCSR781EQJ.ZBTB48.HEK293 406 bp overlap

ZFHX2 1 dataset

ChIP HEK293 ENCFF167TUA 122 bp overlap

ZNF135 1 dataset

Motif DE_72h DE_72h-ZNF135_MA1587.1 14 bp overlap

ZNF18 1 dataset

ChIP HEK293 ENCSR977HTH.ZNF18.HEK293 247 bp overlap

ZNF263 2 datasets

Motif DE_72h DE_72h-ZNF263_MA0528.3 7 bp overlap

ChIP HEK293 ENCFF336CWQ 591 bp overlap

ZNF281 1 dataset

Motif DE_72h DE_72h-ZNF281_MA1630.3 10 bp overlap

ZNF317 1 dataset

Motif DE_72h DE_72h-ZNF317_MA1593.2 8 bp overlap

ZNF335 2 datasets

ChIP HEK293 ENCFF784SLD 591 bp overlap

ChIP HEK293 ENCSR328SUD.ZNF335.HEK293 227 bp overlap

ZNF35 1 dataset

ChIP HEK293 GSE76494.ZNF35.HEK293 210 bp overlap

ZNF418 1 dataset

Motif DE_72h DE_72h-ZNF418_MA1980.1 15 bp overlap

ZNF460 1 dataset

Motif DE_72h DE_72h-ZNF460_MA1596.1 16 bp overlap

ZNF528 1 dataset

ChIP HEK293 GSE76494.ZNF528.HEK293 600 bp overlap

ZNF561 1 dataset

ChIP HEK293 ENCSR125ULS.ZNF561.HEK293 411 bp overlap

ZNF577 1 dataset

ChIP HEK293 ENCSR776MDR.ZNF577.HEK293 264 bp overlap

ZNF580 2 datasets

ChIP HEK293 ENCFF906MQV 397 bp overlap

ChIP HEK293 ENCSR668HOP.ZNF580.HEK293 311 bp overlap

ZNF610 1 dataset

ChIP HEK293 ENCSR691TXI.ZNF610.HEK293 229 bp overlap

ZNF692 2 datasets

ChIP HEK293 ENCFF040AZE 501 bp overlap

ChIP HEK293 ENCSR418MKG.ZNF692.HEK293 238 bp overlap

ZNF891 1 dataset

ChIP Hep-G2 ENCSR020CLV.ZNF891.Hep-G2 105 bp overlap

ZSCAN5C 2 datasets

ChIP HEK293 ENCFF343DTU 357 bp overlap

ChIP HEK293 ENCSR731AGO.ZSCAN5C.HEK293 226 bp overlap