chr9 : 6,592,227 – 6,592,641
414 bp 82 TFs 4 linked genes
This 414 bp open chromatin element is linked to 4 target genes and is bound by 82 transcription factors.
Linked Genes
4 genes
Distance
Link type
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
GLDC 7.2 kb Proximal Proximity
ENSG00000236924 53.3 kb Distal Multiome
KDM4C 165.1 kb Distal Multiome
UHRF2 179.3 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr9:6,587,227 – 6,597,641
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
82 transcription factors
Source
Cell type
ARID3A 1 dataset
ChIP HepG2 ENCFF341DES 286 bp overlap
ARID4B 1 dataset
ChIP HepG2 ENCFF519OXJ 414 bp overlap
ASH2L 1 dataset
ChIP Hep-G2 ENCSR508LMH.ASH2L.Hep-G2 238 bp overlap
BRD4 1 dataset
ChIP HCT-15 GSE73319.BRD4.HCT-15 414 bp overlap
CDX2 1 dataset
ChIP Caco-2_PROLIF GSE23436.CDX2.Caco-2_PROLIF 156 bp overlap
CEBPA 1 dataset
ChIP HepG2 ENCFF175DFS 101 bp overlap
CEBPB 1 dataset
ChIP MCF-7 ENCSR000BSR.CEBPB.MCF-7 105 bp overlap
CEBPD 1 dataset
Motif DE_60h DE_60h-CEBPD_MA0836.3 8 bp overlap
CREM 1 dataset
ChIP HepG2 ENCFF049UDY 236 bp overlap
EED 1 dataset
ChIP ProEs GSE59087.EED.ProEs 163 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 386 bp overlap
EP300 2 datasets
ChIP Hep-G2 ENCSR000BLW.EP300.Hep-G2 237 bp overlap
ChIP Hep-G2 ENCSR000EDV.EP300.Hep-G2 139 bp overlap
ERG 1 dataset
ChIP VCaP_R1881 GSE49091.ERG.VCaP_R1881 136 bp overlap
EZH2 2 datasets
ChIP DOHH2 ENCFF528GDC 181 bp overlap
ChIP Karpas-422_CPI360-D4 GSE134136.EZH2.Karpas-422_CPI360-D4 298 bp overlap
EZH2_phosphoT487 1 dataset
ChIP DOHH2 ENCSR562NOP.EZH2_phosphoT487.DOHH2 255 bp overlap
FOSL2 1 dataset
ChIP hESC GSE69539.FOSL2.hESC 64 bp overlap
FOXA1 2 datasets
ChIP HepG2 ENCFF361KNY 101 bp overlap
ChIP HepG2 ENCFF740VZW 89 bp overlap
FOXA2 7 datasets
ChIP BJ1-hTERT_CDT1 GSE92491.FOXA2.BJ1-hTERT_CDT1 87 bp overlap
ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.FOXA2.BJ1-hTERT_FOXA2_GATA4_Coexp 235 bp overlap
ChIP Caco-2 GSE66218.FOXA2.Caco-2 268 bp overlap
ChIP DE DE-FOXA2-1 414 bp overlap
ChIP DE DE-FOXA2-2 414 bp overlap
ChIP HepG2 ENCFF533COJ 91 bp overlap
ChIP HepG2 ENCFF570ABM 154 bp overlap
FOXA3 1 dataset
ChIP HepG2 ENCFF005KGL 125 bp overlap
FOXL2 1 dataset
ChIP SVOG-3e_DOX-WT GSE126171.FOXL2.SVOG-3e_DOX-WT 88 bp overlap
FOXP1 2 datasets
ChIP Hep-G2 ENCSR369YUK.FOXP1.Hep-G2 57 bp overlap
ChIP HepG2 ENCFF823ERM 151 bp overlap
GATA2 4 datasets
ChIP ESF GSE108408.GATA2.ESF 104 bp overlap
ChIP ESF GSE108408.GATA2.ESF 164 bp overlap
ChIP Hep-G2 ENCSR897LDT.GATA2.Hep-G2 367 bp overlap
ChIP HepG2 ENCFF905PYM 364 bp overlap
GATA4 7 datasets
ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.GATA4.BJ1-hTERT_FOXA2_GATA4_Coexp 218 bp overlap
ChIP DE DE-GATA4-1 414 bp overlap
ChIP DE DE-GATA4-2 414 bp overlap
ChIP HepG2 ENCFF309FOQ 308 bp overlap
ChIP YCC-3 GSE51705.GATA4.YCC-3 328 bp overlap
ChIP foregut GSE117136.GATA4.foregut 266 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 412 bp overlap
GATA6 14 datasets
ChIP AGS GSE51705.GATA6.AGS 357 bp overlap
ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 370 bp overlap
ChIP DE DE-GATA6-1 414 bp overlap
ChIP DE DE-GATA6-2 414 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 414 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 414 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 414 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 414 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 414 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 414 bp overlap
ChIP YCC-3 GSE51705.GATA6.YCC-3 366 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 414 bp overlap
ChIP foregut GSE117136.GATA6.foregut 264 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 276 bp overlap
GATAD2A 1 dataset
ChIP HepG2 ENCFF252XNH 414 bp overlap
GRHL2 4 datasets
ChIP HBE GSE46194.GRHL2.HBE 160 bp overlap
ChIP MCF-7 GSE109820.GRHL2.MCF-7 270 bp overlap
ChIP MCF-7_E2_45min GSE109820.GRHL2.MCF-7_E2_45min 285 bp overlap
ChIP OVCA429 GSE71018.GRHL2.OVCA429 138 bp overlap
GZF1 1 dataset
ChIP HepG2 ENCFF060TLH 55 bp overlap
HDAC2 1 dataset
ChIP Hep-G2 ENCSR000BMC.HDAC2.Hep-G2 162 bp overlap
HLF 1 dataset
ChIP HepG2 ENCFF854JLR 67 bp overlap
HMG20A 1 dataset
ChIP HepG2 ENCFF599VWU 376 bp overlap
HNF4A 5 datasets
ChIP Caco-2_DIFF GSE23436.HNF4A.Caco-2_DIFF 169 bp overlap
ChIP Caco-2_PROLIF GSE23436.HNF4A.Caco-2_PROLIF 244 bp overlap
Motif DE_48h DE_48h-HNF4A_MA1494.2 14 bp overlap
Motif DE_60h DE_60h-HNF4A_MA1494.2 14 bp overlap
ChIP Hep-G2 ENCSR469FBY.HNF4A.Hep-G2 190 bp overlap
ISL2 2 datasets
Motif DE_60h DE_60h-ISL2_MA0914.2 6 bp overlap
ChIP Hep-G2 ENCSR492IHH.ISL2.Hep-G2 396 bp overlap
JUN 1 dataset
ChIP DE_D2 S02-DE-d2-JUN-exp1 296 bp overlap
KAT8 1 dataset
ChIP HepG2 ENCFF890JFC 414 bp overlap
MAX 2 datasets
ChIP HepG2 ENCFF507HCX 201 bp overlap
ChIP HepG2 ENCFF507HCX 414 bp overlap
NFKBIZ 1 dataset
ChIP Hep-G2 ENCSR235OVI.NFKBIZ.Hep-G2 127 bp overlap
NKX2-3 1 dataset
Motif DE_60h DE_60h-NKX2-3_MA0672.2 8 bp overlap
NR1I3 2 datasets
Motif DE_48h DE_48h-NR1I3_MA1534.2 8 bp overlap
Motif DE_60h DE_60h-NR1I3_MA1534.2 8 bp overlap
NR2C2 2 datasets
Motif DE_48h DE_48h-NR2C2_MA0504.2 14 bp overlap
Motif DE_60h DE_60h-NR2C2_MA0504.2 14 bp overlap
NR2F1 3 datasets
Motif DE_48h DE_48h-NR2F1_MA1537.2 13 bp overlap
Motif DE_60h DE_60h-NR2F1_MA1537.2 13 bp overlap
ChIP HepG2 ENCFF518ZRY 322 bp overlap
NR2F2 4 datasets
ChIP Hep-G2 ENCSR000BVM.NR2F2.Hep-G2 235 bp overlap
ChIP HepG2 ENCFF483TVJ 401 bp overlap
ChIP MCF-7 ENCSR000BUY.NR2F2.MCF-7 359 bp overlap
ChIP uterus_STROMA_ENDOMETRIUM GSE52008.NR2F2.uterus_STROMA_ENDOMETRIUM 233 bp overlap
NR2F6 2 datasets
ChIP Hep-G2 ENCSR518WPL.NR2F6.Hep-G2 281 bp overlap
ChIP HepG2 ENCFF429VKC 411 bp overlap
Nkx3-1 1 dataset
Motif DE_60h DE_60h-Nkx3-1_MA0124.3 7 bp overlap
Nkx3-2 1 dataset
Motif DE_60h DE_60h-Nkx3-2_MA0122.4 10 bp overlap
Nr2f6 2 datasets
Motif DE_48h DE_48h-Nr2f6_MA0677.2 13 bp overlap
Motif DE_60h DE_60h-Nr2f6_MA0677.2 13 bp overlap
PHIP 1 dataset
ChIP HCT-116_MLL1-KO__ab833 GSE101646.PHIP.HCT-116_MLL1-KO__ab833 388 bp overlap
PPARA::RXRA 2 datasets
Motif DE_48h DE_48h-PPARARXRA_MA1148.2 17 bp overlap
Motif DE_60h DE_60h-PPARARXRA_MA1148.2 17 bp overlap
PPARD 2 datasets
Motif DE_48h DE_48h-PPARD_MA1550.2 14 bp overlap
Motif DE_60h DE_60h-PPARD_MA1550.2 14 bp overlap
PPARG 1 dataset
ChIP Hep-G2 ENCSR130VQL.PPARG.Hep-G2 174 bp overlap
PROX1 2 datasets
ChIP HepG2 ENCFF016ZJS 414 bp overlap
ChIP HepG2 ENCFF016ZJS 257 bp overlap
PRPF4 1 dataset
ChIP Hep-G2 ENCSR243LNQ.PRPF4.Hep-G2 169 bp overlap
Prdm15 1 dataset
Motif DE_60h DE_60h-Prdm15_MA1616.2 11 bp overlap
RORA 1 dataset
Motif DE_60h DE_60h-RORA_MA0072.2 11 bp overlap
RORB 1 dataset
Motif DE_60h DE_60h-RORB_MA1150.2 10 bp overlap
RORC 1 dataset
Motif DE_60h DE_60h-RORC_MA1151.2 10 bp overlap
RXRB 2 datasets
Motif DE_48h DE_48h-RXRB_MA0855.1 14 bp overlap
Motif DE_60h DE_60h-RXRB_MA0855.1 14 bp overlap
RXRG 2 datasets
Motif DE_48h DE_48h-RXRG_MA0856.1 14 bp overlap
Motif DE_60h DE_60h-RXRG_MA0856.1 14 bp overlap
Rxra 2 datasets
Motif DE_48h DE_48h-Rxra_MA0512.2 14 bp overlap
Motif DE_60h DE_60h-Rxra_MA0512.2 14 bp overlap
SIX2 1 dataset
Motif DE_60h DE_60h-SIX2_MA1119.2 11 bp overlap
SKI 1 dataset
ChIP Hep-G2 ENCSR754MUD.SKI.Hep-G2 333 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 375 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 414 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 414 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 414 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 414 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 414 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 414 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 376 bp overlap
SMAD4 1 dataset
ChIP Caco-2 GSE112946.SMAD4.Caco-2 293 bp overlap
SMARCB1 1 dataset
ChIP Hep-G2 GSE69566.SMARCB1.Hep-G2 414 bp overlap
SMARCC1 1 dataset
ChIP DE_D1 S15-DE-d1-BAF155-exp1 402 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 299 bp overlap
SUZ12 1 dataset
ChIP Karpas-422_CPI360-D4 GSE134136.SUZ12.Karpas-422_CPI360-D4 414 bp overlap
Stat4 1 dataset
Motif DE_60h DE_60h-Stat4_MA0518.2 10 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 246 bp overlap
TCF7 1 dataset
ChIP Hep-G2 ENCSR444LIN.TCF7.Hep-G2 184 bp overlap
TEAD1 4 datasets
Motif DE_48h DE_48h-TEAD1_MA0090.4 9 bp overlap
Motif DE_60h DE_60h-TEAD1_MA0090.4 9 bp overlap
ChIP HUCCT1 GSE68296.TEAD1.HUCCT1 347 bp overlap
ChIP HepG2 ENCFF661PNM 370 bp overlap
TEAD2 2 datasets
Motif DE_48h DE_48h-TEAD2_MA1121.2 7 bp overlap
Motif DE_60h DE_60h-TEAD2_MA1121.2 7 bp overlap
TEAD3 3 datasets
Motif DE_48h DE_48h-TEAD3_MA0808.1 8 bp overlap
Motif DE_60h DE_60h-TEAD3_MA0808.1 8 bp overlap
ChIP HepG2 ENCFF054UUL 347 bp overlap
TEAD4 9 datasets
Motif DE_48h DE_48h-TEAD4_MA0809.3 8 bp overlap
Motif DE_60h DE_60h-TEAD4_MA0809.3 8 bp overlap
ChIP HUCCT1 GSE68296.TEAD4.HUCCT1 211 bp overlap
ChIP Hep-G2 ENCSR000BRP.TEAD4.Hep-G2 214 bp overlap
ChIP HepG2 ENCFF006QNB 404 bp overlap
ChIP HepG2 ENCFF250NXO 311 bp overlap
ChIP PC-9_1DF GSE131687.TEAD4.PC-9_1DF 386 bp overlap
ChIP PC-9_2DF_DMSO GSE131687.TEAD4.PC-9_2DF_DMSO 348 bp overlap
ChIP SNU-216 GSE44416.TEAD4.SNU-216 254 bp overlap
TFAP2A 1 dataset
ChIP WA09 GSE105081.TFAP2A.WA09 205 bp overlap
THRB 2 datasets
Motif DE_48h DE_48h-THRB_MA1574.2 13 bp overlap
Motif DE_60h DE_60h-THRB_MA1574.2 13 bp overlap
Vdr 2 datasets
Motif DE_48h DE_48h-Vdr_MA0693.4 7 bp overlap
Motif DE_60h DE_60h-Vdr_MA0693.4 7 bp overlap
YAP1 1 dataset
ChIP MCF-7 GSE107013.YAP1.MCF-7 128 bp overlap
YY1AP1 2 datasets
ChIP PC-9_1DF GSE131687.YY1AP1.PC-9_1DF 328 bp overlap
ChIP PC-9_2DF GSE131687.YY1AP1.PC-9_2DF 314 bp overlap
ZGPAT 1 dataset
ChIP Hep-G2 ENCSR704IGU.ZGPAT.Hep-G2 225 bp overlap
ZNF143 1 dataset
ChIP MCF-7 GSE76454.ZNF143.MCF-7 168 bp overlap
ZNF750 1 dataset
ChIP keratinocyte_diff GSE57702.ZNF750.keratinocyte_diff 307 bp overlap
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