chr8 : 129,843,045 – 129,843,736
691 bp 117 TFs 1 linked gene
This 691 bp open chromatin element is linked to CYRIB and is bound by 117 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
CYRIB 173.3 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr8:129,838,045 – 129,848,736
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
117 transcription factors
Source
Cell type
ARID1B 1 dataset
ChIP K-562 ENCSR822CCM.ARID1B.K-562 235 bp overlap
ASCL1 1 dataset
ChIP NCI-H82 GSE69394.ASCL1.NCI-H82 168 bp overlap
Ahr::Arnt 1 dataset
Motif DE_48h DE_48h-AhrArnt_MA0006.2 5 bp overlap
Alx4 1 dataset
Motif DE_60h DE_60h-Alx4_MA0853.2 12 bp overlap
Arid3a 1 dataset
Motif DE_60h DE_60h-Arid3a_MA0151.1 6 bp overlap
Arx 1 dataset
Motif DE_60h DE_60h-Arx_MA0874.2 10 bp overlap
BCOR 1 dataset
ChIP B-cell_GERMINAL_CENTER GSE43350.BCOR.B-cell_GERMINAL_CENTER 136 bp overlap
BRD4 4 datasets
ChIP Kelly_resistant GSE103030.BRD4.Kelly_resistant 182 bp overlap
ChIP Kelly_resistant_JQ1 GSE103030.BRD4.Kelly_resistant_JQ1 159 bp overlap
ChIP PC-3_GDC-R GSE137207.BRD4.PC-3_GDC-R 232 bp overlap
ChIP PC-3_GDC-R_SAHA GSE137207.BRD4.PC-3_GDC-R_SAHA 638 bp overlap
CBFA2T2 2 datasets
ChIP K-562 ENCSR699PVC.CBFA2T2.K-562 290 bp overlap
ChIP K562 ENCFF963TXY 381 bp overlap
CBFA2T3 2 datasets
ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 426 bp overlap
ChIP K562 ENCFF673OEZ 328 bp overlap
CEBPD 1 dataset
ChIP K-562 ENCSR000BVY.CEBPD.K-562 116 bp overlap
CHD4 1 dataset
ChIP SCMC GSE155861.CHD4.SCMC 295 bp overlap
CREBBP 2 datasets
ChIP PC-3 GSE147455.CREBBP.PC-3 128 bp overlap
ChIP PC-3_GDC-resist GSE147455.CREBBP.PC-3_GDC-resist 119 bp overlap
CTCF 1 dataset
Motif DE_60h DE_60h-CTCF_MA1930.2 33 bp overlap
CTCFL 1 dataset
Motif DE_60h DE_60h-CTCFL_MA1102.3 8 bp overlap
CXXC5 1 dataset
ChIP K562 ENCFF497CZN 490 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 384 bp overlap
EP300 1 dataset
ChIP PC-3 GSE147455.EP300.PC-3 168 bp overlap
ESRRG 1 dataset
ChIP cardiomyocyte GSE113760.ESRRG.cardiomyocyte 378 bp overlap
ETS1 1 dataset
ChIP cardiomyocyte_D9 GSE129986.ETS1.cardiomyocyte_D9 243 bp overlap
ETV2::FIGLA 1 dataset
Motif DE_60h DE_60h-ETV2FIGLA_MA1941.2 13 bp overlap
ETV5::FIGLA 1 dataset
Motif DE_60h DE_60h-ETV5FIGLA_MA1945.2 14 bp overlap
FEZF1 3 datasets
ChIP HEK293 ENCFF528YED 389 bp overlap
ChIP HEK293 ENCSR827NWO.FEZF1.HEK293 410 bp overlap
ChIP HEK293 GSE76494.FEZF1.HEK293 313 bp overlap
FIGLA 1 dataset
Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap
FLI1 2 datasets
ChIP A-673_1_KRAB_GFP GSE106914.FLI1.A-673_1_KRAB_GFP 249 bp overlap
ChIP A-673_2_KRAB_eSOX2_1 GSE106914.FLI1.A-673_2_KRAB_eSOX2_1 262 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 545 bp overlap
ChIP DE DE-FOXA2-2 597 bp overlap
GATA1 3 datasets
ChIP HUDEP-2_30min GSE104676.GATA1.HUDEP-2_30min 132 bp overlap
ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 261 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 233 bp overlap
GATA2 1 dataset
ChIP K562 ENCFF544PCK 251 bp overlap
GATA4 4 datasets
ChIP DE DE-GATA4-1 664 bp overlap
ChIP DE DE-GATA4-2 660 bp overlap
ChIP Hep-G2 GSE135714.GATA4.Hep-G2 531 bp overlap
ChIP foregut GSE117136.GATA4.foregut 262 bp overlap
GATA6 9 datasets
ChIP DE DE-GATA6-1 668 bp overlap
ChIP DE DE-GATA6-2 655 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 412 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 549 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 435 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 691 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 577 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 530 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 676 bp overlap
HAND2 2 datasets
Motif DE_48h DE_48h-HAND2_MA1638.2 6 bp overlap
Motif DE_60h DE_60h-HAND2_MA1638.2 6 bp overlap
HDAC1 1 dataset
ChIP K-562 ENCSR387UWP.HDAC1.K-562 240 bp overlap
HDAC2 2 datasets
ChIP K-562 ENCSR893WSB.HDAC2.K-562 265 bp overlap
ChIP RH4_DMSO-6H GSE116344.HDAC2.RH4_DMSO-6H 205 bp overlap
HOXD13 1 dataset
ChIP HEK293 ENCFF590OUV 365 bp overlap
IKZF3 1 dataset
ChIP HEK293 ENCSR304AMN.IKZF3.HEK293 184 bp overlap
ISL2 1 dataset
Motif DE_60h DE_60h-ISL2_MA0914.2 6 bp overlap
KDM1A 1 dataset
ChIP K-562 ENCSR360HRA.KDM1A.K-562 264 bp overlap
KLF5 1 dataset
ChIP HEK293_E419K GSE88976.KLF5.HEK293_E419K 274 bp overlap
MAX 2 datasets
ChIP NCI-H2171 GSE36354.MAX.NCI-H2171 399 bp overlap
ChIP NCI-H2171 GSE41105.MAX.NCI-H2171 372 bp overlap
MAZ 1 dataset
ChIP HEK293 GSE76494.MAZ.HEK293 150 bp overlap
MED1 1 dataset
ChIP NCI-H2171 GSE36354.MED1.NCI-H2171 232 bp overlap
MEIS1 2 datasets
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
MGA 2 datasets
Motif DE_48h DE_48h-MGA_MA0801.1 8 bp overlap
Motif DE_60h DE_60h-MGA_MA0801.1 8 bp overlap
MSC 1 dataset
Motif DE_48h DE_48h-MSC_MA0665.1 10 bp overlap
MYC 1 dataset
ChIP NCI-H2171 GSE36354.MYC.NCI-H2171 426 bp overlap
MYCN 1 dataset
ChIP CHP-134 GSE129588.MYCN.CHP-134 205 bp overlap
MYF6 1 dataset
Motif DE_48h DE_48h-MYF6_MA0667.1 10 bp overlap
MYOD1 5 datasets
Motif DE_48h DE_48h-MYOD1_MA0499.3 9 bp overlap
ChIP RD GSE137168.MYOD1.RD 196 bp overlap
ChIP RD_shSNAI2 GSE137168.MYOD1.RD_shSNAI2 275 bp overlap
ChIP RH30_DMSO GSE85169.MYOD1.RH30_DMSO 240 bp overlap
ChIP rhabdomyosarcoma GSE50413.MYOD1.rhabdomyosarcoma 109 bp overlap
MZF1 1 dataset
ChIP HEK293 ENCSR298QUH.MZF1.HEK293 334 bp overlap
NANOG 2 datasets
ChIP WA01 ENCSR000BMT.NANOG.WA01 124 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 377 bp overlap
NEUROD1 2 datasets
ChIP D341-Med_shGFP GSE92582.NEUROD1.D341-Med_shGFP 691 bp overlap
ChIP NCI-H524 GSE69394.NEUROD1.NCI-H524 122 bp overlap
NEUROG2 6 datasets
Motif DE_48h DE_48h-NEUROG2_MA1642.2 7 bp overlap
Motif DE_60h DE_60h-NEUROG2_MA1642.2 7 bp overlap
ChIP MRC-5_NFD_02DPT GSE75910.NEUROG2.MRC-5_NFD_02DPT 282 bp overlap
ChIP MRC-5_NFD_05DPT GSE75910.NEUROG2.MRC-5_NFD_05DPT 188 bp overlap
ChIP MRC-5_NFD_1DPT GSE75910.NEUROG2.MRC-5_NFD_1DPT 282 bp overlap
ChIP MRC-5_N_02DPT GSE75910.NEUROG2.MRC-5_N_02DPT 272 bp overlap
NFIL3 1 dataset
Motif DE_60h DE_60h-NFIL3_MA0025.3 9 bp overlap
NKX2-3 1 dataset
Motif DE_60h DE_60h-NKX2-3_MA0672.2 8 bp overlap
NKX2-4 1 dataset
Motif DE_60h DE_60h-NKX2-4_MA2003.2 8 bp overlap
NKX2-5 1 dataset
ChIP hESC_ab3584 GSE89457.NKX2-5.hESC_ab3584 254 bp overlap
NKX2-8 1 dataset
Motif DE_60h DE_60h-NKX2-8_MA0673.2 8 bp overlap
Nkx3-1 1 dataset
Motif DE_60h DE_60h-Nkx3-1_MA0124.3 7 bp overlap
Nkx3-2 1 dataset
Motif DE_60h DE_60h-Nkx3-2_MA0122.4 10 bp overlap
OSR2 5 datasets
Motif DE_48h DE_48h-OSR2_MA1646.2 8 bp overlap
Motif DE_60h DE_60h-OSR2_MA1646.2 8 bp overlap
ChIP HEK293 ENCFF875BDB 303 bp overlap
ChIP HEK293 ENCSR324LTM.OSR2.HEK293 430 bp overlap
ChIP HEK293 GSE76494.OSR2.HEK293 274 bp overlap
PML 1 dataset
ChIP K-562 ENCSR000BQY.PML.K-562 161 bp overlap
PRDM4 2 datasets
ChIP HEK293 ENCFF069PHD 385 bp overlap
ChIP HEK293 ENCSR443MVV.PRDM4.HEK293 251 bp overlap
PRDM6 3 datasets
ChIP HEK293 ENCFF283AJL 181 bp overlap
ChIP HEK293 ENCSR892QHR.PRDM6.HEK293 472 bp overlap
ChIP HEK293 GSE76494.PRDM6.HEK293 154 bp overlap
Ptf1A 1 dataset
Motif DE_48h DE_48h-Ptf1A_MA1620.2 8 bp overlap
RARA 2 datasets
ChIP hiPSC_D3 GSE109172.RARA.hiPSC_D3 284 bp overlap
ChIP hiPSC_D4 GSE109172.RARA.hiPSC_D4 341 bp overlap
RFX4 1 dataset
Motif DE_60h DE_60h-RFX4_MA0799.3 13 bp overlap
Rhox11 2 datasets
Motif DE_48h DE_48h-Rhox11_MA0629.2 9 bp overlap
Motif DE_60h DE_60h-Rhox11_MA0629.2 9 bp overlap
SCRT1 2 datasets
ChIP HEK293 ENCFF513YVP 417 bp overlap
ChIP HEK293 ENCSR605MGM.SCRT1.HEK293 474 bp overlap
SIRT6 1 dataset
ChIP K-562 ENCSR000AUB.SIRT6.K-562 393 bp overlap
SIX2 2 datasets
Motif DE_48h DE_48h-SIX2_MA1119.2 11 bp overlap
Motif DE_60h DE_60h-SIX2_MA1119.2 11 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 689 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 550 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 473 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 527 bp overlap
SMAD3 1 dataset
ChIP endoderm GSE29422.SMAD3.endoderm 177 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 188 bp overlap
SNAI2 2 datasets
Motif DE_48h DE_48h-SNAI2_MA0745.3 8 bp overlap
ChIP RD GSE137168.SNAI2.RD 378 bp overlap
SNAI3 1 dataset
Motif DE_48h DE_48h-SNAI3_MA1559.2 9 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 397 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 544 bp overlap
SP5 1 dataset
Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap
T 2 datasets
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 179 bp overlap
ChIP H9_MESODERM GSE60606.T.H9_MESODERM 183 bp overlap
TAL1 8 datasets
ChIP K-562 ENCSR106FRG.TAL1.K-562 271 bp overlap
ChIP K-562 ENCSR000EHB.TAL1.K-562 114 bp overlap
ChIP K-562_dCas9-KRAB GSE132212.TAL1.K-562_dCas9-KRAB 257 bp overlap
ChIP K-562_dCas9-LSD1 GSE132212.TAL1.K-562_dCas9-LSD1 251 bp overlap
ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 245 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 293 bp overlap
ChIP K-562_sgGal4 GSE132212.TAL1.K-562_sgGal4 161 bp overlap
ChIP ProEs GSE59087.TAL1.ProEs 193 bp overlap
TBX1 2 datasets
Motif DE_48h DE_48h-TBX1_MA0805.1 8 bp overlap
Motif DE_60h DE_60h-TBX1_MA0805.1 8 bp overlap
TBX15 2 datasets
Motif DE_48h DE_48h-TBX15_MA0803.1 8 bp overlap
Motif DE_60h DE_60h-TBX15_MA0803.1 8 bp overlap
TBX18 2 datasets
Motif DE_48h DE_48h-TBX18_MA1565.2 9 bp overlap
Motif DE_60h DE_60h-TBX18_MA1565.2 9 bp overlap
TBX4 2 datasets
Motif DE_48h DE_48h-TBX4_MA0806.1 8 bp overlap
Motif DE_60h DE_60h-TBX4_MA0806.1 8 bp overlap
TCF12 2 datasets
ChIP K-562 ENCSR744WOO.TCF12.K-562 284 bp overlap
ChIP K562 ENCFF931DJY 391 bp overlap
TEAD4 3 datasets
ChIP HEK293_siCtrl GSE130135.TEAD4.HEK293_siCtrl 214 bp overlap
ChIP HEK293_siE1A GSE130135.TEAD4.HEK293_siE1A 346 bp overlap
ChIP K562 ENCFF673NIK 168 bp overlap
TP73 2 datasets
Motif DE_48h DE_48h-TP73_MA0861.2 16 bp overlap
Motif DE_60h DE_60h-TP73_MA0861.2 16 bp overlap
Tcf21 1 dataset
Motif DE_48h DE_48h-Tcf21_MA0832.2 10 bp overlap
YY1 1 dataset
ChIP Hep-G2_RBM25-KD GSE120104.YY1.Hep-G2_RBM25-KD 337 bp overlap
YY1AP1 1 dataset
ChIP HEK293_siCtrl GSE130135.YY1AP1.HEK293_siCtrl 390 bp overlap
ZBTB18 1 dataset
Motif DE_48h DE_48h-ZBTB18_MA0698.2 11 bp overlap
ZBTB42 1 dataset
ChIP HEK293 GSE76494.ZBTB42.HEK293 250 bp overlap
ZBTB7A 1 dataset
ChIP HUDEP-2 GSE103445.ZBTB7A.HUDEP-2 315 bp overlap
ZEB1 1 dataset
Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap
ZIC1 1 dataset
Motif DE_60h DE_60h-ZIC1_MA0696.1 14 bp overlap
ZIC2 1 dataset
ChIP HEK293 ENCFF033NQQ 330 bp overlap
ZIC4 1 dataset
Motif DE_60h DE_60h-ZIC4_MA0751.2 14 bp overlap
ZIC5 1 dataset
Motif DE_60h DE_60h-ZIC5_MA1584.2 15 bp overlap
ZNF16 1 dataset
Motif DE_60h DE_60h-ZNF16_MA1654.2 21 bp overlap
ZNF18 1 dataset
ChIP HEK293 ENCSR977HTH.ZNF18.HEK293 233 bp overlap
ZNF189 2 datasets
Motif DE_48h DE_48h-ZNF189_MA1725.2 9 bp overlap
Motif DE_60h DE_60h-ZNF189_MA1725.2 9 bp overlap
ZNF28 1 dataset
ChIP HEK293T GSE78099.ZNF28.HEK293T 191 bp overlap
ZNF341 4 datasets
Motif DE_60h DE_60h-ZNF341_MA1655.2 8 bp overlap
ChIP HEK293 ENCFF944VMC 345 bp overlap
ChIP HEK293 ENCSR185FOY.ZNF341.HEK293 402 bp overlap
ChIP HEK293 GSE76494.ZNF341.HEK293 191 bp overlap
ZNF35 1 dataset
ChIP HEK293 GSE76494.ZNF35.HEK293 167 bp overlap
ZNF423 2 datasets
ChIP HEK293 ENCFF937QHI 357 bp overlap
ChIP HEK293 ENCSR477OJI.ZNF423.HEK293 267 bp overlap
ZNF449 2 datasets
ChIP HEK293 ENCFF764ZIC 375 bp overlap
ChIP HEK293 ENCSR738SLS.ZNF449.HEK293 333 bp overlap
ZNF675 2 datasets
Motif DE_48h DE_48h-ZNF675_MA1714.2 19 bp overlap
Motif DE_60h DE_60h-ZNF675_MA1714.2 19 bp overlap
ZNF701 2 datasets
Motif DE_48h DE_48h-ZNF701_MA1987.2 17 bp overlap
Motif DE_60h DE_60h-ZNF701_MA1987.2 17 bp overlap
ZNF75A 2 datasets
Motif DE_48h DE_48h-ZNF75A_MA2097.1 12 bp overlap
Motif DE_60h DE_60h-ZNF75A_MA2097.1 12 bp overlap
ZNF770 2 datasets
ChIP HEK293 ENCSR242BGR.ZNF770.HEK293 331 bp overlap
ChIP HEK293 GSE76494.ZNF770.HEK293 232 bp overlap
ZNF778 1 dataset
ChIP HEK293 GSE76494.ZNF778.HEK293 174 bp overlap
ZNF843 2 datasets
ChIP HEK293 ENCFF241QRH 445 bp overlap
ChIP HEK293 ENCSR502KPJ.ZNF843.HEK293 351 bp overlap
ZNF85 2 datasets
Motif DE_48h DE_48h-ZNF85_MA1720.2 12 bp overlap
Motif DE_60h DE_60h-ZNF85_MA1720.2 12 bp overlap
ZSCAN30 2 datasets
ChIP HEK293 ENCFF082YBI 337 bp overlap
ChIP HEK293 ENCSR768VNZ.ZSCAN30.HEK293 221 bp overlap
Zic1::Zic2 2 datasets
Motif DE_48h DE_48h-Zic1Zic2_MA1628.2 7 bp overlap
Motif DE_60h DE_60h-Zic1Zic2_MA1628.2 7 bp overlap
Zic3 2 datasets
Motif DE_48h DE_48h-Zic3_MA0697.3 7 bp overlap
Motif DE_60h DE_60h-Zic3_MA0697.3 7 bp overlap
Huangfu Lab · Publications · Resources · Contact