chr2:85,178,933–85,179,785

chr2 : 85,178,933 – 85,179,785

852 bp 95 TFs 9 linked genes

This 852 bp open chromatin element is linked to 9 target genes and is bound by 95 transcription factors.

Linked Genes

9 genes

Gene	Expression	Dist. to TSS	Distance	Link type
TCF7L1		45.9 kb	Distal	Multiome
TGOLN2		148.7 kb	Distal	Multiome
RETSAT		175.3 kb	Distal	Multiome
ELMOD3		175.5 kb	Distal	Multiome
KCMF1		208.2 kb	Distal	Multiome
CAPG		234.8 kb	Distal	Multiome
ENSG00000287625		253.3 kb	Distal	Multiome
TMSB10		273.6 kb	Distal	Multiome
TRABD2A		298.2 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

95 transcription factors

ASH2L 2 datasets

ChIP WA01 ENCSR850KIP.ASH2L.WA01 267 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 298 bp overlap

ATF2 2 datasets

ChIP WA01 ENCSR000BQU.ATF2.WA01 147 bp overlap

ChIP WA01 ENCSR000BQU.ATF2.WA01 204 bp overlap

BCL6B 1 dataset

Motif DE_72h DE_72h-BCL6B_MA0731.1 17 bp overlap

BCOR 2 datasets

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 500 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 190 bp overlap

BRD4 2 datasets

ChIP HEK293_sgMYOD GSE129407.BRD4.HEK293_sgMYOD 215 bp overlap

ChIP RH4 GSE83726.BRD4.RH4 232 bp overlap

CDK8 2 datasets

ChIP leiomyoma_PT886 GSE128230.CDK8.leiomyoma_PT886 90 bp overlap

ChIP myometrium_PT916 GSE128230.CDK8.myometrium_PT916 52 bp overlap

ChIP retina_Hu3 GSE137311.CRX.retina_Hu3 188 bp overlap

ChIP retina_Hu6 GSE137311.CRX.retina_Hu6 216 bp overlap

Cebpa 2 datasets

ChIP BLaER1 ENCFF274GAT 211 bp overlap

ChIP BLaER1 ENCFF364PUR 117 bp overlap

Motif DE_72h DE_72h-Crx_MA0467.3 6 bp overlap

Motif DE_72h DE_72h-Crx_MA0467.3 6 bp overlap

Dmbx1 1 dataset

Motif DE_72h DE_72h-Dmbx1_MA0883.2 10 bp overlap

ChIP K562 ENCFF511ZZZ 172 bp overlap

EOMES 2 datasets

ChIP hESC GSE26097.EOMES.hESC 135 bp overlap

ChIP hESC GSE26097.EOMES.hESC 260 bp overlap

ChIP MCF-7_PaPE-1_OA GSE93510.ESR1.MCF-7_PaPE-1_OA 168 bp overlap

ChIP cardiomyocyte_D2 GSE129986.ETS1.cardiomyocyte_D2 180 bp overlap

ChIP RH30_DMSO GSE85169.EZH2.RH30_DMSO 136 bp overlap

FEZF1 3 datasets

ChIP HEK293 ENCFF528YED 266 bp overlap

ChIP HEK293 ENCSR827NWO.FEZF1.HEK293 414 bp overlap

ChIP HEK293 GSE76494.FEZF1.HEK293 186 bp overlap

FOSL2 1 dataset

ChIP NPC_K755R-pos GSE122631.FOSL2.NPC_K755R-pos 116 bp overlap

FOXA1 1 dataset

ChIP MCF-7 GSE140185.FOXA1.MCF-7 187 bp overlap

FOXA2 3 datasets

ChIP DE DE-FOXA2-1 275 bp overlap

ChIP DE DE-FOXA2-1 306 bp overlap

ChIP DE DE-FOXA2-2 231 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 360 bp overlap

ChIP DE DE-GATA4-2 304 bp overlap

GATA6 10 datasets

ChIP DE DE-GATA6-1 307 bp overlap

ChIP DE DE-GATA6-2 369 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 339 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 557 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 177 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 598 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 394 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 302 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 233 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 350 bp overlap

GLIS1 2 datasets

ChIP HEK293 ENCFF299RSE 345 bp overlap

ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 412 bp overlap

Motif DE_72h DE_72h-GSC_MA0648.2 6 bp overlap

Motif DE_72h DE_72h-GSC_MA0648.2 6 bp overlap

GSC2 2 datasets

Motif DE_72h DE_72h-GSC2_MA0891.2 6 bp overlap

Motif DE_72h DE_72h-GSC2_MA0891.2 6 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 340 bp overlap

ChIP leiomyoma_PT848 GSE128230.JUN.leiomyoma_PT848 75 bp overlap

KLF17 1 dataset

Motif DE_72h DE_72h-KLF17_MA1514.2 14 bp overlap

KLF5 2 datasets

ChIP HEK293 GSE88976.KLF5.HEK293 182 bp overlap

ChIP HEK293_E419Q GSE88976.KLF5.HEK293_E419Q 167 bp overlap

MAFF 6 datasets

ChIP GM12878 ENCSR237YZZ.MAFF.GM12878 92 bp overlap

ChIP HeLa-S3 ENCFF783SBT 98 bp overlap

ChIP HeLa-S3 ENCSR140DSL.MAFF.HeLa-S3 155 bp overlap

ChIP HepG2 ENCFF452YUT 124 bp overlap

ChIP K-562 ENCSR000EGI.MAFF.K-562 179 bp overlap

ChIP K562 ENCFF071YKK 74 bp overlap

MAFG 2 datasets

ChIP K-562 ENCSR818DQV.MAFG.K-562 283 bp overlap

ChIP K562 ENCFF455EEO 149 bp overlap

MAFK 15 datasets

ChIP A549 ENCFF371EPR 240 bp overlap

ChIP GM12878 ENCFF605LFT 129 bp overlap

ChIP H1 ENCFF854XWE 122 bp overlap

ChIP HeLa-S3 ENCFF304XGR 154 bp overlap

ChIP HeLa-S3 ENCSR000ECK.MAFK.HeLa-S3 197 bp overlap

ChIP Hep-G2 ENCSR000EDZ.MAFK.Hep-G2 183 bp overlap

ChIP HepG2 ENCFF743ZOF 123 bp overlap

ChIP HepG2 ENCFF767LDG 96 bp overlap

ChIP IMR-90 ENCFF336DHZ 132 bp overlap

ChIP K-562 ENCSR000EGX.MAFK.K-562 174 bp overlap

ChIP K562 ENCFF380WHM 71 bp overlap

ChIP MCF-7 ENCFF558JLG 218 bp overlap

ChIP MCF-7 ENCSR555PBN.MAFK.MCF-7 261 bp overlap

ChIP OCI-Ly7 GSE47784.MAFK.OCI-Ly7 196 bp overlap

ChIP WA01 ENCSR000EBS.MAFK.WA01 174 bp overlap

MED1 3 datasets

ChIP HUVEC-C_siCTL GSE124892.MED1.HUVEC-C_siCTL 343 bp overlap

ChIP RH4 GSE83726.MED1.RH4 448 bp overlap

ChIP dopaminergic-neuron_Dopamine_neurons GSE93905.MED1.dopaminergic-neuron_Dopamine_neurons 82 bp overlap

MED12 2 datasets

ChIP leiomyoma_PT886 GSE128230.MED12.leiomyoma_PT886 85 bp overlap

ChIP myometrium_PT916 GSE128230.MED12.myometrium_PT916 56 bp overlap

MEF2D 1 dataset

ChIP retina_Hu21 GSE137311.MEF2D.retina_Hu21 217 bp overlap

MRTFB 1 dataset

ChIP A-673-clone-Asp114 GSE92738.MRTFB.A-673-clone-Asp114 154 bp overlap

ChIP RH4 GSE83726.MYCN.RH4 205 bp overlap

MYOD1 2 datasets

ChIP RD GSE137168.MYOD1.RD 200 bp overlap

ChIP RH4 GSE83726.MYOD1.RH4 138 bp overlap

NANOG 4 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 567 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 220 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 366 bp overlap

ChIP hESC GSE18292.NANOG.hESC 130 bp overlap

NEUROD1 1 dataset

ChIP D283-Med GSE92582.NEUROD1.D283-Med 240 bp overlap

NKX2-2 1 dataset

Motif DE_72h DE_72h-NKX2-2_MA1645.2 8 bp overlap

ChIP retina_Hu13 GSE137311.NRL.retina_Hu13 232 bp overlap

OSR2 3 datasets

ChIP HEK293 ENCFF875BDB 321 bp overlap

ChIP HEK293 ENCSR324LTM.OSR2.HEK293 422 bp overlap

ChIP HEK293 GSE76494.OSR2.HEK293 242 bp overlap

OTX1 2 datasets

Motif DE_72h DE_72h-OTX1_MA0711.2 6 bp overlap

Motif DE_72h DE_72h-OTX1_MA0711.2 6 bp overlap

OTX2 2 datasets

Motif DE_72h DE_72h-OTX2_MA0712.3 7 bp overlap

ChIP retina_Hu7 GSE137311.OTX2.retina_Hu7 165 bp overlap

ChIP myometrium_NP2 GSE137550.PGR.myometrium_NP2 180 bp overlap

PITX1 2 datasets

Motif DE_72h DE_72h-PITX1_MA0682.3 6 bp overlap

Motif DE_72h DE_72h-PITX1_MA0682.3 6 bp overlap

PITX2 1 dataset

Motif DE_72h DE_72h-PITX2_MA1547.2 8 bp overlap

PITX3 2 datasets

Motif DE_72h DE_72h-PITX3_MA0714.2 6 bp overlap

Motif DE_72h DE_72h-PITX3_MA0714.2 6 bp overlap

POLR2A 1 dataset

ChIP SK-N-MC ENCFF088IVG 330 bp overlap

POU5F1 2 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 808 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 358 bp overlap

PRDM4 2 datasets

ChIP HEK293 ENCFF069PHD 414 bp overlap

ChIP HEK293 ENCSR443MVV.PRDM4.HEK293 737 bp overlap

PRDM6 3 datasets

ChIP HEK293 ENCFF283AJL 333 bp overlap

ChIP HEK293 ENCSR892QHR.PRDM6.HEK293 374 bp overlap

ChIP HEK293 GSE76494.PRDM6.HEK293 265 bp overlap

ChIP Hep-G2 ENCSR000EEA.RFX5.Hep-G2 84 bp overlap

RHOXF1 2 datasets

Motif DE_72h DE_72h-RHOXF1_MA0719.2 6 bp overlap

Motif DE_72h DE_72h-RHOXF1_MA0719.2 6 bp overlap

ChIP K-562 ENCSR138FUZ.RNF2.K-562 117 bp overlap

SCRT1 1 dataset

ChIP HEK293 ENCSR605MGM.SCRT1.HEK293 286 bp overlap

SCRT2 1 dataset

Motif DE_72h DE_72h-SCRT2_MA0744.3 10 bp overlap

SIX2 2 datasets

ChIP HEK GSE73865.SIX2.HEK 250 bp overlap

ChIP kidney_fetal_17w GSE75948.SIX2.kidney_fetal_17w 157 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 852 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 617 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 301 bp overlap

SMAD3 1 dataset

ChIP BG03_DIFF_48H GSE36578.SMAD3.BG03_DIFF_48H 160 bp overlap

SMARCA2 1 dataset

ChIP SK-N-MC_shEWSFLI1 GSE94275.SMARCA2.SK-N-MC_shEWSFLI1 247 bp overlap

SMARCA4 3 datasets

ChIP NPC_K755R-siAP GSE122631.SMARCA4.NPC_K755R-siAP 139 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 791 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 410 bp overlap

SMARCB1 3 datasets

ChIP hiPSC GSE124903.SMARCB1.hiPSC 852 bp overlap

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 198 bp overlap

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 205 bp overlap

SMARCC1 4 datasets

ChIP SK-N-MC GSE94275.SMARCC1.SK-N-MC 180 bp overlap

ChIP SK-N-MC_shGFP GSE94275.SMARCC1.SK-N-MC_shGFP 104 bp overlap

ChIP hiPSC GSE124903.SMARCC1.hiPSC 612 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 206 bp overlap

SNAI2 1 dataset

ChIP RD GSE137168.SNAI2.RD 253 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 141 bp overlap

ChIP HNSC GSE69479.SOX2.HNSC 92 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 131 bp overlap

ChIP HEK293 GSE76494.SP4.HEK293 223 bp overlap

ChIP HEK293 ENCSR468IJT.SP7.HEK293 260 bp overlap

ChIP H1 ENCFF478SZO 485 bp overlap

TCF12 1 dataset

ChIP WA01 ENCSR000BIT.TCF12.WA01 109 bp overlap

TFAP2C 1 dataset

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 232 bp overlap

ChIP HEK293T GSE61048.USP7.HEK293T 206 bp overlap

ChIP HEK293 ENCSR966PJJ.WT1.HEK293 230 bp overlap

ChIP Hep-G2_NC GSE120104.YY1.Hep-G2_NC 310 bp overlap

ChIP Hep-G2_RBM25-KD GSE120104.YY1.Hep-G2_RBM25-KD 384 bp overlap

ZBTB8A 1 dataset

ChIP HEK293 ENCSR481FEC.ZBTB8A.HEK293 242 bp overlap

ChIP HEK293 ENCFF033NQQ 408 bp overlap

ZNF189 1 dataset

ChIP HEK293 ENCSR163RYW.ZNF189.HEK293 377 bp overlap

ZNF205 1 dataset

ChIP HEK293T GSE78099.ZNF205.HEK293T 149 bp overlap

ZNF24 1 dataset

ChIP HEK293 ENCSR984MDV.ZNF24.HEK293 329 bp overlap

ZNF283 1 dataset

ChIP HEK293T GSE78099.ZNF283.HEK293T 157 bp overlap

ZNF316 1 dataset

ChIP K562 ENCFF838QCD 155 bp overlap

ZNF35 1 dataset

ChIP HEK293 GSE76494.ZNF35.HEK293 153 bp overlap

ZNF366 1 dataset

ChIP HEK293 ENCSR106EBH.ZNF366.HEK293 299 bp overlap

ZNF394 2 datasets

ChIP HEK293 ENCFF236OPX 434 bp overlap

ChIP HEK293 ENCSR125DNC.ZNF394.HEK293 365 bp overlap

ZNF423 2 datasets

ChIP HEK293 ENCFF937QHI 357 bp overlap

ChIP HEK293 ENCSR477OJI.ZNF423.HEK293 316 bp overlap

ZNF467 1 dataset

ChIP HEK293 GSE76494.ZNF467.HEK293 146 bp overlap

ZNF582 1 dataset

Motif DE_72h DE_72h-ZNF582_MA1983.2 19 bp overlap

ZNF629 1 dataset

ChIP HEK293 ENCSR351NON.ZNF629.HEK293 270 bp overlap

ZNF677 1 dataset

Motif DE_72h DE_72h-ZNF677_MA2101.1 12 bp overlap

ZNF778 2 datasets

ChIP HEK293 GSE76494.ZNF778.HEK293 315 bp overlap

ChIP HEK293T GSE78099.ZNF778.HEK293T 313 bp overlap

ZNF843 2 datasets

ChIP HEK293 ENCFF241QRH 445 bp overlap

ChIP HEK293 ENCSR502KPJ.ZNF843.HEK293 253 bp overlap

ZSCAN5C 2 datasets

ChIP HEK293 ENCFF343DTU 357 bp overlap

ChIP HEK293 ENCSR731AGO.ZSCAN5C.HEK293 216 bp overlap

Zic1::Zic2 1 dataset

Motif DE_72h DE_72h-Zic1Zic2_MA1628.2 7 bp overlap

Motif DE_72h DE_72h-Zic3_MA0697.3 7 bp overlap