chr2:64,252,396–64,252,854

chr2 : 64,252,396 – 64,252,854

458 bp 93 TFs 7 linked genes

This 458 bp open chromatin element is linked to 7 target genes and is bound by 93 transcription factors.

Linked Genes

7 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000288932		20.9 kb	Distal	Multiome
ENSG00000225889		24.4 kb	Distal	Multiome
PELI1		108.4 kb	Distal	Multiome+HiCAR
LGALSL-DT		201.2 kb	Distal	Multiome
LGALSL		201.7 kb	Distal	Multiome
VPS54		233.3 kb	Distal	Multiome
AFTPH		271.6 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

93 transcription factors

ChIP K562 ENCFF583EEH 236 bp overlap

ARID1B 1 dataset

ChIP K562 ENCFF938UXQ 389 bp overlap

ARNT 2 datasets

ChIP K562 ENCFF291CXK 191 bp overlap

ChIP K562 ENCFF703HVX 161 bp overlap

ChIP K562 ENCFF817JQF 415 bp overlap

ATF3 4 datasets

ChIP K562 ENCFF604FPV 331 bp overlap

ChIP K562 ENCFF921JQW 389 bp overlap

ChIP K562 ENCFF921JQW 185 bp overlap

ChIP K562 ENCFF965VXT 170 bp overlap

ChIP K562 ENCFF308SKS 77 bp overlap

Atoh1 1 dataset

Motif DE_12h DE_12h-Atoh1_MA1467.3 7 bp overlap

BACH1 1 dataset

ChIP H1 ENCFF282VDB 214 bp overlap

CBFA2T2 1 dataset

ChIP K562 ENCFF963TXY 175 bp overlap

CBFA2T3 1 dataset

ChIP K562 ENCFF673OEZ 252 bp overlap

CC2D1A 1 dataset

ChIP K562 ENCFF567XUT 288 bp overlap

ChIP WA01 ENCSR000AQK.CHD1.WA01 133 bp overlap

ChIP K562 ENCFF180STA 199 bp overlap

DPF2 2 datasets

ChIP K562 ENCFF739JDE 319 bp overlap

ChIP K562 ENCFF775HUO 371 bp overlap

ChIP K562 ENCFF622HMZ 324 bp overlap

EGR1 2 datasets

ChIP K562 ENCFF113OPQ 373 bp overlap

ChIP K562 ENCFF895KGN 147 bp overlap

ChIP K562 ENCFF511ZZZ 249 bp overlap

EP300 1 dataset

ChIP K562 ENCFF226VMS 216 bp overlap

FOSL1 3 datasets

ChIP K562 ENCFF455MKD 190 bp overlap

ChIP K562 ENCFF455MKD 186 bp overlap

ChIP K562 ENCFF728OTE 163 bp overlap

GATA2 2 datasets

ChIP K562 ENCFF088XQT 274 bp overlap

ChIP K562 ENCFF544PCK 162 bp overlap

GATA4 1 dataset

ChIP DE DE-GATA4-2 315 bp overlap

GATA6 6 datasets

ChIP DE DE-GATA6-1 282 bp overlap

ChIP DE DE-GATA6-2 289 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 409 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 392 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 458 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 212 bp overlap

GATAD2B 1 dataset

ChIP K562 ENCFF696VMK 250 bp overlap

GMEB1 1 dataset

ChIP K562 ENCFF705LHX 382 bp overlap

HAND2 1 dataset

Motif DE_12h DE_12h-HAND2_MA1638.2 6 bp overlap

HDAC1 1 dataset

ChIP K562 ENCFF928TKZ 260 bp overlap

HDAC2 1 dataset

ChIP K562 ENCFF744ALD 169 bp overlap

Motif DE_12h DE_12h-HIC2_MA0738.2 6 bp overlap

Hnf1A 1 dataset

Motif DE_12h DE_12h-Hnf1A_MA1991.2 10 bp overlap

IKZF1 1 dataset

ChIP K562 ENCFF771OHZ 340 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 458 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 458 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 440 bp overlap

ChIP DE_D2 S54-DE-d2-JUN-exp2 406 bp overlap

ChIP ESC S34-ESC-d0-JUN-exp2 275 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 179 bp overlap

JUNB 2 datasets

ChIP K562 ENCFF388SEP 261 bp overlap

ChIP K562 ENCFF785CFE 254 bp overlap

JUND 2 datasets

ChIP K562 ENCFF336RCR 278 bp overlap

ChIP K562 ENCFF830LVJ 186 bp overlap

KDM1A 2 datasets

ChIP K562 ENCFF128TYE 313 bp overlap

ChIP K562 ENCFF133OLU 315 bp overlap

ChIP K562 ENCFF455EEO 257 bp overlap

MAFK 2 datasets

ChIP H1 ENCFF854XWE 192 bp overlap

ChIP K562 ENCFF380WHM 186 bp overlap

ChIP hESC_PRIMED GSE69646.MED1.hESC_PRIMED 104 bp overlap

MEIS1 1 dataset

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

ChIP K562 ENCFF140CEX 260 bp overlap

ChIP K562 ENCFF820IGH 379 bp overlap

MORC2 1 dataset

ChIP H9 GSE95374.MORC2.H9 77 bp overlap

ChIP K562 ENCFF880VZB 142 bp overlap

NANOG 6 datasets

ChIP GM23338 ENCFF065NZG 311 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 233 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 180 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 187 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 174 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 158 bp overlap

NCOA1 1 dataset

ChIP K562 ENCFF962VHQ 165 bp overlap

NCOR1 2 datasets

ChIP K562 ENCFF788MPU 172 bp overlap

ChIP K562 ENCFF866HRM 218 bp overlap

NEUROD1 1 dataset

Motif DE_12h DE_12h-NEUROD1_MA1109.2 8 bp overlap

NEUROG2 1 dataset

Motif DE_12h DE_12h-NEUROG2_MA1642.2 7 bp overlap

NFE2 2 datasets

ChIP K562 ENCFF047YKA 246 bp overlap

ChIP K562 ENCFF163BSI 185 bp overlap

ChIP K562 ENCFF167YID 176 bp overlap

NR2F1 1 dataset

Motif DE_12h DE_12h-NR2F1_MA0017.3 12 bp overlap

Neurod2 1 dataset

Motif DE_12h DE_12h-Neurod2_MA0668.3 8 bp overlap

Nr1h3::Rxra 1 dataset

Motif DE_12h DE_12h-Nr1h3Rxra_MA0494.2 16 bp overlap

Nr2F6 1 dataset

Motif DE_12h DE_12h-Nr2F6_MA0728.1 15 bp overlap

ChIP K562 ENCFF217UCA 106 bp overlap

POLR2A 6 datasets

ChIP GM23338 ENCFF450WCS 141 bp overlap

ChIP GM23338 ENCFF450WCS 294 bp overlap

ChIP H1 ENCFF566JSR 138 bp overlap

ChIP H1 ENCFF770YBQ 279 bp overlap

ChIP K562 ENCFF514URW 237 bp overlap

ChIP K562 ENCFF836GHX 312 bp overlap

POU5F1 3 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 429 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 197 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 103 bp overlap

RBFOX2 1 dataset

ChIP K562 ENCFF967GRF 339 bp overlap

ChIP K562 ENCFF653BQJ 264 bp overlap

Motif DE_12h DE_12h-Rarg_MA0859.2 15 bp overlap

SIN3A 2 datasets

ChIP H1 ENCFF042ZSL 254 bp overlap

ChIP WA01 ENCSR000EBO.SIN3A.WA01 84 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 208 bp overlap

SMAD2_3 4 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 268 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 351 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 458 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 377 bp overlap

SMARCA4 2 datasets

ChIP K562 ENCFF316MCJ 223 bp overlap

ChIP K562 ENCFF506JCB 301 bp overlap

SMARCC2 1 dataset

ChIP K562 ENCFF368GSR 191 bp overlap

SMARCE1 2 datasets

ChIP K562 ENCFF690CFF 290 bp overlap

ChIP K562 ENCFF690CFF 290 bp overlap

ChIP K562 ENCFF059YCJ 279 bp overlap

Motif DE_12h DE_12h-SPIB_MA0081.3 13 bp overlap

TAF1 2 datasets

ChIP H1 ENCFF478SZO 294 bp overlap

ChIP H1 ENCFF478SZO 70 bp overlap

TAL1 2 datasets

ChIP K562 ENCFF620GMX 202 bp overlap

ChIP K562 ENCFF661CCK 165 bp overlap

ChIP H1 ENCFF859IIO 365 bp overlap

ChIP H1 ENCFF859IIO 162 bp overlap

ChIP WA01 ENCSR000ECB.TBP.WA01 86 bp overlap

ChIP hESC_10h GSE122298.TBP.hESC_10h 89 bp overlap

TCF12 2 datasets

ChIP K562 ENCFF909RDY 128 bp overlap

ChIP K562 ENCFF931DJY 268 bp overlap

ChIP K562 ENCFF319QZT 154 bp overlap

TCF7L2 1 dataset

Motif DE_12h DE_12h-TCF7L2_MA0523.2 9 bp overlap

TEAD4 2 datasets

ChIP ESC S26-ESC-d0-TEAD4-exp1 300 bp overlap

ChIP K562 ENCFF673NIK 95 bp overlap

TFAP2C 1 dataset

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 124 bp overlap

Motif DE_12h DE_12h-THRA_MA1969.2 18 bp overlap

TRIM24 2 datasets

ChIP K562 ENCFF284DKY 255 bp overlap

ChIP K562 ENCFF616RIL 115 bp overlap

TWIST1 1 dataset

Motif DE_12h DE_12h-TWIST1_MA1123.3 8 bp overlap

Motif DE_12h DE_12h-Wt1_MA1627.2 10 bp overlap

ZBTB2 1 dataset

ChIP K562 ENCFF290ESQ 220 bp overlap

ZBTB40 1 dataset

ChIP K562 ENCFF521DSV 197 bp overlap

ZEB2 2 datasets

ChIP K562 ENCFF795CMH 169 bp overlap

ChIP K562 ENCFF975RXS 356 bp overlap

Motif DE_12h DE_12h-ZIC1_MA0696.1 14 bp overlap

Motif DE_12h DE_12h-ZIC4_MA0751.2 14 bp overlap

Motif DE_12h DE_12h-ZIC5_MA1584.2 15 bp overlap

ZNF281 1 dataset

ChIP K562 ENCFF594VNM 282 bp overlap

ZNF316 1 dataset

ChIP K562 ENCFF838QCD 220 bp overlap

ZNF416 1 dataset

Motif DE_12h DE_12h-ZNF416_MA1979.2 10 bp overlap

ZNF449 1 dataset

Motif DE_12h DE_12h-ZNF449_MA1656.2 10 bp overlap

ZNF454 1 dataset

Motif DE_12h DE_12h-ZNF454_MA1712.2 17 bp overlap

ZNF528 1 dataset

Motif DE_12h DE_12h-ZNF528_MA1597.1 17 bp overlap

ZNF707 2 datasets

Motif DE_12h DE_12h-ZNF707_MA1715.1 15 bp overlap

Motif DE_12h DE_12h-ZNF707_MA1715.1 15 bp overlap

Zfp335 1 dataset

Motif DE_12h DE_12h-Zfp335_MA2002.2 7 bp overlap