chr19:3,441,686–3,442,206

chr19 : 3,441,686 – 3,442,206

520 bp 86 TFs 9 linked genes

This 520 bp open chromatin element is linked to 9 target genes and is bound by 86 transcription factors.

Linked Genes

9 genes

Gene	Expression	Dist. to TSS	Distance	Link type
NFIC		6.6 kb	Proximal	Proximity
DOHH		58.7 kb	Distal	Multiome
FZR1		64.4 kb	Distal	Multiome
MFSD12		115.6 kb	Distal	Multiome
HMG20B		131.0 kb	Distal	Multiome
CACTIN		184.8 kb	Distal	Multiome
CELF5		217.3 kb	Distal	Multiome
NCLN		256.0 kb	Distal	Multiome
PIP5K1C		258.5 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

86 transcription factors

ARID1A 1 dataset

ChIP H9 GSE139260.ARID1A.H9 161 bp overlap

ChIP metastatic-neuroblastoma_SKNMM GSE100148.ATRX.metastatic-neuroblastoma_SKNMM 271 bp overlap

ChIP SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour ENCSR754GYI.BNC2.SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour 259 bp overlap

BRD4 9 datasets

ChIP Kelly_resistant GSE103030.BRD4.Kelly_resistant 189 bp overlap

ChIP Kelly_resistant_JQ1 GSE103030.BRD4.Kelly_resistant_JQ1 160 bp overlap

ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 310 bp overlap

ChIP MDA-MB-157 ERP003925.BRD4.MDA-MB-157 183 bp overlap

ChIP SK-N-BE2-C_Naive-veh GSE107706.BRD4.SK-N-BE2-C_Naive-veh 315 bp overlap

ChIP SK-N-BE2-C_Resistant-veh GSE107706.BRD4.SK-N-BE2-C_Resistant-veh 369 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 520 bp overlap

ChIP retina_AB1-FW20 GSE86981.BRD4.retina_AB1-FW20 520 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 520 bp overlap

ChIP H9_Activin GSE94418.BRF1.H9_Activin 141 bp overlap

ChIP ME-1 GSE46044.CBFB.ME-1 176 bp overlap

CDKN1B 1 dataset

ChIP MDA-MB-231 GSE112444.CDKN1B.MDA-MB-231 101 bp overlap

CHD2 2 datasets

ChIP SK-N-SH ENCFF669KMB 361 bp overlap

ChIP SK-N-SH ENCSR274SLQ.CHD2.SK-N-SH 288 bp overlap

ChIP retina_Hu6 GSE137311.CRX.retina_Hu6 392 bp overlap

ChIP Kelly_sensitive GSE103030.CTCF.Kelly_sensitive 159 bp overlap

ChIP HeLa-S3 ENCSR219MKK.DEK.HeLa-S3 77 bp overlap

EBF3_P177L 1 dataset

ChIP SK-N-SH GSE90682.EBF3_P177L.SK-N-SH 417 bp overlap

ChIP HEK293 ENCFF336LFH 227 bp overlap

ChIP GM12878 ENCSR000BMB.ELF1.GM12878 253 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 150 bp overlap

EP300 2 datasets

ChIP SK-N-SH ENCFF829RWA 377 bp overlap

ChIP SK-N-SH ENCSR000EHV.EP300.SK-N-SH 313 bp overlap

ChIP Ishikawa_DMSO_D538G_clone3 GSE132426.ESR1.Ishikawa_DMSO_D538G_clone3 309 bp overlap

ETS1 5 datasets

ChIP HUVEC-C_4h GSE93030.ETS1.HUVEC-C_4h 173 bp overlap

ChIP HUVEC-C_VEGF_4H GSE41166.ETS1.HUVEC-C_VEGF_4H 173 bp overlap

ChIP HUVEC-C_VEGF_4h GSE109625.ETS1.HUVEC-C_VEGF_4h 173 bp overlap

ChIP K-562 ENCSR000BKQ.ETS1.K-562 52 bp overlap

ChIP cardiomyocyte_D2 GSE129986.ETS1.cardiomyocyte_D2 520 bp overlap

FIP1L1 1 dataset

ChIP Hep-G2 ENCSR313VZG.FIP1L1.Hep-G2 85 bp overlap

FLI1 4 datasets

ChIP A-673_1_KRAB_GFP GSE106914.FLI1.A-673_1_KRAB_GFP 277 bp overlap

ChIP A-673_2_KRAB_eSOX2_1 GSE106914.FLI1.A-673_2_KRAB_eSOX2_1 252 bp overlap

ChIP A-673_D14 GSE129155.FLI1.A-673_D14 234 bp overlap

ChIP A-673_D17 GSE129155.FLI1.A-673_D17 298 bp overlap

FOXA2 1 dataset

ChIP BJ1-hTERT_FoxHnf1aCoExp GSE90454.FOXA2.BJ1-hTERT_FoxHnf1aCoExp 344 bp overlap

FOXJ3 1 dataset

ChIP SK-N-SH ENCFF124KVL 441 bp overlap

FOXP2 2 datasets

ChIP PFSK-1 ENCFF349WGE 301 bp overlap

ChIP PFSK1 ENCSR000BGA.FOXP2.PFSK1 177 bp overlap

GATA2 1 dataset

ChIP SK-N-SH ENCFF764OZD 417 bp overlap

GATA6 4 datasets

ChIP DE_D1 S41-DE-d1-GATA6-exp2 461 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 324 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 392 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 446 bp overlap

GLIS3 3 datasets

ChIP H9_plus GSE109562.GLIS3.H9_plus 140 bp overlap

ChIP SK-N-SH ENCFF370MHZ 274 bp overlap

ChIP SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour ENCSR507BWM.GLIS3.SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour 274 bp overlap

HAND2 2 datasets

ChIP CLB-Ga GSE90683.HAND2.CLB-Ga 380 bp overlap

ChIP SK-N-BE2-C GSE94822.HAND2.SK-N-BE2-C 352 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 55 bp overlap

ChIP HEK293 ENCSR803GYT.HIC1.HEK293 313 bp overlap

HNRNPLL 1 dataset

ChIP Hep-G2 ENCSR804HMZ.HNRNPLL.Hep-G2 172 bp overlap

ChIP 786-O GSE86092.JUN.786-O 95 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 305 bp overlap

KDM1A 2 datasets

ChIP SH-SY5Y_B0_SHLSD18A GSE58258.KDM1A.SH-SY5Y_B0_SHLSD18A 180 bp overlap

ChIP SH-SY5Y_B3 GSE58258.KDM1A.SH-SY5Y_B3 182 bp overlap

KDM6B 1 dataset

ChIP CUTLL1 GSE56694.KDM6B.CUTLL1 84 bp overlap

ChIP CCRF-CEM GSE33850.LMO2.CCRF-CEM 139 bp overlap

ChIP HUVEC-C_siERG GSE124892.MED1.HUVEC-C_siERG 408 bp overlap

MYCN 6 datasets

ChIP COG-N-415 GSE138295.MYCN.COG-N-415 520 bp overlap

ChIP Kelly GSE94782.MYCN.Kelly 71 bp overlap

ChIP Kelly GSE94822.MYCN.Kelly 150 bp overlap

ChIP Kelly GSE94782.MYCN.Kelly 146 bp overlap

ChIP LA-N-5 GSE138295.MYCN.LA-N-5 466 bp overlap

ChIP NB-1643 GSE138295.MYCN.NB-1643 460 bp overlap

MYOD1 1 dataset

ChIP IMR-90_GM GSE128527.MYOD1.IMR-90_GM 69 bp overlap

NCAPH2 1 dataset

ChIP IMR-90_FLAG_OIS GSE118494.NCAPH2.IMR-90_FLAG_OIS 366 bp overlap

NEUROD1 1 dataset

ChIP D341-Med_shNEUROD1-1579 GSE92582.NEUROD1.D341-Med_shNEUROD1-1579 269 bp overlap

NKX2-1 1 dataset

ChIP H9_derived-cIN GSE99937.NKX2-1.H9_derived-cIN 139 bp overlap

NR4A1 1 dataset

ChIP Kasumi-1 GSE79491.NR4A1.Kasumi-1 183 bp overlap

ChIP HEK293 GSE89017.OGG1.HEK293 195 bp overlap

PARP1 1 dataset

ChIP MCF-10A GSE93038.PARP1.MCF-10A 268 bp overlap

PATZ1 1 dataset

ChIP SK-N-SH ENCFF650NCN 365 bp overlap

PCBP1 1 dataset

ChIP K-562 ENCSR052PTN.PCBP1.K-562 160 bp overlap

PHOX2B 2 datasets

ChIP CLB-Ga GSE90683.PHOX2B.CLB-Ga 410 bp overlap

ChIP SK-N-BE2-C GSE94822.PHOX2B.SK-N-BE2-C 224 bp overlap

PITX3 1 dataset

ChIP SH-SY5Y GSE93275.PITX3.SH-SY5Y 389 bp overlap

PLAG1 2 datasets

ChIP K-562 GSE111469.PLAG1.K-562 90 bp overlap

ChIP K-562 GSE111469.PLAG1.K-562 141 bp overlap

POLR2A 2 datasets

ChIP spleen ENCFF706IUS 188 bp overlap

ChIP vagina ENCFF384GAB 128 bp overlap

POLR2G 2 datasets

ChIP K562 ENCFF047BLG 436 bp overlap

ChIP K562 ENCFF648YPL 436 bp overlap

POU5F1 2 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 520 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 137 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 520 bp overlap

RBM22 6 datasets

ChIP HepG2 ENCFF292RVQ 270 bp overlap

ChIP HepG2 ENCFF561IAJ 271 bp overlap

ChIP K-562 GSE120104.RBM22.K-562 520 bp overlap

ChIP K-562 ENCSR848AOP.RBM22.K-562 520 bp overlap

ChIP K562 ENCFF420JDS 328 bp overlap

ChIP K562 ENCFF629OUL 324 bp overlap

RBM39 1 dataset

ChIP Hep-G2 ENCSR339JTP.RBM39.Hep-G2 160 bp overlap

RCOR1 2 datasets

ChIP SK-N-SH ENCFF518EXB 365 bp overlap

ChIP SK-N-SH ENCSR009TKN.RCOR1.SK-N-SH 291 bp overlap

ChIP HEK293_TNF-1h GSE75562.RELA.HEK293_TNF-1h 248 bp overlap

ChIP PFSK-1 ENCFF845VHA 321 bp overlap

ChIP retina_Hu22 GSE137311.RORB.retina_Hu22 220 bp overlap

RPA2_phospho 2 datasets

ChIP HeLa GSE108172.RPA2_phospho.HeLa 85 bp overlap

ChIP HeLa GSE108172.RPA2_phospho.HeLa 284 bp overlap

ChIP TSU-1621MT GSE60477.RXR.TSU-1621MT 171 bp overlap

SIRT6 1 dataset

ChIP SK-MEL-239_L-C-B GSE102813.SIRT6.SK-MEL-239_L-C-B 433 bp overlap

SMAD2 1 dataset

ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 380 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 437 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 520 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 520 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 502 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 485 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 520 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 447 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 471 bp overlap

SMARCB1 1 dataset

ChIP HeLa-S3 ENCSR000EDK.SMARCB1.HeLa-S3 188 bp overlap

ChIP SK-N-SH ENCFF791WFB 241 bp overlap

SNAI2 1 dataset

ChIP SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour ENCSR106GVM.SNAI2.SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour 169 bp overlap

SREBP2 1 dataset

ChIP HCC70 GSE126380.SREBP2.HCC70 198 bp overlap

STAT3 2 datasets

ChIP WA01 ERP004237.STAT3.WA01 93 bp overlap

ChIP WA01 ERP004237.STAT3.WA01 187 bp overlap

ChIP Kelly GSE94822.TBX2.Kelly 294 bp overlap

TEAD1 1 dataset

ChIP H69 GSE62274.TEAD1.H69 132 bp overlap

TEAD4 2 datasets

ChIP BE2C GSE84389.TEAD4.BE2C 264 bp overlap

ChIP SK-N-BE2 GSE84389.TEAD4.SK-N-BE2 264 bp overlap

TFAP2B 1 dataset

ChIP SK-N-SH ENCFF869XXQ 409 bp overlap

TFAP2C 1 dataset

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 258 bp overlap

ChIP breast-organoid GSE113909.TP63.breast-organoid 82 bp overlap

TRIM28 1 dataset

ChIP hESC GSE115387.TRIM28.hESC 181 bp overlap

TSHZ2 2 datasets

ChIP SK-N-SH ENCFF182EBB 346 bp overlap

ChIP SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour ENCSR282NLQ.TSHZ2.SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour 520 bp overlap

TWIST1 2 datasets

ChIP BE2C GSE80151.TWIST1.BE2C 170 bp overlap

ChIP SK-N-BE2-C GSE80151.TWIST1.SK-N-BE2-C 170 bp overlap

ChIP K-562 GSE111469.USF2.K-562 188 bp overlap

ChIP Huh-7 GSE97411.YY1.Huh-7 509 bp overlap

ZBTB33 4 datasets

ChIP HepG2 ENCFF778UKV 94 bp overlap

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 257 bp overlap

ChIP K562 ENCFF427SDV 277 bp overlap

ChIP K562 ENCFF875HLX 148 bp overlap

ZBTB48 1 dataset

ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 247 bp overlap

ZBTB7A 1 dataset

ChIP K-562 ENCSR000BME.ZBTB7A.K-562 219 bp overlap

ChIP SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour ENCSR581GUY.ZFP3.SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour 294 bp overlap

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 520 bp overlap

ZNF341 2 datasets

ChIP HEK293 ENCFF944VMC 227 bp overlap

ChIP HEK293 ENCSR185FOY.ZNF341.HEK293 188 bp overlap