chr17:36,612,842–36,614,639

chr17 : 36,612,842 – 36,614,639

1,797 bp 111 TFs 7 linked genes

This 1.8 kb open chromatin element is linked to 7 target genes and is bound by 111 transcription factors.

Linked Genes

7 genes

Gene	Expression	Dist. to TSS	Distance	Link type
GGNBP2		68.5 kb	Distal	Multiome
MYO19		78.5 kb	Distal	Multiome
ZNHIT3		126.7 kb	Distal	Multiome
LHX1-DT		323.3 kb	Distal	Multiome+HiCAR
LHX1		323.4 kb	Distal	Multiome+HiCAR
ACACA		793.4 kb	Distal	Multiome+HiCAR
TADA2A		793.5 kb	Distal	Multiome+HiCAR

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

111 transcription factors

ChIP HCT-116 GSE103894.APC.HCT-116 343 bp overlap

ChIP LNCaP-clone-FGC_DHT-ABBV-744 GSE118247.AR.LNCaP-clone-FGC_DHT-ABBV-744 133 bp overlap

ASCL1 1 dataset

Motif DE_72h DE_72h-ASCL1_MA1631.2 9 bp overlap

ASH2L 3 datasets

ChIP H1 ENCFF399KAM 785 bp overlap

ChIP H1 ENCFF399KAM 729 bp overlap

ChIP H1 ENCFF399KAM 527 bp overlap

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 181 bp overlap

BRCA1 1 dataset

ChIP SH-EP_pWZL-MYCNwt GSE111905.BRCA1.SH-EP_pWZL-MYCNwt 95 bp overlap

ChIP HUES-64 GSE104059.BRD1.HUES-64 239 bp overlap

CREB1 3 datasets

ChIP Hep-G2 ENCSR112ALD.CREB1.Hep-G2 271 bp overlap

ChIP HepG2 ENCFF792THT 391 bp overlap

ChIP MCF-7 ENCSR897JAS.CREB1.MCF-7 243 bp overlap

CTCF 4 datasets

Motif DE_48h DE_48h-CTCF_MA1930.2 33 bp overlap

Motif DE_72h DE_72h-CTCF_MA1930.2 33 bp overlap

ChIP endodermal cell ENCFF471YCZ 136 bp overlap

ChIP endodermal cell ENCFF471YCZ 461 bp overlap

Cebpa 2 datasets

ChIP BLaER1 ENCFF335XTP 289 bp overlap

ChIP BLaER1 ENCFF364PUR 384 bp overlap

DPRX 2 datasets

Motif DE_48h DE_48h-DPRX_MA1480.2 9 bp overlap

Motif DE_72h DE_72h-DPRX_MA1480.2 9 bp overlap

EGR3 2 datasets

Motif DE_48h DE_48h-EGR3_MA0732.2 11 bp overlap

Motif DE_72h DE_72h-EGR3_MA0732.2 11 bp overlap

EOMES 2 datasets

Motif DE_72h DE_72h-EOMES_MA0800.2 9 bp overlap

ChIP hESC GSE26097.EOMES.hESC 132 bp overlap

ChIP Ishikawa_DMSO_D538G_clone3 GSE132426.ESR1.Ishikawa_DMSO_D538G_clone3 217 bp overlap

ETS1 2 datasets

ChIP cardiomyocyte_D2 GSE129986.ETS1.cardiomyocyte_D2 288 bp overlap

ChIP cardiomyocyte_D2 GSE129986.ETS1.cardiomyocyte_D2 904 bp overlap

EZH2 2 datasets

ChIP endothelial cell of umbilical vein ENCFF539AKL 925 bp overlap

ChIP endothelial cell of umbilical vein ENCFF539AKL 925 bp overlap

FIGLA 2 datasets

Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap

Motif DE_72h DE_72h-FIGLA_MA0820.2 6 bp overlap

FOXA1 1 dataset

ChIP LS180 GSE140533.FOXA1.LS180 114 bp overlap

FOXA2 3 datasets

ChIP DE DE-FOXA2-1 1413 bp overlap

ChIP DE DE-FOXA2-2 752 bp overlap

ChIP DE DE-FOXA2-2 536 bp overlap

FOXK1 3 datasets

ChIP WTC11 ENCFF875IGU 391 bp overlap

ChIP WTC11 ENCFF875IGU 391 bp overlap

ChIP WTC11 ENCFF875IGU 391 bp overlap

FOXP1 1 dataset

ChIP WTC11 ENCFF338WGC 525 bp overlap

FOXS1 1 dataset

Motif DE_72h DE_72h-FOXS1_MA2118.1 8 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 1414 bp overlap

ChIP DE DE-GATA4-2 1400 bp overlap

GATA6 13 datasets

ChIP DE DE-GATA6-1 493 bp overlap

ChIP DE DE-GATA6-1 782 bp overlap

ChIP DE DE-GATA6-2 1381 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 410 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 656 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 1288 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 583 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 683 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 1429 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 1464 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 613 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 702 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 1372 bp overlap

HOXB4 2 datasets

Motif DE_72h DE_72h-HOXB4_MA1499.2 6 bp overlap

Motif DE_72h DE_72h-HOXB4_MA1499.2 6 bp overlap

HOXC4 2 datasets

Motif DE_72h DE_72h-HOXC4_MA1504.2 6 bp overlap

Motif DE_72h DE_72h-HOXC4_MA1504.2 6 bp overlap

HOXD4 2 datasets

Motif DE_72h DE_72h-HOXD4_MA1507.2 6 bp overlap

Motif DE_72h DE_72h-HOXD4_MA1507.2 6 bp overlap

HSF1 2 datasets

Motif DE_48h DE_48h-HSF1_MA0486.2 13 bp overlap

Motif DE_72h DE_72h-HSF1_MA0486.2 13 bp overlap

HSF2 2 datasets

Motif DE_48h DE_48h-HSF2_MA0770.1 13 bp overlap

Motif DE_72h DE_72h-HSF2_MA0770.1 13 bp overlap

HSF4 2 datasets

Motif DE_48h DE_48h-HSF4_MA0771.1 13 bp overlap

Motif DE_72h DE_72h-HSF4_MA0771.1 13 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 279 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 386 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 647 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 601 bp overlap

ChIP DE_D2 S54-DE-d2-JUN-exp2 313 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 307 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 340 bp overlap

KDM1A 2 datasets

ChIP A-549 ENCSR639GWS.KDM1A.A-549 103 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.KDM1A.pancreatic-progenitor_PP1 230 bp overlap

MEIS1 4 datasets

Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap

Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap

Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap

Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap

Motif DE_72h DE_72h-MGA_MA0801.1 8 bp overlap

MGA::EVX1 1 dataset

Motif DE_72h DE_72h-MGAEVX1_MA1960.2 11 bp overlap

MYOD1 1 dataset

Motif DE_72h DE_72h-MYOD1_MA0499.3 9 bp overlap

NANOG 1 dataset

ChIP WA01 ENCSR000BMT.NANOG.WA01 117 bp overlap

NCAPH2 1 dataset

ChIP IMR-90_FLAG_OIS GSE118494.NCAPH2.IMR-90_FLAG_OIS 203 bp overlap

Motif DE_72h DE_72h-NFIB_MA1643.2 17 bp overlap

Motif DE_72h DE_72h-NFIC_MA1527.2 15 bp overlap

NFIC::TLX1 1 dataset

Motif DE_72h DE_72h-NFICTLX1_MA0119.1 14 bp overlap

Motif DE_72h DE_72h-NFIX_MA1528.2 14 bp overlap

NKX6-1 1 dataset

Motif DE_72h DE_72h-NKX6-1_MA0674.2 7 bp overlap

NR2C2 1 dataset

Motif DE_72h DE_72h-NR2C2_MA0504.2 14 bp overlap

ChIP HCT-116_ab20662 GSE97527.PAF1.HCT-116_ab20662 258 bp overlap

PDX1 3 datasets

ChIP hiPSC GSE125768.PDX1.hiPSC 355 bp overlap

ChIP hiPSC_derived_PPs GSE106949.PDX1.hiPSC_derived_PPs 239 bp overlap

ChIP pancreatic-progenitor GSE117136.PDX1.pancreatic-progenitor 324 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 1450 bp overlap

POU5F1_M 2 datasets

ChIP DE_D1 DED1-OCT4-M_Batch_II 524 bp overlap

ChIP DE_D1 DED1-OCT4-M_Batch_II 289 bp overlap

POU6F1 1 dataset

Motif DE_72h DE_72h-POU6F1_MA1549.2 7 bp overlap

POU6F2 1 dataset

Motif DE_72h DE_72h-POU6F2_MA0793.2 9 bp overlap

PPARA::RXRA 1 dataset

Motif DE_72h DE_72h-PPARARXRA_MA1148.2 17 bp overlap

PRDM10 3 datasets

ChIP HEK293 ENCFF145WQQ 261 bp overlap

ChIP K-562 ENCSR120MPG.PRDM10.K-562 205 bp overlap

ChIP K562 ENCFF740YLK 340 bp overlap

PRDM15 1 dataset

ChIP WTC11 ENCFF108TMF 385 bp overlap

PRDM9 1 dataset

Motif DE_72h DE_72h-PRDM9_MA1723.2 20 bp overlap

RBM25 5 datasets

ChIP K-562 ENCSR791OZM.RBM25.K-562 256 bp overlap

ChIP K562 ENCFF248CGR 99 bp overlap

ChIP K562 ENCFF248CGR 361 bp overlap

ChIP K562 ENCFF957ORK 97 bp overlap

ChIP K562 ENCFF957ORK 361 bp overlap

REST 2 datasets

ChIP H1 ENCFF429RUE 245 bp overlap

ChIP WA01 ENCSR000BHM.REST.WA01 195 bp overlap

RPA2_phospho 1 dataset

ChIP HeLa_shASF GSE108172.RPA2_phospho.HeLa_shASF 194 bp overlap

SMAD2-3 4 datasets

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 1332 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 418 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 499 bp overlap

ChIP HUVEC-C_TGFB1 GSE134556.SMAD2-3.HUVEC-C_TGFB1 548 bp overlap

SMAD2_3 6 datasets

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 333 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 379 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 461 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 496 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 1519 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 1369 bp overlap

SMARCA4 4 datasets

ChIP HS-SY-2_HA-tagged GSE108926.SMARCA4.HS-SY-2_HA-tagged 108 bp overlap

ChIP HS-SY-2_HA-tagged GSE108926.SMARCA4.HS-SY-2_HA-tagged 294 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 510 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 246 bp overlap

SMARCB1 1 dataset

ChIP hiPSC GSE124903.SMARCB1.hiPSC 366 bp overlap

SMARCC1 1 dataset

ChIP hiPSC GSE124903.SMARCC1.hiPSC 233 bp overlap

SOX17 2 datasets

ChIP DE_D2 DED2-SOX17_Batch_II 269 bp overlap

ChIP DE_D2 DED2-SOX17_Batch_II 297 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 1379 bp overlap

Motif DE_48h DE_48h-SP1_MA0079.5 9 bp overlap

Motif DE_48h DE_48h-SP1_MA0079.5 9 bp overlap

Motif DE_60h DE_60h-SP1_MA0079.5 9 bp overlap

Motif DE_72h DE_72h-SP1_MA0079.5 9 bp overlap

Motif DE_72h DE_72h-SP1_MA0079.5 9 bp overlap

Motif DE_48h DE_48h-SP4_MA0685.2 9 bp overlap

Motif DE_48h DE_48h-SP4_MA0685.2 9 bp overlap

Motif DE_60h DE_60h-SP4_MA0685.2 9 bp overlap

Motif DE_72h DE_72h-SP4_MA0685.2 9 bp overlap

Motif DE_72h DE_72h-SP4_MA0685.2 9 bp overlap

Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap

Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap

Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap

Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap

Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap

Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap

Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap

SUPT5H 1 dataset

ChIP DLD-1_NELFCD-AID GSE144786.SUPT5H.DLD-1_NELFCD-AID 361 bp overlap

Motif DE_72h DE_72h-TBR1_MA0802.2 9 bp overlap

TBX1 4 datasets

Motif DE_48h DE_48h-TBX1_MA0805.1 8 bp overlap

Motif DE_60h DE_60h-TBX1_MA0805.1 8 bp overlap

Motif DE_72h DE_72h-TBX1_MA0805.1 8 bp overlap

Motif DE_72h DE_72h-TBX1_MA0805.1 8 bp overlap

TBX15 4 datasets

Motif DE_48h DE_48h-TBX15_MA0803.1 8 bp overlap

Motif DE_60h DE_60h-TBX15_MA0803.1 8 bp overlap

Motif DE_72h DE_72h-TBX15_MA0803.1 8 bp overlap

Motif DE_72h DE_72h-TBX15_MA0803.1 8 bp overlap

TBX18 4 datasets

Motif DE_48h DE_48h-TBX18_MA1565.2 9 bp overlap

Motif DE_60h DE_60h-TBX18_MA1565.2 9 bp overlap

Motif DE_72h DE_72h-TBX18_MA1565.2 9 bp overlap

Motif DE_72h DE_72h-TBX18_MA1565.2 9 bp overlap

TBX2 4 datasets

Motif DE_48h DE_48h-TBX2_MA0688.2 9 bp overlap

Motif DE_60h DE_60h-TBX2_MA0688.2 9 bp overlap

Motif DE_72h DE_72h-TBX2_MA0688.2 9 bp overlap

Motif DE_72h DE_72h-TBX2_MA0688.2 9 bp overlap

TBX20 1 dataset

Motif DE_72h DE_72h-TBX20_MA0689.1 11 bp overlap

TBX21 1 dataset

Motif DE_72h DE_72h-TBX21_MA0690.3 10 bp overlap

TBX3 4 datasets

Motif DE_48h DE_48h-TBX3_MA1566.3 9 bp overlap

Motif DE_60h DE_60h-TBX3_MA1566.3 9 bp overlap

Motif DE_72h DE_72h-TBX3_MA1566.3 9 bp overlap

Motif DE_72h DE_72h-TBX3_MA1566.3 9 bp overlap

TBX4 4 datasets

Motif DE_48h DE_48h-TBX4_MA0806.1 8 bp overlap

Motif DE_60h DE_60h-TBX4_MA0806.1 8 bp overlap

Motif DE_72h DE_72h-TBX4_MA0806.1 8 bp overlap

Motif DE_72h DE_72h-TBX4_MA0806.1 8 bp overlap

TBX5 4 datasets

Motif DE_48h DE_48h-TBX5_MA0807.1 8 bp overlap

Motif DE_60h DE_60h-TBX5_MA0807.1 8 bp overlap

Motif DE_72h DE_72h-TBX5_MA0807.1 8 bp overlap

Motif DE_72h DE_72h-TBX5_MA0807.1 8 bp overlap

TCF12 1 dataset

ChIP WA01 ENCSR000BIT.TCF12.WA01 174 bp overlap

Motif DE_72h DE_72h-TCF4_MA0830.3 8 bp overlap

TEAD1 1 dataset

ChIP H69 GSE62274.TEAD1.H69 151 bp overlap

THAP1 2 datasets

Motif DE_72h DE_72h-THAP1_MA0597.3 8 bp overlap

ChIP K-562 ENCSR000BNN.THAP1.K-562 97 bp overlap

TOP2A 1 dataset

ChIP KG-1_etoposide GSE114048.TOP2A.KG-1_etoposide 101 bp overlap

Motif DE_72h DE_72h-TP63_MA0525.2 18 bp overlap

Motif DE_72h DE_72h-Tbx6_MA1567.3 9 bp overlap

Motif DE_48h DE_48h-USF1_MA0093.4 10 bp overlap

VEZF1 1 dataset

Motif DE_72h DE_72h-VEZF1_MA1578.2 6 bp overlap

Motif DE_48h DE_48h-Wt1_MA1627.2 10 bp overlap

Motif DE_72h DE_72h-Wt1_MA1627.2 10 bp overlap

ZBTB26 2 datasets

Motif DE_48h DE_48h-ZBTB26_MA1579.2 8 bp overlap

Motif DE_72h DE_72h-ZBTB26_MA1579.2 8 bp overlap

ZBTB7A 2 datasets

ChIP K-562 GSE103445.ZBTB7A.K-562 208 bp overlap

ChIP K-562 ENCSR000BME.ZBTB7A.K-562 94 bp overlap

ZBTB7B 1 dataset

Motif DE_72h DE_72h-ZBTB7B_MA0694.2 10 bp overlap

ZEB1 2 datasets

Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap

Motif DE_72h DE_72h-ZEB1_MA0103.4 6 bp overlap

ZKSCAN5 2 datasets

Motif DE_48h DE_48h-ZKSCAN5_MA1652.2 9 bp overlap

Motif DE_72h DE_72h-ZKSCAN5_MA1652.2 9 bp overlap

ZNF148 8 datasets

Motif DE_48h DE_48h-ZNF148_MA1653.2 10 bp overlap

Motif DE_48h DE_48h-ZNF148_MA1653.2 10 bp overlap

Motif DE_60h DE_60h-ZNF148_MA1653.2 10 bp overlap

Motif DE_72h DE_72h-ZNF148_MA1653.2 10 bp overlap

Motif DE_72h DE_72h-ZNF148_MA1653.2 10 bp overlap

Motif DE_72h DE_72h-ZNF148_MA1653.2 10 bp overlap

Motif DE_72h DE_72h-ZNF148_MA1653.2 10 bp overlap

ChIP K-562 GSE121133.ZNF148.K-562 281 bp overlap

ZNF263 1 dataset

ChIP K-562 ENCSR000EWN.ZNF263.K-562 245 bp overlap

ZNF281 7 datasets

Motif DE_48h DE_48h-ZNF281_MA1630.3 10 bp overlap

Motif DE_48h DE_48h-ZNF281_MA1630.3 10 bp overlap

Motif DE_60h DE_60h-ZNF281_MA1630.3 10 bp overlap

Motif DE_72h DE_72h-ZNF281_MA1630.3 10 bp overlap

Motif DE_72h DE_72h-ZNF281_MA1630.3 10 bp overlap

Motif DE_72h DE_72h-ZNF281_MA1630.3 10 bp overlap

Motif DE_72h DE_72h-ZNF281_MA1630.3 10 bp overlap

ZNF341 2 datasets

ChIP HEK293 ENCFF944VMC 521 bp overlap

ChIP HEK293 ENCSR185FOY.ZNF341.HEK293 562 bp overlap

ZNF454 1 dataset

Motif DE_72h DE_72h-ZNF454_MA1712.2 17 bp overlap

ZNF467 1 dataset

ChIP HEK293 GSE76494.ZNF467.HEK293 231 bp overlap

ZNF513 2 datasets

ChIP HEK293 ENCFF457TCC 183 bp overlap

ChIP HEK293 ENCSR503DPC.ZNF513.HEK293 389 bp overlap

ZNF530 2 datasets

Motif DE_72h DE_72h-ZNF530_MA1981.2 14 bp overlap

Motif DE_72h DE_72h-ZNF530_MA1981.2 14 bp overlap

ZNF547 1 dataset

Motif DE_72h DE_72h-ZNF547_MA2334.1 13 bp overlap

ZNF664 2 datasets

ChIP HEK293 ENCFF343XSW 385 bp overlap

ChIP HEK293 ENCSR714LZQ.ZNF664.HEK293 280 bp overlap

ZNF682 1 dataset

Motif DE_72h DE_72h-ZNF682_MA1599.2 11 bp overlap

ZNF701 1 dataset

Motif DE_72h DE_72h-ZNF701_MA1987.2 17 bp overlap

ZNF707 2 datasets

Motif DE_48h DE_48h-ZNF707_MA1715.1 15 bp overlap

Motif DE_72h DE_72h-ZNF707_MA1715.1 15 bp overlap

ZNF770 2 datasets

Motif DE_48h DE_48h-ZNF770_MA2099.1 8 bp overlap

Motif DE_72h DE_72h-ZNF770_MA2099.1 8 bp overlap

Zfp961 2 datasets

Motif DE_48h DE_48h-Zfp961_MA2126.1 8 bp overlap

Motif DE_72h DE_72h-Zfp961_MA2126.1 8 bp overlap

Zic1::Zic2 2 datasets

Motif DE_48h DE_48h-Zic1Zic2_MA1628.2 7 bp overlap

Motif DE_72h DE_72h-Zic1Zic2_MA1628.2 7 bp overlap

Zic2 2 datasets

Motif DE_48h DE_48h-Zic2_MA1629.2 9 bp overlap

Motif DE_72h DE_72h-Zic2_MA1629.2 9 bp overlap

Zic3 2 datasets

Motif DE_48h DE_48h-Zic3_MA0697.3 7 bp overlap

Motif DE_72h DE_72h-Zic3_MA0697.3 7 bp overlap