chr14 : 40,347,773 – 40,348,829

1,056 bp 108 TFs 1 linked gene

This 1.1 kb open chromatin element is linked to ENSG00000286123 and is bound by 108 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000286123		at TSS	At TSS	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

108 transcription factors

AR 2 datasets

ChIP LNCaP_G87R_shFOXA1_Ethanol GSE128883.AR.LNCaP_G87R_shFOXA1_Ethanol 157 bp overlap

ChIP LNCaP_GFP_shFOXA1_Ethanol GSE128883.AR.LNCaP_GFP_shFOXA1_Ethanol 205 bp overlap

ASCL1 1 dataset

Motif DE_48h DE_48h-ASCL1_MA1631.2 9 bp overlap

ASH2L 2 datasets

ChIP H1 ENCFF399KAM 785 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 345 bp overlap

BRD2 4 datasets

ChIP HCC1806_BAZ2B_JQ1 GSE116879.BRD2.HCC1806_BAZ2B_JQ1 334 bp overlap

ChIP HCC1806_BAZ2BsiRNA GSE116879.BRD2.HCC1806_BAZ2BsiRNA 370 bp overlap

ChIP HCC1806_NTsiRNA GSE116879.BRD2.HCC1806_NTsiRNA 395 bp overlap

ChIP HCC1806_NTsiRNA_JQ1 GSE116879.BRD2.HCC1806_NTsiRNA_JQ1 295 bp overlap

BRD4 7 datasets

ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 315 bp overlap

ChIP LNCaP-C4-2_F133V GSE88871.BRD4.LNCaP-C4-2_F133V 325 bp overlap

ChIP LNCaP-C4-2_F133V_JQ1 GSE88871.BRD4.LNCaP-C4-2_F133V_JQ1 285 bp overlap

ChIP LNCaP-C4-2_OE GSE88871.BRD4.LNCaP-C4-2_OE 309 bp overlap

ChIP T-47D_DMSO GSE63581.BRD4.T-47D_DMSO 408 bp overlap

ChIP cortical-interneuron_R133C_KCl-neg_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-neg_JQ1-neg 213 bp overlap

ChIP cortical-interneuron_R133C_KCl-pos_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-pos_JQ1-neg 269 bp overlap

CEBPA 1 dataset

ChIP T-47D_progesterone GSE132649.CEBPA.T-47D_progesterone 319 bp overlap

CREB1 2 datasets

ChIP LNCaP-abl_SHCTR GSE63034.CREB1.LNCaP-abl_SHCTR 308 bp overlap

ChIP LNCaP-abl_SHFOXA1 GSE63034.CREB1.LNCaP-abl_SHFOXA1 89 bp overlap

CSNK2A1 1 dataset

ChIP LNCaP_DHT GSE58607.CSNK2A1.LNCaP_DHT 222 bp overlap

CTCF 16 datasets

ChIP C4-2B ENCFF821XVN 614 bp overlap

Motif DE_12h DE_12h-CTCF_MA1929.2 31 bp overlap

Motif DE_12h DE_12h-CTCF_MA1930.2 33 bp overlap

Motif DE_48h DE_48h-CTCF_MA1929.2 31 bp overlap

Motif ES_0h ES_0h-CTCF_MA1929.2 31 bp overlap

ChIP HCT-116 GSE131606.CTCF.HCT-116 196 bp overlap

ChIP K-562_5635 GSE131349.CTCF.K-562_5635 106 bp overlap

ChIP LNCaP ENCSR000DMF.CTCF.LNCaP 105 bp overlap

ChIP LNCaP clone FGC ENCFF519YVI 181 bp overlap

ChIP LNCaP clone FGC ENCFF957KCI 181 bp overlap

ChIP LNCaP-C4-2B ENCSR460LGH.CTCF.LNCaP-C4-2B 277 bp overlap

ChIP T-47D GSE111923.CTCF.T-47D 310 bp overlap

ChIP T-47D GSE120162.CTCF.T-47D 146 bp overlap

ChIP T-47D_serum GSE120162.CTCF.T-47D_serum 147 bp overlap

ChIP T-47D_triptolide GSE111923.CTCF.T-47D_triptolide 301 bp overlap

ChIP hESC_NAIVE GSE69646.CTCF.hESC_NAIVE 214 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF844FIP 251 bp overlap

EGR1 3 datasets

Motif DE_12h DE_12h-EGR1_MA0162.5 10 bp overlap

Motif DE_48h DE_48h-EGR1_MA0162.5 10 bp overlap

Motif ES_0h ES_0h-EGR1_MA0162.5 10 bp overlap

ERF::NHLH1 1 dataset

Motif DE_48h DE_48h-ERFNHLH1_MA1938.2 16 bp overlap

ESR1 2 datasets

ChIP MCF-7_LTED GSE86538.ESR1.MCF-7_LTED 123 bp overlap

ChIP T-47D_Y537S_E2 GSE148277.ESR1.T-47D_Y537S_E2 283 bp overlap

ETS1 2 datasets

Motif DE_48h DE_48h-ETS1_MA0098.4 9 bp overlap

ChIP hESC ENCSR534VHI.ETS1.hESC 113 bp overlap

ETV2::DRGX 1 dataset

Motif DE_48h DE_48h-ETV2DRGX_MA1940.2 12 bp overlap

ETV5::HOXA2 1 dataset

Motif DE_48h DE_48h-ETV5HOXA2_MA1948.2 12 bp overlap

FIGLA 1 dataset

Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap

FLI1::DRGX 1 dataset

Motif DE_48h DE_48h-FLI1DRGX_MA1949.2 14 bp overlap

FOXA1 1 dataset

Motif DE_24h DE_24h-FOXA1_MA0148.5 8 bp overlap

FOXA2 3 datasets

ChIP DE DE-FOXA2-1 449 bp overlap

ChIP DE DE-FOXA2-2 441 bp overlap

Motif DE_24h DE_24h-FOXA2_MA0047.4 8 bp overlap

FOXA3 1 dataset

Motif DE_24h DE_24h-FOXA3_MA1683.2 7 bp overlap

FOXB1 1 dataset

Motif DE_24h DE_24h-FOXB1_MA0845.1 11 bp overlap

FOXC1 1 dataset

Motif DE_24h DE_24h-FOXC1_MA0032.2 11 bp overlap

FOXC2 1 dataset

Motif DE_24h DE_24h-FOXC2_MA0846.2 11 bp overlap

FOXD1 1 dataset

Motif DE_24h DE_24h-FOXD1_MA0031.2 7 bp overlap

FOXD2 1 dataset

Motif DE_24h DE_24h-FOXD2_MA0847.4 11 bp overlap

FOXD3 1 dataset

Motif DE_24h DE_24h-FOXD3_MA0041.3 14 bp overlap

FOXE1 1 dataset

Motif DE_24h DE_24h-FOXE1_MA1487.3 12 bp overlap

FOXF2 1 dataset

Motif DE_24h DE_24h-FOXF2_MA0030.2 9 bp overlap

FOXG1 1 dataset

Motif DE_24h DE_24h-FOXG1_MA0613.1 8 bp overlap

FOXI1 1 dataset

Motif DE_24h DE_24h-FOXI1_MA0042.2 7 bp overlap

FOXK1 1 dataset

Motif DE_24h DE_24h-FOXK1_MA0852.3 7 bp overlap

FOXK2 1 dataset

Motif DE_24h DE_24h-FOXK2_MA1103.3 7 bp overlap

FOXL1 1 dataset

Motif DE_24h DE_24h-FOXL1_MA0033.2 7 bp overlap

FOXN3 1 dataset

Motif DE_24h DE_24h-FOXN3_MA1489.1 8 bp overlap

FOXO4 1 dataset

Motif DE_24h DE_24h-FOXO4_MA0848.1 7 bp overlap

FOXO6 1 dataset

Motif DE_24h DE_24h-FOXO6_MA0849.1 7 bp overlap

FOXP1 1 dataset

Motif DE_24h DE_24h-FOXP1_MA0481.4 7 bp overlap

FOXP2 1 dataset

Motif DE_24h DE_24h-FOXP2_MA0593.2 9 bp overlap

FOXP3 1 dataset

Motif DE_24h DE_24h-FOXP3_MA0850.1 7 bp overlap

FOXP4 1 dataset

Motif DE_24h DE_24h-FOXP4_MA2117.1 7 bp overlap

FOXS1 1 dataset

Motif DE_24h DE_24h-FOXS1_MA2118.1 8 bp overlap

Foxf1 1 dataset

Motif DE_24h DE_24h-Foxf1_MA1606.2 7 bp overlap

Foxj2 1 dataset

Motif DE_24h DE_24h-Foxj2_MA0614.1 8 bp overlap

Foxj3 1 dataset

Motif DE_24h DE_24h-Foxj3_MA0851.2 9 bp overlap

Foxl2 1 dataset

Motif DE_24h DE_24h-Foxl2_MA1607.2 10 bp overlap

Foxo1 1 dataset

Motif DE_24h DE_24h-Foxo1_MA0480.3 7 bp overlap

Foxo3 1 dataset

Motif DE_24h DE_24h-Foxo3_MA0157.4 7 bp overlap

GATA3 1 dataset

ChIP T-47D ENCSR000BMX.GATA3.T-47D 109 bp overlap

GATA3_Nter 1 dataset

ChIP T-47D_CR3flp GSE99479.GATA3_Nter.T-47D_CR3flp 125 bp overlap

HOXB13 1 dataset

ChIP LNCaP GSE56288.HOXB13.LNCaP 118 bp overlap

HOXB2::ELK1 1 dataset

Motif DE_48h DE_48h-HOXB2ELK1_MA1957.1 14 bp overlap

Hand1::Tcf3 1 dataset

Motif DE_12h DE_12h-Hand1Tcf3_MA0092.2 9 bp overlap

INO80 1 dataset

ChIP Huh-7 GSE97411.INO80.Huh-7 327 bp overlap

KDM5A 2 datasets

ChIP T-47D_DMSO GSE80593.KDM5A.T-47D_DMSO 279 bp overlap

ChIP T-47D_MK2206 GSE80593.KDM5A.T-47D_MK2206 226 bp overlap

KLF11 3 datasets

Motif DE_12h DE_12h-KLF11_MA1512.2 10 bp overlap

Motif DE_48h DE_48h-KLF11_MA1512.2 10 bp overlap

Motif ES_0h ES_0h-KLF11_MA1512.2 10 bp overlap

KLF4 1 dataset

Motif DE_24h DE_24h-KLF4_MA0039.5 8 bp overlap

KLF5 1 dataset

Motif DE_24h DE_24h-KLF5_MA0599.1 10 bp overlap

MAF 3 datasets

Motif DE_12h DE_12h-MAF_MA1520.2 13 bp overlap

Motif DE_48h DE_48h-MAF_MA1520.2 13 bp overlap

Motif ES_0h ES_0h-MAF_MA1520.2 13 bp overlap

MED1 1 dataset

ChIP HCT-116 GSE121798.MED1.HCT-116 229 bp overlap

MED26 1 dataset

ChIP HCT-116_aux GSE121355.MED26.HCT-116_aux 447 bp overlap

MYB 1 dataset

Motif DE_12h DE_12h-MYB_MA0100.4 6 bp overlap

MYC 1 dataset

ChIP LNCaP_MYC GSE73994.MYC.LNCaP_MYC 115 bp overlap

MYCN 2 datasets

ChIP LNCaP_DHT GSE117304.MYCN.LNCaP_DHT 217 bp overlap

ChIP LNCaP_EtOH GSE117304.MYCN.LNCaP_EtOH 385 bp overlap

MYOD1 1 dataset

Motif DE_48h DE_48h-MYOD1_MA0499.3 9 bp overlap

NANOG 1 dataset

ChIP hESC GSE18292.NANOG.hESC 113 bp overlap

NR1D1 1 dataset

Motif DE_12h DE_12h-NR1D1_MA1531.2 14 bp overlap

NR1D2 1 dataset

Motif DE_12h DE_12h-NR1D2_MA1532.2 15 bp overlap

NR1I2 1 dataset

Motif DE_12h DE_12h-NR1I2_MA1533.2 15 bp overlap

NR2C1 1 dataset

Motif DE_12h DE_12h-NR2C1_MA1535.2 6 bp overlap

NR2C2 1 dataset

Motif DE_12h DE_12h-NR2C2_MA1536.2 6 bp overlap

Nanog 3 datasets

Motif DE_12h DE_12h-Nanog_MA2339.1 7 bp overlap

Motif DE_48h DE_48h-Nanog_MA2339.1 7 bp overlap

Motif ES_0h ES_0h-Nanog_MA2339.1 7 bp overlap

Nr1H2 1 dataset

Motif DE_12h DE_12h-Nr1H2_MA1996.2 6 bp overlap

Nr1H4 1 dataset

Motif DE_12h DE_12h-Nr1H4_MA1110.3 6 bp overlap

Nr1h3 1 dataset

Motif DE_12h DE_12h-Nr1h3_MA2337.1 6 bp overlap

POLR2A 1 dataset

ChIP GM23338 ENCFF450WCS 491 bp overlap

POU5F1 2 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 461 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 318 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 828 bp overlap

PROX1 1 dataset

Motif DE_24h DE_24h-PROX1_MA0794.1 12 bp overlap

RAD21 5 datasets

ChIP HCT-116 GSE131606.RAD21.HCT-116 264 bp overlap

ChIP T-47D GSE111923.RAD21.T-47D 338 bp overlap

ChIP T-47D_NaCl-isotonic-triptolide GSE111923.RAD21.T-47D_NaCl-isotonic-triptolide 295 bp overlap

ChIP T-47D_triptolide GSE111923.RAD21.T-47D_triptolide 289 bp overlap

ChIP neural ENCSR198ZYJ.RAD21.neural 171 bp overlap

RELA 1 dataset

ChIP LNCaP_DHT_TNFA GSE83860.RELA.LNCaP_DHT_TNFA 160 bp overlap

SMAD2 1 dataset

Motif DE_12h DE_12h-SMAD2_MA1964.2 6 bp overlap

SOX10 1 dataset

Motif DE_24h DE_24h-SOX10_MA0442.3 6 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 338 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 479 bp overlap

SOX2 1 dataset

ChIP hiPSC GSE56567.SOX2.hiPSC 178 bp overlap

SOX4 1 dataset

Motif DE_24h DE_24h-SOX4_MA0867.3 8 bp overlap

SP3 3 datasets

Motif DE_12h DE_12h-SP3_MA0746.3 11 bp overlap

Motif DE_48h DE_48h-SP3_MA0746.3 11 bp overlap

Motif ES_0h ES_0h-SP3_MA0746.3 11 bp overlap

SP8 3 datasets

Motif DE_12h DE_12h-SP8_MA0747.2 11 bp overlap

Motif DE_48h DE_48h-SP8_MA0747.2 11 bp overlap

Motif ES_0h ES_0h-SP8_MA0747.2 11 bp overlap

SP9 3 datasets

Motif DE_12h DE_12h-SP9_MA1564.2 10 bp overlap

Motif DE_48h DE_48h-SP9_MA1564.2 10 bp overlap

Motif ES_0h ES_0h-SP9_MA1564.2 10 bp overlap

SPDEF 1 dataset

Motif DE_48h DE_48h-SPDEF_MA0686.2 10 bp overlap

STAT3 4 datasets

ChIP T-47D_JC4757 GSE126004.STAT3.T-47D_JC4757 377 bp overlap

ChIP T-47D_JC5054 GSE126004.STAT3.T-47D_JC5054 409 bp overlap

ChIP T-47D_JC5056 GSE126004.STAT3.T-47D_JC5056 287 bp overlap

ChIP T-47D_JC5062 GSE126004.STAT3.T-47D_JC5062 169 bp overlap

Sox11 1 dataset

Motif DE_24h DE_24h-Sox11_MA0869.3 8 bp overlap

TAF1 1 dataset

ChIP WA01 ENCSR000BHO.TAF1.WA01 124 bp overlap

TCF4 1 dataset

Motif DE_48h DE_48h-TCF4_MA0830.3 8 bp overlap

TCF7L1 3 datasets

Motif DE_12h DE_12h-TCF7L1_MA1421.1 12 bp overlap

Motif DE_48h DE_48h-TCF7L1_MA1421.1 12 bp overlap

Motif ES_0h ES_0h-TCF7L1_MA1421.1 12 bp overlap

TEAD4 1 dataset

ChIP T-47D_Veh GSE125594.TEAD4.T-47D_Veh 223 bp overlap

YY1 9 datasets

ChIP H1 ENCFF524BTL 337 bp overlap

ChIP HCT-116 ENCSR000BNX.YY1.HCT-116 207 bp overlap

ChIP Hep-G2_NC GSE120104.YY1.Hep-G2_NC 339 bp overlap

ChIP Hep-G2_RBM25-KD GSE120104.YY1.Hep-G2_RBM25-KD 255 bp overlap

ChIP Ishikawa ENCFF505XQX 341 bp overlap

ChIP Ishikawa ENCSR000BSY.YY1.Ishikawa 236 bp overlap

ChIP NT2-D1 ENCSR000EXG.YY1.NT2-D1 126 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 330 bp overlap

ZBTB6 1 dataset

Motif DE_24h DE_24h-ZBTB6_MA1581.2 9 bp overlap

ZEB1 2 datasets

Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap

ChIP neuron_bipolar_doxy_4d ENCSR418KUS.ZEB1.neuron_bipolar_doxy_4d 285 bp overlap

ZFP42 1 dataset

Motif DE_12h DE_12h-ZFP42_MA1651.2 13 bp overlap

ZNF189 1 dataset

Motif DE_12h DE_12h-ZNF189_MA1725.2 9 bp overlap

ZNF341 1 dataset

Motif DE_12h DE_12h-ZNF341_MA1655.2 8 bp overlap

ZNF496 1 dataset

ChIP HEK293T GSE78099.ZNF496.HEK293T 293 bp overlap

ZNF677 1 dataset

Motif DE_12h DE_12h-ZNF677_MA2101.1 12 bp overlap

ZNF708 1 dataset

Motif DE_12h DE_12h-ZNF708_MA1730.2 9 bp overlap

Zbtb2 1 dataset

Motif DE_12h DE_12h-Zbtb2_MA2340.1 10 bp overlap

Zfp335 1 dataset

Motif DE_24h DE_24h-Zfp335_MA2002.2 7 bp overlap