chr13 : 42,592,966 – 42,593,984
1,018 bp 117 TFs 1 linked gene
This 1.0 kb open chromatin element is linked to TNFSF11 and is bound by 117 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
TNFSF11 19.4 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr13:42,587,966 – 42,598,984
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
117 transcription factors
Source
Cell type
AR 1 dataset
ChIP LNCaP_SHGATA2_R1881 GSE69043.AR.LNCaP_SHGATA2_R1881 87 bp overlap
ARID1A 1 dataset
ChIP HAP1 GSE108387.ARID1A.HAP1 514 bp overlap
ASCL1 1 dataset
ChIP NCI-H889 GSE69394.ASCL1.NCI-H889 143 bp overlap
ASH2L 3 datasets
ChIP H1 ENCFF399KAM 738 bp overlap
ChIP H1 ENCFF399KAM 785 bp overlap
ChIP WA01 ENCSR850KIP.ASH2L.WA01 650 bp overlap
ATF2 1 dataset
ChIP WA01 ENCSR000BQU.ATF2.WA01 732 bp overlap
ATF4 1 dataset
Motif ES_0h ES_0h-ATF4_MA0833.3 10 bp overlap
BCL11A 3 datasets
ChIP H1 ENCFF833IPY 145 bp overlap
ChIP WA01 ENCSR000BMJ.BCL11A.WA01 146 bp overlap
ChIP WA01 ENCSR000BIP.BCL11A.WA01 108 bp overlap
BCOR 1 dataset
ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 380 bp overlap
BRD4 6 datasets
ChIP Mutu-1_vehicle GSE84213.BRD4.Mutu-1_vehicle 241 bp overlap
ChIP Mutu-1_vehicle GSE84213.BRD4.Mutu-1_vehicle 472 bp overlap
ChIP NMC24335 GSE96775.BRD4.NMC24335 276 bp overlap
ChIP cortical-interneuron_R133C_KCl-neg_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-neg_JQ1-neg 485 bp overlap
ChIP cortical-interneuron_R133C_KCl-neg_JQ1-pos GSE117508.BRD4.cortical-interneuron_R133C_KCl-neg_JQ1-pos 232 bp overlap
ChIP cortical-interneuron_R133C_KCl-pos_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-pos_JQ1-neg 183 bp overlap
CEBPG 1 dataset
Motif ES_0h ES_0h-CEBPG_MA1636.2 10 bp overlap
CHD1 2 datasets
ChIP WA01 ENCSR000AQK.CHD1.WA01 271 bp overlap
ChIP WA01 ENCSR000AQK.CHD1.WA01 161 bp overlap
CREB1 2 datasets
ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 167 bp overlap
ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 189 bp overlap
CTBP2 1 dataset
ChIP WA01 ENCSR000EUO.CTBP2.WA01 505 bp overlap
CTCF 3 datasets
ChIP CD14 ENCSR000ATN.CTCF.CD14 428 bp overlap
ChIP HAP1_clone21_CTCF-CRISPR GSE152721.CTCF.HAP1_clone21_CTCF-CRISPR 247 bp overlap
ChIP keratinocyte GSE154221.CTCF.keratinocyte 350 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF335XTP 218 bp overlap
E2F6 1 dataset
Motif ES_0h ES_0h-E2F6_MA0471.3 8 bp overlap
EHF 1 dataset
Motif ES_0h ES_0h-EHF_MA0598.4 9 bp overlap
ELF1 1 dataset
Motif ES_0h ES_0h-ELF1_MA0473.4 9 bp overlap
ELF3 1 dataset
Motif ES_0h ES_0h-ELF3_MA0640.3 9 bp overlap
EP300 3 datasets
ChIP H1 ENCFF927IYK 297 bp overlap
ChIP WA01 ENCSR000BKK.EP300.WA01 425 bp overlap
ChIP hESC GSE17917.EP300.hESC 501 bp overlap
ERF::FOXI1 1 dataset
Motif ES_0h ES_0h-ERFFOXI1_MA1935.2 10 bp overlap
ERF::FOXO1 1 dataset
Motif ES_0h ES_0h-ERFFOXO1_MA1936.2 12 bp overlap
ERF::HOXB13 1 dataset
Motif ES_0h ES_0h-ERFHOXB13_MA1937.2 13 bp overlap
ETV1 1 dataset
Motif ES_0h ES_0h-ETV1_MA0761.3 9 bp overlap
ETV2::DRGX 1 dataset
Motif ES_0h ES_0h-ETV2DRGX_MA1940.2 12 bp overlap
ETV2::FOXI1 1 dataset
Motif ES_0h ES_0h-ETV2FOXI1_MA1942.2 11 bp overlap
ETV5::DRGX 1 dataset
Motif ES_0h ES_0h-ETV5DRGX_MA1944.2 12 bp overlap
ETV5::FOXI1 1 dataset
Motif ES_0h ES_0h-ETV5FOXI1_MA1946.2 12 bp overlap
ETV5::HOXA2 1 dataset
Motif ES_0h ES_0h-ETV5HOXA2_MA1948.2 12 bp overlap
EWSR1-FLI1 1 dataset
Motif ES_0h ES_0h-EWSR1-FLI1_MA0149.1 18 bp overlap
Elf5 1 dataset
Motif ES_0h ES_0h-Elf5_MA0136.4 8 bp overlap
Erg 1 dataset
Motif ES_0h ES_0h-Erg_MA0474.4 10 bp overlap
FLI1::DRGX 1 dataset
Motif ES_0h ES_0h-FLI1DRGX_MA1949.2 14 bp overlap
FLI1::FOXI1 1 dataset
Motif ES_0h ES_0h-FLI1FOXI1_MA1950.2 11 bp overlap
FOS::JUN 1 dataset
Motif ES_0h ES_0h-FOSJUN_MA1126.2 10 bp overlap
FOXJ2::ELF1 1 dataset
Motif ES_0h ES_0h-FOXJ2ELF1_MA1952.2 11 bp overlap
FOXO1::ELF1 1 dataset
Motif ES_0h ES_0h-FOXO1ELF1_MA1953.2 13 bp overlap
FOXO1::ELK1 1 dataset
Motif ES_0h ES_0h-FOXO1ELK1_MA1954.2 13 bp overlap
FOXO1::ELK3 1 dataset
Motif ES_0h ES_0h-FOXO1ELK3_MA1955.2 13 bp overlap
FOXP1 1 dataset
ChIP H9 GSE31006.FOXP1.H9 268 bp overlap
GABPA 1 dataset
Motif ES_0h ES_0h-GABPA_MA0062.4 10 bp overlap
GATA2 1 dataset
ChIP LNCaP_CSFCS GSE69043.GATA2.LNCaP_CSFCS 105 bp overlap
GATA3 4 datasets
ChIP MCF-7 ENCSR000EWS.GATA3.MCF-7 178 bp overlap
ChIP MCF-7 GSE51274.GATA3.MCF-7 131 bp overlap
ChIP MCF-7_E2 GSE29073.GATA3.MCF-7_E2 69 bp overlap
ChIP MCF-7_sgScr GSE133072.GATA3.MCF-7_sgScr 147 bp overlap
GATA3_Nter 2 datasets
ChIP T-47D_CR3flp GSE99479.GATA3_Nter.T-47D_CR3flp 124 bp overlap
ChIP T-47D_flp-ctrl GSE99479.GATA3_Nter.T-47D_flp-ctrl 138 bp overlap
GTF3C2 1 dataset
ChIP T98G GSE120162.GTF3C2.T98G 80 bp overlap
HDAC2 7 datasets
ChIP H1 ENCFF353UJQ 645 bp overlap
ChIP H1 ENCFF353UJQ 250 bp overlap
ChIP H1 ENCFF939VKA 237 bp overlap
ChIP H1 ENCFF939VKA 237 bp overlap
ChIP WA01 ENCSR000BNR.HDAC2.WA01 568 bp overlap
ChIP WA01 ENCSR000AVB.HDAC2.WA01 852 bp overlap
ChIP WA01 ENCSR000BNR.HDAC2.WA01 171 bp overlap
HOXA4 1 dataset
Motif ES_0h ES_0h-HOXA4_MA1496.2 7 bp overlap
HOXB2::ELK1 1 dataset
Motif ES_0h ES_0h-HOXB2ELK1_MA1957.1 14 bp overlap
HOXB4 2 datasets
Motif ES_0h ES_0h-HOXB4_MA1499.2 6 bp overlap
Motif ES_0h ES_0h-HOXB4_MA1499.2 6 bp overlap
HOXC4 2 datasets
Motif ES_0h ES_0h-HOXC4_MA1504.2 6 bp overlap
Motif ES_0h ES_0h-HOXC4_MA1504.2 6 bp overlap
HOXD3 1 dataset
Motif ES_0h ES_0h-HOXD3_MA0912.2 8 bp overlap
HOXD4 2 datasets
Motif ES_0h ES_0h-HOXD4_MA1507.2 6 bp overlap
Motif ES_0h ES_0h-HOXD4_MA1507.2 6 bp overlap
IKZF1 1 dataset
Motif ES_0h ES_0h-IKZF1_MA1508.2 8 bp overlap
IKZF2 3 datasets
Motif ES_0h ES_0h-IKZF2_MA2326.1 6 bp overlap
Motif ES_0h ES_0h-IKZF2_MA2326.1 6 bp overlap
Motif ES_0h ES_0h-IKZF2_MA2326.1 6 bp overlap
Ikzf3 1 dataset
Motif ES_0h ES_0h-Ikzf3_MA1992.2 9 bp overlap
JUN 3 datasets
ChIP ESC S24-ESC-d0-JUN-exp1 559 bp overlap
ChIP ESC S34-ESC-d0-JUN-exp2 478 bp overlap
ChIP HUES-8 GSE109524.JUN.HUES-8 710 bp overlap
KDM1A 2 datasets
ChIP H1 ENCFF696SGD 505 bp overlap
ChIP H1 ENCFF696SGD 505 bp overlap
MAX 4 datasets
ChIP NCI-H2171 GSE41105.MAX.NCI-H2171 178 bp overlap
ChIP NCI-H2171 GSE36354.MAX.NCI-H2171 139 bp overlap
ChIP WA01 ENCSR000EUP.MAX.WA01 188 bp overlap
ChIP WTC11 ENCFF223QFY 585 bp overlap
MITF 4 datasets
ChIP 501-mel GSE137522.MITF.501-mel 368 bp overlap
ChIP 501-mel GSE61965.MITF.501-mel 182 bp overlap
ChIP 501-mel_20ng_K243R GSE137522.MITF.501-mel_20ng_K243R 296 bp overlap
ChIP 501-mel_K243Q GSE137522.MITF.501-mel_K243Q 281 bp overlap
MORC2 1 dataset
ChIP H9 GSE95374.MORC2.H9 395 bp overlap
MYC 1 dataset
ChIP NCI-H2171 GSE36354.MYC.NCI-H2171 311 bp overlap
NANOG 12 datasets
ChIP GM23338 ENCFF065NZG 311 bp overlap
ChIP GM23338 ENCSR061DGF.NANOG.GM23338 526 bp overlap
ChIP HUES-8 GSE109524.NANOG.HUES-8 940 bp overlap
ChIP WA01 ERP004238.NANOG.WA01 938 bp overlap
ChIP WA01 ENCSR000BMT.NANOG.WA01 266 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 229 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 612 bp overlap
ChIP WA09 GSE105028.NANOG.WA09 315 bp overlap
ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 284 bp overlap
ChIP hESC GSE18292.NANOG.hESC 98 bp overlap
ChIP hESC GSE20650.NANOG.hESC 412 bp overlap
ChIP hESC GSE18292.NANOG.hESC 276 bp overlap
NEUROD1 2 datasets
ChIP D341-Med_shGFP GSE92582.NEUROD1.D341-Med_shGFP 235 bp overlap
ChIP NCI-H524 GSE69394.NEUROD1.NCI-H524 118 bp overlap
NIPBL 3 datasets
ChIP hESC GSE64758.NIPBL.hESC 359 bp overlap
ChIP hESC_WNT3A GSE64758.NIPBL.hESC_WNT3A 240 bp overlap
ChIP hESC_activin GSE64758.NIPBL.hESC_activin 261 bp overlap
PAX5 1 dataset
ChIP GM12878 ENCFF482PUW 89 bp overlap
POLR2A 4 datasets
ChIP GM12891 ENCFF012SUT 565 bp overlap
ChIP GM12891 ENCFF012SUT 565 bp overlap
ChIP GM12892 ENCFF542ZFO 545 bp overlap
ChIP GM23338 ENCFF450WCS 454 bp overlap
POU1F1 1 dataset
Motif ES_0h ES_0h-POU1F1_MA0784.3 14 bp overlap
POU2F1 1 dataset
Motif ES_0h ES_0h-POU2F1_MA0785.2 9 bp overlap
POU2F2 1 dataset
Motif ES_0h ES_0h-POU2F2_MA0507.3 13 bp overlap
POU2F3 1 dataset
Motif ES_0h ES_0h-POU2F3_MA0627.3 9 bp overlap
POU3F1 1 dataset
Motif ES_0h ES_0h-POU3F1_MA0786.2 10 bp overlap
POU3F2 1 dataset
Motif ES_0h ES_0h-POU3F2_MA0787.1 12 bp overlap
POU3F3 1 dataset
Motif ES_0h ES_0h-POU3F3_MA0788.1 13 bp overlap
POU3F4 1 dataset
Motif ES_0h ES_0h-POU3F4_MA0789.1 9 bp overlap
POU5F1 13 datasets
ChIP GM23338 ENCFF333SNB 311 bp overlap
ChIP GM23338 ENCFF333SNB 311 bp overlap
ChIP HUES-8 GSE109524.POU5F1.HUES-8 1018 bp overlap
ChIP NCCIT GSE36134.POU5F1.NCCIT 305 bp overlap
ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 844 bp overlap
ChIP OSKM GSE81899.POU5F1.OSKM 242 bp overlap
ChIP WA09 GSE105028.POU5F1.WA09 190 bp overlap
ChIP WA09_heat-shock GSE105028.POU5F1.WA09_heat-shock 228 bp overlap
ChIP hESC ENCSR264RJX.POU5F1.hESC 882 bp overlap
ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 380 bp overlap
ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 910 bp overlap
ChIP hiPSC GSE56567.POU5F1.hiPSC 210 bp overlap
ChIP hiPSC_3s2 GSE81899.POU5F1.hiPSC_3s2 500 bp overlap
POU5F1B 1 dataset
Motif ES_0h ES_0h-POU5F1B_MA0792.1 9 bp overlap
POU6F1 2 datasets
Motif ES_0h ES_0h-POU6F1_MA1549.2 7 bp overlap
Motif ES_0h ES_0h-POU6F1_MA1549.2 7 bp overlap
POU6F2 1 dataset
Motif ES_0h ES_0h-POU6F2_MA0793.2 9 bp overlap
PPARG 1 dataset
Motif ES_0h ES_0h-PPARG_MA0066.2 19 bp overlap
PRDM9 2 datasets
Motif ES_0h ES_0h-PRDM9_MA1723.2 20 bp overlap
Motif ES_0h ES_0h-PRDM9_MA1723.2 20 bp overlap
RAD21 3 datasets
ChIP HAP1 GSE152721.RAD21.HAP1 382 bp overlap
ChIP HAP1_CTCF GSE126634.RAD21.HAP1_CTCF 534 bp overlap
ChIP HAP1_clone25 GSE152721.RAD21.HAP1_clone25 300 bp overlap
SALL3 2 datasets
ChIP hiPSC GSE104863.SALL3.hiPSC 204 bp overlap
ChIP hiPSC GSE104863.SALL3.hiPSC 298 bp overlap
SIN3A 4 datasets
ChIP H1 ENCFF042ZSL 464 bp overlap
ChIP WA01 ENCSR000EBO.SIN3A.WA01 321 bp overlap
ChIP WA01 ENCSR000BIS.SIN3A.WA01 216 bp overlap
ChIP hiPSC_IID12 GSE106870.SIN3A.hiPSC_IID12 162 bp overlap
SMAD1 1 dataset
ChIP BG03 GSE36578.SMAD1.BG03 104 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8 GSE109524.SMAD2-3.HUES-8 421 bp overlap
SMAD2_3 1 dataset
ChIP ESC S33-ESC-d0-SMAD2_3-exp2 472 bp overlap
SMAD3 4 datasets
ChIP BG03 GSE21614.SMAD3.BG03 498 bp overlap
ChIP BG03_DIFF_0H GSE36578.SMAD3.BG03_DIFF_0H 471 bp overlap
ChIP BG03_DIFF_2H GSE36578.SMAD3.BG03_DIFF_2H 388 bp overlap
ChIP hESC GSE75297.SMAD3.hESC 327 bp overlap
SMARCA4 2 datasets
ChIP hiPSC GSE124903.SMARCA4.hiPSC 674 bp overlap
ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 976 bp overlap
SMARCB1 2 datasets
ChIP hiPSC GSE124903.SMARCB1.hiPSC 336 bp overlap
ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 917 bp overlap
SMARCC1 4 datasets
ChIP ESC S25-ESC-d0-BAF155-exp1 466 bp overlap
ChIP ESC S25-ESC-d0-BAF155-exp1 427 bp overlap
ChIP hiPSC GSE124903.SMARCC1.hiPSC 211 bp overlap
ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 878 bp overlap
SMC1 1 dataset
ChIP HAP1_WaplKO-33 GSE94992.SMC1.HAP1_WaplKO-33 208 bp overlap
SOX2 8 datasets
ChIP H9 GSE46837.SOX2.H9 327 bp overlap
ChIP OSKM GSE81899.SOX2.OSKM 327 bp overlap
ChIP hESC GSE18292.SOX2.hESC 131 bp overlap
ChIP hESC GSE69479.SOX2.hESC 337 bp overlap
ChIP hESC GSE18292.SOX2.hESC 174 bp overlap
ChIP hiPSC GSE56567.SOX2.hiPSC 188 bp overlap
ChIP hiPSC GSE56567.SOX2.hiPSC 397 bp overlap
ChIP hiPSC_3s2 GSE81899.SOX2.hiPSC_3s2 307 bp overlap
SP1 1 dataset
ChIP WA01 ENCSR000BIR.SP1.WA01 195 bp overlap
SP4 1 dataset
ChIP H1 ENCFF473YOB 597 bp overlap
SPIB 1 dataset
Motif ES_0h ES_0h-SPIB_MA0081.3 13 bp overlap
SPIC 1 dataset
Motif ES_0h ES_0h-SPIC_MA0687.2 13 bp overlap
SREBF1 1 dataset
Motif ES_0h ES_0h-SREBF1_MA0595.1 10 bp overlap
SREBF2 1 dataset
Motif ES_0h ES_0h-SREBF2_MA0596.1 10 bp overlap
Spi1 1 dataset
Motif ES_0h ES_0h-Spi1_MA0080.7 13 bp overlap
TBP 2 datasets
ChIP hESC GSE122298.TBP.hESC 122 bp overlap
ChIP hESC_2h GSE122298.TBP.hESC_2h 174 bp overlap
TCF12 2 datasets
ChIP H1 ENCFF203EBH 251 bp overlap
ChIP WA01 ENCSR000BIT.TCF12.WA01 366 bp overlap
TCF3 1 dataset
ChIP NPC GSE154479.TCF3.NPC 885 bp overlap
TCF4 1 dataset
ChIP GEN2-2 GSE76147.TCF4.GEN2-2 149 bp overlap
TEAD1 1 dataset
ChIP WTC11 ENCFF502QUV 405 bp overlap
TEAD4 3 datasets
ChIP ESC S26-ESC-d0-TEAD4-exp1 633 bp overlap
ChIP H1 ENCFF778PAX 245 bp overlap
ChIP hESC GSE99202.TEAD4.hESC 652 bp overlap
THAP1 1 dataset
Motif ES_0h ES_0h-THAP1_MA0597.3 8 bp overlap
USF1 4 datasets
ChIP H1 ENCFF090WVU 188 bp overlap
ChIP SK-N-SH ENCSR000BMF.USF1.SK-N-SH 142 bp overlap
ChIP WA01 ENCSR000BIU.USF1.WA01 299 bp overlap
ChIP WTC11 ENCFF699QGS 303 bp overlap
USF2 3 datasets
ChIP H1 ENCFF434EDF 237 bp overlap
ChIP WA01 ENCSR000ECD.USF2.WA01 129 bp overlap
ChIP WTC11 ENCFF139JAW 168 bp overlap
YY1 1 dataset
ChIP WA01 ENCSR000BKD.YY1.WA01 214 bp overlap
ZFP14 1 dataset
Motif ES_0h ES_0h-ZFP14_MA1972.1 15 bp overlap
ZNF175 1 dataset
Motif ES_0h ES_0h-ZNF175_MA2332.1 9 bp overlap
ZNF207 1 dataset
ChIP WA09 GSE118632.ZNF207.WA09 663 bp overlap
ZNF354C 1 dataset
Motif ES_0h ES_0h-ZNF354C_MA0130.1 6 bp overlap
ZNF462 1 dataset
ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 985 bp overlap
ZNF558 1 dataset
Motif ES_0h ES_0h-ZNF558_MA2335.1 29 bp overlap
ZNF573 1 dataset
ChIP HEK293T GSE78099.ZNF573.HEK293T 175 bp overlap
ZNF675 1 dataset
Motif ES_0h ES_0h-ZNF675_MA1714.2 19 bp overlap
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