chr12 : 21,604,321 – 21,604,946
625 bp 124 TFs 1 linked gene
This 625 bp open chromatin element is linked to GYS2 and is bound by 124 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
GYS2 at TSS At TSS Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr12:21,599,321 – 21,609,946
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
124 transcription factors
Source
Cell type
AR 1 dataset
ChIP LNCaP_DHTTHZ1 GSE125245.AR.LNCaP_DHTTHZ1 130 bp overlap
ARGFX 1 dataset
Motif DE_12h DE_12h-ARGFX_MA1463.2 8 bp overlap
ATF3 2 datasets
ChIP liver ENCSR480LIS.ATF3.liver 172 bp overlap
ChIP liver ENCSR205FOW.ATF3.liver 154 bp overlap
Alx4 1 dataset
Motif DE_12h DE_12h-Alx4_MA0853.2 12 bp overlap
Arx 1 dataset
Motif DE_12h DE_12h-Arx_MA0874.2 10 bp overlap
BARX1 1 dataset
Motif DE_12h DE_12h-BARX1_MA0875.2 6 bp overlap
BSX 1 dataset
Motif DE_12h DE_12h-BSX_MA0876.2 6 bp overlap
CDX2 1 dataset
Motif DE_12h DE_12h-CDX2_MA0465.3 8 bp overlap
CEBPA 1 dataset
ChIP liver ERP002306.CEBPA.liver 111 bp overlap
Crx 1 dataset
Motif DE_12h DE_12h-Crx_MA0467.3 6 bp overlap
DLX1 1 dataset
Motif DE_12h DE_12h-DLX1_MA0879.3 6 bp overlap
DLX6 1 dataset
Motif DE_12h DE_12h-DLX6_MA0882.2 6 bp overlap
DMRTA2 1 dataset
Motif DE_12h DE_12h-DMRTA2_MA1478.2 6 bp overlap
DMRTC2 1 dataset
Motif DE_12h DE_12h-DMRTC2_MA1479.2 11 bp overlap
Dlx2 1 dataset
Motif DE_12h DE_12h-Dlx2_MA0885.3 8 bp overlap
Dlx3 1 dataset
Motif DE_12h DE_12h-Dlx3_MA0880.2 6 bp overlap
Dlx4 1 dataset
Motif DE_12h DE_12h-Dlx4_MA0881.2 6 bp overlap
Dlx5 1 dataset
Motif DE_12h DE_12h-Dlx5_MA1476.3 8 bp overlap
EGR1 3 datasets
ChIP liver ENCFF130MBW 201 bp overlap
ChIP liver ENCSR736BUG.EGR1.liver 113 bp overlap
ChIP liver ENCSR290ZOS.EGR1.liver 110 bp overlap
EGR4 1 dataset
Motif DE_12h DE_12h-EGR4_MA0733.2 11 bp overlap
EHF 1 dataset
Motif DE_12h DE_12h-EHF_MA0598.4 9 bp overlap
ELF1 1 dataset
Motif DE_12h DE_12h-ELF1_MA0473.4 9 bp overlap
ELF2 1 dataset
Motif DE_12h DE_12h-ELF2_MA1483.3 10 bp overlap
ELF3 1 dataset
Motif DE_12h DE_12h-ELF3_MA0640.3 9 bp overlap
ELK1 1 dataset
Motif DE_12h DE_12h-ELK1_MA0028.3 9 bp overlap
ERF 1 dataset
Motif DE_12h DE_12h-ERF_MA0760.2 9 bp overlap
ERF::FOXI1 2 datasets
Motif DE_12h DE_12h-ERFFOXI1_MA1935.2 10 bp overlap
Motif DE_12h DE_12h-ERFFOXI1_MA1935.2 10 bp overlap
ETS1 1 dataset
Motif DE_12h DE_12h-ETS1_MA0098.4 9 bp overlap
ETS2 1 dataset
Motif DE_12h DE_12h-ETS2_MA1484.2 9 bp overlap
ETV1 2 datasets
Motif DE_12h DE_12h-ETV1_MA0761.3 9 bp overlap
Motif DE_12h DE_12h-ETV1_MA0761.3 9 bp overlap
ETV2 1 dataset
Motif DE_12h DE_12h-ETV2_MA0762.2 9 bp overlap
ETV2::FOXI1 2 datasets
Motif DE_12h DE_12h-ETV2FOXI1_MA1942.2 11 bp overlap
Motif DE_12h DE_12h-ETV2FOXI1_MA1942.2 11 bp overlap
ETV3 1 dataset
Motif DE_12h DE_12h-ETV3_MA0763.2 9 bp overlap
ETV4 1 dataset
Motif DE_12h DE_12h-ETV4_MA0764.4 9 bp overlap
ETV5::FOXI1 1 dataset
Motif DE_12h DE_12h-ETV5FOXI1_MA1946.2 12 bp overlap
ETV5::FOXO1 1 dataset
Motif DE_12h DE_12h-ETV5FOXO1_MA1947.2 10 bp overlap
EZH2 1 dataset
ChIP LNCaP GSE39459.EZH2.LNCaP 191 bp overlap
Elf5 1 dataset
Motif DE_12h DE_12h-Elf5_MA0136.4 8 bp overlap
Erg 1 dataset
Motif DE_12h DE_12h-Erg_MA0474.4 10 bp overlap
FEV 1 dataset
Motif DE_12h DE_12h-FEV_MA0156.4 9 bp overlap
FLI1 1 dataset
Motif DE_12h DE_12h-FLI1_MA0475.3 9 bp overlap
FLI1::DRGX 1 dataset
Motif DE_12h DE_12h-FLI1DRGX_MA1949.2 14 bp overlap
FLI1::FOXI1 2 datasets
Motif DE_12h DE_12h-FLI1FOXI1_MA1950.2 11 bp overlap
Motif DE_12h DE_12h-FLI1FOXI1_MA1950.2 11 bp overlap
FOXA1 4 datasets
ChIP liver ENCFF749ERP 177 bp overlap
ChIP liver ERP002306.FOXA1.liver 182 bp overlap
ChIP liver ENCSR735KEY.FOXA1.liver 124 bp overlap
ChIP liver ENCSR324RCI.FOXA1.liver 116 bp overlap
FOXA2 5 datasets
ChIP Caco-2 GSE66218.FOXA2.Caco-2 138 bp overlap
ChIP DE DE-FOXA2-1 293 bp overlap
ChIP liver ENCFF888VJF 132 bp overlap
ChIP liver ENCSR310NYI.FOXA2.liver 155 bp overlap
ChIP liver ENCSR080XEY.FOXA2.liver 155 bp overlap
FOXJ2::ELF1 2 datasets
Motif DE_12h DE_12h-FOXJ2ELF1_MA1952.2 11 bp overlap
Motif DE_12h DE_12h-FOXJ2ELF1_MA1952.2 11 bp overlap
FOXO1::ELF1 1 dataset
Motif DE_12h DE_12h-FOXO1ELF1_MA1953.2 13 bp overlap
FOXO1::ELK1 2 datasets
Motif DE_12h DE_12h-FOXO1ELK1_MA1954.2 13 bp overlap
Motif DE_12h DE_12h-FOXO1ELK1_MA1954.2 13 bp overlap
FOXO1::ELK3 2 datasets
Motif DE_12h DE_12h-FOXO1ELK3_MA1955.2 13 bp overlap
Motif DE_12h DE_12h-FOXO1ELK3_MA1955.2 13 bp overlap
FOXO1::FLI1 1 dataset
Motif DE_12h DE_12h-FOXO1FLI1_MA1956.2 13 bp overlap
GABPA 3 datasets
Motif DE_12h DE_12h-GABPA_MA0062.4 10 bp overlap
ChIP liver ENCFF500III 250 bp overlap
ChIP liver ENCSR038GMB.GABPA.liver 159 bp overlap
GATA2 1 dataset
ChIP LNCaP_CSFCS GSE69043.GATA2.LNCaP_CSFCS 130 bp overlap
GATA4 3 datasets
ChIP DE DE-GATA4-1 504 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 625 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 213 bp overlap
GATA6 5 datasets
ChIP DE_D1 S09-DE-d1-GATA6-exp1 616 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 263 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 370 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 363 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 625 bp overlap
GBX2 1 dataset
Motif DE_12h DE_12h-GBX2_MA0890.2 6 bp overlap
GSC 1 dataset
Motif DE_12h DE_12h-GSC_MA0648.2 6 bp overlap
GSC2 1 dataset
Motif DE_12h DE_12h-GSC2_MA0891.2 6 bp overlap
Gli1 1 dataset
Motif DE_12h DE_12h-Gli1_MA1990.2 10 bp overlap
Gli2 1 dataset
Motif DE_12h DE_12h-Gli2_MA0734.4 9 bp overlap
HESX1 1 dataset
Motif DE_12h DE_12h-HESX1_MA0894.2 6 bp overlap
HNF4A 4 datasets
ChIP Caco-2_DIFF GSE23436.HNF4A.Caco-2_DIFF 54 bp overlap
ChIP liver ENCFF354NRH 187 bp overlap
ChIP liver ENCFF449HPV 229 bp overlap
ChIP liver ERP002306.HNF4A.liver 190 bp overlap
HNF4G 2 datasets
ChIP liver ENCFF170YNZ 176 bp overlap
ChIP liver ENCSR297GII.HNF4G.liver 130 bp overlap
HOXA7 1 dataset
Motif DE_12h DE_12h-HOXA7_MA1498.3 6 bp overlap
HOXB13 1 dataset
Motif DE_12h DE_12h-HOXB13_MA0901.3 9 bp overlap
Hnf1A 2 datasets
Motif DE_12h DE_12h-Hnf1A_MA1991.2 10 bp overlap
Motif DE_12h DE_12h-Hnf1A_MA1991.2 10 bp overlap
Hoxa13 1 dataset
Motif DE_12h DE_12h-Hoxa13_MA0650.4 8 bp overlap
Hoxd13 1 dataset
Motif DE_12h DE_12h-Hoxd13_MA0909.4 7 bp overlap
IKZF1 3 datasets
Motif DE_12h DE_12h-IKZF1_MA1508.2 8 bp overlap
Motif DE_12h DE_12h-IKZF1_MA1508.2 8 bp overlap
ChIP K-562 ENCSR395HWC.IKZF1.K-562 245 bp overlap
IKZF2 1 dataset
Motif DE_12h DE_12h-IKZF2_MA2326.1 6 bp overlap
Ikzf3 1 dataset
Motif DE_12h DE_12h-Ikzf3_MA1992.2 9 bp overlap
Irf1 1 dataset
Motif DE_12h DE_12h-Irf1_MA0050.4 11 bp overlap
JUND 4 datasets
ChIP liver ENCFF007WWT 224 bp overlap
ChIP liver ENCFF557PGE 192 bp overlap
ChIP liver ENCSR837GTK.JUND.liver 185 bp overlap
ChIP liver ENCSR196HGZ.JUND.liver 172 bp overlap
KLF4 1 dataset
ChIP BJ_INDUCED GSE36570.KLF4.BJ_INDUCED 50 bp overlap
LBX2 1 dataset
Motif DE_12h DE_12h-LBX2_MA0699.2 6 bp overlap
LHX2 1 dataset
Motif DE_12h DE_12h-LHX2_MA0700.3 6 bp overlap
LIN54 1 dataset
Motif DE_12h DE_12h-LIN54_MA0619.2 7 bp overlap
Lef1 1 dataset
Motif DE_12h DE_12h-Lef1_MA0768.3 8 bp overlap
MAX 4 datasets
ChIP liver ENCFF092GVW 298 bp overlap
ChIP liver ENCFF584QGB 190 bp overlap
ChIP liver ENCSR521IID.MAX.liver 164 bp overlap
ChIP liver ENCSR847DIT.MAX.liver 135 bp overlap
MED1 1 dataset
ChIP SGBS_TNF GSE64233.MED1.SGBS_TNF 213 bp overlap
MEIS1 1 dataset
Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap
MSX1 1 dataset
Motif DE_12h DE_12h-MSX1_MA0666.3 6 bp overlap
MSX2 1 dataset
Motif DE_12h DE_12h-MSX2_MA0708.3 6 bp overlap
Msx3 1 dataset
Motif DE_12h DE_12h-Msx3_MA0709.2 6 bp overlap
NANOG 1 dataset
ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 219 bp overlap
NR2F2 4 datasets
ChIP liver ENCFF427MRU 124 bp overlap
ChIP liver ENCFF565JGD 221 bp overlap
ChIP liver ENCSR338MMB.NR2F2.liver 142 bp overlap
ChIP liver ENCSR168SMX.NR2F2.liver 121 bp overlap
Nfe2l2 1 dataset
Motif DE_12h DE_12h-Nfe2l2_MA0150.3 11 bp overlap
Nobox 1 dataset
Motif DE_12h DE_12h-Nobox_MA0125.2 6 bp overlap
OTX1 1 dataset
Motif DE_12h DE_12h-OTX1_MA0711.2 6 bp overlap
OTX2 1 dataset
Motif DE_12h DE_12h-OTX2_MA0712.3 7 bp overlap
PITX1 1 dataset
Motif DE_12h DE_12h-PITX1_MA0682.3 6 bp overlap
PITX3 1 dataset
Motif DE_12h DE_12h-PITX3_MA0714.2 6 bp overlap
POLR2A 1 dataset
ChIP right lobe of liver ENCFF026NCK 301 bp overlap
Prdm4 1 dataset
Motif DE_12h DE_12h-Prdm4_MA1647.3 11 bp overlap
RAD21 2 datasets
ChIP liver ENCFF485PAC 241 bp overlap
ChIP liver ENCFF522JHE 147 bp overlap
RAX 1 dataset
Motif DE_12h DE_12h-RAX_MA0718.2 6 bp overlap
RBPJ 2 datasets
Motif DE_12h DE_12h-RBPJ_MA1116.2 6 bp overlap
Motif DE_12h DE_12h-RBPJ_MA1116.2 6 bp overlap
RELA 2 datasets
Motif DE_12h DE_12h-RELA_MA0107.1 10 bp overlap
ChIP SGBS_TNF GSE64233.RELA.SGBS_TNF 195 bp overlap
REST 4 datasets
ChIP liver ENCFF240FWT 312 bp overlap
ChIP liver ENCFF577AZT 341 bp overlap
ChIP liver ENCSR867WPH.REST.liver 305 bp overlap
ChIP liver ENCSR893QWP.REST.liver 230 bp overlap
RFX4 1 dataset
Motif DE_12h DE_12h-RFX4_MA0799.3 13 bp overlap
RHOXF1 1 dataset
Motif DE_12h DE_12h-RHOXF1_MA0719.2 6 bp overlap
RXRA 2 datasets
ChIP liver ENCFF077DAP 219 bp overlap
ChIP liver ENCFF807CIA 222 bp overlap
Rfx6 1 dataset
Motif DE_12h DE_12h-Rfx6_MA1724.2 9 bp overlap
SMAD4 1 dataset
ChIP Caco-2 GSE112946.SMAD4.Caco-2 125 bp overlap
SP1 2 datasets
ChIP liver ENCFF597LFJ 192 bp overlap
ChIP liver ENCFF769YSM 164 bp overlap
Stat2 1 dataset
Motif DE_12h DE_12h-Stat2_MA1623.2 10 bp overlap
TAF1 2 datasets
ChIP liver ENCFF610UQP 189 bp overlap
ChIP liver ENCSR016BMM.TAF1.liver 605 bp overlap
TCF7L1 1 dataset
Motif DE_12h DE_12h-TCF7L1_MA1421.1 12 bp overlap
TCF7L2 1 dataset
Motif DE_12h DE_12h-TCF7L2_MA0523.2 9 bp overlap
TEAD1 1 dataset
Motif DE_12h DE_12h-TEAD1_MA0090.4 9 bp overlap
TEAD2 1 dataset
Motif DE_12h DE_12h-TEAD2_MA1121.2 7 bp overlap
TEAD3 1 dataset
Motif DE_12h DE_12h-TEAD3_MA0808.1 8 bp overlap
TEAD4 1 dataset
Motif DE_12h DE_12h-TEAD4_MA0809.3 8 bp overlap
Wt1 1 dataset
Motif DE_12h DE_12h-Wt1_MA1627.2 10 bp overlap
YY1 3 datasets
ChIP liver ENCFF400MBC 133 bp overlap
ChIP liver ENCFF515BWJ 325 bp overlap
ChIP liver ENCSR994YLZ.YY1.liver 164 bp overlap
ZBTB33 2 datasets
ChIP liver ENCFF592BJA 216 bp overlap
ChIP liver ENCSR516HUP.ZBTB33.liver 175 bp overlap
ZKSCAN5 1 dataset
Motif DE_12h DE_12h-ZKSCAN5_MA1652.2 9 bp overlap
ZNF157 1 dataset
Motif DE_12h DE_12h-ZNF157_MA2331.1 21 bp overlap
ZNF175 2 datasets
Motif DE_12h DE_12h-ZNF175_MA2332.1 9 bp overlap
Motif DE_12h DE_12h-ZNF175_MA2332.1 9 bp overlap
ZNF354C 1 dataset
Motif DE_12h DE_12h-ZNF354C_MA0130.1 6 bp overlap
ZNF449 1 dataset
Motif DE_12h DE_12h-ZNF449_MA1656.2 10 bp overlap
ZNF496 1 dataset
ChIP HEK293T GSE78099.ZNF496.HEK293T 294 bp overlap
ZNF680 1 dataset
Motif DE_12h DE_12h-ZNF680_MA1729.2 11 bp overlap
ZNF768 1 dataset
Motif DE_12h DE_12h-ZNF768_MA1731.2 9 bp overlap
ZNF85 1 dataset
Motif DE_12h DE_12h-ZNF85_MA1720.2 12 bp overlap
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