chr1:15,676,618–15,677,408

chr1 : 15,676,618 – 15,677,408

790 bp 95 TFs 10 linked genes

This 790 bp open chromatin element is linked to 10 target genes and is bound by 95 transcription factors.

Linked Genes

10 genes

Gene	Expression	Dist. to TSS	Distance	Link type
PLEKHM2		7.1 kb	Proximal	Proximity
DDI2		59.7 kb	Distal	Multiome
FBLIM1		80.8 kb	Distal	Multiome
UQCRHL		130.5 kb	Distal	Multiome
DNAJC16		150.3 kb	Distal	Multiome
CASP9		152.9 kb	Distal	Multiome
SPEN		158.9 kb	Distal	Multiome
SPEN-AS1		171.0 kb	Distal	Multiome
EFHD2		267.3 kb	Distal	Multiome
ZBTB17		298.9 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

95 transcription factors

ADNP 2 datasets

ChIP K-562 ENCSR440VKE.ADNP.K-562 322 bp overlap

ChIP K562 ENCFF492SKF 738 bp overlap

ARID1B 2 datasets

ChIP K-562 ENCSR822CCM.ARID1B.K-562 330 bp overlap

ChIP K562 ENCFF938UXQ 419 bp overlap

ChIP K-562 ENCSR155KHM.ARNT.K-562 291 bp overlap

BCL11A 5 datasets

ChIP CD34_Day5_30min GSE104676.BCL11A.CD34_Day5_30min 87 bp overlap

ChIP CD34_Day5_30min GSE104676.BCL11A.CD34_Day5_30min 53 bp overlap

ChIP CD34_Day9_30min GSE104676.BCL11A.CD34_Day9_30min 54 bp overlap

ChIP CD34_Day9_30min GSE104676.BCL11A.CD34_Day9_30min 55 bp overlap

ChIP HUDEP-2_30min GSE104676.BCL11A.HUDEP-2_30min 117 bp overlap

CBFA2T2 2 datasets

ChIP K-562 ENCSR699PVC.CBFA2T2.K-562 343 bp overlap

ChIP K562 ENCFF963TXY 405 bp overlap

CBFA2T3 4 datasets

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 509 bp overlap

ChIP K-562 GSE142227.CBFA2T3.K-562 304 bp overlap

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 58 bp overlap

ChIP K562 ENCFF673OEZ 558 bp overlap

ChIP K562 ENCFF008KGK 160 bp overlap

ChIP K562 ENCFF410AQU 215 bp overlap

CBX5 2 datasets

ChIP K-562 ENCSR272JAT.CBX5.K-562 119 bp overlap

ChIP K562 ENCFF188CYP 110 bp overlap

CHD4 2 datasets

ChIP K562 ENCFF933NKI 597 bp overlap

ChIP K562 ENCFF933NKI 496 bp overlap

ChIP K562 ENCFF775HUO 268 bp overlap

ChIP K-562 ENCSR000EWJ.E2F6.K-562 205 bp overlap

ChIP K562 ENCFF622HMZ 529 bp overlap

ChIP K562 ENCFF113OPQ 451 bp overlap

EHMT2 1 dataset

ChIP K562 ENCFF053BWO 385 bp overlap

EOMES 2 datasets

Motif DE_48h DE_48h-EOMES_MA0800.2 9 bp overlap

ChIP hESC GSE26097.EOMES.hESC 284 bp overlap

ETV2::FOXI1 1 dataset

Motif DE_48h DE_48h-ETV2FOXI1_MA1942.2 11 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 790 bp overlap

ChIP DE DE-FOXA2-2 688 bp overlap

FOXM1 1 dataset

ChIP K562 ENCFF255RHV 411 bp overlap

GABPA 1 dataset

ChIP K-562 ENCSR000BLO.GABPA.K-562 153 bp overlap

GATA1 10 datasets

ChIP CD34_Day7_30min GSE104676.GATA1.CD34_Day7_30min 177 bp overlap

ChIP CD34_ERYTH_BIO GSE29194.GATA1.CD34_ERYTH_BIO 124 bp overlap

ChIP HUDEP-2_30min GSE104676.GATA1.HUDEP-2_30min 180 bp overlap

ChIP K-562 GSE107726.GATA1.K-562 181 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 236 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 240 bp overlap

ChIP erythroblast ENCFF867JAR 292 bp overlap

ChIP erythroblast ENCSR000EXP.GATA1.erythroblast 661 bp overlap

ChIP erythroid_Don001 GSE137982.GATA1.erythroid_Don001 293 bp overlap

ChIP erythroid_Don003 GSE137982.GATA1.erythroid_Don003 204 bp overlap

GATA2 7 datasets

ChIP CD34_ACY957 GSE60792.GATA2.CD34_ACY957 141 bp overlap

Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap

ChIP K-562 ENCSR000BKM.GATA2.K-562 257 bp overlap

ChIP K-562 ENCSR000EWG.GATA2.K-562 161 bp overlap

ChIP K562 ENCFF088XQT 411 bp overlap

ChIP K562 ENCFF513FTZ 301 bp overlap

ChIP K562 ENCFF544PCK 251 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 790 bp overlap

ChIP DE DE-GATA4-2 790 bp overlap

Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap

GATA5 1 dataset

Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap

GATA6 10 datasets

ChIP DE DE-GATA6-1 790 bp overlap

ChIP DE DE-GATA6-2 790 bp overlap

Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 645 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 790 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 790 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 790 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 790 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 790 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 790 bp overlap

GFI1B 1 dataset

ChIP K-562 ENCSR509GDT.GFI1B.K-562 112 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 222 bp overlap

GTF2I 1 dataset

ChIP K562 ENCFF539BYI 158 bp overlap

Gata3 1 dataset

Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap

Motif DE_48h DE_48h-Gli1_MA1990.2 10 bp overlap

Motif DE_48h DE_48h-Gli2_MA0734.4 9 bp overlap

HDAC1 3 datasets

ChIP K-562 ENCSR711VWL.HDAC1.K-562 212 bp overlap

ChIP K562 ENCFF928TKZ 270 bp overlap

ChIP K562 ENCFF968WBH 521 bp overlap

HDAC2 4 datasets

ChIP K-562 ENCSR075HTM.HDAC2.K-562 247 bp overlap

ChIP K-562 ENCSR893WSB.HDAC2.K-562 329 bp overlap

ChIP K562 ENCFF744ALD 379 bp overlap

ChIP K562 ENCFF889DON 311 bp overlap

ChIP K562 ENCFF783OCM 81 bp overlap

HNRNPK 2 datasets

ChIP Hep-G2 GSE120104.HNRNPK.Hep-G2 253 bp overlap

ChIP Hep-G2 ENCSR519QAA.HNRNPK.Hep-G2 268 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 443 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 348 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 420 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 436 bp overlap

KDM1A 8 datasets

ChIP K-562 ENCSR908CMW.KDM1A.K-562 478 bp overlap

ChIP K-562 ENCSR360HRA.KDM1A.K-562 370 bp overlap

ChIP K-562 GSE117944.KDM1A.K-562 354 bp overlap

ChIP K-562 ENCSR000ATX.KDM1A.K-562 258 bp overlap

ChIP K-562_Wnt GSE117944.KDM1A.K-562_Wnt 377 bp overlap

ChIP K562 ENCFF128TYE 407 bp overlap

ChIP K562 ENCFF133OLU 354 bp overlap

ChIP K562 ENCFF934ZRG 220 bp overlap

ChIP erythroid_R3R4 GSE43625.KLF1.erythroid_R3R4 59 bp overlap

LDB1 2 datasets

ChIP HEP GSE52637.LDB1.HEP 233 bp overlap

ChIP K-562 GSE142227.LDB1.K-562 432 bp overlap

ChIP K562 ENCFF524IJO 397 bp overlap

ChIP K562 ENCFF880VZB 117 bp overlap

Mecom 1 dataset

Motif DE_48h DE_48h-Mecom_MA0029.2 11 bp overlap

NCAPH2 2 datasets

ChIP RMG-I GSE120058.NCAPH2.RMG-I 432 bp overlap

ChIP RMG-I_ARID1A-KO GSE120058.NCAPH2.RMG-I_ARID1A-KO 268 bp overlap

NCOR1 6 datasets

ChIP K-562 ENCSR298JCG.NCOR1.K-562 235 bp overlap

ChIP K-562 ENCSR910JAI.NCOR1.K-562 271 bp overlap

ChIP K-562 ENCSR798ILC.NCOR1.K-562 275 bp overlap

ChIP K562 ENCFF359DNT 411 bp overlap

ChIP K562 ENCFF788MPU 281 bp overlap

ChIP K562 ENCFF866HRM 309 bp overlap

ChIP ProEs GSE59087.NFE2.ProEs 102 bp overlap

NFIC 2 datasets

ChIP K-562 ENCSR796ITY.NFIC.K-562 209 bp overlap

ChIP K562 ENCFF167YID 278 bp overlap

ChIP K-562 GSE26439.NFYA.K-562 239 bp overlap

NR2C2 1 dataset

ChIP K562 ENCFF902UIK 405 bp overlap

NR2F2 1 dataset

ChIP K-562 ENCSR000BRS.NR2F2.K-562 128 bp overlap

Motif DE_48h DE_48h-OSR2_MA1646.2 8 bp overlap

ChIP K562 ENCFF772SGA 365 bp overlap

PHF21A 1 dataset

ChIP K562 ENCFF088QME 321 bp overlap

POLR2A 2 datasets

ChIP H1 ENCFF833NJP 411 bp overlap

ChIP K562 ENCFF514URW 405 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 346 bp overlap

Prdm5 1 dataset

Motif DE_48h DE_48h-Prdm5_MA1999.2 11 bp overlap

RBM25 1 dataset

ChIP K-562 ENCSR791OZM.RBM25.K-562 54 bp overlap

RCOR1 2 datasets

ChIP K562 ENCFF721RTS 345 bp overlap

ChIP keratinocyte_diff GSE57702.RCOR1.keratinocyte_diff 197 bp overlap

ChIP K562 ENCFF653BQJ 611 bp overlap

SETDB1 3 datasets

ChIP HEK293 ENCFF676PLV 285 bp overlap

ChIP HEK293 ENCSR348AGV.SETDB1.HEK293 179 bp overlap

ChIP U2OS ENCSR000EYD.SETDB1.U2OS 179 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 583 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 424 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 319 bp overlap

SMAD2_3 4 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 505 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 445 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 516 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 610 bp overlap

SMAD4 2 datasets

ChIP K562 ENCFF316DFN 371 bp overlap

ChIP K562 ENCFF628RBP 540 bp overlap

SMARCA4 2 datasets

ChIP K562 ENCFF506JCB 192 bp overlap

ChIP K562 ENCFF506JCB 384 bp overlap

SMARCA5 1 dataset

ChIP K562 ENCFF936KHY 101 bp overlap

SMARCE1 1 dataset

ChIP K562 ENCFF690CFF 517 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 443 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 467 bp overlap

ChIP K562 ENCFF059YCJ 395 bp overlap

ChIP K562 ENCFF088XXV 625 bp overlap

SPI1 2 datasets

ChIP EM-3 GSE128834.SPI1.EM-3 158 bp overlap

ChIP KG-1 GSE128834.SPI1.KG-1 219 bp overlap

STAT5A 1 dataset

ChIP K562 ENCFF226BTJ 341 bp overlap

TAL1 13 datasets

ChIP CD34 GSE52924.TAL1.CD34 202 bp overlap

ChIP HSPC-CD34pos GSE93372.TAL1.HSPC-CD34pos 162 bp overlap

ChIP K-562 ENCSR106FRG.TAL1.K-562 254 bp overlap

ChIP K-562 GSE107726.TAL1.K-562 291 bp overlap

ChIP K-562 ENCSR000EHB.TAL1.K-562 311 bp overlap

ChIP K-562_dCas9-KRAB GSE132212.TAL1.K-562_dCas9-KRAB 175 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.TAL1.K-562_dCas9-LSD1 252 bp overlap

ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 225 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 305 bp overlap

ChIP K562 ENCFF620GMX 366 bp overlap

ChIP K562 ENCFF661CCK 179 bp overlap

ChIP ProEs GSE59087.TAL1.ProEs 256 bp overlap

ChIP erythroid GSE42390.TAL1.erythroid 296 bp overlap

TAL1_SCL 1 dataset

ChIP Jurkat GSE25000.TAL1_SCL.Jurkat 105 bp overlap

Motif DE_48h DE_48h-TBR1_MA0802.2 9 bp overlap

TBX20 1 dataset

Motif DE_48h DE_48h-TBX20_MA0689.1 11 bp overlap

Motif DE_48h DE_48h-TBX3_MA1566.3 9 bp overlap

TCF12 5 datasets

ChIP H1 ENCFF203EBH 251 bp overlap

ChIP K-562 ENCSR744WOO.TCF12.K-562 302 bp overlap

ChIP K562 ENCFF909RDY 397 bp overlap

ChIP K562 ENCFF931DJY 396 bp overlap

ChIP WA01 ENCSR000BIT.TCF12.WA01 110 bp overlap

TCF3 2 datasets

ChIP K-562 ENCSR970OJY.TCF3.K-562 196 bp overlap

ChIP K562 ENCFF319QZT 212 bp overlap

TEAD1 1 dataset

ChIP K562 ENCFF254RJL 336 bp overlap

TEAD4 2 datasets

ChIP H1 ENCFF778PAX 245 bp overlap

ChIP K562 ENCFF673NIK 129 bp overlap

TRIM24 4 datasets

ChIP K-562 ENCSR907MZR.TRIM24.K-562 412 bp overlap

ChIP K-562 ENCSR957LDM.TRIM24.K-562 345 bp overlap

ChIP K562 ENCFF284DKY 207 bp overlap

ChIP K562 ENCFF616RIL 490 bp overlap

TRIM28 7 datasets

ChIP HEK293 ENCFF582MWI 286 bp overlap

ChIP K-562 ENCSR000EVY.TRIM28.K-562 406 bp overlap

ChIP K-562 ENCSR474CVP.TRIM28.K-562 334 bp overlap

ChIP K-562 ENCSR000BRW.TRIM28.K-562 282 bp overlap

ChIP K562 ENCFF429WPG 115 bp overlap

ChIP K562 ENCFF429WPG 124 bp overlap

ChIP K562 ENCFF671NCI 776 bp overlap

TRPS1 1 dataset

Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap

Motif DE_48h DE_48h-Tbx6_MA1567.3 9 bp overlap

USF1 2 datasets

ChIP K-562 ENCSR000BKT.USF1.K-562 209 bp overlap

ChIP K562 ENCFF633EZB 265 bp overlap

ChIP K-562 ENCSR000EHG.USF2.K-562 130 bp overlap

XRCC3 2 datasets

ChIP K-562 ENCSR997NGQ.XRCC3.K-562 250 bp overlap

ChIP K562 ENCFF536TLC 361 bp overlap

ZBTB7A 2 datasets

ChIP HUDEP-2 GSE103445.ZBTB7A.HUDEP-2 428 bp overlap

ChIP K-562 GSE103445.ZBTB7A.K-562 58 bp overlap

ChIP K562 ENCFF795CMH 472 bp overlap

ZNF143 2 datasets

ChIP GM12878 ENCSR936XTK.ZNF143.GM12878 213 bp overlap

ChIP K-562 ENCSR000EGP.ZNF143.K-562 136 bp overlap

ZNF281 1 dataset

ChIP K562 ENCFF594VNM 471 bp overlap

ZNF316 3 datasets

ChIP K-562 ENCSR200JYP.ZNF316.K-562 515 bp overlap

ChIP K562 ENCFF281INV 646 bp overlap

ChIP K562 ENCFF838QCD 420 bp overlap

ZNF677 1 dataset

Motif DE_48h DE_48h-ZNF677_MA2101.1 12 bp overlap

ZNF708 1 dataset

Motif DE_48h DE_48h-ZNF708_MA1730.2 9 bp overlap

Zfp335 1 dataset

Motif DE_48h DE_48h-Zfp335_MA2002.2 7 bp overlap