chr6 : 49,713,359 – 49,713,831

472 bp 88 TFs 1 linked gene

This 472 bp open chromatin element is linked to CRISP2 and is bound by 88 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
CRISP2		at TSS	At TSS	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

88 transcription factors

AR 2 datasets

ChIP MCF-7 GSE48930.AR.MCF-7 182 bp overlap

ChIP MDA-MB-453 ERP003503.AR.MDA-MB-453 171 bp overlap

ARNT 1 dataset

ChIP SK-MEL-28 GSE85352.ARNT.SK-MEL-28 239 bp overlap

ARNT::HIF1A 2 datasets

Motif DE_12h DE_12h-ARNTHIF1A_MA0259.2 5 bp overlap

Motif ES_0h ES_0h-ARNTHIF1A_MA0259.2 5 bp overlap

ARNTL 1 dataset

ChIP U2OS_DMSO GSE85096.ARNTL.U2OS_DMSO 122 bp overlap

ATF2 1 dataset

ChIP HepG2 ENCFF955VER 381 bp overlap

Arnt 1 dataset

Motif DE_12h DE_12h-Arnt_MA0004.1 6 bp overlap

BRD2 1 dataset

ChIP HUVEC-C GSE60171.BRD2.HUVEC-C 311 bp overlap

BRD4 4 datasets

ChIP SUM159PT_KO GSE131097.BRD4.SUM159PT_KO 228 bp overlap

ChIP SUM159PT_scramble GSE131097.BRD4.SUM159PT_scramble 317 bp overlap

ChIP hESC GSE33281.BRD4.hESC 237 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 190 bp overlap

CBFB 1 dataset

ChIP ME-1 GSE46044.CBFB.ME-1 284 bp overlap

CLOCK 1 dataset

Motif DE_12h DE_12h-CLOCK_MA0819.3 7 bp overlap

CREB1 2 datasets

ChIP H1 ENCFF955PMP 321 bp overlap

ChIP WA01 ENCSR000BSN.CREB1.WA01 247 bp overlap

CREB3 2 datasets

Motif DE_12h DE_12h-CREB3_MA0638.2 12 bp overlap

Motif ES_0h ES_0h-CREB3_MA0638.2 12 bp overlap

CREB3L4 4 datasets

Motif DE_12h DE_12h-CREB3L4_MA1474.2 10 bp overlap

Motif DE_12h DE_12h-CREB3L4_MA1475.2 9 bp overlap

Motif ES_0h ES_0h-CREB3L4_MA1474.2 10 bp overlap

Motif ES_0h ES_0h-CREB3L4_MA1475.2 9 bp overlap

CREM 2 datasets

Motif DE_12h DE_12h-CREM_MA0609.3 10 bp overlap

Motif ES_0h ES_0h-CREM_MA0609.3 10 bp overlap

CTCF 1 dataset

ChIP SUM159 GSE46055.CTCF.SUM159 156 bp overlap

Creb3l2 1 dataset

Motif DE_12h DE_12h-Creb3l2_MA0608.1 9 bp overlap

E2F6 2 datasets

ChIP H1 ENCFF785DWK 445 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 409 bp overlap

EED 1 dataset

ChIP ProEs GSE59087.EED.ProEs 207 bp overlap

EGR1 2 datasets

Motif DE_12h DE_12h-EGR1_MA0162.5 10 bp overlap

Motif ES_0h ES_0h-EGR1_MA0162.5 10 bp overlap

EPAS1 2 datasets

ChIP 501-mel GSE95280.EPAS1.501-mel 288 bp overlap

Motif ES_0h ES_0h-EPAS1_MA2325.1 9 bp overlap

ERF::FOXO1 1 dataset

Motif DE_12h DE_12h-ERFFOXO1_MA1936.2 12 bp overlap

ERG 1 dataset

ChIP MCF-7 GSE23730.ERG.MCF-7 258 bp overlap

ESR1 9 datasets

ChIP Ishikawa GSE99905.ESR1.Ishikawa 275 bp overlap

ChIP Ishikawa_E2-1h GSE129803.ESR1.Ishikawa_E2-1h 256 bp overlap

ChIP Ishikawa_ETV4-KO1_Mili GSE129803.ESR1.Ishikawa_ETV4-KO1_Mili 148 bp overlap

ChIP Ishikawa_siETV4-72h GSE129803.ESR1.Ishikawa_siETV4-72h 326 bp overlap

ChIP Ishikawa_siNTC-72h GSE129803.ESR1.Ishikawa_siNTC-72h 296 bp overlap

ChIP Ishikawa_siNTC-96h GSE129803.ESR1.Ishikawa_siNTC-96h 233 bp overlap

ChIP MCF-7_PaPE-1 GSE93510.ESR1.MCF-7_PaPE-1 382 bp overlap

ChIP MCF-7_Sat-H3B-6545 GSE115607.ESR1.MCF-7_Sat-H3B-6545 197 bp overlap

ChIP MDA-MB-134-VI_ESTROGEN GSE51022.ESR1.MDA-MB-134-VI_ESTROGEN 245 bp overlap

ETV1 1 dataset

Motif DE_12h DE_12h-ETV1_MA0761.3 9 bp overlap

EZH2 6 datasets

ChIP A-673 ENCSR179SAO.EZH2.A-673 388 bp overlap

ChIP LNCaP-abl GSE39459.EZH2.LNCaP-abl 472 bp overlap

ChIP THP-1 GSE135024.EZH2.THP-1 272 bp overlap

ChIP dermal-fibroblast_Transformed GSE126396.EZH2.dermal-fibroblast_Transformed 200 bp overlap

ChIP keratinocyte ENCSR000ARK.EZH2.keratinocyte 185 bp overlap

ChIP keratinocyte ENCSR000ARK.EZH2.keratinocyte 223 bp overlap

FLI1 1 dataset

ChIP TSU-1621MT GSE60477.FLI1.TSU-1621MT 241 bp overlap

GATA2 1 dataset

ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 195 bp overlap

HES2 1 dataset

Motif DE_12h DE_12h-HES2_MA0616.3 9 bp overlap

HES5 1 dataset

Motif DE_12h DE_12h-HES5_MA0821.2 10 bp overlap

HEY1 1 dataset

Motif DE_12h DE_12h-HEY1_MA0823.1 10 bp overlap

HEY2 1 dataset

Motif DE_12h DE_12h-HEY2_MA0649.2 9 bp overlap

HIF1A 1 dataset

ChIP U2OS_trough_DMOG GSE85096.HIF1A.U2OS_trough_DMOG 148 bp overlap

HOXB13 1 dataset

ChIP prostate_P23 GSE130408.HOXB13.prostate_P23 108 bp overlap

IKZF2 1 dataset

Motif DE_12h DE_12h-IKZF2_MA2326.1 6 bp overlap

JUND 1 dataset

ChIP WA01 ENCSR000BKP.JUND.WA01 125 bp overlap

KDM5B 1 dataset

ChIP SUM159 GSE46055.KDM5B.SUM159 201 bp overlap

KDM6B 1 dataset

ChIP CUTLL1 GSE56694.KDM6B.CUTLL1 238 bp overlap

MAF1 1 dataset

ChIP THP-1_macrophage_PMA GSE96800.MAF1.THP-1_macrophage_PMA 163 bp overlap

MAX 2 datasets

Motif DE_12h DE_12h-MAX_MA0058.4 6 bp overlap

ChIP H1 ENCFF914VQY 357 bp overlap

MED1 2 datasets

ChIP MCF-7_SHRARS GSE60270.MED1.MCF-7_SHRARS 137 bp overlap

ChIP MCF-7_SHRARS_E2 GSE60270.MED1.MCF-7_SHRARS_E2 194 bp overlap

MNT 1 dataset

Motif DE_12h DE_12h-MNT_MA0825.2 6 bp overlap

MORC2 1 dataset

ChIP HeLa_V5-MORC2-KO GSE95451.MORC2.HeLa_V5-MORC2-KO 148 bp overlap

MYB 1 dataset

Motif DE_12h DE_12h-MYB_MA0100.4 6 bp overlap

MYC 1 dataset

Motif DE_12h DE_12h-MYC_MA0147.4 8 bp overlap

MYCN 3 datasets

ChIP COG-N-415 GSE138295.MYCN.COG-N-415 419 bp overlap

Motif DE_12h DE_12h-MYCN_MA0104.5 8 bp overlap

ChIP LA-N-5 GSE138295.MYCN.LA-N-5 472 bp overlap

Mlxip 1 dataset

Motif DE_12h DE_12h-Mlxip_MA0622.2 6 bp overlap

NANOG 1 dataset

ChIP HUES-8 GSE109524.NANOG.HUES-8 297 bp overlap

NELFE 1 dataset

ChIP K-562_HS GSE112379.NELFE.K-562_HS 200 bp overlap

NFKB1 1 dataset

ChIP HEK293T GSE129618.NFKB1.HEK293T 201 bp overlap

Npas2 1 dataset

Motif DE_12h DE_12h-Npas2_MA0626.2 8 bp overlap

OGG1 3 datasets

ChIP HEK293 GSE89017.OGG1.HEK293 390 bp overlap

ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 387 bp overlap

ChIP HEK293_60_min GSE89017.OGG1.HEK293_60_min 338 bp overlap

POU5F1 2 datasets

ChIP BG03 GSE21614.POU5F1.BG03 260 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 336 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 296 bp overlap

PRDM15 3 datasets

ChIP Hep-G2 ENCSR011INW.PRDM15.Hep-G2 259 bp overlap

ChIP HepG2 ENCFF259LUZ 373 bp overlap

ChIP WTC11 ENCFF108TMF 112 bp overlap

PTBP1 2 datasets

ChIP Hep-G2 ENCSR156APP.PTBP1.Hep-G2 170 bp overlap

ChIP Hep-G2 GSE120104.PTBP1.Hep-G2 170 bp overlap

Prdm15 1 dataset

Motif DE_12h DE_12h-Prdm15_MA1616.2 11 bp overlap

RAD21 1 dataset

ChIP HCT-116 GSE131606.RAD21.HCT-116 324 bp overlap

RELA 1 dataset

ChIP MCF-7_IL1b_45m GSE67295.RELA.MCF-7_IL1b_45m 157 bp overlap

RNF2 2 datasets

ChIP WA09 GSE105028.RNF2.WA09 265 bp overlap

ChIP WA09_heat-shock GSE105028.RNF2.WA09_heat-shock 304 bp overlap

RORC 1 dataset

ChIP HCC70 GSE126380.RORC.HCC70 218 bp overlap

RUNX1 2 datasets

ChIP AML_Blast GSE60130.RUNX1.AML_Blast 181 bp overlap

ChIP CD34 GSE64862.RUNX1.CD34 181 bp overlap

RUVBL2 1 dataset

ChIP U2OS GSE130602.RUVBL2.U2OS 442 bp overlap

RXR 1 dataset

ChIP TSU-1621MT GSE60477.RXR.TSU-1621MT 201 bp overlap

SIRT6 1 dataset

ChIP SK-MEL-239_L-C-B GSE102813.SIRT6.SK-MEL-239_L-C-B 170 bp overlap

SOX12 2 datasets

Motif DE_12h DE_12h-SOX12_MA1561.2 10 bp overlap

Motif ES_0h ES_0h-SOX12_MA1561.2 10 bp overlap

SOX14 2 datasets

Motif DE_12h DE_12h-SOX14_MA1562.2 9 bp overlap

Motif ES_0h ES_0h-SOX14_MA1562.2 9 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 254 bp overlap

SOX2 2 datasets

ChIP RENVM GSE49404.SOX2.RENVM 254 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 454 bp overlap

SOX9 2 datasets

Motif DE_12h DE_12h-SOX9_MA0077.2 8 bp overlap

Motif ES_0h ES_0h-SOX9_MA0077.2 8 bp overlap

SP1 1 dataset

ChIP WA01 ENCSR000BIR.SP1.WA01 177 bp overlap

SREBP2 1 dataset

ChIP HCC70 GSE126380.SREBP2.HCC70 265 bp overlap

SRSF3 1 dataset

ChIP K-562 GSE120104.SRSF3.K-562 303 bp overlap

STAT3 1 dataset

ChIP WA01 ERP004237.STAT3.WA01 233 bp overlap

TAF1 1 dataset

ChIP WA01 ENCSR000BHO.TAF1.WA01 152 bp overlap

TP53 1 dataset

ChIP hESC_DIFF GSE39912.TP53.hESC_DIFF 322 bp overlap

USF1 3 datasets

ChIP H1 ENCFF090WVU 241 bp overlap

ChIP SK-N-SH ENCSR000BMF.USF1.SK-N-SH 124 bp overlap

ChIP WA01 ENCSR000BIU.USF1.WA01 209 bp overlap

YY1 1 dataset

ChIP WA01 ENCSR000BKD.YY1.WA01 127 bp overlap

ZBTB26 1 dataset

Motif DE_12h DE_12h-ZBTB26_MA1579.2 8 bp overlap

ZBTB33 2 datasets

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 472 bp overlap

ChIP K562 ENCFF875HLX 444 bp overlap

ZBTB48 2 datasets

ChIP U2OS GSE96776.ZBTB48.U2OS 396 bp overlap

ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 383 bp overlap

ZBTB6 1 dataset

Motif DE_12h DE_12h-ZBTB6_MA1581.2 9 bp overlap

ZBTB7A 2 datasets

ChIP VCaP_DHT GSE123089.ZBTB7A.VCaP_DHT 297 bp overlap

ChIP VCaP_FBS GSE123089.ZBTB7A.VCaP_FBS 472 bp overlap

ZFP57 1 dataset

ChIP hESC GSE115387.ZFP57.hESC 115 bp overlap

ZNF3 1 dataset

ChIP K-562 ENCSR195QFV.ZNF3.K-562 196 bp overlap

ZNF417 2 datasets

Motif DE_12h DE_12h-ZNF417_MA1727.2 7 bp overlap

Motif ES_0h ES_0h-ZNF417_MA1727.2 7 bp overlap

ZNF460 1 dataset

Motif DE_12h DE_12h-ZNF460_MA1596.1 16 bp overlap

ZNF572 1 dataset

ChIP Hep-G2 ENCSR663CTC.ZNF572.Hep-G2 308 bp overlap

ZNF737 1 dataset

ChIP Hep-G2 ENCSR127IHN.ZNF737.Hep-G2 177 bp overlap