chr1:93,029,424–93,029,880

chr1 : 93,029,424 – 93,029,880

456 bp 92 TFs 6 linked genes

This 456 bp open chromatin element is linked to 6 target genes and is bound by 92 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
MTF2		49.7 kb	Distal	Multiome
DIPK1A		68.1 kb	Distal	Multiome
TMED5		150.8 kb	Distal	Multiome
CCDC18		151.1 kb	Distal	Multiome
RPL5		197.6 kb	Distal	Multiome
EVI5		244.5 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

92 transcription factors

ARID5B 1 dataset

ChIP Jurkat GSE97512.ARID5B.Jurkat 420 bp overlap

BCL11B 2 datasets

ChIP thymus_CD34neg GSE84677.BCL11B.thymus_CD34neg 300 bp overlap

ChIP thymus_CD34pos GSE84677.BCL11B.thymus_CD34pos 184 bp overlap

BCL6 5 datasets

ChIP OCI-Ly1 GSE29282.BCL6.OCI-Ly1 357 bp overlap

ChIP OCI-Ly1 GSE107920.BCL6.OCI-Ly1 292 bp overlap

ChIP OCI-Ly1_si GSE107920.BCL6.OCI-Ly1_si 207 bp overlap

ChIP OCI-Ly7 GSE44420.BCL6.OCI-Ly7 275 bp overlap

ChIP SU-DHL-4 GSE119038.BCL6.SU-DHL-4 348 bp overlap

BHLHE22 1 dataset

ChIP CAL-1 GSE43876.BHLHE22.CAL-1 229 bp overlap

BRD4 17 datasets

ChIP CD4_JG1 GSE33281.BRD4.CD4_JG1 223 bp overlap

ChIP DND41 GSE54379.BRD4.DND41 456 bp overlap

ChIP DND41_E GSE54379.BRD4.DND41_E 299 bp overlap

ChIP HEK293_sgMYOD GSE129407.BRD4.HEK293_sgMYOD 253 bp overlap

ChIP Jurkat GSE83777.BRD4.Jurkat 456 bp overlap

ChIP KOPT-K1 GSE54379.BRD4.KOPT-K1 456 bp overlap

ChIP KOPT-K1_E GSE54379.BRD4.KOPT-K1_E 240 bp overlap

ChIP MM1-S GSE43743.BRD4.MM1-S 224 bp overlap

ChIP MM1-S_JQ1_150NM GSE49224.BRD4.MM1-S_JQ1_150NM 200 bp overlap

ChIP MM1-S_JQ1_500NM GSE42355.BRD4.MM1-S_JQ1_500NM 275 bp overlap

ChIP MM1-S_JQ1_50NM GSE42355.BRD4.MM1-S_JQ1_50NM 277 bp overlap

ChIP MM1-S_JQ1_5NM GSE42355.BRD4.MM1-S_JQ1_5NM 395 bp overlap

ChIP MM1-S_JQ1_5UM GSE42355.BRD4.MM1-S_JQ1_5UM 285 bp overlap

ChIP MOLT-4_DMSO GSE79288.BRD4.MOLT-4_DMSO 456 bp overlap

ChIP OCI-Ly1_DMSO GSE53601.BRD4.OCI-Ly1_DMSO 408 bp overlap

ChIP OCI-Ly1_JQ1 GSE53601.BRD4.OCI-Ly1_JQ1 231 bp overlap

ChIP SEM GSE83671.BRD4.SEM 436 bp overlap

Bcl11B 1 dataset

Motif DE_48h DE_48h-Bcl11B_MA1989.2 9 bp overlap

ChIP KB_IL GSE52469.CDK6.KB_IL 68 bp overlap

CDK7 3 datasets

ChIP Jurkat GSE83777.CDK7.Jurkat 412 bp overlap

ChIP Jurkat_DMSO GSE60027.CDK7.Jurkat_DMSO 245 bp overlap

ChIP Jurkat_THZ2102 GSE60027.CDK7.Jurkat_THZ2102 207 bp overlap

CDK9 6 datasets

ChIP MM1-S_DMSO GSE42161.CDK9.MM1-S_DMSO 271 bp overlap

ChIP MM1-S_JQ1_5000NM GSE49224.CDK9.MM1-S_JQ1_5000NM 247 bp overlap

ChIP MM1-S_JQ1_500NM GSE42355.CDK9.MM1-S_JQ1_500NM 259 bp overlap

ChIP MM1-S_JQ1_50NM GSE49224.CDK9.MM1-S_JQ1_50NM 320 bp overlap

ChIP MOLT-4_DMSO GSE79288.CDK9.MOLT-4_DMSO 320 bp overlap

ChIP MOLT-4_JQ1 GSE79288.CDK9.MOLT-4_JQ1 410 bp overlap

CTCF 6 datasets

Motif DE_48h DE_48h-CTCF_MA0139.2 15 bp overlap

Motif DE_48h DE_48h-CTCF_MA1930.2 33 bp overlap

ChIP DND-41 ENCFF913MRA 265 bp overlap

ChIP DND41 ENCSR000AQU.CTCF.DND41 161 bp overlap

ChIP endodermal cell ENCFF471YCZ 333 bp overlap

ChIP leukemia_CEBPA-24h GSE142161.CTCF.leukemia_CEBPA-24h 263 bp overlap

CTNNB1 2 datasets

ChIP hiPSC_D2 GSE132532.CTNNB1.hiPSC_D2 239 bp overlap

ChIP hiPSC_TT-neg_D2 GSE132532.CTNNB1.hiPSC_TT-neg_D2 218 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF093OYK 190 bp overlap

ChIP NALM-6 GSE126300.EBF1.NALM-6 384 bp overlap

EOMES 2 datasets

Motif DE_48h DE_48h-EOMES_MA0800.2 9 bp overlap

ChIP hESC GSE26097.EOMES.hESC 297 bp overlap

ChIP Jurkat GSE49091.ERG.Jurkat 402 bp overlap

ChIP breast_tumor_BADOUTCOME GSE40867.ESR1.breast_tumor_BADOUTCOME 285 bp overlap

ETS1 6 datasets

ChIP ALL-SIL GSE102209.ETS1.ALL-SIL 229 bp overlap

ChIP CD4-pos GSE146787.ETS1.CD4-pos 295 bp overlap

ChIP CTV-1_DSG GSE128835.ETS1.CTV-1_DSG 413 bp overlap

ChIP CTV-1_DSG_SPI1-mut GSE128835.ETS1.CTV-1_DSG_SPI1-mut 401 bp overlap

ChIP THP-6_shCtrl GSE138516.ETS1.THP-6_shCtrl 456 bp overlap

ChIP THP-6_shEts1 GSE138516.ETS1.THP-6_shEts1 456 bp overlap

EZH2 3 datasets

ChIP Jurkat GSE147198.EZH2.Jurkat 296 bp overlap

ChIP Jurkat_KO GSE147198.EZH2.Jurkat_KO 452 bp overlap

ChIP WSU-DLCL2 GSE45982.EZH2.WSU-DLCL2 180 bp overlap

FLI1 3 datasets

ChIP CTV-1_DSG GSE128835.FLI1.CTV-1_DSG 318 bp overlap

ChIP CTV-1_DSG_SPI1-mut GSE128835.FLI1.CTV-1_DSG_SPI1-mut 329 bp overlap

ChIP SEM GSE117864.FLI1.SEM 228 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 403 bp overlap

ChIP DE DE-FOXA2-2 456 bp overlap

FOXP1 2 datasets

ChIP SU-DHL-6 ERP010999.FOXP1.SU-DHL-6 214 bp overlap

ChIP U2932 ERP010999.FOXP1.U2932 98 bp overlap

GATA2 1 dataset

ChIP K-562 ENCSR000DKA.GATA2.K-562 306 bp overlap

GATA3 6 datasets

ChIP CD4_TH2 GSE72266.GATA3.CD4_TH2 224 bp overlap

ChIP Jurkat GSE29180.GATA3.Jurkat 456 bp overlap

ChIP Jurkat GSE76181.GATA3.Jurkat 409 bp overlap

ChIP Jurkat GSE68976.GATA3.Jurkat 410 bp overlap

ChIP Jurkat GSE120063.GATA3.Jurkat 416 bp overlap

ChIP thymocyte GSE71751.GATA3.thymocyte 406 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 456 bp overlap

ChIP DE DE-GATA4-2 456 bp overlap

GATA6 9 datasets

ChIP DE DE-GATA6-1 456 bp overlap

ChIP DE DE-GATA6-2 456 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 456 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 456 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 456 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 418 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 456 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 456 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 429 bp overlap

HDAC3 1 dataset

ChIP RH4_DMSO-6H GSE116344.HDAC3.RH4_DMSO-6H 203 bp overlap

Hnf1A 1 dataset

Motif DE_48h DE_48h-Hnf1A_MA1991.2 10 bp overlap

IKZF1 1 dataset

ChIP pre-B-cell GSE107886.IKZF1.pre-B-cell 194 bp overlap

IKZF3 1 dataset

ChIP pre-B-cell GSE107886.IKZF3.pre-B-cell 159 bp overlap

IRF4 3 datasets

ChIP BC-3 GSE132777.IRF4.BC-3 85 bp overlap

ChIP NCI-H929 GSE56857.IRF4.NCI-H929 128 bp overlap

ChIP T-cell GSE136853.IRF4.T-cell 393 bp overlap

KDM1A 2 datasets

ChIP OCI-Ly1_si GSE107920.KDM1A.OCI-Ly1_si 100 bp overlap

ChIP SU-DHL-4 GSE119038.KDM1A.SU-DHL-4 198 bp overlap

KMT2A 3 datasets

ChIP CCRF-CEM GSE83671.KMT2A.CCRF-CEM 376 bp overlap

ChIP L826 GSE83671.KMT2A.L826 164 bp overlap

ChIP blood_cord GSE83671.KMT2A.blood_cord 131 bp overlap

ChIP Jurkat GSE94391.LMO1.Jurkat 383 bp overlap

ChIP CCRF-CEM GSE33850.LMO2.CCRF-CEM 52 bp overlap

Motif DE_48h DE_48h-Lef1_MA0768.3 8 bp overlap

ChIP P493-6_24HR GSE125863.MAX.P493-6_24HR 98 bp overlap

ChIP SEM GSE83671.MED.SEM 371 bp overlap

MED1 6 datasets

ChIP Jurkat GSE59657.MED1.Jurkat 327 bp overlap

ChIP MM1-S_JQ1 GSE42161.MED1.MM1-S_JQ1 286 bp overlap

ChIP MM1-S_JQ1_500NM GSE42355.MED1.MM1-S_JQ1_500NM 370 bp overlap

ChIP MM1-S_JQ1_50NM GSE49224.MED1.MM1-S_JQ1_50NM 362 bp overlap

ChIP MM1-S_JQ1_5NM GSE49224.MED1.MM1-S_JQ1_5NM 218 bp overlap

ChIP OCI-Ly1 GSE53601.MED1.OCI-Ly1 403 bp overlap

MEF2B 1 dataset

ChIP tonsil GSE110682.MEF2B.tonsil 197 bp overlap

MEIS1 2 datasets

Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap

ChIP SEM GSE38339.MEIS1.SEM 183 bp overlap

ChIP pre-B-cell GSE107886.MTA2.pre-B-cell 160 bp overlap

ChIP CD4_TH2 GSE72266.MYB.CD4_TH2 189 bp overlap

ChIP CD4_Th1 GSE72266.MYB.CD4_Th1 160 bp overlap

ChIP Jurkat GSE59657.MYB.Jurkat 456 bp overlap

ChIP MOLT-3 GSE59657.MYB.MOLT-3 456 bp overlap

ChIP PF-382 GSE94000.MYB.PF-382 373 bp overlap

ChIP SEM GSE117864.MYB.SEM 237 bp overlap

ChIP Jurkat GSE83777.MYC.Jurkat 193 bp overlap

ChIP MM1-S_DMSO GSE36354.MYC.MM1-S_DMSO 191 bp overlap

ChIP MM1-S_DMSO GSE36354.MYC.MM1-S_DMSO 175 bp overlap

ChIP P493-6_scramble-shRNA GSE101853.MYC.P493-6_scramble-shRNA 174 bp overlap

ChIP LA-N-5 GSE138295.MYCN.LA-N-5 165 bp overlap

NCOR1 1 dataset

ChIP OCI-Ly1 GSE29282.NCOR1.OCI-Ly1 216 bp overlap

NCOR2 1 dataset

ChIP OCI-Ly1 GSE29282.NCOR2.OCI-Ly1 308 bp overlap

NOTCH1 4 datasets

ChIP CUTLL1 GSE29600.NOTCH1.CUTLL1 414 bp overlap

ChIP HPBALL GSE39263.NOTCH1.HPBALL 456 bp overlap

ChIP THP-6_shCtrl GSE138516.NOTCH1.THP-6_shCtrl 438 bp overlap

ChIP THP-6_shEts1 GSE138516.NOTCH1.THP-6_shEts1 456 bp overlap

NR3C1 3 datasets

ChIP ALL_DEX GSE109946.NR3C1.ALL_DEX 197 bp overlap

ChIP NALM-6 GSE67046.NR3C1.NALM-6 436 bp overlap

ChIP NALM-6_CASP1 GSE67046.NR3C1.NALM-6_CASP1 339 bp overlap

PAX5 3 datasets

ChIP NALM-6 GSE126300.PAX5.NALM-6 382 bp overlap

ChIP NALM-6 GSE115764.PAX5.NALM-6 196 bp overlap

ChIP OCI-Ly7 GSE69558.PAX5.OCI-Ly7 225 bp overlap

ChIP RCH-ACV GSE85988.PBX1.RCH-ACV 333 bp overlap

PBX1-2-3 1 dataset

ChIP 697 GSE138031.PBX1-2-3.697 162 bp overlap

PHOX2A 1 dataset

Motif DE_48h DE_48h-PHOX2A_MA0713.1 11 bp overlap

POU2F2 1 dataset

ChIP HNPC_UNDIF GSE74814.POU2F2.HNPC_UNDIF 135 bp overlap

RBPJ 3 datasets

ChIP CUTLL1 GSE29600.RBPJ.CUTLL1 406 bp overlap

ChIP THP-6_shCtrl GSE138516.RBPJ.THP-6_shCtrl 456 bp overlap

ChIP THP-6_shEts1 GSE138516.RBPJ.THP-6_shEts1 456 bp overlap

ChIP BJAB GSE117250.RELA.BJAB 245 bp overlap

RUNX1 10 datasets

ChIP 697 GSE138031.RUNX1.697 271 bp overlap

ChIP ALL-SIL GSE102209.RUNX1.ALL-SIL 381 bp overlap

ChIP BCP-ALL_patient1 GSE109377.RUNX1.BCP-ALL_patient1 287 bp overlap

ChIP HL-60 GSE107553.RUNX1.HL-60 200 bp overlap

ChIP Jurkat GSE68976.RUNX1.Jurkat 455 bp overlap

ChIP Jurkat GSE76181.RUNX1.Jurkat 380 bp overlap

ChIP Jurkat GSE29180.RUNX1.Jurkat 240 bp overlap

ChIP Jurkat GSE42575.RUNX1.Jurkat 322 bp overlap

ChIP NALM-6 GSE126300.RUNX1.NALM-6 403 bp overlap

ChIP NALM-6 GSE109377.RUNX1.NALM-6 185 bp overlap

RUNX1-3 1 dataset

ChIP Jurkat GSE17954.RUNX1-3.Jurkat 332 bp overlap

RUNX2 3 datasets

Motif DE_48h DE_48h-RUNX2_MA0511.2 9 bp overlap

ChIP Karpas-45 GSE151819.RUNX2.Karpas-45 307 bp overlap

ChIP PER-117 GSE151819.RUNX2.PER-117 396 bp overlap

RUNX3 2 datasets

Motif DE_48h DE_48h-RUNX3_MA0684.3 8 bp overlap

ChIP GM12878 ENCFF395WHA 282 bp overlap

Runx1 1 dataset

Motif DE_48h DE_48h-Runx1_MA0002.3 9 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 336 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 430 bp overlap

SMAD2_3 4 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 430 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 322 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 227 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 304 bp overlap

SMARCA4 6 datasets

ChIP CTV-1_DSG GSE128835.SMARCA4.CTV-1_DSG 456 bp overlap

ChIP CTV-1_DSG_SPI1-mut GSE128835.SMARCA4.CTV-1_DSG_SPI1-mut 409 bp overlap

ChIP CTV-1_FLAG GSE128835.SMARCA4.CTV-1_FLAG 333 bp overlap

ChIP CTV-1_FLAG_SPI1-mut GSE128835.SMARCA4.CTV-1_FLAG_SPI1-mut 338 bp overlap

ChIP CTV-1_delA GSE128835.SMARCA4.CTV-1_delA 339 bp overlap

ChIP CTV-1_delQ GSE128835.SMARCA4.CTV-1_delQ 337 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 290 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 327 bp overlap

SPI1 15 datasets

ChIP CD34_FETAL GSE70660.SPI1.CD34_FETAL 237 bp overlap

ChIP CTV-1_FLAG_15perc GSE128835.SPI1.CTV-1_FLAG_15perc 347 bp overlap

ChIP CTV-1_delA GSE128835.SPI1.CTV-1_delA 326 bp overlap

ChIP CTV-1_delQ GSE128835.SPI1.CTV-1_delQ 341 bp overlap

ChIP CTV-1_delQA GSE128835.SPI1.CTV-1_delQA 339 bp overlap

ChIP CTV-1_mock GSE128835.SPI1.CTV-1_mock 255 bp overlap

ChIP EM-3 GSE128834.SPI1.EM-3 165 bp overlap

ChIP GM12878 ENCFF134LCP 297 bp overlap

ChIP KG-1 GSE128834.SPI1.KG-1 201 bp overlap

ChIP NCI-H929 GSE56857.SPI1.NCI-H929 130 bp overlap

ChIP OCI-Ly7 GSE69558.SPI1.OCI-Ly7 345 bp overlap

ChIP RS4-11 GSE71616.SPI1.RS4-11 239 bp overlap

ChIP RS4-11_DEX GSE71616.SPI1.RS4-11_DEX 337 bp overlap

ChIP monocyte GSE31621.SPI1.monocyte 132 bp overlap

ChIP monocyte_MACROPHAGE GSE31621.SPI1.monocyte_MACROPHAGE 142 bp overlap

ChIP OCI-Ly3_SHCTR GSE56857.SPIB.OCI-Ly3_SHCTR 203 bp overlap

STAT3 1 dataset

ChIP OCI-Ly7 GSE50723.STAT3.OCI-Ly7 151 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 282 bp overlap

TAL1 5 datasets

ChIP CCRF-CEM GSE33850.TAL1.CCRF-CEM 236 bp overlap

ChIP Jurkat GSE29180.TAL1.Jurkat 370 bp overlap

ChIP MOLT-3 GSE59657.TAL1.MOLT-3 456 bp overlap

ChIP PRIMA2 GSE33850.TAL1.PRIMA2 154 bp overlap

ChIP PRIMA5 GSE33850.TAL1.PRIMA5 456 bp overlap

TAL1_SCL 1 dataset

ChIP erythroid GSE25000.TAL1_SCL.erythroid 212 bp overlap

Motif DE_48h DE_48h-TBR1_MA0802.2 9 bp overlap

Motif DE_48h DE_48h-TBX1_MA0805.1 8 bp overlap

TBX15 1 dataset

Motif DE_48h DE_48h-TBX15_MA0803.1 8 bp overlap

TBX18 1 dataset

Motif DE_48h DE_48h-TBX18_MA1565.2 9 bp overlap

TBX19 1 dataset

Motif DE_48h DE_48h-TBX19_MA0804.2 17 bp overlap

Motif DE_48h DE_48h-TBX2_MA0688.2 9 bp overlap

TBX20 1 dataset

Motif DE_48h DE_48h-TBX20_MA0689.1 11 bp overlap

TBX21 2 datasets

Motif DE_48h DE_48h-TBX21_MA0690.3 10 bp overlap

ChIP Th1_CD3-CD28_donor2 GSE81881.TBX21.Th1_CD3-CD28_donor2 235 bp overlap

Motif DE_48h DE_48h-TBX3_MA1566.3 9 bp overlap

Motif DE_48h DE_48h-TBX4_MA0806.1 8 bp overlap

Motif DE_48h DE_48h-TBX5_MA0807.1 8 bp overlap

TCF12 2 datasets

ChIP CCRF-CEM GSE33850.TCF12.CCRF-CEM 110 bp overlap

ChIP Jurkat GSE29180.TCF12.Jurkat 388 bp overlap

TCF3 6 datasets

ChIP 697_HF GSE138031.TCF3.697_HF 105 bp overlap

ChIP Jurkat GSE29180.TCF3.Jurkat 262 bp overlap

ChIP Kasumi-1 GSE43834.TCF3.Kasumi-1 101 bp overlap

ChIP RCH-ACV GSE85988.TCF3.RCH-ACV 409 bp overlap

ChIP Ramos GSE139810.TCF3.Ramos 434 bp overlap

ChIP SEM GSE85988.TCF3.SEM 259 bp overlap

TCF3-PBX1 1 dataset

ChIP 697_HF GSE138031.TCF3-PBX1.697_HF 187 bp overlap

TCF4 2 datasets

ChIP CAL-1 GSE76147.TCF4.CAL-1 407 bp overlap

ChIP GEN2-2 GSE76147.TCF4.GEN2-2 401 bp overlap

Motif DE_48h DE_48h-TCF7_MA0769.3 7 bp overlap

TCF7L2 1 dataset

Motif DE_48h DE_48h-TCF7L2_MA0523.2 9 bp overlap

TERF2 1 dataset

ChIP LCL GSE55053.TERF2.LCL 64 bp overlap

Motif DE_48h DE_48h-Tbx6_MA1567.3 9 bp overlap

ZMIZ1 2 datasets

ChIP THP-6_shCtrl GSE138516.ZMIZ1.THP-6_shCtrl 456 bp overlap

ChIP THP-6_shEts1 GSE138516.ZMIZ1.THP-6_shEts1 456 bp overlap

ZNF708 1 dataset

Motif DE_48h DE_48h-ZNF708_MA1730.2 9 bp overlap