chr1 : 84,894,500 – 84,895,091

591 bp 117 TFs 1 linked gene

This 591 bp open chromatin element is linked to LPAR3 and is bound by 117 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
LPAR3		1.3 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

117 transcription factors

AR 1 dataset

ChIP LNCaP GSE80256.AR.LNCaP 307 bp overlap

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 340 bp overlap

BCOR 3 datasets

ChIP WA01 GSE104690.BCOR.WA01 209 bp overlap

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 336 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 335 bp overlap

CEBPD 1 dataset

Motif ES_0h ES_0h-CEBPD_MA0836.3 8 bp overlap

CTCF 1 dataset

ChIP Panc1 ENCFF056JQX 179 bp overlap

E2F2 1 dataset

Motif DE_12h DE_12h-E2F2_MA0864.3 13 bp overlap

EBF3 1 dataset

Motif ES_0h ES_0h-EBF3_MA1637.2 9 bp overlap

EHF 1 dataset

Motif ES_0h ES_0h-EHF_MA0598.4 9 bp overlap

ELF1 1 dataset

Motif ES_0h ES_0h-ELF1_MA0473.4 9 bp overlap

ELF2 1 dataset

Motif ES_0h ES_0h-ELF2_MA1483.3 10 bp overlap

ELF3 1 dataset

Motif ES_0h ES_0h-ELF3_MA0640.3 9 bp overlap

ESR1 1 dataset

ChIP endometrioid-adenocarcinoma_tumor_2 GSE94031.ESR1.endometrioid-adenocarcinoma_tumor_2 403 bp overlap

ETV1 1 dataset

Motif ES_0h ES_0h-ETV1_MA0761.3 9 bp overlap

EWSR1-FLI1 1 dataset

Motif ES_0h ES_0h-EWSR1-FLI1_MA0149.1 18 bp overlap

EZH2 4 datasets

ChIP endothelial cell of umbilical vein ENCFF539AKL 138 bp overlap

ChIP endothelial cell of umbilical vein ENCFF539AKL 591 bp overlap

ChIP endothelial_umbilical-vein ENCSR000ATA.EZH2.endothelial_umbilical-vein 292 bp overlap

ChIP hepatocyte ENCSR384LYW.EZH2.hepatocyte 517 bp overlap

Ebf2 1 dataset

Motif ES_0h ES_0h-Ebf2_MA1604.2 9 bp overlap

Elf5 1 dataset

Motif ES_0h ES_0h-Elf5_MA0136.4 8 bp overlap

Erg 1 dataset

Motif ES_0h ES_0h-Erg_MA0474.4 10 bp overlap

Esrrg 1 dataset

Motif ES_0h ES_0h-Esrrg_MA0643.2 9 bp overlap

FOSL2 1 dataset

Motif ES_0h ES_0h-FOSL2_MA0478.2 10 bp overlap

FOXA1 1 dataset

Motif ES_0h ES_0h-FOXA1_MA0148.5 8 bp overlap

FOXA2 3 datasets

ChIP BJ1-hTERT_FoxHnf1aCoExp GSE90454.FOXA2.BJ1-hTERT_FoxHnf1aCoExp 211 bp overlap

Motif ES_0h ES_0h-FOXA2_MA0047.4 8 bp overlap

ChIP liver_CARN1618 ERP008682.FOXA2.liver_CARN1618 273 bp overlap

FOXA3 1 dataset

Motif ES_0h ES_0h-FOXA3_MA1683.2 7 bp overlap

FOXD1 1 dataset

Motif ES_0h ES_0h-FOXD1_MA0031.2 7 bp overlap

FOXF2 1 dataset

Motif ES_0h ES_0h-FOXF2_MA0030.2 9 bp overlap

FOXG1 1 dataset

Motif ES_0h ES_0h-FOXG1_MA0613.1 8 bp overlap

FOXI1 1 dataset

Motif ES_0h ES_0h-FOXI1_MA0042.2 7 bp overlap

FOXK1 2 datasets

Motif ES_0h ES_0h-FOXK1_MA0852.3 7 bp overlap

ChIP WTC11 ENCFF875IGU 391 bp overlap

FOXK2 1 dataset

Motif ES_0h ES_0h-FOXK2_MA1103.3 7 bp overlap

FOXL1 1 dataset

Motif ES_0h ES_0h-FOXL1_MA0033.2 7 bp overlap

FOXO4 1 dataset

Motif ES_0h ES_0h-FOXO4_MA0848.1 7 bp overlap

FOXO6 1 dataset

Motif ES_0h ES_0h-FOXO6_MA0849.1 7 bp overlap

FOXP1 1 dataset

Motif ES_0h ES_0h-FOXP1_MA0481.4 7 bp overlap

FOXP2 1 dataset

Motif ES_0h ES_0h-FOXP2_MA0593.2 9 bp overlap

FOXP3 1 dataset

Motif ES_0h ES_0h-FOXP3_MA0850.1 7 bp overlap

FOXP4 1 dataset

Motif ES_0h ES_0h-FOXP4_MA2117.1 7 bp overlap

FOXS1 1 dataset

Motif ES_0h ES_0h-FOXS1_MA2118.1 8 bp overlap

Foxf1 1 dataset

Motif ES_0h ES_0h-Foxf1_MA1606.2 7 bp overlap

Foxj2 1 dataset

Motif ES_0h ES_0h-Foxj2_MA0614.1 8 bp overlap

Foxj3 1 dataset

Motif ES_0h ES_0h-Foxj3_MA0851.2 9 bp overlap

Foxo1 1 dataset

Motif ES_0h ES_0h-Foxo1_MA0480.3 7 bp overlap

Foxo3 1 dataset

Motif ES_0h ES_0h-Foxo3_MA0157.4 7 bp overlap

GABPA 1 dataset

Motif ES_0h ES_0h-GABPA_MA0062.4 10 bp overlap

HIC2 1 dataset

Motif ES_0h ES_0h-HIC2_MA0738.2 6 bp overlap

Hand1::Tcf3 1 dataset

Motif ES_0h ES_0h-Hand1Tcf3_MA0092.2 9 bp overlap

IKZF1 1 dataset

Motif ES_0h ES_0h-IKZF1_MA1508.2 8 bp overlap

IKZF2 1 dataset

Motif ES_0h ES_0h-IKZF2_MA2326.1 6 bp overlap

IRF3 1 dataset

Motif ES_0h ES_0h-IRF3_MA1418.2 17 bp overlap

Ikzf3 1 dataset

Motif ES_0h ES_0h-Ikzf3_MA1992.2 9 bp overlap

Irf1 1 dataset

Motif ES_0h ES_0h-Irf1_MA0050.4 11 bp overlap

JUN 1 dataset

ChIP HUES-8 GSE109524.JUN.HUES-8 296 bp overlap

KLF1 2 datasets

Motif DE_12h DE_12h-KLF1_MA0493.3 8 bp overlap

Motif ES_0h ES_0h-KLF1_MA0493.3 8 bp overlap

KLF10 2 datasets

Motif DE_12h DE_12h-KLF10_MA1511.2 9 bp overlap

Motif ES_0h ES_0h-KLF10_MA1511.2 9 bp overlap

KLF11 2 datasets

Motif DE_12h DE_12h-KLF11_MA1512.2 10 bp overlap

Motif ES_0h ES_0h-KLF11_MA1512.2 10 bp overlap

KLF12 2 datasets

Motif DE_12h DE_12h-KLF12_MA0742.2 9 bp overlap

Motif ES_0h ES_0h-KLF12_MA0742.2 9 bp overlap

KLF14 2 datasets

Motif DE_12h DE_12h-KLF14_MA0740.2 9 bp overlap

Motif ES_0h ES_0h-KLF14_MA0740.2 9 bp overlap

KLF15 2 datasets

Motif DE_12h DE_12h-KLF15_MA1513.2 8 bp overlap

Motif ES_0h ES_0h-KLF15_MA1513.2 8 bp overlap

KLF16 2 datasets

Motif DE_12h DE_12h-KLF16_MA0741.1 11 bp overlap

Motif ES_0h ES_0h-KLF16_MA0741.1 11 bp overlap

KLF2 2 datasets

Motif DE_12h DE_12h-KLF2_MA1515.2 8 bp overlap

Motif ES_0h ES_0h-KLF2_MA1515.2 8 bp overlap

KLF4 2 datasets

Motif DE_12h DE_12h-KLF4_MA0039.5 8 bp overlap

Motif ES_0h ES_0h-KLF4_MA0039.5 8 bp overlap

KLF5 2 datasets

Motif DE_12h DE_12h-KLF5_MA0599.1 10 bp overlap

Motif ES_0h ES_0h-KLF5_MA0599.1 10 bp overlap

KLF7 2 datasets

Motif DE_12h DE_12h-KLF7_MA1959.2 8 bp overlap

Motif ES_0h ES_0h-KLF7_MA1959.2 8 bp overlap

MAZ 2 datasets

Motif DE_12h DE_12h-MAZ_MA1522.2 8 bp overlap

Motif ES_0h ES_0h-MAZ_MA1522.2 8 bp overlap

MEIS1 2 datasets

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

Motif ES_0h ES_0h-MEIS1_MA0498.3 5 bp overlap

MEIS2 2 datasets

Motif DE_12h DE_12h-MEIS2_MA0774.1 8 bp overlap

Motif ES_0h ES_0h-MEIS2_MA0774.1 8 bp overlap

MEIS3 2 datasets

Motif DE_12h DE_12h-MEIS3_MA0775.2 7 bp overlap

Motif ES_0h ES_0h-MEIS3_MA0775.2 7 bp overlap

NANOG 6 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 591 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 235 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 445 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 414 bp overlap

ChIP hESC GSE20650.NANOG.hESC 180 bp overlap

ChIP hESC GSE18292.NANOG.hESC 114 bp overlap

NFATC3 1 dataset

Motif ES_0h ES_0h-NFATC3_MA0625.3 6 bp overlap

NR1I2 1 dataset

Motif ES_0h ES_0h-NR1I2_MA1533.2 15 bp overlap

NR2C2 2 datasets

Motif DE_12h DE_12h-NR2C2_MA0504.2 14 bp overlap

Motif ES_0h ES_0h-NR2C2_MA0504.2 14 bp overlap

NR3C1 1 dataset

ChIP SUM159PT GSE152203.NR3C1.SUM159PT 222 bp overlap

Nfatc1 1 dataset

Motif ES_0h ES_0h-Nfatc1_MA0624.3 6 bp overlap

Nfatc2 1 dataset

Motif ES_0h ES_0h-Nfatc2_MA0152.3 8 bp overlap

Nr2F6 1 dataset

Motif ES_0h ES_0h-Nr2F6_MA0728.1 15 bp overlap

PATZ1 2 datasets

Motif DE_12h DE_12h-PATZ1_MA1961.2 11 bp overlap

Motif ES_0h ES_0h-PATZ1_MA1961.2 11 bp overlap

PCGF2 1 dataset

ChIP fibroblast_MET GSE55605.PCGF2.fibroblast_MET 226 bp overlap

POU5F1 1 dataset

ChIP HUES-8 GSE109524.POU5F1.HUES-8 591 bp overlap

PROX1 2 datasets

Motif DE_12h DE_12h-PROX1_MA0794.1 12 bp overlap

Motif ES_0h ES_0h-PROX1_MA0794.1 12 bp overlap

RARA 1 dataset

Motif ES_0h ES_0h-RARA_MA0729.1 18 bp overlap

RBPJ 1 dataset

Motif ES_0h ES_0h-RBPJ_MA1116.2 6 bp overlap

RNF2 1 dataset

ChIP fibroblast GSE139053.RNF2.fibroblast 178 bp overlap

RXRA::VDR 1 dataset

Motif ES_0h ES_0h-RXRAVDR_MA0074.1 15 bp overlap

Rarb 1 dataset

Motif ES_0h ES_0h-Rarb_MA0857.1 16 bp overlap

Rhox11 1 dataset

Motif ES_0h ES_0h-Rhox11_MA0629.2 9 bp overlap

SMARCA4 2 datasets

ChIP hiPSC GSE124903.SMARCA4.hiPSC 289 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 296 bp overlap

SMARCB1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 250 bp overlap

SMARCC1 2 datasets

ChIP ESC S25-ESC-d0-BAF155-exp1 238 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 233 bp overlap

SOX2 1 dataset

ChIP hiPSC GSE56567.SOX2.hiPSC 455 bp overlap

SP1 2 datasets

Motif DE_12h DE_12h-SP1_MA0079.5 9 bp overlap

Motif ES_0h ES_0h-SP1_MA0079.5 9 bp overlap

SP2 2 datasets

Motif DE_12h DE_12h-SP2_MA0516.3 9 bp overlap

Motif ES_0h ES_0h-SP2_MA0516.3 9 bp overlap

SP3 2 datasets

Motif DE_12h DE_12h-SP3_MA0746.3 11 bp overlap

Motif ES_0h ES_0h-SP3_MA0746.3 11 bp overlap

SP4 2 datasets

Motif DE_12h DE_12h-SP4_MA0685.2 9 bp overlap

Motif ES_0h ES_0h-SP4_MA0685.2 9 bp overlap

SP8 2 datasets

Motif DE_12h DE_12h-SP8_MA0747.2 11 bp overlap

Motif ES_0h ES_0h-SP8_MA0747.2 11 bp overlap

SP9 2 datasets

Motif DE_12h DE_12h-SP9_MA1564.2 10 bp overlap

Motif ES_0h ES_0h-SP9_MA1564.2 10 bp overlap

SPIC 1 dataset

Motif ES_0h ES_0h-SPIC_MA0687.2 13 bp overlap

STAT3 2 datasets

ChIP MCF-10A ENCSR000DOQ.STAT3.MCF-10A 239 bp overlap

ChIP MCF10A-Er-Src_TAM GSE115597.STAT3.MCF10A-Er-Src_TAM 199 bp overlap

SUZ12 2 datasets

ChIP CRL-7250_shSS18 GSE108025.SUZ12.CRL-7250_shSS18 499 bp overlap

ChIP hiPSC GSE124903.SUZ12.hiPSC 167 bp overlap

Stat2 1 dataset

Motif ES_0h ES_0h-Stat2_MA1623.2 10 bp overlap

THAP1 1 dataset

Motif ES_0h ES_0h-THAP1_MA0597.3 8 bp overlap

Vdr 1 dataset

Motif ES_0h ES_0h-Vdr_MA0693.4 7 bp overlap

ZBED4 2 datasets

Motif DE_12h DE_12h-ZBED4_MA2328.1 10 bp overlap

Motif ES_0h ES_0h-ZBED4_MA2328.1 10 bp overlap

ZBTB48 1 dataset

ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 256 bp overlap

ZBTB7B 1 dataset

Motif ES_0h ES_0h-ZBTB7B_MA0694.2 10 bp overlap

ZBTB7C 1 dataset

Motif ES_0h ES_0h-ZBTB7C_MA0695.2 8 bp overlap

ZNF121 1 dataset

ChIP WTC11 ENCFF291API 240 bp overlap

ZNF135 1 dataset

Motif DE_12h DE_12h-ZNF135_MA1587.1 14 bp overlap

ZNF148 2 datasets

Motif DE_12h DE_12h-ZNF148_MA1653.2 10 bp overlap

Motif ES_0h ES_0h-ZNF148_MA1653.2 10 bp overlap

ZNF175 1 dataset

Motif ES_0h ES_0h-ZNF175_MA2332.1 9 bp overlap

ZNF213 1 dataset

Motif DE_12h DE_12h-ZNF213_MA2121.1 12 bp overlap

ZNF214 2 datasets

Motif DE_12h DE_12h-ZNF214_MA1975.2 13 bp overlap

Motif ES_0h ES_0h-ZNF214_MA1975.2 13 bp overlap

ZNF341 2 datasets

Motif DE_12h DE_12h-ZNF341_MA1655.2 8 bp overlap

Motif ES_0h ES_0h-ZNF341_MA1655.2 8 bp overlap

ZNF460 1 dataset

Motif DE_12h DE_12h-ZNF460_MA1596.1 16 bp overlap

ZNF530 1 dataset

Motif ES_0h ES_0h-ZNF530_MA1981.2 14 bp overlap

ZNF558 1 dataset

Motif ES_0h ES_0h-ZNF558_MA2335.1 29 bp overlap

ZNF610 2 datasets

Motif DE_12h DE_12h-ZNF610_MA1713.2 10 bp overlap

Motif ES_0h ES_0h-ZNF610_MA1713.2 10 bp overlap

ZNF677 2 datasets

Motif DE_12h DE_12h-ZNF677_MA2101.1 12 bp overlap

Motif ES_0h ES_0h-ZNF677_MA2101.1 12 bp overlap

ZNF768 2 datasets

Motif DE_12h DE_12h-ZNF768_MA1731.2 9 bp overlap

Motif ES_0h ES_0h-ZNF768_MA1731.2 9 bp overlap