chr3:196,273,588–196,274,153

chr3 : 196,273,588 – 196,274,153

565 bp 95 TFs 8 linked genes

This 565 bp open chromatin element is linked to 8 target genes and is bound by 95 transcription factors.

Linked Genes

8 genes

Gene	Expression	Dist. to TSS	Distance	Link type
PCYT1A		13.9 kb	Distal	Multiome
DYNLT2B		44.5 kb	Distal	Multiome
UBXN7		158.6 kb	Distal	Multiome
TFRC		191.7 kb	Distal	Multiome
RNF168		229.9 kb	Distal	Multiome
SDHAP1		283.6 kb	Distal	Multiome
WDR53		294.7 kb	Distal	Multiome
FBXO45		294.8 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

95 transcription factors

AGO2 2 datasets

ChIP HepG2 ENCFF252VFI 404 bp overlap

ChIP HepG2 ENCFF252VFI 203 bp overlap

ChIP MDA-MB-453 ERP003503.AR.MDA-MB-453 135 bp overlap

ChIP MDA-MB-453_FOXA1 ERP003503.AR.MDA-MB-453_FOXA1 198 bp overlap

ChIP myofibroblast GSE90772.AR.myofibroblast 266 bp overlap

ASH2L 3 datasets

ChIP H1 ENCFF399KAM 462 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 192 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 169 bp overlap

BRD2 2 datasets

ChIP K-562_DMSO GSE138084.BRD2.K-562_DMSO 240 bp overlap

ChIP K-562_iBET-IFNG GSE138084.BRD2.K-562_iBET-IFNG 245 bp overlap

ChIP K-562_DMSO-IFNG GSE138084.BRD3.K-562_DMSO-IFNG 173 bp overlap

BRD4 6 datasets

ChIP CLL_patient1_4h_CpG GSE109411.BRD4.CLL_patient1_4h_CpG 248 bp overlap

ChIP CLL_patient2 GSE109411.BRD4.CLL_patient2 332 bp overlap

ChIP CLL_patient3_4h_CpG GSE109411.BRD4.CLL_patient3_4h_CpG 269 bp overlap

ChIP K-562_DMSO-IFNG GSE138084.BRD4.K-562_DMSO-IFNG 213 bp overlap

ChIP K-562_iBET-IFNG GSE138084.BRD4.K-562_iBET-IFNG 205 bp overlap

ChIP MCF-10A ERP003925.BRD4.MCF-10A 242 bp overlap

CBFA2T2 1 dataset

ChIP NCCIT GSE71675.CBFA2T2.NCCIT 284 bp overlap

ChIP K562 ENCFF410AQU 68 bp overlap

CHD1 2 datasets

ChIP hMSC-TERT GSE89179.CHD1.hMSC-TERT 253 bp overlap

ChIP hMSC-TERT_osteoblast GSE89179.CHD1.hMSC-TERT_osteoblast 325 bp overlap

CREB1 1 dataset

ChIP WA01 ENCSR000BSN.CREB1.WA01 175 bp overlap

CTCF 4 datasets

ChIP GSC23 GSE139416.CTCF.GSC23 105 bp overlap

ChIP T-47D_NaCl-isotonic GSE111923.CTCF.T-47D_NaCl-isotonic 450 bp overlap

ChIP T-47D_NaCl-isotonic-triptolide GSE111923.CTCF.T-47D_NaCl-isotonic-triptolide 188 bp overlap

ChIP T-47D_NaCl-triptolide GSE111923.CTCF.T-47D_NaCl-triptolide 458 bp overlap

Cebpa 4 datasets

ChIP BLaER1 ENCFF031ISE 126 bp overlap

ChIP BLaER1 ENCFF274GAT 85 bp overlap

ChIP BLaER1 ENCFF335XTP 213 bp overlap

ChIP BLaER1 ENCFF364PUR 230 bp overlap

DNMT3B 3 datasets

ChIP HUES-8 GSE99346.DNMT3B.HUES-8 67 bp overlap

ChIP HUES-8_TripleKO-TET1-2-3 GSE99346.DNMT3B.HUES-8_TripleKO-TET1-2-3 199 bp overlap

ChIP HUES-8_TripleKO-TET1-2-3 GSE99346.DNMT3B.HUES-8_TripleKO-TET1-2-3 211 bp overlap

ChIP LNCaP_shRB GSE94958.E2F1.LNCaP_shRB 161 bp overlap

Motif DE_24h DE_24h-EHF_MA0598.4 9 bp overlap

ELF1 5 datasets

Motif DE_24h DE_24h-ELF1_MA0473.4 9 bp overlap

ChIP GM12878 ENCSR000BMB.ELF1.GM12878 228 bp overlap

ChIP K-562 ENCSR502OEK.ELF1.K-562 289 bp overlap

ChIP K-562 ENCSR000BMD.ELF1.K-562 117 bp overlap

ChIP K562 ENCFF496AKI 277 bp overlap

Motif DE_24h DE_24h-ELF3_MA0640.3 9 bp overlap

Motif DE_24h DE_24h-ELK4_MA0076.3 9 bp overlap

ChIP SKNO-1 GSE23730.ERG.SKNO-1 300 bp overlap

ESR1 2 datasets

ChIP Ishikawa_siETV4-72h GSE129803.ESR1.Ishikawa_siETV4-72h 214 bp overlap

ChIP MCF-7_aldosterone GSE99626.ESR1.MCF-7_aldosterone 220 bp overlap

Motif DE_24h DE_24h-ETV1_MA0761.3 9 bp overlap

ETV6 2 datasets

Motif DE_24h DE_24h-ETV6_MA0645.2 9 bp overlap

Motif ES_0h ES_0h-ETV6_MA0645.2 9 bp overlap

ETV7 2 datasets

Motif DE_24h DE_24h-ETV7_MA1708.2 9 bp overlap

Motif ES_0h ES_0h-ETV7_MA1708.2 9 bp overlap

Motif DE_24h DE_24h-Elf5_MA0136.4 8 bp overlap

Motif DE_24h DE_24h-Erg_MA0474.4 10 bp overlap

FEZF2 3 datasets

Motif DE_24h DE_24h-FEZF2_MA2341.1 8 bp overlap

Motif ES_0h ES_0h-FEZF2_MA2341.1 8 bp overlap

Motif ES_0h ES_0h-FEZF2_MA2341.1 8 bp overlap

FOXA1 1 dataset

ChIP breast-cancer_heregulin GSE101407.FOXA1.breast-cancer_heregulin 228 bp overlap

GABPA 1 dataset

Motif DE_24h DE_24h-GABPA_MA0062.4 10 bp overlap

GATA2 1 dataset

ChIP ME-1_CBFB-MYH11-KD GSE117138.GATA2.ME-1_CBFB-MYH11-KD 97 bp overlap

ChIP K-562 ENCSR563YDA.HDGF.K-562 243 bp overlap

HIVEP1 2 datasets

ChIP Hep-G2 ENCSR697WMX.HIVEP1.Hep-G2 348 bp overlap

ChIP Hep-G2 ENCSR697WMX.HIVEP1.Hep-G2 119 bp overlap

IKZF2 1 dataset

Motif DE_24h DE_24h-IKZF2_MA2326.1 6 bp overlap

Ikzf3 1 dataset

Motif DE_24h DE_24h-Ikzf3_MA1992.2 9 bp overlap

ChIP Karpas-299 GSE151413.JUN.Karpas-299 339 bp overlap

ChIP Karpas-299 GSE151413.JUNB.Karpas-299 225 bp overlap

KDM4A 1 dataset

ChIP H1 ENCFF078LED 121 bp overlap

KDM4C 1 dataset

ChIP KYSE-150 GSE53938.KDM4C.KYSE-150 244 bp overlap

KLF13 1 dataset

Motif ES_0h ES_0h-KLF13_MA0657.2 17 bp overlap

KLF15 1 dataset

Motif ES_0h ES_0h-KLF15_MA1513.2 8 bp overlap

KLF16 1 dataset

Motif ES_0h ES_0h-KLF16_MA0741.1 11 bp overlap

ChIP HEK293 ENCSR076EZB.KLF9.HEK293 427 bp overlap

ChIP H1 ENCFF914VQY 357 bp overlap

ChIP 501-mel_K243Q GSE137522.MITF.501-mel_K243Q 65 bp overlap

MYOD1 1 dataset

ChIP IMR-90_GM GSE128527.MYOD1.IMR-90_GM 96 bp overlap

NFKB1 1 dataset

Motif ES_0h ES_0h-NFKB1_MA0105.4 13 bp overlap

NFKB2 1 dataset

Motif ES_0h ES_0h-NFKB2_MA0778.2 11 bp overlap

NFYA 2 datasets

Motif DE_24h DE_24h-NFYA_MA0060.4 8 bp overlap

ChIP K562 ENCFF732HOX 374 bp overlap

Motif DE_24h DE_24h-NFYB_MA0502.3 9 bp overlap

Motif DE_24h DE_24h-NFYC_MA1644.2 7 bp overlap

Motif DE_24h DE_24h-PBX1_MA0070.2 9 bp overlap

POLR2A 2 datasets

ChIP H1 ENCFF566JSR 353 bp overlap

ChIP H1 ENCFF833NJP 315 bp overlap

POLR2G 2 datasets

ChIP K562 ENCFF047BLG 187 bp overlap

ChIP K562 ENCFF648YPL 190 bp overlap

POU5F1 2 datasets

ChIP BG03 GSE21614.POU5F1.BG03 298 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 357 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 342 bp overlap

RBFOX2 4 datasets

ChIP K-562 ENCSR822LBD.RBFOX2.K-562 336 bp overlap

ChIP K-562 GSE120104.RBFOX2.K-562 334 bp overlap

ChIP K562 ENCFF196WTG 161 bp overlap

ChIP K562 ENCFF967GRF 305 bp overlap

RBM39 2 datasets

ChIP Hep-G2 ENCSR339JTP.RBM39.Hep-G2 260 bp overlap

ChIP Hep-G2 GSE120104.RBM39.Hep-G2 260 bp overlap

ChIP HEK293_TNF-1h GSE75562.RELA.HEK293_TNF-1h 74 bp overlap

SETDB1 2 datasets

ChIP HEK293 ENCSR348AGV.SETDB1.HEK293 136 bp overlap

ChIP U2OS ENCSR000EYD.SETDB1.U2OS 136 bp overlap

SIN3A 2 datasets

ChIP H1 ENCFF042ZSL 507 bp overlap

ChIP WA01 ENCSR000EBO.SIN3A.WA01 176 bp overlap

SMAD3 1 dataset

ChIP BG03 GSE21614.SMAD3.BG03 142 bp overlap

ChIP H1 ENCFF263FUH 321 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 268 bp overlap

Motif ES_0h ES_0h-SP3_MA0746.3 11 bp overlap

Motif ES_0h ES_0h-SP8_MA0747.2 11 bp overlap

Motif DE_24h DE_24h-SPIB_MA0081.3 13 bp overlap

TAF1 2 datasets

ChIP H1 ENCFF478SZO 385 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 233 bp overlap

ChIP H1 ENCFF859IIO 306 bp overlap

ChIP WA01 ENCSR000ECB.TBP.WA01 208 bp overlap

TEAD1 2 datasets

Motif DE_24h DE_24h-TEAD1_MA0090.4 9 bp overlap

Motif ES_0h ES_0h-TEAD1_MA0090.4 9 bp overlap

TEAD4 3 datasets

Motif DE_24h DE_24h-TEAD4_MA0809.3 8 bp overlap

Motif ES_0h ES_0h-TEAD4_MA0809.3 8 bp overlap

ChIP H1 ENCFF778PAX 245 bp overlap

TFAP2A 1 dataset

Motif ES_0h ES_0h-TFAP2A_MA0003.5 9 bp overlap

TFAP2B 1 dataset

Motif ES_0h ES_0h-TFAP2B_MA0812.2 9 bp overlap

TFAP2C 1 dataset

Motif ES_0h ES_0h-TFAP2C_MA0814.3 9 bp overlap

TFAP2E 1 dataset

Motif ES_0h ES_0h-TFAP2E_MA1569.2 9 bp overlap

TP63 2 datasets

ChIP keratinocyte GSE33571.TP63.keratinocyte 134 bp overlap

ChIP keratinocyte_diff GSE33571.TP63.keratinocyte_diff 165 bp overlap

TRIM24 1 dataset

ChIP K-562 ENCSR907MZR.TRIM24.K-562 100 bp overlap

TRIM28 2 datasets

ChIP K-562 ENCSR474CVP.TRIM28.K-562 158 bp overlap

ChIP WIBR3_NAIVE GSE84382.TRIM28.WIBR3_NAIVE 226 bp overlap

ChIP H1 ENCFF524BTL 312 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 184 bp overlap

ZBTB11 1 dataset

Motif DE_24h DE_24h-ZBTB11_MA2329.1 9 bp overlap

ZBTB33 4 datasets

ChIP HepG2 ENCFF778UKV 97 bp overlap

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 565 bp overlap

ChIP K562 ENCFF427SDV 279 bp overlap

ChIP K562 ENCFF875HLX 431 bp overlap

ZBTB48 1 dataset

ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 97 bp overlap

ZBTB7A 2 datasets

Motif DE_24h DE_24h-ZBTB7A_MA0750.3 9 bp overlap

ChIP K-562 ENCSR000BME.ZBTB7A.K-562 91 bp overlap

ZNF143 1 dataset

ChIP MCF-7 GSE76454.ZNF143.MCF-7 157 bp overlap

ZNF175 1 dataset

Motif DE_24h DE_24h-ZNF175_MA2332.1 9 bp overlap

ZNF213 2 datasets

Motif DE_24h DE_24h-ZNF213_MA2121.1 12 bp overlap

Motif ES_0h ES_0h-ZNF213_MA2121.1 12 bp overlap

ZNF263 1 dataset

ChIP K-562 ENCSR000EWN.ZNF263.K-562 187 bp overlap

ZNF274 2 datasets

Motif DE_24h DE_24h-ZNF274_MA1592.2 12 bp overlap

Motif ES_0h ES_0h-ZNF274_MA1592.2 12 bp overlap

ChIP K562 ENCFF540WBG 118 bp overlap

ZNF324 1 dataset

Motif ES_0h ES_0h-ZNF324_MA1977.2 14 bp overlap

ZNF343 1 dataset

Motif ES_0h ES_0h-ZNF343_MA1711.2 16 bp overlap

ZNF449 1 dataset

Motif ES_0h ES_0h-ZNF449_MA1656.2 10 bp overlap

ZNF550 1 dataset

ChIP Hep-G2 ENCSR198BHH.ZNF550.Hep-G2 224 bp overlap

ZNF572 1 dataset

ChIP Hep-G2 ENCSR663CTC.ZNF572.Hep-G2 159 bp overlap

ZNF680 2 datasets

ChIP HEK293 ENCFF418WHE 54 bp overlap

ChIP HEK293 ENCSR307CKC.ZNF680.HEK293 141 bp overlap

ZNF682 1 dataset

Motif ES_0h ES_0h-ZNF682_MA1599.2 11 bp overlap

ZNF692 1 dataset

Motif ES_0h ES_0h-ZNF692_MA1986.2 8 bp overlap

ZNF768 1 dataset

ChIP HepG2 ENCFF388QCK 315 bp overlap