chr2:61,165,843–61,166,373

chr2 : 61,165,843 – 61,166,373

530 bp 88 TFs 6 linked genes

This 530 bp open chromatin element is linked to 6 target genes and is bound by 88 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
C2orf74		21.1 kb	Distal	Multiome
C2orf74-DT		21.2 kb	Distal	Multiome
SANBR		100.3 kb	Distal	Multiome
PUS10		147.9 kb	Distal	Multiome
PEX13		148.4 kb	Distal	Multiome
REL		284.6 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

88 transcription factors

ChIP HCT-116 GSE103894.APC.HCT-116 265 bp overlap

ARID1B 2 datasets

ChIP K-562 ENCSR822CCM.ARID1B.K-562 341 bp overlap

ChIP K562 ENCFF938UXQ 248 bp overlap

ATF1 2 datasets

ChIP K-562 ENCSR000DNZ.ATF1.K-562 124 bp overlap

ChIP K562 ENCFF980NSF 251 bp overlap

ChIP Hep-G2 ENCSR402ZCY.ATF3.Hep-G2 184 bp overlap

ChIP K-562 ENCSR808AKZ.BCOR.K-562 222 bp overlap

ChIP K-562_DMSO GSE138084.BRD3.K-562_DMSO 345 bp overlap

BRD4 5 datasets

ChIP IMR-90_QUIES GSE74238.BRD4.IMR-90_QUIES 119 bp overlap

ChIP K-562_iBET GSE138084.BRD4.K-562_iBET 280 bp overlap

ChIP K-562_iBET-BD1-IFNG GSE138084.BRD4.K-562_iBET-BD1-IFNG 240 bp overlap

ChIP K-562_iBET-BD2-IFNG GSE138084.BRD4.K-562_iBET-BD2-IFNG 236 bp overlap

ChIP K-562_iBET-IFNG GSE138084.BRD4.K-562_iBET-IFNG 275 bp overlap

CBFA2T3 2 datasets

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 323 bp overlap

ChIP K562 ENCFF673OEZ 194 bp overlap

CC2D1A 1 dataset

ChIP K-562 ENCSR343IFJ.CC2D1A.K-562 278 bp overlap

ChIP MM1-S_JQ1_500NM GSE42355.CDK9.MM1-S_JQ1_500NM 167 bp overlap

CEBPA 2 datasets

ChIP Kasumi-1_CEBPA-ER GSE102697.CEBPA.Kasumi-1_CEBPA-ER 197 bp overlap

ChIP Kasumi-1_CEBPA-ER_E2 GSE102697.CEBPA.Kasumi-1_CEBPA-ER_E2 171 bp overlap

CEBPB 3 datasets

ChIP K-562 ENCSR000BRQ.CEBPB.K-562 256 bp overlap

ChIP K562 ENCFF194QGF 321 bp overlap

ChIP K562 ENCFF584CTB 473 bp overlap

CEBPD 1 dataset

ChIP K-562 ENCSR000BVY.CEBPD.K-562 108 bp overlap

CREM 2 datasets

ChIP K-562 ENCSR077DKV.CREM.K-562 209 bp overlap

ChIP K562 ENCFF180STA 296 bp overlap

CTCF 71 datasets

ChIP A-549 ENCSR000AUE.CTCF.A-549 243 bp overlap

ChIP Caco-2 ENCSR000DQN.CTCF.Caco-2 129 bp overlap

Motif DE_36h DE_36h-CTCF_MA0139.2 15 bp overlap

ChIP GM23338 ENCFF772DML 201 bp overlap

ChIP HAP1 GSE152721.CTCF.HAP1 254 bp overlap

ChIP HAP1_2kb GSE152721.CTCF.HAP1_2kb 178 bp overlap

ChIP HAP1_clone21_TSS-CRISPR GSE152721.CTCF.HAP1_clone21_TSS-CRISPR 229 bp overlap

ChIP HCT-116 ENCSR240PRQ.CTCF.HCT-116 282 bp overlap

ChIP HCT-116 GSE131606.CTCF.HCT-116 254 bp overlap

ChIP HCT-116 ENCSR000BSE.CTCF.HCT-116 148 bp overlap

ChIP HeLa GSE126990.CTCF.HeLa 207 bp overlap

ChIP HeLa-Kyoto GSE138405.CTCF.HeLa-Kyoto 207 bp overlap

ChIP HeLa-Kyoto_PDS5-depleted GSE102884.CTCF.HeLa-Kyoto_PDS5-depleted 256 bp overlap

ChIP HeLa-S3 ENCFF565UFR 161 bp overlap

ChIP HeLa-S3 ENCSR000AOA.CTCF.HeLa-S3 221 bp overlap

ChIP HeLa-S3 ENCSR000DLO.CTCF.HeLa-S3 92 bp overlap

ChIP IMR-90 ENCSR000EFI.CTCF.IMR-90 150 bp overlap

ChIP K-562 ENCSR000AKO.CTCF.K-562 326 bp overlap

ChIP K-562 GSE92879.CTCF.K-562 220 bp overlap

ChIP K-562 GSE70764.CTCF.K-562 216 bp overlap

ChIP K-562 ENCSR000EGM.CTCF.K-562 178 bp overlap

ChIP K-562 ENCSR000DWE.CTCF.K-562 168 bp overlap

ChIP K-562 ENCSR000DMA.CTCF.K-562 127 bp overlap

ChIP K-562 GSE110681.CTCF.K-562 170 bp overlap

ChIP K-562 GSE70482.CTCF.K-562 153 bp overlap

ChIP K-562_11698 GSE131349.CTCF.K-562_11698 118 bp overlap

ChIP K-562_12040 GSE131349.CTCF.K-562_12040 97 bp overlap

ChIP K-562_13189 GSE131349.CTCF.K-562_13189 135 bp overlap

ChIP K-562_14259 GSE131349.CTCF.K-562_14259 155 bp overlap

ChIP K-562_14376 GSE131349.CTCF.K-562_14376 97 bp overlap

ChIP K-562_15173 GSE131349.CTCF.K-562_15173 134 bp overlap

ChIP K-562_15776 GSE131349.CTCF.K-562_15776 98 bp overlap

ChIP K-562_5635 GSE131349.CTCF.K-562_5635 146 bp overlap

ChIP K-562_7140 GSE131349.CTCF.K-562_7140 155 bp overlap

ChIP K-562_8004 GSE131349.CTCF.K-562_8004 103 bp overlap

ChIP K-562_MonoC GSE137216.CTCF.K-562_MonoC 408 bp overlap

ChIP K-562_MonoN GSE137216.CTCF.K-562_MonoN 207 bp overlap

ChIP K-562_RF2-insertion GSE140868.CTCF.K-562_RF2-insertion 201 bp overlap

ChIP K-562_RF2-mutation GSE140868.CTCF.K-562_RF2-mutation 183 bp overlap

ChIP K-562_RabbitC GSE137216.CTCF.K-562_RabbitC 329 bp overlap

ChIP K-562_WT GSE140868.CTCF.K-562_WT 185 bp overlap

ChIP K-562_dCas9-KRAB GSE132212.CTCF.K-562_dCas9-KRAB 282 bp overlap

ChIP K-562_enCRISPRi-KL GSE132212.CTCF.K-562_enCRISPRi-KL 363 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.CTCF.K-562_enCRISPRi-LK 328 bp overlap

ChIP K562 ENCFF082GOI 185 bp overlap

ChIP K562 ENCFF400DFR 241 bp overlap

ChIP K562 ENCFF430KTH 425 bp overlap

ChIP MCF-7 ENCFF198DQX 231 bp overlap

ChIP MCF-7 ENCFF414SZG 191 bp overlap

ChIP MCF-7 ENCFF424NQR 191 bp overlap

ChIP MCF-7 ENCFF494VXA 231 bp overlap

ChIP MCF-7 ENCFF844STM 191 bp overlap

ChIP MCF-7 ENCFF954TUV 205 bp overlap

ChIP MCF-7 ENCSR560BUE.CTCF.MCF-7 190 bp overlap

ChIP OCI-LY7 ENCFF086AXQ 495 bp overlap

ChIP OVCAR-8 GSE70764.CTCF.OVCAR-8 149 bp overlap

ChIP RH4 GSE83726.CTCF.RH4 181 bp overlap

ChIP THP-1_Pam3csk-020m-Flavo-000m GSE103477.CTCF.THP-1_Pam3csk-020m-Flavo-000m 207 bp overlap

ChIP THP-1_Pam3csk-025m-Flavo-000m GSE103477.CTCF.THP-1_Pam3csk-025m-Flavo-000m 216 bp overlap

ChIP THP-1_Pam3csk-150m-Flavo-030m GSE103477.CTCF.THP-1_Pam3csk-150m-Flavo-030m 162 bp overlap

ChIP THP-1_macrophage_PMA GSE96800.CTCF.THP-1_macrophage_PMA 238 bp overlap

ChIP endodermal cell ENCFF471YCZ 185 bp overlap

ChIP endothelial_brain-microvascular ENCSR000DTA.CTCF.endothelial_brain-microvascular 131 bp overlap

ChIP fibroblast of villous mesenchyme ENCFF345VQO 321 bp overlap

ChIP fibroblast_VILLOUS_MESENCHYME ENCSR000DVQ.CTCF.fibroblast_VILLOUS_MESENCHYME 210 bp overlap

ChIP hESC_NAIVE GSE69646.CTCF.hESC_NAIVE 257 bp overlap

ChIP keratinocyte ENCSR000DNC.CTCF.keratinocyte 118 bp overlap

ChIP myoblast_skeletal_muscle ENCSR000ANE.CTCF.myoblast_skeletal_muscle 242 bp overlap

ChIP myotube ENCFF981UHL 108 bp overlap

ChIP myotube ENCSR000ANS.CTCF.myotube 347 bp overlap

ChIP skeletal muscle myoblast ENCFF813BQI 291 bp overlap

DACH1 1 dataset

ChIP K562 ENCFF574LOW 381 bp overlap

ChIP K562 ENCFF775HUO 433 bp overlap

EGR1 4 datasets

ChIP K-562 ENCSR000BNE.EGR1.K-562 178 bp overlap

ChIP K562 ENCFF006PJY 245 bp overlap

ChIP macrophage_D1 GSE136216.EGR1.macrophage_D1 190 bp overlap

ChIP macrophage_D3 GSE136216.EGR1.macrophage_D3 247 bp overlap

EHMT2 2 datasets

ChIP K-562 ENCSR175EOM.EHMT2.K-562 323 bp overlap

ChIP K562 ENCFF053BWO 183 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 291 bp overlap

EP300 2 datasets

ChIP AML GSE131939.EP300.AML 110 bp overlap

ChIP AML_shaml1-eto GSE131939.EP300.AML_shaml1-eto 129 bp overlap

ChIP breast_tumor_BADOUTCOME GSE40867.ESR1.breast_tumor_BADOUTCOME 218 bp overlap

ChIP SKH1 GSE87283.EVI1.SKH1 168 bp overlap

ChIP K-562 ENCSR000DKB.FOS.K-562 131 bp overlap

FOSL1 2 datasets

ChIP K-562 ENCSR239ZLZ.FOSL1.K-562 213 bp overlap

ChIP K562 ENCFF455MKD 530 bp overlap

GATA1 3 datasets

ChIP K-562 GSE107726.GATA1.K-562 212 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 227 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 268 bp overlap

GATA2 9 datasets

ChIP ESF GSE108408.GATA2.ESF 240 bp overlap

ChIP K-562 ENCSR000DKA.GATA2.K-562 481 bp overlap

ChIP K-562 ENCSR000EWG.GATA2.K-562 139 bp overlap

ChIP K-562 ENCSR257RKC.GATA2.K-562 170 bp overlap

ChIP K562 ENCFF513FTZ 301 bp overlap

ChIP K562 ENCFF830LLA 530 bp overlap

ChIP SKH1 GSE87283.GATA2.SKH1 212 bp overlap

ChIP TF1 GSE73207.GATA2.TF1 245 bp overlap

ChIP dermal-fibroblast_alone GSE51025.GATA2.dermal-fibroblast_alone 230 bp overlap

GATA4 4 datasets

ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.GATA4.BJ1-hTERT_FOXA2_GATA4_Coexp 177 bp overlap

ChIP DE DE-GATA4-1 478 bp overlap

ChIP DE DE-GATA4-2 477 bp overlap

ChIP foregut GSE117136.GATA4.foregut 284 bp overlap

GATA6 10 datasets

ChIP AGS GSE51936.GATA6.AGS 63 bp overlap

ChIP DE DE-GATA6-1 437 bp overlap

ChIP DE DE-GATA6-2 503 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 485 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 477 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 507 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 421 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 502 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 507 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 490 bp overlap

GFI1B 1 dataset

ChIP K-562 ENCSR509GDT.GFI1B.K-562 112 bp overlap

HDAC1 2 datasets

ChIP K-562 ENCSR387UWP.HDAC1.K-562 246 bp overlap

ChIP K-562_dilution-6-100 GSE140325.HDAC1.K-562_dilution-6-100 72 bp overlap

HDAC2 1 dataset

ChIP K-562 GSE140325.HDAC2.K-562 92 bp overlap

HMBOX1 3 datasets

ChIP K-562 ENCSR757IIU.HMBOX1.K-562 295 bp overlap

ChIP K562 ENCFF055GAZ 472 bp overlap

ChIP K562 ENCFF317JJX 482 bp overlap

HNRNPUL1 2 datasets

ChIP K-562 ENCSR296MXW.HNRNPUL1.K-562 370 bp overlap

ChIP K-562 GSE120104.HNRNPUL1.K-562 342 bp overlap

IKZF1 3 datasets

ChIP K-562 ENCSR395HWC.IKZF1.K-562 358 bp overlap

ChIP K562 ENCFF348IBL 253 bp overlap

ChIP K562 ENCFF771OHZ 299 bp overlap

ChIP K-562 GSE103215.ILF3.K-562 378 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 440 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 525 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 310 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 528 bp overlap

ChIP K-562 ENCSR000DJY.JUNB.K-562 201 bp overlap

JUND 2 datasets

ChIP K-562 ENCSR000EGN.JUND.K-562 192 bp overlap

ChIP K562 ENCFF336RCR 461 bp overlap

KLF16 1 dataset

ChIP K-562 ENCSR760UVO.KLF16.K-562 183 bp overlap

KMT2A 1 dataset

ChIP Hep-G2 ENCSR692GFR.KMT2A.Hep-G2 121 bp overlap

LDB1 2 datasets

ChIP Kasumi-1_ctrl GSE121280.LDB1.Kasumi-1_ctrl 232 bp overlap

ChIP Kasumi-1_siRE GSE121280.LDB1.Kasumi-1_siRE 227 bp overlap

ChIP Kasumi-1_SICTR GSE60130.LMO2.Kasumi-1_SICTR 166 bp overlap

ChIP K-562 ENCSR000EFX.MAZ.K-562 100 bp overlap

MED26 1 dataset

ChIP HEK293T GSE121024.MED26.HEK293T 288 bp overlap

NCOA1 1 dataset

ChIP MCF-7_E2 ERP000901.NCOA1.MCF-7_E2 119 bp overlap

NFE2L2 1 dataset

ChIP K-562 ENCSR485GKE.NFE2L2.K-562 221 bp overlap

NR3C1 1 dataset

ChIP A-549 ENCSR000BHF.NR3C1.A-549 129 bp overlap

POLR2A 1 dataset

ChIP spleen ENCFF044PYR 437 bp overlap

PRDM10 2 datasets

ChIP K-562 ENCSR120MPG.PRDM10.K-562 253 bp overlap

ChIP K562 ENCFF740YLK 417 bp overlap

RAD21 8 datasets

ChIP HCT-116 GSE121355.RAD21.HCT-116 354 bp overlap

ChIP HCT-116 GSE131606.RAD21.HCT-116 228 bp overlap

ChIP HCT-116 ENCSR000BSB.RAD21.HCT-116 164 bp overlap

ChIP HCT116 ENCFF568PEO 311 bp overlap

ChIP K-562 ENCSR000BKV.RAD21.K-562 99 bp overlap

ChIP K-562_RF2-insertion GSE140868.RAD21.K-562_RF2-insertion 208 bp overlap

ChIP K562 ENCFF634XYR 365 bp overlap

ChIP MCF-7 GSE72082.RAD21.MCF-7 222 bp overlap

RCOR1 1 dataset

ChIP K562 ENCFF216EEJ 297 bp overlap

ChIP K-562 ENCSR000BMW.REST.K-562 104 bp overlap

RUNX1 2 datasets

ChIP Kasumi-1 GSE65427.RUNX1.Kasumi-1 200 bp overlap

ChIP SKNO-1 GSE23730.RUNX1.SKNO-1 211 bp overlap

RUNX1-RUNX1T1 1 dataset

ChIP AML GSE131939.RUNX1-RUNX1T1.AML 216 bp overlap

RUNX1T1 2 datasets

ChIP Kasumi-1 GSE115115.RUNX1T1.Kasumi-1 305 bp overlap

ChIP Kasumi-1 GSE65427.RUNX1T1.Kasumi-1 155 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 273 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 508 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 528 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 530 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 530 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 473 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 478 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 483 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 482 bp overlap

SMAD3 2 datasets

ChIP BG03_DIFF_48H GSE36578.SMAD3.BG03_DIFF_48H 259 bp overlap

ChIP endoderm GSE29422.SMAD3.endoderm 222 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 279 bp overlap

SMARCA4 2 datasets

ChIP K-562 ENCSR587OQL.SMARCA4.K-562 291 bp overlap

ChIP K562 ENCFF506JCB 404 bp overlap

SMARCC1 1 dataset

ChIP DE_D1 S10-DE-d1-BAF155-exp1 358 bp overlap

SMARCE1 2 datasets

ChIP K-562 ENCSR157TCS.SMARCE1.K-562 382 bp overlap

ChIP K562 ENCFF690CFF 515 bp overlap

SNAI2 2 datasets

ChIP SMS-CTR_D48 GSE137168.SNAI2.SMS-CTR_D48 266 bp overlap

ChIP SMS-CTR_T48 GSE137168.SNAI2.SMS-CTR_T48 218 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 270 bp overlap

Motif DE_36h DE_36h-SP5_MA1965.2 6 bp overlap

STAG1 2 datasets

ChIP HeLa GSE126990.STAG1.HeLa 285 bp overlap

ChIP HeLa-Kyoto GSE138405.STAG1.HeLa-Kyoto 285 bp overlap

STAT5A 1 dataset

ChIP K562 ENCFF226BTJ 341 bp overlap

Motif DE_36h DE_36h-Six3_MA0631.2 11 bp overlap

TAL1 3 datasets

ChIP K-562 GSE107726.TAL1.K-562 247 bp overlap

ChIP K-562_dCas9-KRAB GSE132212.TAL1.K-562_dCas9-KRAB 158 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 209 bp overlap

ChIP K-562 GSE55306.TBP.K-562 203 bp overlap

TCF12 3 datasets

ChIP K-562 ENCSR744WOO.TCF12.K-562 197 bp overlap

ChIP K562 ENCFF931DJY 391 bp overlap

ChIP Kasumi-1 GSE23730.TCF12.Kasumi-1 178 bp overlap

TCF3 2 datasets

ChIP K-562 ENCSR970OJY.TCF3.K-562 176 bp overlap

ChIP Kasumi-1 GSE43834.TCF3.Kasumi-1 410 bp overlap

TEAD1 1 dataset

ChIP K-562 ENCSR591ASD.TEAD1.K-562 201 bp overlap

TEAD2 1 dataset

ChIP K562 ENCFF039ZWC 271 bp overlap

TEAD4 1 dataset

ChIP K562 ENCFF673NIK 173 bp overlap

TFAP4 1 dataset

ChIP K562 ENCFF727PXG 499 bp overlap

TRIM24 2 datasets

ChIP K-562 ENCSR907MZR.TRIM24.K-562 296 bp overlap

ChIP K562 ENCFF616RIL 451 bp overlap

ZBTB7A 1 dataset

ChIP K-562 GSE103445.ZBTB7A.K-562 194 bp overlap

ZC3H8 1 dataset

ChIP HCT-116 GSE47938.ZC3H8.HCT-116 283 bp overlap

ChIP K562 ENCFF975RXS 436 bp overlap

Motif DE_36h DE_36h-ZIC1_MA0696.1 14 bp overlap

Motif DE_36h DE_36h-ZIC5_MA1584.2 15 bp overlap

ZKSCAN1 1 dataset

ChIP K-562 ENCSR882ERE.ZKSCAN1.K-562 121 bp overlap

ZNF143 1 dataset

ChIP K-562 GSE39263.ZNF143.K-562 179 bp overlap

ZNF18 1 dataset

ChIP K-562 GSE97661.ZNF18.K-562 266 bp overlap

ZNF24 4 datasets

ChIP K-562 ENCSR695EQB.ZNF24.K-562 347 bp overlap

ChIP K-562 ENCSR099NCH.ZNF24.K-562 267 bp overlap

ChIP K562 ENCFF615YYW 394 bp overlap

ChIP K562 ENCFF877JCX 419 bp overlap