chr16 : 68,019,222 – 68,020,043
821 bp 108 TFs 17 linked genes
This 821 bp open chromatin element is linked to 17 target genes and is bound by 108 transcription factors.
Linked Genes
17 genes
Distance
Link type
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
DDX28 3.2 kb Proximal Proximity
DUS2 3.2 kb Proximal Proximity
DPEP3 38.9 kb Distal Multiome
SLC12A4 50.8 kb Distal Multiome
NFATC3 65.9 kb Distal Multiome
PSKH1 126.2 kb Distal Multiome
EDC4 146.4 kb Distal Multiome
NUTF2 172.5 kb Distal Multiome
THAP11 177.1 kb Distal Multiome
CENPT 185.6 kb Distal Multiome
RANBP10 212.9 kb Distal Multiome
ESRP2 216.7 kb Distal Multiome
PLA2G15 225.9 kb Distal Multiome
SLC7A6 245.1 kb Distal Multiome
SLC7A6OS 291.5 kb Distal Multiome
PRMT7 291.6 kb Distal Multiome
GFOD2 300.1 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr16:68,014,222 – 68,025,043
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
108 transcription factors
Source
Cell type
AGO1 3 datasets
ChIP K-562 GSE120104.AGO1.K-562 229 bp overlap
ChIP K-562 ENCSR641BSL.AGO1.K-562 157 bp overlap
ChIP K562 ENCFF025NLP 717 bp overlap
Ahr::Arnt 2 datasets
Motif DE_48h DE_48h-AhrArnt_MA0006.2 5 bp overlap
Motif DE_72h DE_72h-AhrArnt_MA0006.2 5 bp overlap
BRD4 2 datasets
ChIP CD4_JG1 GSE33281.BRD4.CD4_JG1 103 bp overlap
ChIP MV4-11_SGC GSE71776.BRD4.MV4-11_SGC 379 bp overlap
CBFA2T2 1 dataset
ChIP K562 ENCFF963TXY 296 bp overlap
CBFA2T3 2 datasets
ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 322 bp overlap
ChIP K562 ENCFF673OEZ 210 bp overlap
CTCF 2 datasets
Motif DE_72h DE_72h-CTCF_MA1930.2 33 bp overlap
ChIP HeLa-S3 ENCSR000AOA.CTCF.HeLa-S3 202 bp overlap
Cebpa 2 datasets
ChIP BLaER1 ENCFF335XTP 354 bp overlap
ChIP BLaER1 ENCFF364PUR 381 bp overlap
Crx 1 dataset
Motif DE_72h DE_72h-Crx_MA0467.3 6 bp overlap
EOMES 3 datasets
Motif DE_72h DE_72h-EOMES_MA0800.2 9 bp overlap
ChIP hESC GSE26097.EOMES.hESC 292 bp overlap
ChIP hESC GSE26097.EOMES.hESC 227 bp overlap
ESR1 9 datasets
ChIP MCF-7_DMSO GSE125594.ESR1.MCF-7_DMSO 215 bp overlap
ChIP MCF-7_E2-40min-ERalpha GSE94023.ESR1.MCF-7_E2-40min-ERalpha 231 bp overlap
ChIP MCF-7_SHCRT_E2 ERP000380.ESR1.MCF-7_SHCRT_E2 109 bp overlap
ChIP MCF-7_estradiol-DHT_4h GSE99626.ESR1.MCF-7_estradiol-DHT_4h 180 bp overlap
ChIP U2OS_100nM-E2 GSE151039.ESR1.U2OS_100nM-E2 516 bp overlap
ChIP U2OS_10nM-E2 GSE151039.ESR1.U2OS_10nM-E2 458 bp overlap
ChIP U2OS_10nM-E2-B GSE151039.ESR1.U2OS_10nM-E2-B 436 bp overlap
ChIP U2OS_E2 GSE26110.ESR1.U2OS_E2 163 bp overlap
ChIP VCaP_E2_ERA GSE43985.ESR1.VCaP_E2_ERA 179 bp overlap
Esrrg 2 datasets
Motif DE_48h DE_48h-Esrrg_MA0643.2 9 bp overlap
Motif DE_72h DE_72h-Esrrg_MA0643.2 9 bp overlap
FIGLA 1 dataset
Motif DE_72h DE_72h-FIGLA_MA0820.2 6 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 821 bp overlap
ChIP DE DE-FOXA2-2 704 bp overlap
GATA1 2 datasets
ChIP CD34_Day7_30min GSE104676.GATA1.CD34_Day7_30min 63 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 161 bp overlap
GATA4 5 datasets
ChIP DE DE-GATA4-1 821 bp overlap
ChIP DE DE-GATA4-2 821 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 501 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 234 bp overlap
GATA5 1 dataset
Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap
GATA6 12 datasets
ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 102 bp overlap
ChIP DE DE-GATA6-1 821 bp overlap
ChIP DE DE-GATA6-2 821 bp overlap
Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 821 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 508 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 413 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 821 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 813 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 821 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 510 bp overlap
ChIP foregut GSE117136.GATA6.foregut 474 bp overlap
GLIS1 1 dataset
ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 162 bp overlap
GSC 1 dataset
Motif DE_72h DE_72h-GSC_MA0648.2 6 bp overlap
GSC2 1 dataset
Motif DE_72h DE_72h-GSC2_MA0891.2 6 bp overlap
Gata3 1 dataset
Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap
HDAC2 2 datasets
ChIP K-562 ENCSR893WSB.HDAC2.K-562 306 bp overlap
ChIP K562 ENCFF744ALD 195 bp overlap
HOXA3 2 datasets
Motif DE_48h DE_48h-HOXA3_MA2119.1 7 bp overlap
Motif DE_72h DE_72h-HOXA3_MA2119.1 7 bp overlap
HOXA4 2 datasets
Motif DE_48h DE_48h-HOXA4_MA1496.2 7 bp overlap
Motif DE_72h DE_72h-HOXA4_MA1496.2 7 bp overlap
HOXA5 2 datasets
Motif DE_48h DE_48h-HOXA5_MA0158.2 8 bp overlap
Motif DE_72h DE_72h-HOXA5_MA0158.2 8 bp overlap
HOXB4 2 datasets
Motif DE_48h DE_48h-HOXB4_MA1499.2 6 bp overlap
Motif DE_72h DE_72h-HOXB4_MA1499.2 6 bp overlap
HOXC4 2 datasets
Motif DE_48h DE_48h-HOXC4_MA1504.2 6 bp overlap
Motif DE_72h DE_72h-HOXC4_MA1504.2 6 bp overlap
HOXD3 2 datasets
Motif DE_48h DE_48h-HOXD3_MA0912.2 8 bp overlap
Motif DE_72h DE_72h-HOXD3_MA0912.2 8 bp overlap
HOXD4 2 datasets
Motif DE_48h DE_48h-HOXD4_MA1507.2 6 bp overlap
Motif DE_72h DE_72h-HOXD4_MA1507.2 6 bp overlap
IFNA1 1 dataset
ChIP Huh-7_GFP GSE110511.IFNA1.Huh-7_GFP 249 bp overlap
JUN 4 datasets
ChIP DE_D2 S02-DE-d2-JUN-exp1 272 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 237 bp overlap
ChIP DE_D2 S54-DE-d2-JUN-exp2 436 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 227 bp overlap
KDM1A 2 datasets
ChIP K562 ENCFF128TYE 381 bp overlap
ChIP K562 ENCFF133OLU 371 bp overlap
KDM3A 1 dataset
ChIP 22Rv1_shKDM3A GSE109748.KDM3A.22Rv1_shKDM3A 139 bp overlap
KDM5B 1 dataset
ChIP K-562 ENCSR000AQA.KDM5B.K-562 114 bp overlap
Lef1 1 dataset
Motif DE_72h DE_72h-Lef1_MA0768.3 8 bp overlap
MAFF 2 datasets
Motif DE_48h DE_48h-MAFF_MA0495.4 11 bp overlap
Motif DE_72h DE_72h-MAFF_MA0495.4 11 bp overlap
MED26 1 dataset
ChIP HEK293T GSE121024.MED26.HEK293T 118 bp overlap
MGA 1 dataset
Motif DE_72h DE_72h-MGA_MA0801.1 8 bp overlap
MYBL2 1 dataset
ChIP Hep-G2 ENCSR581KCO.MYBL2.Hep-G2 139 bp overlap
Mafb 2 datasets
Motif DE_48h DE_48h-Mafb_MA0117.3 11 bp overlap
Motif DE_72h DE_72h-Mafb_MA0117.3 11 bp overlap
Mecom 1 dataset
Motif DE_72h DE_72h-Mecom_MA0029.2 11 bp overlap
Msgn1 2 datasets
Motif DE_48h DE_48h-Msgn1_MA1524.3 10 bp overlap
Motif DE_72h DE_72h-Msgn1_MA1524.3 10 bp overlap
NCAPH2 1 dataset
ChIP RMG-I GSE120058.NCAPH2.RMG-I 248 bp overlap
NR1D1 2 datasets
Motif DE_48h DE_48h-NR1D1_MA1531.2 14 bp overlap
Motif DE_72h DE_72h-NR1D1_MA1531.2 14 bp overlap
NR1I2 2 datasets
Motif DE_48h DE_48h-NR1I2_MA1533.2 15 bp overlap
Motif DE_72h DE_72h-NR1I2_MA1533.2 15 bp overlap
NR2C1 3 datasets
Motif DE_48h DE_48h-NR2C1_MA1535.2 6 bp overlap
Motif DE_72h DE_72h-NR2C1_MA1535.2 6 bp overlap
Motif DE_72h DE_72h-NR2C1_MA1535.2 6 bp overlap
NR2C2 3 datasets
Motif DE_48h DE_48h-NR2C2_MA1536.2 6 bp overlap
Motif DE_72h DE_72h-NR2C2_MA1536.2 6 bp overlap
Motif DE_72h DE_72h-NR2C2_MA1536.2 6 bp overlap
NR2F1 3 datasets
Motif DE_48h DE_48h-NR2F1_MA0017.3 12 bp overlap
Motif DE_72h DE_72h-NR2F1_MA0017.3 12 bp overlap
ChIP K-562 ENCSR970NKQ.NR2F1.K-562 243 bp overlap
NR2F2 2 datasets
Motif DE_48h DE_48h-NR2F2_MA1111.2 7 bp overlap
Motif DE_72h DE_72h-NR2F2_MA1111.2 7 bp overlap
NR2F6 1 dataset
ChIP K562 ENCFF674RQA 450 bp overlap
NR4A1 2 datasets
Motif DE_48h DE_48h-NR4A1_MA1112.3 8 bp overlap
Motif DE_72h DE_72h-NR4A1_MA1112.3 8 bp overlap
NR4A2 2 datasets
Motif DE_48h DE_48h-NR4A2_MA0160.3 8 bp overlap
Motif DE_72h DE_72h-NR4A2_MA0160.3 8 bp overlap
NRIP1 1 dataset
ChIP MCF-7_E2 ERP005838.NRIP1.MCF-7_E2 147 bp overlap
NRL 2 datasets
Motif DE_48h DE_48h-NRL_MA0842.3 12 bp overlap
Motif DE_72h DE_72h-NRL_MA0842.3 12 bp overlap
Nr1H2 3 datasets
Motif DE_48h DE_48h-Nr1H2_MA1996.2 6 bp overlap
Motif DE_72h DE_72h-Nr1H2_MA1996.2 6 bp overlap
Motif DE_72h DE_72h-Nr1H2_MA1996.2 6 bp overlap
Nr1H4 3 datasets
Motif DE_48h DE_48h-Nr1H4_MA1110.3 6 bp overlap
Motif DE_72h DE_72h-Nr1H4_MA1110.3 6 bp overlap
Motif DE_72h DE_72h-Nr1H4_MA1110.3 6 bp overlap
Nr1h3 3 datasets
Motif DE_48h DE_48h-Nr1h3_MA2337.1 6 bp overlap
Motif DE_72h DE_72h-Nr1h3_MA2337.1 6 bp overlap
Motif DE_72h DE_72h-Nr1h3_MA2337.1 6 bp overlap
Nr2F6 2 datasets
Motif DE_48h DE_48h-Nr2F6_MA0728.1 15 bp overlap
Motif DE_72h DE_72h-Nr2F6_MA0728.1 15 bp overlap
OTX1 1 dataset
Motif DE_72h DE_72h-OTX1_MA0711.2 6 bp overlap
PAF1 1 dataset
ChIP HCT-116_ab20662 GSE97527.PAF1.HCT-116_ab20662 188 bp overlap
PITX1 1 dataset
Motif DE_72h DE_72h-PITX1_MA0682.3 6 bp overlap
PITX3 1 dataset
Motif DE_72h DE_72h-PITX3_MA0714.2 6 bp overlap
PKNOX2 1 dataset
Motif DE_72h DE_72h-PKNOX2_MA0783.1 12 bp overlap
POU6F2 2 datasets
Motif DE_48h DE_48h-POU6F2_MA0793.2 9 bp overlap
Motif DE_72h DE_72h-POU6F2_MA0793.2 9 bp overlap
Ppara 2 datasets
Motif DE_48h DE_48h-Ppara_MA2338.1 7 bp overlap
Motif DE_72h DE_72h-Ppara_MA2338.1 7 bp overlap
Ptf1A 1 dataset
Motif DE_72h DE_72h-Ptf1A_MA1620.2 8 bp overlap
RAD21 1 dataset
ChIP HeLa-S3_CTCF-s-OE GSE108869.RAD21.HeLa-S3_CTCF-s-OE 142 bp overlap
RARA 2 datasets
Motif DE_48h DE_48h-RARA_MA0729.1 18 bp overlap
Motif DE_72h DE_72h-RARA_MA0729.1 18 bp overlap
RBM22 1 dataset
ChIP HepG2 ENCFF292RVQ 192 bp overlap
REST 6 datasets
Motif DE_48h DE_48h-REST_MA0138.3 20 bp overlap
Motif DE_72h DE_72h-REST_MA0138.3 20 bp overlap
ChIP H1 ENCFF429RUE 245 bp overlap
ChIP K-562 ENCSR000BMW.REST.K-562 134 bp overlap
ChIP K562 ENCFF430APM 231 bp overlap
ChIP WA01 ENCSR000BHM.REST.WA01 183 bp overlap
RHOXF1 1 dataset
Motif DE_72h DE_72h-RHOXF1_MA0719.2 6 bp overlap
RUNX3 1 dataset
Motif DE_72h DE_72h-RUNX3_MA0684.3 8 bp overlap
Rarb 2 datasets
Motif DE_48h DE_48h-Rarb_MA0857.1 16 bp overlap
Motif DE_72h DE_72h-Rarb_MA0857.1 16 bp overlap
Rarg 4 datasets
Motif DE_48h DE_48h-Rarg_MA0859.2 15 bp overlap
Motif DE_48h DE_48h-Rarg_MA0860.1 17 bp overlap
Motif DE_72h DE_72h-Rarg_MA0859.2 15 bp overlap
Motif DE_72h DE_72h-Rarg_MA0860.1 17 bp overlap
SMAD2 1 dataset
ChIP endoderm GSE29422.SMAD2.endoderm 197 bp overlap
SMAD2-3 5 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 551 bp overlap
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 213 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 662 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 309 bp overlap
ChIP HUVEC-C_TGFB1 GSE134556.SMAD2-3.HUVEC-C_TGFB1 756 bp overlap
SMAD2_3 4 datasets
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 431 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 304 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 821 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 821 bp overlap
SMAD3 4 datasets
ChIP H69_4TGF GSE145250.SMAD3.H69_4TGF 144 bp overlap
ChIP H69_5Veh GSE145250.SMAD3.H69_5Veh 139 bp overlap
ChIP SUM159PT GSE130364.SMAD3.SUM159PT 198 bp overlap
ChIP endoderm GSE29422.SMAD3.endoderm 195 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 211 bp overlap
SNAI2 1 dataset
Motif DE_72h DE_72h-SNAI2_MA0745.3 8 bp overlap
SNAI3 1 dataset
Motif DE_72h DE_72h-SNAI3_MA1559.2 9 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 336 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 374 bp overlap
SOX6 1 dataset
ChIP K562 ENCFF059YCJ 384 bp overlap
SUPT5H 2 datasets
ChIP DLD-1_NELFCD-AID GSE144786.SUPT5H.DLD-1_NELFCD-AID 295 bp overlap
ChIP HeLa_DOX GSE125534.SUPT5H.HeLa_DOX 82 bp overlap
SUPT6H 1 dataset
ChIP HCT-116 GSE130509.SUPT6H.HCT-116 166 bp overlap
T 3 datasets
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 183 bp overlap
ChIP H9_MESODERM GSE60606.T.H9_MESODERM 214 bp overlap
ChIP H9_MESODERM GSE60606.T.H9_MESODERM 173 bp overlap
TAL1 1 dataset
ChIP ProEs GSE59087.TAL1.ProEs 123 bp overlap
TBR1 1 dataset
Motif DE_72h DE_72h-TBR1_MA0802.2 9 bp overlap
TBX1 1 dataset
Motif DE_72h DE_72h-TBX1_MA0805.1 8 bp overlap
TBX15 1 dataset
Motif DE_72h DE_72h-TBX15_MA0803.1 8 bp overlap
TBX18 1 dataset
Motif DE_72h DE_72h-TBX18_MA1565.2 9 bp overlap
TBX2 1 dataset
Motif DE_72h DE_72h-TBX2_MA0688.2 9 bp overlap
TBX21 1 dataset
Motif DE_72h DE_72h-TBX21_MA0690.3 10 bp overlap
TBX3 1 dataset
Motif DE_72h DE_72h-TBX3_MA1566.3 9 bp overlap
TBX4 1 dataset
Motif DE_72h DE_72h-TBX4_MA0806.1 8 bp overlap
TBX5 1 dataset
Motif DE_72h DE_72h-TBX5_MA0807.1 8 bp overlap
TGIF1 1 dataset
Motif DE_72h DE_72h-TGIF1_MA0796.1 12 bp overlap
TGIF2 1 dataset
Motif DE_72h DE_72h-TGIF2_MA0797.1 12 bp overlap
TRPS1 1 dataset
Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap
Tbx6 1 dataset
Motif DE_72h DE_72h-Tbx6_MA1567.3 9 bp overlap
ZBTB18 1 dataset
Motif DE_72h DE_72h-ZBTB18_MA0698.2 11 bp overlap
ZEB1 1 dataset
Motif DE_72h DE_72h-ZEB1_MA0103.4 6 bp overlap
ZNF135 1 dataset
Motif DE_72h DE_72h-ZNF135_MA1587.1 14 bp overlap
ZNF354A 1 dataset
Motif DE_72h DE_72h-ZNF354A_MA1978.2 20 bp overlap
ZNF425 1 dataset
ChIP HEK293T GSE78099.ZNF425.HEK293T 70 bp overlap
ZNF460 1 dataset
Motif DE_72h DE_72h-ZNF460_MA1596.1 16 bp overlap
ZNF780A 1 dataset
ChIP HEK293T GSE78099.ZNF780A.HEK293T 195 bp overlap
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