chr1:212,909,569–212,910,174

chr1 : 212,909,569 – 212,910,174

605 bp 97 TFs 8 linked genes

This 605 bp open chromatin element is linked to 8 target genes and is bound by 97 transcription factors.

Linked Genes

8 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000282718		6.6 kb	Proximal	Proximity
VASH2		40.5 kb	Distal	Multiome+HiCAR
FLVCR1		51.8 kb	Distal	Multiome
FLVCR1-DT		52.0 kb	Distal	Multiome
ANGEL2		105.4 kb	Distal	Multiome
TATDN3		118.2 kb	Distal	Multiome
NSL1		118.3 kb	Distal	Multiome
RPS6KC1		141.2 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

97 transcription factors

ARNT::HIF1A 1 dataset

Motif ES_0h ES_0h-ARNTHIF1A_MA0259.2 5 bp overlap

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 542 bp overlap

ATF2 2 datasets

ChIP H1 ENCFF295GZO 512 bp overlap

ChIP WA01 ENCSR000BQU.ATF2.WA01 490 bp overlap

BCL11A 1 dataset

ChIP WA01 ENCSR000BIP.BCL11A.WA01 144 bp overlap

BCOR 2 datasets

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 177 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 214 bp overlap

BRD4 2 datasets

ChIP HAP1 GSE108387.BRD4.HAP1 409 bp overlap

ChIP HUVEC-C GSE60171.BRD4.HUVEC-C 261 bp overlap

CHD1 4 datasets

ChIP H1 ENCFF128BID 369 bp overlap

ChIP H1 ENCFF998XEK 403 bp overlap

ChIP WA01 ENCSR000AQK.CHD1.WA01 537 bp overlap

ChIP WA01 ENCSR000EBU.CHD1.WA01 453 bp overlap

ChIP WA01 ENCSR000EBT.CHD2.WA01 166 bp overlap

ChIP WA01 ENCSR000AVA.CHD7.WA01 400 bp overlap

CREB1 3 datasets

ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 167 bp overlap

ChIP WA01 ENCSR000BSN.CREB1.WA01 103 bp overlap

ChIP WA01 ENCSR000BSN.CREB1.WA01 260 bp overlap

ChIP hESC_NAIVE GSE69646.CTCF.hESC_NAIVE 362 bp overlap

ChIP NTERA2 GSE58641.DDX5.NTERA2 59 bp overlap

ChIP WTC11 ENCFF692RZJ 527 bp overlap

EP300 2 datasets

ChIP WA01 ENCSR000BKK.EP300.WA01 267 bp overlap

ChIP hESC GSE17917.EP300.hESC 293 bp overlap

ChIP WTC11 ENCFF011YUL 281 bp overlap

ChIP hESC ENCSR534VHI.ETS1.hESC 125 bp overlap

EZH2_phosphoT487 1 dataset

ChIP neuron_bipolar_doxy_4d ENCSR886KKK.EZH2_phosphoT487.neuron_bipolar_doxy_4d 350 bp overlap

FOXD3 1 dataset

Motif ES_0h ES_0h-FOXD3_MA0041.3 14 bp overlap

Foxq1 1 dataset

Motif ES_0h ES_0h-Foxq1_MA0040.2 10 bp overlap

GATA4 1 dataset

ChIP DE DE-GATA4-2 291 bp overlap

GATA6 5 datasets

ChIP DE DE-GATA6-2 290 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 386 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 123 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 408 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 338 bp overlap

Motif ES_0h ES_0h-GCM1_MA0646.2 10 bp overlap

Motif ES_0h ES_0h-GCM2_MA0767.2 8 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 272 bp overlap

HIF1A 1 dataset

Motif ES_0h ES_0h-HIF1A_MA1106.2 6 bp overlap

Motif ES_0h ES_0h-HLF_MA0043.4 9 bp overlap

HOXB13 1 dataset

ChIP 22Rv1 GSE96652.HOXB13.22Rv1 216 bp overlap

Hoxa13 1 dataset

Motif ES_0h ES_0h-Hoxa13_MA0650.4 8 bp overlap

ChIP K-562 GSE103215.ILF3.K-562 205 bp overlap

Motif ES_0h ES_0h-Irf1_MA0050.4 11 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 235 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 386 bp overlap

ChIP ESC S24-ESC-d0-JUN-exp1 306 bp overlap

ChIP ESC S34-ESC-d0-JUN-exp2 353 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 415 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 252 bp overlap

KLF4 4 datasets

ChIP HAP1 GSE130417.KLF4.HAP1 377 bp overlap

ChIP WA09 GSE105028.KLF4.WA09 453 bp overlap

ChIP WA09_heat-shock GSE105028.KLF4.WA09_heat-shock 230 bp overlap

ChIP hiPSC GSE56567.KLF4.hiPSC 232 bp overlap

ChIP WA01 ENCSR000EUP.MAX.WA01 305 bp overlap

ChIP hESC_PRIMED GSE69646.MED1.hESC_PRIMED 605 bp overlap

MEF2C 1 dataset

Motif ES_0h ES_0h-MEF2C_MA0497.2 11 bp overlap

MEIS1 1 dataset

Motif ES_0h ES_0h-MEIS1_MA0498.3 5 bp overlap

MORC2 1 dataset

ChIP H9 GSE95374.MORC2.H9 239 bp overlap

Motif ES_0h ES_0h-MXI1_MA1108.3 6 bp overlap

NANOG 10 datasets

ChIP GM23338 ENCFF065NZG 311 bp overlap

ChIP GM23338 ENCFF065NZG 154 bp overlap

ChIP GM23338 ENCSR061DGF.NANOG.GM23338 254 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 605 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 453 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 264 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 539 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 542 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 462 bp overlap

ChIP hESC GSE18292.NANOG.hESC 261 bp overlap

NFATC4 1 dataset

ChIP WTC11 ENCFF744MZI 271 bp overlap

NFIL3 1 dataset

Motif ES_0h ES_0h-NFIL3_MA0025.3 9 bp overlap

NIPBL 1 dataset

ChIP WA09_heat-shock GSE105028.NIPBL.WA09_heat-shock 376 bp overlap

ChIP fetal_testis GSE100639.PAX5.fetal_testis 213 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 185 bp overlap

POLR2A 2 datasets

ChIP H1 ENCFF770YBQ 398 bp overlap

ChIP H1 ENCFF770YBQ 93 bp overlap

POU2F1 1 dataset

Motif ES_0h ES_0h-POU2F1_MA0785.2 9 bp overlap

POU2F1::SOX2 1 dataset

Motif ES_0h ES_0h-POU2F1SOX2_MA1962.1 17 bp overlap

POU2F2 1 dataset

Motif ES_0h ES_0h-POU2F2_MA0507.3 13 bp overlap

POU2F3 1 dataset

Motif ES_0h ES_0h-POU2F3_MA0627.3 9 bp overlap

POU3F1 1 dataset

Motif ES_0h ES_0h-POU3F1_MA0786.2 10 bp overlap

POU3F2 1 dataset

Motif ES_0h ES_0h-POU3F2_MA0787.1 12 bp overlap

POU3F3 1 dataset

Motif ES_0h ES_0h-POU3F3_MA0788.1 13 bp overlap

POU3F4 1 dataset

Motif ES_0h ES_0h-POU3F4_MA0789.1 9 bp overlap

POU5F1 17 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 379 bp overlap

Motif ES_0h ES_0h-POU5F1_MA1115.2 7 bp overlap

ChIP GM23338 ENCFF333SNB 311 bp overlap

ChIP H1 ENCFF698ZAP 205 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 605 bp overlap

ChIP NCCIT GSE36134.POU5F1.NCCIT 459 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 605 bp overlap

ChIP OSKM GSE81899.POU5F1.OSKM 271 bp overlap

ChIP WA01 ENCSR000BMU.POU5F1.WA01 187 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 198 bp overlap

ChIP WA09 GSE105028.POU5F1.WA09 372 bp overlap

ChIP WA09_heat-shock GSE105028.POU5F1.WA09_heat-shock 368 bp overlap

ChIP hESC ENCSR264RJX.POU5F1.hESC 310 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 587 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 576 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 287 bp overlap

ChIP hiPSC_3s2 GSE81899.POU5F1.hiPSC_3s2 302 bp overlap

POU5F1B 1 dataset

Motif ES_0h ES_0h-POU5F1B_MA0792.1 9 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 289 bp overlap

PRRX2 1 dataset

ChIP WTC11 ENCFF107JGJ 301 bp overlap

Pou5f1::Sox2 2 datasets

Motif ES_0h ES_0h-Pou5f1Sox2_MA0142.1 15 bp overlap

Motif ES_0h ES_0h-Pou5f1Sox2_MA0142.1 15 bp overlap

RAD21 4 datasets

ChIP HAP1 GSE126634.RAD21.HAP1 348 bp overlap

ChIP HAP1 GSE152721.RAD21.HAP1 312 bp overlap

ChIP HAP1_CTCF GSE126634.RAD21.HAP1_CTCF 432 bp overlap

ChIP HAP1_clone25 GSE152721.RAD21.HAP1_clone25 250 bp overlap

SIN3A 1 dataset

ChIP WA01 ENCSR000BIS.SIN3A.WA01 142 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8 GSE109524.SMAD2-3.HUES-8 285 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 338 bp overlap

SMAD2_3 3 datasets

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 383 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 204 bp overlap

ChIP ESC S33-ESC-d0-SMAD2_3-exp2 303 bp overlap

SMAD3 2 datasets

ChIP BG03 GSE21614.SMAD3.BG03 255 bp overlap

ChIP BG03_DIFF_0H GSE36578.SMAD3.BG03_DIFF_0H 230 bp overlap

SMARCA4 2 datasets

ChIP hiPSC GSE124903.SMARCA4.hiPSC 508 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 512 bp overlap

SMARCB1 2 datasets

ChIP hiPSC GSE124903.SMARCB1.hiPSC 246 bp overlap

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 534 bp overlap

SMARCC1 3 datasets

ChIP DE_D1 S10-DE-d1-BAF155-exp1 245 bp overlap

ChIP hiPSC GSE124903.SMARCC1.hiPSC 348 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 396 bp overlap

SOX13 1 dataset

Motif ES_0h ES_0h-SOX13_MA1120.2 7 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 260 bp overlap

SOX2 5 datasets

Motif ES_0h ES_0h-SOX2_MA0143.5 7 bp overlap

ChIP OSKM GSE81899.SOX2.OSKM 246 bp overlap

ChIP hESC GSE69479.SOX2.hESC 311 bp overlap

ChIP hESC GSE18292.SOX2.hESC 230 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 421 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 281 bp overlap

ChIP WA01 ENCSR000BQV.SP4.WA01 375 bp overlap

Motif ES_0h ES_0h-Sox3_MA0514.3 7 bp overlap

Motif ES_0h ES_0h-Sox5_MA0087.3 8 bp overlap

TAF1 2 datasets

ChIP H1 ENCFF478SZO 405 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 375 bp overlap

TAF7 2 datasets

ChIP H1 ENCFF061XZZ 312 bp overlap

ChIP WA01 ENCSR000BLU.TAF7.WA01 460 bp overlap

ChIP H1 ENCFF859IIO 377 bp overlap

ChIP WA01 ENCSR000ECB.TBP.WA01 271 bp overlap

ChIP hESC GSE122298.TBP.hESC 254 bp overlap

ChIP hESC_10h GSE122298.TBP.hESC_10h 233 bp overlap

ChIP hESC_2h GSE122298.TBP.hESC_2h 255 bp overlap

ChIP hESC_8h GSE122298.TBP.hESC_8h 178 bp overlap

TCF12 1 dataset

ChIP WA01 ENCSR000BIT.TCF12.WA01 229 bp overlap

ChIP NPC GSE154479.TCF3.NPC 447 bp overlap

TFAP2C 1 dataset

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 227 bp overlap

TP53 3 datasets

ChIP H9 GSE142050.TP53.H9 323 bp overlap

ChIP H9_ectoderm GSE142050.TP53.H9_ectoderm 289 bp overlap

ChIP hESC_DAMAGED GSE39912.TP53.hESC_DAMAGED 244 bp overlap

ChIP NT2-D1 ENCSR000EXG.YY1.NT2-D1 160 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 497 bp overlap

ZBTB33 1 dataset

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 119 bp overlap

ZNF114 1 dataset

ChIP GM23338 ENCSR555KFE.ZNF114.GM23338 231 bp overlap

ZNF157 1 dataset

Motif ES_0h ES_0h-ZNF157_MA2331.1 21 bp overlap

ZNF207 1 dataset

ChIP WA09 GSE118632.ZNF207.WA09 458 bp overlap

ZNF416 1 dataset

ChIP WTC11 ENCFF407TAZ 271 bp overlap

ZNF425 2 datasets

ChIP WTC11 ENCFF359IXT 301 bp overlap

ChIP WTC11 ENCFF359IXT 301 bp overlap

ZNF449 1 dataset

Motif ES_0h ES_0h-ZNF449_MA1656.2 10 bp overlap

ZNF454 1 dataset

Motif ES_0h ES_0h-ZNF454_MA1712.2 17 bp overlap

ZNF462 1 dataset

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 179 bp overlap

ZNF528 2 datasets

Motif ES_0h ES_0h-ZNF528_MA1597.1 17 bp overlap

ChIP HEK293 GSE76494.ZNF528.HEK293 188 bp overlap

ZNF532 1 dataset

ChIP WTC11 ENCFF373VBX 274 bp overlap

ZNF558 1 dataset

Motif ES_0h ES_0h-ZNF558_MA2335.1 29 bp overlap

ZNF582 1 dataset

Motif ES_0h ES_0h-ZNF582_MA1983.2 19 bp overlap

ZNF671 2 datasets

ChIP WTC11 ENCFF053HBV 265 bp overlap

ChIP WTC11 ENCFF053HBV 265 bp overlap

ZNF677 1 dataset

Motif ES_0h ES_0h-ZNF677_MA2101.1 12 bp overlap

Motif ES_0h ES_0h-ZNF8_MA1718.1 20 bp overlap