chr10:99,527,131–99,527,911

chr10 : 99,527,131 – 99,527,911

780 bp 89 TFs 7 linked genes

This 780 bp open chromatin element is linked to 7 target genes and is bound by 89 transcription factors.

Linked Genes

7 genes

Gene	Expression	Dist. to TSS	Distance	Link type
LINC01475		at TSS	At TSS	Proximity
NKX2-3		5.0 kb	Proximal	Proximity
SLC25A28		92.9 kb	Distal	Multiome
GOT1		96.9 kb	Distal	Multiome
ENTPD7		132.0 kb	Distal	Multiome
COX15		204.6 kb	Distal	Multiome
CUTC		204.7 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

89 transcription factors

ChIP MCF-7 GSE144036.AFF4.MCF-7 341 bp overlap

AGO1 2 datasets

ChIP Hep-G2 GSE120104.AGO1.Hep-G2 275 bp overlap

ChIP Hep-G2 ENCSR555ZMV.AGO1.Hep-G2 515 bp overlap

ChIP MDA-MB-453 ERP003503.AR.MDA-MB-453 256 bp overlap

ARNTL 1 dataset

ChIP NSC_hNP1 GSE134972.ARNTL.NSC_hNP1 203 bp overlap

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 780 bp overlap

BCOR 2 datasets

ChIP WA01_KDM2B_KO GSE104690.BCOR.WA01_KDM2B_KO 780 bp overlap

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 780 bp overlap

ChIP HUES-64 GSE104059.BRD1.HUES-64 321 bp overlap

BRD4 5 datasets

ChIP COLO-741 GSE73319.BRD4.COLO-741 270 bp overlap

ChIP MCF-10A ERP003925.BRD4.MCF-10A 629 bp overlap

ChIP T-47D ERP003925.BRD4.T-47D 359 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 524 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 201 bp overlap

ChIP ME-1 GSE46044.CBFB.ME-1 425 bp overlap

ChIP H1 ENCFF095JHA 266 bp overlap

ChIP HCT-116 GSE72622.CDK9.HCT-116 233 bp overlap

CHD1 3 datasets

ChIP WA01 ENCSR000AQK.CHD1.WA01 215 bp overlap

ChIP hMSC-TERT GSE89179.CHD1.hMSC-TERT 530 bp overlap

ChIP hMSC-TERT_osteoblast GSE89179.CHD1.hMSC-TERT_osteoblast 772 bp overlap

CTBP2 3 datasets

ChIP H1 ENCFF329MAX 215 bp overlap

ChIP WA01 ENCSR000EUO.CTBP2.WA01 278 bp overlap

ChIP WA01 ENCSR000EUO.CTBP2.WA01 331 bp overlap

CTCF 4 datasets

ChIP T-47D_NaCl-isotonic GSE111923.CTCF.T-47D_NaCl-isotonic 349 bp overlap

ChIP T-47D_NaCl-isotonic-triptolide GSE111923.CTCF.T-47D_NaCl-isotonic-triptolide 395 bp overlap

ChIP T-47D_NaCl-triptolide GSE111923.CTCF.T-47D_NaCl-triptolide 433 bp overlap

ChIP T-47D_Y537S GSE148277.CTCF.T-47D_Y537S 235 bp overlap

CTCFL 1 dataset

ChIP K-562 GSE70764.CTCFL.K-562 216 bp overlap

ChIP ProEs GSE59087.EED.ProEs 203 bp overlap

ChIP H1 ENCFF451BLH 63 bp overlap

ChIP CD34_NR29 GSE23730.ERG.CD34_NR29 367 bp overlap

ChIP MCF-7 GSE23730.ERG.MCF-7 394 bp overlap

ChIP ME-1 GSE46044.ERG.ME-1 228 bp overlap

ESR1 5 datasets

ChIP Ishikawa GSE99905.ESR1.Ishikawa 418 bp overlap

ChIP Ishikawa_DMSO_D538G_clone3 GSE132426.ESR1.Ishikawa_DMSO_D538G_clone3 260 bp overlap

ChIP Ishikawa_siNTC-96h GSE129803.ESR1.Ishikawa_siNTC-96h 294 bp overlap

ChIP MCF-7_PaPE-1 GSE93510.ESR1.MCF-7_PaPE-1 425 bp overlap

ChIP T-47D GSE148277.ESR1.T-47D 231 bp overlap

ETS1 2 datasets

ChIP GM23338 ENCFF701IZH 105 bp overlap

ChIP cardiomyocyte_D0 GSE129986.ETS1.cardiomyocyte_D0 519 bp overlap

ChIP WTC11 ENCFF812SCD 72 bp overlap

EZH2 34 datasets

ChIP A673 ENCFF790MVL 489 bp overlap

ChIP B cell ENCFF803EMO 182 bp overlap

ChIP GM23248 ENCFF404ZHM 411 bp overlap

ChIP GM23248 ENCFF404ZHM 98 bp overlap

ChIP GM23338 ENCFF613YON 780 bp overlap

ChIP GM23338 ENCFF886DXX 370 bp overlap

ChIP H1 ENCFF232NZA 780 bp overlap

ChIP HUVEC-C GSE109625.EZH2.HUVEC-C 780 bp overlap

ChIP HUVEC-C_VEGF_12h GSE109625.EZH2.HUVEC-C_VEGF_12h 142 bp overlap

ChIP HUVEC-C_VEGF_12h GSE109625.EZH2.HUVEC-C_VEGF_12h 538 bp overlap

ChIP HUVEC-C_VEGF_1h GSE109625.EZH2.HUVEC-C_VEGF_1h 751 bp overlap

ChIP HUVEC-C_VEGF_4h GSE109625.EZH2.HUVEC-C_VEGF_4h 780 bp overlap

ChIP Hep-3B2-1-7 GSE128137.EZH2.Hep-3B2-1-7 686 bp overlap

ChIP HepG2 ENCFF912EIW 198 bp overlap

ChIP SU-DHL-6 GSE134136.EZH2.SU-DHL-6 400 bp overlap

ChIP astrocyte ENCFF365JTP 780 bp overlap

ChIP dermal-fibroblast_Transformed GSE126396.EZH2.dermal-fibroblast_Transformed 151 bp overlap

ChIP dermal-fibroblast_Transformed GSE126396.EZH2.dermal-fibroblast_Transformed 94 bp overlap

ChIP endothelial cell of umbilical vein ENCFF539AKL 780 bp overlap

ChIP fibroblast of dermis ENCFF029VZK 398 bp overlap

ChIP fibroblast of dermis ENCFF029VZK 352 bp overlap

ChIP fibroblast of lung ENCFF479BAW 446 bp overlap

ChIP hESC GSE113817.EZH2.hESC 638 bp overlap

ChIP hepatocyte ENCFF552DZB 325 bp overlap

ChIP keratinocyte ENCFF070STK 196 bp overlap

ChIP mammary epithelial cell ENCFF224GAI 394 bp overlap

ChIP mammary epithelial cell ENCFF224GAI 60 bp overlap

ChIP myotube ENCSR000ASZ.EZH2.myotube 713 bp overlap

ChIP neural ENCSR511CUH.EZH2.neural 780 bp overlap

ChIP neural cell ENCFF610EPB 99 bp overlap

ChIP neural cell ENCFF610EPB 401 bp overlap

ChIP neural cell ENCFF610EPB 401 bp overlap

ChIP neural progenitor cell ENCFF018MKA 780 bp overlap

ChIP neural progenitor cell ENCFF472NFV 780 bp overlap

FLI1 2 datasets

ChIP TSU-1621MT GSE60477.FLI1.TSU-1621MT 319 bp overlap

ChIP UAE_ZINC GSE23730.FLI1.UAE_ZINC 264 bp overlap

FOXA2 1 dataset

ChIP BJ1-hTERT_FoxHnf1aCoExp GSE90454.FOXA2.BJ1-hTERT_FoxHnf1aCoExp 389 bp overlap

GABPA 1 dataset

ChIP K-562 ENCSR000BLO.GABPA.K-562 133 bp overlap

GATA4 1 dataset

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 73 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 171 bp overlap

GTF3C2 1 dataset

ChIP H9 GSE94418.GTF3C2.H9 204 bp overlap

HDAC2 1 dataset

ChIP K-562 ENCSR000AQG.HDAC2.K-562 143 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 352 bp overlap

HIF1A 1 dataset

ChIP BEAS-2B_arsenic GSE145834.HIF1A.BEAS-2B_arsenic 376 bp overlap

INO80 2 datasets

ChIP Hep-G2 GSE97411.INO80.Hep-G2 780 bp overlap

ChIP Hep-G2 GSE107730.INO80.Hep-G2 360 bp overlap

JARID2 3 datasets

ChIP AMIPS6 GSE48516.JARID2.AMIPS6 780 bp overlap

ChIP AMIPS8 GSE48516.JARID2.AMIPS8 780 bp overlap

ChIP MRC-5_IPS25 GSE48516.JARID2.MRC-5_IPS25 780 bp overlap

ChIP ESC S24-ESC-d0-JUN-exp1 312 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 465 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 159 bp overlap

ChIP MCF-7_abemaciclib GSE157385.JUN.MCF-7_abemaciclib 277 bp overlap

KDM4A 2 datasets

ChIP H1 ENCFF078LED 610 bp overlap

ChIP WA01 ENCSR000AVC.KDM4A.WA01 535 bp overlap

KDM5B 1 dataset

ChIP SUM185_SHCTCF GSE46055.KDM5B.SUM185_SHCTCF 114 bp overlap

KDM6B 1 dataset

ChIP CUTLL1 GSE56694.KDM6B.CUTLL1 434 bp overlap

KMT2A 1 dataset

ChIP OCI-AML-3_VTP GSE129636.KMT2A.OCI-AML-3_VTP 780 bp overlap

ChIP THP-1_macrophage_PMA GSE96800.MAF1.THP-1_macrophage_PMA 190 bp overlap

ChIP OCI-AML-3_VTP GSE129636.MEN1.OCI-AML-3_VTP 592 bp overlap

ChIP DU145_SH4 GSE135623.MTF2.DU145_SH4 523 bp overlap

NANOG 2 datasets

ChIP WA01 ERP004238.NANOG.WA01 234 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 281 bp overlap

NCAPH2 1 dataset

ChIP HEK293 GSE97540.NCAPH2.HEK293 386 bp overlap

OGG1 4 datasets

ChIP HEK293 GSE89017.OGG1.HEK293 519 bp overlap

ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 488 bp overlap

ChIP HEK293_30_min GSE89017.OGG1.HEK293_30_min 316 bp overlap

ChIP HEK293_60_min GSE89017.OGG1.HEK293_60_min 527 bp overlap

PCBP1 1 dataset

ChIP Hep-G2 GSE120104.PCBP1.Hep-G2 171 bp overlap

PCBP2 2 datasets

ChIP Hep-G2 ENCSR945NSF.PCBP2.Hep-G2 56 bp overlap

ChIP Hep-G2 GSE120104.PCBP2.Hep-G2 56 bp overlap

PCGF2 1 dataset

ChIP NT2-D1 GSE101538.PCGF2.NT2-D1 107 bp overlap

PHF19 1 dataset

ChIP DU145_CTR GSE135623.PHF19.DU145_CTR 74 bp overlap

POLR2A 8 datasets

ChIP neural cell ENCFF604SPB 195 bp overlap

ChIP sigmoid colon ENCFF101ILL 192 bp overlap

ChIP sigmoid colon ENCFF725QFT 417 bp overlap

ChIP sigmoid colon ENCFF725QFT 319 bp overlap

ChIP sigmoid colon ENCFF754JQR 128 bp overlap

ChIP spleen ENCFF044PYR 382 bp overlap

ChIP spleen ENCFF446ZGT 780 bp overlap

ChIP spleen ENCFF706IUS 613 bp overlap

POU2F1 2 datasets

ChIP T-47D GSE148277.POU2F1.T-47D 368 bp overlap

ChIP T-47D_D538G GSE148277.POU2F1.T-47D_D538G 604 bp overlap

POU5F1 4 datasets

ChIP BG03 GSE21614.POU5F1.BG03 229 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 780 bp overlap

ChIP SKM-1 GSE93706.POU5F1.SKM-1 256 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 636 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 780 bp overlap

RBBP5 2 datasets

ChIP H1 ENCFF905HFL 366 bp overlap

ChIP WA01 ENCSR000AQC.RBBP5.WA01 183 bp overlap

RBFOX2 1 dataset

ChIP K-562 ENCSR822LBD.RBFOX2.K-562 225 bp overlap

ChIP HEK293_TNF-1h GSE75562.RELA.HEK293_TNF-1h 780 bp overlap

RING1 1 dataset

ChIP SYO-1_shCt GSE139053.RING1.SYO-1_shCt 386 bp overlap

RNF2 3 datasets

ChIP H1 ENCFF239FFS 780 bp overlap

ChIP HUES-64 GSE104059.RNF2.HUES-64 449 bp overlap

ChIP Hep-G2 ENCSR523XCR.RNF2.Hep-G2 168 bp overlap

RORC 2 datasets

ChIP HCC70 GSE126380.RORC.HCC70 461 bp overlap

ChIP HCC70_XY018 GSE126380.RORC.HCC70_XY018 512 bp overlap

RUNX1 2 datasets

ChIP AML_Blast GSE60130.RUNX1.AML_Blast 148 bp overlap

ChIP CD34 GSE64862.RUNX1.CD34 148 bp overlap

ChIP TSU-1621MT GSE60477.RXR.TSU-1621MT 335 bp overlap

SALL3 1 dataset

ChIP hiPSC GSE104863.SALL3.hiPSC 649 bp overlap

SMAD2-3 4 datasets

ChIP HUES-8 GSE109524.SMAD2-3.HUES-8 166 bp overlap

ChIP HUES-8 GSE109524.SMAD2-3.HUES-8 480 bp overlap

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 349 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 119 bp overlap

SMARCC1 5 datasets

ChIP Aska-SS GSE108025.SMARCC1.Aska-SS 273 bp overlap

ChIP ESC S25-ESC-d0-BAF155-exp1 749 bp overlap

ChIP SYO-1_shCt GSE139053.SMARCC1.SYO-1_shCt 533 bp overlap

ChIP SYO-1_shRING1A-B GSE139053.SMARCC1.SYO-1_shRING1A-B 201 bp overlap

ChIP SYO-1_shRING1A-B GSE139053.SMARCC1.SYO-1_shRING1A-B 388 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 465 bp overlap

SREBP2 2 datasets

ChIP HCC70 GSE126380.SREBP2.HCC70 458 bp overlap

ChIP HCC70_XY018 GSE126380.SREBP2.HCC70_XY018 543 bp overlap

SS18 2 datasets

ChIP Aska-SS GSE108025.SS18.Aska-SS 642 bp overlap

ChIP Aska-SS_BAF47KO1 GSE108025.SS18.Aska-SS_BAF47KO1 217 bp overlap

SUZ12 7 datasets

ChIP H1 ENCFF507HGF 271 bp overlap

ChIP H1 ENCFF881NFR 780 bp overlap

ChIP NCCIT GSE71675.SUZ12.NCCIT 780 bp overlap

ChIP NT2-D1 GSE101538.SUZ12.NT2-D1 600 bp overlap

ChIP NT2/D1 ENCFF574SXS 225 bp overlap

ChIP WA01 ENCSR000ATS.SUZ12.WA01 780 bp overlap

ChIP WA01 ENCSR000EUQ.SUZ12.WA01 780 bp overlap

TAF15 2 datasets

ChIP Hep-G2 ENCSR825MZS.TAF15.Hep-G2 268 bp overlap

ChIP Hep-G2 GSE120104.TAF15.Hep-G2 353 bp overlap

ChIP H1 ENCFF859IIO 368 bp overlap

ChIP H1 ENCFF859IIO 377 bp overlap

ChIP WA01 ENCSR000ECB.TBP.WA01 235 bp overlap

TCF12 1 dataset

ChIP WA01 ENCSR000BIT.TCF12.WA01 72 bp overlap

TFAP2C 2 datasets

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 780 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 473 bp overlap

TFIIIC 1 dataset

ChIP HEK293 GSE119418.TFIIIC.HEK293 302 bp overlap

ChIP HCT-116_IR GSE60267.TP53.HCT-116_IR 56 bp overlap

TRIM25 1 dataset

ChIP BT-549 GSE79588.TRIM25.BT-549 383 bp overlap

TRIM28 2 datasets

ChIP AF22 GSE84259.TRIM28.AF22 445 bp overlap

ChIP hESC GSE115387.TRIM28.hESC 574 bp overlap

ChIP SMMC-7721 GSE126982.WDR5.SMMC-7721 428 bp overlap

XRCC5 1 dataset

ChIP K-562 GSE120104.XRCC5.K-562 146 bp overlap

ZBTB48 2 datasets

ChIP U2OS GSE96776.ZBTB48.U2OS 377 bp overlap

ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 755 bp overlap

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 647 bp overlap

ZNF121 1 dataset

ChIP WTC11 ENCFF291API 297 bp overlap

ZNF148 1 dataset

ChIP K-562 GSE121133.ZNF148.K-562 107 bp overlap

ZNF263 1 dataset

ChIP HEK293 ENCFF336CWQ 323 bp overlap

ZNF366 1 dataset

ChIP HEK293 ENCFF799ATK 144 bp overlap

ZNF398 2 datasets

ChIP H9 GSE133630.ZNF398.H9 90 bp overlap

ChIP HEK293 ENCFF184XEW 91 bp overlap

ZNF407 1 dataset

ChIP Hep-G2 ENCSR005WGY.ZNF407.Hep-G2 142 bp overlap

ZNF444 1 dataset

ChIP MCF-7 ENCSR038XIA.ZNF444.MCF-7 104 bp overlap

ZNF711 1 dataset

ChIP HEK293T GSE145160.ZNF711.HEK293T 754 bp overlap

ZNF800 5 datasets

ChIP Hep-G2 ENCSR701WPG.ZNF800.Hep-G2 476 bp overlap

ChIP Hep-G2 ENCSR701WPG.ZNF800.Hep-G2 56 bp overlap

ChIP HepG2 ENCFF840FYM 621 bp overlap

ChIP HepG2 ENCFF840FYM 443 bp overlap

ChIP HepG2 ENCFF840FYM 229 bp overlap

ZNF891 1 dataset

ChIP Hep-G2 ENCSR020CLV.ZNF891.Hep-G2 412 bp overlap