chr9 : 14,906,725 – 14,907,004
279 bp 92 TFs 1 linked gene
This 279 bp open chromatin element is linked to FREM1 and is bound by 92 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
FREM1 3.4 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr9:14,901,725 – 14,912,004
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
92 transcription factors
Source
Cell type
AR 9 datasets
ChIP DUCAP_ANDROGEN GSE70679.AR.DUCAP_ANDROGEN 108 bp overlap
ChIP LNCaP_1F5_SIFOXA1 GSE30623.AR.LNCaP_1F5_SIFOXA1 127 bp overlap
ChIP LNCaP_r1881 GSE94682.AR.LNCaP_r1881 182 bp overlap
ChIP VCaP_DHAT_2H GSE28950.AR.VCaP_DHAT_2H 189 bp overlap
ChIP VCaP_R1881_30M GSE84432.AR.VCaP_R1881_30M 214 bp overlap
ChIP VCaP_R1881_4H GSE84432.AR.VCaP_R1881_4H 254 bp overlap
ChIP VCaP_SH1_R1881 GSE79128.AR.VCaP_SH1_R1881 220 bp overlap
ChIP VCaP_SH2_DHT GSE79128.AR.VCaP_SH2_DHT 266 bp overlap
ChIP VCaP_SH2_R1881 GSE79128.AR.VCaP_SH2_R1881 242 bp overlap
ARID1B 2 datasets
ChIP K-562 ENCSR822CCM.ARID1B.K-562 279 bp overlap
ChIP K562 ENCFF938UXQ 279 bp overlap
BCL11A 4 datasets
ChIP CD34_Day9_15min GSE104676.BCL11A.CD34_Day9_15min 65 bp overlap
ChIP CD34_Day9_30min GSE104676.BCL11A.CD34_Day9_30min 87 bp overlap
ChIP CD34_Day9_60min GSE104676.BCL11A.CD34_Day9_60min 65 bp overlap
ChIP CD34_Day9_90min GSE104676.BCL11A.CD34_Day9_90min 128 bp overlap
BCL6B 2 datasets
ChIP HEK293 ENCFF555YRB 279 bp overlap
ChIP HEK293 ENCSR673SGK.BCL6B.HEK293 223 bp overlap
BRD2 1 dataset
ChIP K-562 GSE140325.BRD2.K-562 156 bp overlap
BRD4 3 datasets
ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 181 bp overlap
ChIP SK-N-BE2-C_Naive-veh GSE107706.BRD4.SK-N-BE2-C_Naive-veh 124 bp overlap
ChIP SK-N-BE2-C_Resistant-veh GSE107706.BRD4.SK-N-BE2-C_Resistant-veh 279 bp overlap
CBFA2T2 2 datasets
ChIP K-562 ENCSR699PVC.CBFA2T2.K-562 274 bp overlap
ChIP K562 ENCFF963TXY 234 bp overlap
CBFA2T3 3 datasets
ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 279 bp overlap
ChIP K-562 GSE142227.CBFA2T3.K-562 250 bp overlap
ChIP K562 ENCFF673OEZ 279 bp overlap
CDK8 2 datasets
ChIP leiomyoma_PT886 GSE128230.CDK8.leiomyoma_PT886 136 bp overlap
ChIP myometrium_PT1063 GSE128230.CDK8.myometrium_PT1063 58 bp overlap
CEBPD 1 dataset
ChIP K-562 ENCSR000BVY.CEBPD.K-562 171 bp overlap
CHD2 1 dataset
ChIP SK-N-SH ENCSR274SLQ.CHD2.SK-N-SH 234 bp overlap
CREB5 1 dataset
ChIP SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour ENCSR758GOA.CREB5.SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour 156 bp overlap
CTBP1 2 datasets
ChIP K-562 ENCSR201NQZ.CTBP1.K-562 279 bp overlap
ChIP K562 ENCFF403WPG 188 bp overlap
CTCF 1 dataset
ChIP HUDEP-2_30min GSE104676.CTCF.HUDEP-2_30min 82 bp overlap
DACH1 1 dataset
ChIP K-562 ENCSR030TJP.DACH1.K-562 149 bp overlap
DPF2 2 datasets
ChIP K-562 ENCSR219BXP.DPF2.K-562 279 bp overlap
ChIP K562 ENCFF775HUO 240 bp overlap
EBF3_P177L 1 dataset
ChIP SK-N-SH GSE90682.EBF3_P177L.SK-N-SH 222 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 151 bp overlap
EP300 3 datasets
ChIP K-562 ENCSR000EGE.EP300.K-562 203 bp overlap
ChIP SK-N-SH ENCFF829RWA 257 bp overlap
ChIP SK-N-SH ENCSR000EHV.EP300.SK-N-SH 251 bp overlap
ESRRA 1 dataset
ChIP K-562 ENCSR486IFJ.ESRRA.K-562 276 bp overlap
ESRRG 1 dataset
ChIP cardiomyocyte GSE113760.ESRRG.cardiomyocyte 279 bp overlap
FEZF1 1 dataset
ChIP HEK293 ENCSR827NWO.FEZF1.HEK293 84 bp overlap
FOXM1 3 datasets
ChIP K-562 ENCSR429QPP.FOXM1.K-562 269 bp overlap
ChIP K562 ENCFF255RHV 279 bp overlap
ChIP K562 ENCFF255RHV 152 bp overlap
GATA1 13 datasets
ChIP CD34_Day7_30min GSE104676.GATA1.CD34_Day7_30min 263 bp overlap
ChIP CD34_ERYTH_BIO GSE29194.GATA1.CD34_ERYTH_BIO 279 bp overlap
ChIP CD34_ERYTH_BMP GSE29194.GATA1.CD34_ERYTH_BMP 265 bp overlap
ChIP HUDEP-2_30min GSE104676.GATA1.HUDEP-2_30min 242 bp overlap
ChIP K-562 GSE107726.GATA1.K-562 279 bp overlap
ChIP K-562 ENCSR000EFT.GATA1.K-562 214 bp overlap
ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 279 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 279 bp overlap
ChIP K562 ENCFF094CMK 245 bp overlap
ChIP erythroblast ENCFF867JAR 279 bp overlap
ChIP erythroblast ENCSR000EXP.GATA1.erythroblast 279 bp overlap
ChIP erythroid_Don001 GSE137982.GATA1.erythroid_Don001 279 bp overlap
ChIP erythroid_Don003 GSE137982.GATA1.erythroid_Don003 279 bp overlap
GATA2 10 datasets
ChIP CD34_ACY957 GSE60792.GATA2.CD34_ACY957 231 bp overlap
ChIP K-562 ENCSR000DKA.GATA2.K-562 279 bp overlap
ChIP K-562 ENCSR000EWG.GATA2.K-562 242 bp overlap
ChIP K-562 ENCSR000BKM.GATA2.K-562 177 bp overlap
ChIP K562 ENCFF513FTZ 279 bp overlap
ChIP K562 ENCFF544PCK 251 bp overlap
ChIP SH-SY5Y ENCSR000EYB.GATA2.SH-SY5Y 279 bp overlap
ChIP SK-N-SH ENCFF764OZD 279 bp overlap
ChIP SK-N-SH ENCSR706VOO.GATA2.SK-N-SH 206 bp overlap
ChIP TF1 GSE73207.GATA2.TF1 279 bp overlap
GATA3 2 datasets
ChIP Kelly GSE65664.GATA3.Kelly 165 bp overlap
ChIP SH-SY5Y ENCSR000EXZ.GATA3.SH-SY5Y 279 bp overlap
GATA4 12 datasets
ChIP DE DE-GATA4-1 279 bp overlap
ChIP DE DE-GATA4-2 279 bp overlap
ChIP G296S GSE85628.GATA4.G296S 279 bp overlap
ChIP G296S_2 GSE85628.GATA4.G296S_2 279 bp overlap
ChIP G296S_4 GSE85628.GATA4.G296S_4 215 bp overlap
ChIP Hep-G2 GSE135714.GATA4.Hep-G2 279 bp overlap
ChIP cardiomyocyte GSE85628.GATA4.cardiomyocyte 238 bp overlap
ChIP cardiomyocyte_1 GSE85628.GATA4.cardiomyocyte_1 239 bp overlap
ChIP cardiomyocyte_5 GSE85628.GATA4.cardiomyocyte_5 165 bp overlap
ChIP cardiomyocyte_7 GSE85628.GATA4.cardiomyocyte_7 279 bp overlap
ChIP foregut GSE117136.GATA4.foregut 279 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 279 bp overlap
GATA6 14 datasets
ChIP DE DE-GATA6-1 279 bp overlap
ChIP DE DE-GATA6-2 279 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 279 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 279 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 279 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 279 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 279 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 279 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 279 bp overlap
ChIP foregut GSE117136.GATA6.foregut 279 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 279 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 279 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 279 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 279 bp overlap
GFI1B 1 dataset
ChIP K-562 ENCSR509GDT.GFI1B.K-562 182 bp overlap
HAND2 3 datasets
ChIP CLB-Ga GSE90683.HAND2.CLB-Ga 279 bp overlap
ChIP Kelly GSE94822.HAND2.Kelly 279 bp overlap
ChIP SK-N-BE2-C GSE94822.HAND2.SK-N-BE2-C 241 bp overlap
HDAC1 3 datasets
ChIP K-562 ENCSR711VWL.HDAC1.K-562 168 bp overlap
ChIP K-562 ENCSR387UWP.HDAC1.K-562 279 bp overlap
ChIP K-562_dilution-6-100 GSE140325.HDAC1.K-562_dilution-6-100 153 bp overlap
HDAC2 4 datasets
ChIP K-562 ENCSR893WSB.HDAC2.K-562 269 bp overlap
ChIP K-562 GSE140325.HDAC2.K-562 229 bp overlap
ChIP K-562 ENCSR075HTM.HDAC2.K-562 217 bp overlap
ChIP K562 ENCFF744ALD 279 bp overlap
HIC2 1 dataset
Motif DE_60h DE_60h-HIC2_MA0738.2 6 bp overlap
IKZF1 3 datasets
ChIP K-562 ENCSR395HWC.IKZF1.K-562 279 bp overlap
ChIP K562 ENCFF348IBL 229 bp overlap
ChIP K562 ENCFF771OHZ 279 bp overlap
ILF3 1 dataset
ChIP K-562 GSE103215.ILF3.K-562 215 bp overlap
ISL1 1 dataset
ChIP SK-N-BE2-C GSE94822.ISL1.SK-N-BE2-C 212 bp overlap
KDM1A 5 datasets
ChIP K-562 GSE117944.KDM1A.K-562 279 bp overlap
ChIP K-562 ENCSR360HRA.KDM1A.K-562 223 bp overlap
ChIP K-562 ENCSR908CMW.KDM1A.K-562 212 bp overlap
ChIP K-562_Wnt GSE117944.KDM1A.K-562_Wnt 222 bp overlap
ChIP K562 ENCFF133OLU 279 bp overlap
KLF16 1 dataset
ChIP K-562 ENCSR760UVO.KLF16.K-562 121 bp overlap
LDB1 2 datasets
ChIP HEP GSE52637.LDB1.HEP 226 bp overlap
ChIP K-562 GSE142227.LDB1.K-562 279 bp overlap
MAFG 1 dataset
ChIP K-562 ENCSR818DQV.MAFG.K-562 263 bp overlap
MECOM 1 dataset
ChIP K562 ENCFF773RGL 279 bp overlap
MED12 2 datasets
ChIP leiomyoma_PT1063 GSE128230.MED12.leiomyoma_PT1063 73 bp overlap
ChIP leiomyoma_PT886 GSE128230.MED12.leiomyoma_PT886 66 bp overlap
MEIS1 1 dataset
ChIP CHRF28811 ERR063469.MEIS1.CHRF28811 279 bp overlap
MEIS2 1 dataset
ChIP K-562 ENCSR851BNE.MEIS2.K-562 279 bp overlap
MTA2 2 datasets
ChIP K-562 ENCSR113LAS.MTA2.K-562 191 bp overlap
ChIP K562 ENCFF880VZB 222 bp overlap
MXI1 1 dataset
ChIP SK-N-SH ENCSR000EIA.MXI1.SK-N-SH 226 bp overlap
MYC 2 datasets
ChIP K-562 ENCSR000EZU.MYC.K-562 190 bp overlap
ChIP K-562 ENCSR000EGS.MYC.K-562 213 bp overlap
MYCN 2 datasets
ChIP Kelly GSE94822.MYCN.Kelly 201 bp overlap
ChIP LA-N-5 GSE138295.MYCN.LA-N-5 178 bp overlap
NBN 1 dataset
ChIP K-562 ENCSR085QEV.NBN.K-562 225 bp overlap
NCOR1 4 datasets
ChIP K-562 ENCSR910JAI.NCOR1.K-562 228 bp overlap
ChIP K-562 ENCSR798ILC.NCOR1.K-562 279 bp overlap
ChIP K562 ENCFF788MPU 169 bp overlap
ChIP K562 ENCFF866HRM 209 bp overlap
NFE2 1 dataset
ChIP ProEs GSE59087.NFE2.ProEs 207 bp overlap
NFIC 2 datasets
ChIP K-562 ENCSR796ITY.NFIC.K-562 205 bp overlap
ChIP K562 ENCFF167YID 279 bp overlap
NKX2-5 2 datasets
ChIP hESC_ab3584 GSE89457.NKX2-5.hESC_ab3584 267 bp overlap
ChIP hESC_sc-14033 GSE89457.NKX2-5.hESC_sc-14033 145 bp overlap
NR2F2 1 dataset
ChIP K-562 ENCSR000BRS.NR2F2.K-562 222 bp overlap
NR3C1 2 datasets
ChIP A-549 ENCSR000BHF.NR3C1.A-549 129 bp overlap
ChIP K-562_GLUCC ERP007081.NR3C1.K-562_GLUCC 168 bp overlap
PBX2 1 dataset
ChIP K-562 ENCSR263DFP.PBX2.K-562 255 bp overlap
PHIP 1 dataset
ChIP HEK293_ab833 GSE101646.PHIP.HEK293_ab833 279 bp overlap
PITX3 1 dataset
ChIP SH-SY5Y GSE93275.PITX3.SH-SY5Y 279 bp overlap
PKNOX1 1 dataset
ChIP K-562 ENCSR115SMW.PKNOX1.K-562 279 bp overlap
PML 1 dataset
ChIP K-562 ENCSR000BQY.PML.K-562 208 bp overlap
RAD21 1 dataset
ChIP SK-N-SH ENCSR000EHX.RAD21.SK-N-SH 164 bp overlap
RCOR1 2 datasets
ChIP K562 ENCFF216EEJ 265 bp overlap
ChIP SK-N-SH ENCSR009TKN.RCOR1.SK-N-SH 232 bp overlap
RFX5 1 dataset
ChIP SK-N-SH ENCSR000EHY.RFX5.SK-N-SH 222 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 279 bp overlap
SMAD2_3 1 dataset
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 166 bp overlap
SMARCA4 4 datasets
ChIP K-562 ENCSR643VTW.SMARCA4.K-562 256 bp overlap
ChIP K-562 ENCSR587OQL.SMARCA4.K-562 279 bp overlap
ChIP K562 ENCFF316MCJ 279 bp overlap
ChIP K562 ENCFF506JCB 214 bp overlap
SMARCE1 3 datasets
ChIP K-562 ENCSR157TCS.SMARCE1.K-562 279 bp overlap
ChIP K562 ENCFF690CFF 279 bp overlap
ChIP K562 ENCFF690CFF 83 bp overlap
SMC1A 1 dataset
ChIP LCL GSE38395.SMC1A.LCL 98 bp overlap
SOX6 2 datasets
ChIP K-562 ENCSR788RSW.SOX6.K-562 279 bp overlap
ChIP K562 ENCFF059YCJ 180 bp overlap
SPI1 2 datasets
ChIP K-562 ENCSR000BGW.SPI1.K-562 146 bp overlap
ChIP K-562 GSE70482.SPI1.K-562 173 bp overlap
STAT1 3 datasets
ChIP K-562 ENCSR000EHJ.STAT1.K-562 149 bp overlap
ChIP K-562 ENCSR000EHK.STAT1.K-562 124 bp overlap
ChIP SET-2_DMSO GSE100566.STAT1.SET-2_DMSO 175 bp overlap
STAT5A 3 datasets
ChIP K-562 ENCSR000BRR.STAT5A.K-562 279 bp overlap
ChIP K562 ENCFF226BTJ 226 bp overlap
ChIP K562 ENCFF226BTJ 194 bp overlap
TAL1 15 datasets
ChIP CD34 GSE52924.TAL1.CD34 245 bp overlap
ChIP CHRF28811 ERP008568.TAL1.CHRF28811 279 bp overlap
ChIP HSPC-CD34pos GSE93372.TAL1.HSPC-CD34pos 230 bp overlap
ChIP K-562 GSE107726.TAL1.K-562 279 bp overlap
ChIP K-562 ENCSR106FRG.TAL1.K-562 279 bp overlap
ChIP K-562 ENCSR000EHB.TAL1.K-562 279 bp overlap
ChIP K-562_dCas9-KRAB GSE132212.TAL1.K-562_dCas9-KRAB 279 bp overlap
ChIP K-562_dCas9-LSD1 GSE132212.TAL1.K-562_dCas9-LSD1 266 bp overlap
ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 277 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 277 bp overlap
ChIP K-562_sgGal4 GSE132212.TAL1.K-562_sgGal4 240 bp overlap
ChIP K562 ENCFF620GMX 266 bp overlap
ChIP K562 ENCFF661CCK 76 bp overlap
ChIP ProEs GSE59087.TAL1.ProEs 266 bp overlap
ChIP erythroid GSE42390.TAL1.erythroid 230 bp overlap
TBL1XR1 2 datasets
ChIP K-562 ENCSR000EGB.TBL1XR1.K-562 143 bp overlap
ChIP K562 ENCFF899VEC 279 bp overlap
TBX5 1 dataset
ChIP hiPSC GSE81585.TBX5.hiPSC 253 bp overlap
TCF12 4 datasets
ChIP K-562 ENCSR744WOO.TCF12.K-562 279 bp overlap
ChIP K-562 ENCSR189TRZ.TCF12.K-562 267 bp overlap
ChIP K562 ENCFF909RDY 279 bp overlap
ChIP K562 ENCFF931DJY 230 bp overlap
TCF3 2 datasets
ChIP K-562 ENCSR970OJY.TCF3.K-562 265 bp overlap
ChIP K562 ENCFF319QZT 279 bp overlap
TCF4 2 datasets
ChIP SH-SY5Y GSE96915.TCF4.SH-SY5Y 206 bp overlap
ChIP SK-N-SH ENCFF270OWF 279 bp overlap
TEAD4 1 dataset
ChIP K562 ENCFF673NIK 181 bp overlap
TRIM28 2 datasets
ChIP K-562 ENCSR000BRW.TRIM28.K-562 272 bp overlap
ChIP K562 ENCFF172UPN 232 bp overlap
TSHZ2 1 dataset
ChIP SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour ENCSR282NLQ.TSHZ2.SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour 167 bp overlap
TWIST1 2 datasets
ChIP BE2C GSE80151.TWIST1.BE2C 173 bp overlap
ChIP SK-N-BE2-C GSE80151.TWIST1.SK-N-BE2-C 173 bp overlap
UBTF 1 dataset
ChIP K-562 ENCSR000EFZ.UBTF.K-562 167 bp overlap
YY1 2 datasets
ChIP Hep-G2_RBM25-KD GSE120104.YY1.Hep-G2_RBM25-KD 247 bp overlap
ChIP K-562 ENCSR000BMH.YY1.K-562 110 bp overlap
ZBTB17 1 dataset
ChIP HEK293 ENCFF865LIO 242 bp overlap
ZBTB7A 1 dataset
ChIP HUDEP-2 GSE103445.ZBTB7A.HUDEP-2 279 bp overlap
ZEB2 4 datasets
ChIP K-562 ENCSR004GKA.ZEB2.K-562 279 bp overlap
ChIP K-562 ENCSR322CFO.ZEB2.K-562 279 bp overlap
ChIP K562 ENCFF795CMH 279 bp overlap
ChIP K562 ENCFF975RXS 279 bp overlap
ZFP36 1 dataset
ChIP K-562 ENCSR776CYN.ZFP36.K-562 105 bp overlap
ZNF213 1 dataset
Motif DE_60h DE_60h-ZNF213_MA2121.1 12 bp overlap
ZNF281 1 dataset
ChIP K562 ENCFF594VNM 279 bp overlap
ZNF416 1 dataset
Motif DE_60h DE_60h-ZNF416_MA1979.2 10 bp overlap
ZSCAN16 2 datasets
ChIP HEK293 ENCFF533NFT 262 bp overlap
ChIP HEK293 ENCSR864VJE.ZSCAN16.HEK293 272 bp overlap
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