chr22:31,127,262–31,127,766

chr22 : 31,127,262 – 31,127,766

504 bp 74 TFs 10 linked genes

This 504 bp open chromatin element is linked to 10 target genes and is bound by 74 transcription factors.

Linked Genes

10 genes

Gene	Expression	Dist. to TSS	Distance	Link type
INPP5J		4.3 kb	Proximal	Proximity
PLA2G3		13.0 kb	Distal	Multiome
SELENOM		20.0 kb	Distal	Multiome
RNF185		32.6 kb	Distal	Multiome
SMTN		46.2 kb	Distal	Multiome
LIMK2		84.7 kb	Distal	Multiome
TUG1		158.3 kb	Distal	Multiome
MORC2		158.8 kb	Distal	Multiome
PATZ1		218.8 kb	Distal	Multiome
DRG1		272.1 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

74 transcription factors

ChIP K-562 ENCSR972ZBV.ATF7.K-562 384 bp overlap

BCL6 3 datasets

ChIP OCI-Ly1 GSE29282.BCL6.OCI-Ly1 184 bp overlap

ChIP OCI-Ly1 GSE29282.BCL6.OCI-Ly1 152 bp overlap

ChIP SU-DHL-4 GSE119038.BCL6.SU-DHL-4 429 bp overlap

ChIP WA01 GSE104690.BCOR.WA01 172 bp overlap

BHLHE40 1 dataset

ChIP K-562 ENCSR000EGV.BHLHE40.K-562 170 bp overlap

ChIP K-562_DMSO GSE138084.BRD2.K-562_DMSO 91 bp overlap

BRD4 4 datasets

ChIP 402-91 GSE111253.BRD4.402-91 212 bp overlap

ChIP IMR-90_QUIES GSE74238.BRD4.IMR-90_QUIES 141 bp overlap

ChIP K-562_iBET-BD2 GSE138084.BRD4.K-562_iBET-BD2 102 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 221 bp overlap

CREB1 1 dataset

ChIP WA01 ENCSR000BSN.CREB1.WA01 119 bp overlap

CTBP1 2 datasets

ChIP K-562 ENCSR201NQZ.CTBP1.K-562 225 bp overlap

ChIP K-562 ENCSR201NQZ.CTBP1.K-562 159 bp overlap

E2F6 4 datasets

ChIP H1 ENCFF785DWK 337 bp overlap

ChIP K-562 ENCSR000EWJ.E2F6.K-562 287 bp overlap

ChIP K-562 ENCSR000BLI.E2F6.K-562 95 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 189 bp overlap

E4F1 2 datasets

ChIP K-562 ENCSR731LHZ.E4F1.K-562 59 bp overlap

ChIP K562 ENCFF622HMZ 198 bp overlap

EGR1 6 datasets

ChIP K-562 ENCSR211LTF.EGR1.K-562 201 bp overlap

ChIP K-562 ENCSR024CNP.EGR1.K-562 145 bp overlap

ChIP K-562 ENCSR000BNE.EGR1.K-562 147 bp overlap

ChIP K562 ENCFF006PJY 137 bp overlap

ChIP K562 ENCFF113OPQ 241 bp overlap

ChIP K562 ENCFF895KGN 53 bp overlap

ChIP HEK293 ENCFF336LFH 91 bp overlap

ChIP AMLPZ12 GSE23730.ERG.AMLPZ12 196 bp overlap

ChIP SKNO-1 GSE23730.ERG.SKNO-1 264 bp overlap

ChIP Ishikawa_DMSO_D538G_clone3 GSE132426.ESR1.Ishikawa_DMSO_D538G_clone3 228 bp overlap

ESRRA 1 dataset

ChIP SK-BR-3_HRG GSE81651.ESRRA.SK-BR-3_HRG 284 bp overlap

ChIP SKNO-1 GSE23730.FLI1.SKNO-1 268 bp overlap

FOXK2 1 dataset

ChIP K-562 ENCSR508DQA.FOXK2.K-562 285 bp overlap

GLIS2 1 dataset

ChIP HEK293 ENCSR535DIA.GLIS2.HEK293 225 bp overlap

HAND2 1 dataset

ChIP SK-N-BE2-C GSE94822.HAND2.SK-N-BE2-C 504 bp overlap

HDAC1 2 datasets

ChIP K-562_dilution-6-100 GSE140325.HDAC1.K-562_dilution-6-100 175 bp overlap

ChIP K-562_dilution-6-100 GSE140325.HDAC1.K-562_dilution-6-100 84 bp overlap

HDAC2 1 dataset

ChIP K-562 ENCSR075HTM.HDAC2.K-562 162 bp overlap

HDGF 2 datasets

ChIP K-562 ENCSR197ALX.HDGF.K-562 440 bp overlap

ChIP K-562 ENCSR563YDA.HDGF.K-562 410 bp overlap

IFNA1 1 dataset

ChIP Huh-7_GFP GSE110511.IFNA1.Huh-7_GFP 177 bp overlap

IKZF1 2 datasets

ChIP K-562 ENCSR395HWC.IKZF1.K-562 289 bp overlap

ChIP K562 ENCFF771OHZ 392 bp overlap

INTS11 1 dataset

ChIP HL-60 GSE106359.INTS11.HL-60 399 bp overlap

INTS13 3 datasets

ChIP HL-60 GSE106359.INTS13.HL-60 282 bp overlap

ChIP HL-60_PMA GSE106359.INTS13.HL-60_PMA 268 bp overlap

ChIP HL-60_shEGR1 GSE106359.INTS13.HL-60_shEGR1 431 bp overlap

KDM5B 1 dataset

ChIP SUM185_SHCTCF GSE46055.KDM5B.SUM185_SHCTCF 114 bp overlap

KLF1 3 datasets

ChIP HEK293 ENCFF159QSW 504 bp overlap

ChIP HEK293 ENCSR859BMR.KLF1.HEK293 504 bp overlap

ChIP HEK293 GSE76494.KLF1.HEK293 504 bp overlap

KLF4 3 datasets

ChIP BJ_INDUCED GSE36570.KLF4.BJ_INDUCED 186 bp overlap

ChIP BJ_INDUCED GSE36570.KLF4.BJ_INDUCED 254 bp overlap

ChIP HAP1 GSE130417.KLF4.HAP1 238 bp overlap

KLF8 2 datasets

ChIP HEK293 ENCFF929IAJ 321 bp overlap

ChIP HEK293 ENCSR635NOQ.KLF8.HEK293 207 bp overlap

L3MBTL2 1 dataset

ChIP K-562 ENCSR530XQI.L3MBTL2.K-562 226 bp overlap

MAX 11 datasets

ChIP H1 ENCFF914VQY 206 bp overlap

ChIP K-562 ENCSR000EFV.MAX.K-562 190 bp overlap

ChIP K562 ENCFF398VJM 386 bp overlap

ChIP K562 ENCFF524IJO 131 bp overlap

ChIP NCI-H2171 GSE41105.MAX.NCI-H2171 343 bp overlap

ChIP NCI-H2171 GSE36354.MAX.NCI-H2171 383 bp overlap

ChIP P493-6 GSE36354.MAX.P493-6 318 bp overlap

ChIP P493-6 GSE42262.MAX.P493-6 424 bp overlap

ChIP P493-6_24HR GSE125863.MAX.P493-6_24HR 147 bp overlap

ChIP P493-6_24HR GSE125863.MAX.P493-6_24HR 139 bp overlap

ChIP P493-6_CMYC_1H GSE36354.MAX.P493-6_CMYC_1H 278 bp overlap

ChIP K-562 ENCSR000EFX.MAZ.K-562 117 bp overlap

ChIP THP-1_OG86 GSE90769.MYB.THP-1_OG86 177 bp overlap

ChIP BJ_INDUCED GSE36570.MYC.BJ_INDUCED 220 bp overlap

ChIP K-562 ENCSR000EGJ.MYC.K-562 213 bp overlap

ChIP K-562 ENCSR000FAG.MYC.K-562 124 bp overlap

ChIP NCI-H2171 GSE36354.MYC.NCI-H2171 391 bp overlap

ChIP P493-6 GSE77061.MYC.P493-6 243 bp overlap

ChIP P493-6_Dpy30-shRNA GSE101853.MYC.P493-6_Dpy30-shRNA 163 bp overlap

ChIP P493-6_MST-312 GSE77061.MYC.P493-6_MST-312 168 bp overlap

ChIP P493-6_SHTERC GSE60223.MYC.P493-6_SHTERC 218 bp overlap

ChIP P493-6_scramble-shRNA GSE101853.MYC.P493-6_scramble-shRNA 368 bp overlap

MYCN 5 datasets

ChIP BE2C GSE80151.MYCN.BE2C 414 bp overlap

ChIP Kelly GSE94782.MYCN.Kelly 231 bp overlap

ChIP Kelly_sensitive GSE115249.MYCN.Kelly_sensitive 232 bp overlap

ChIP SK-N-BE2-C GSE80151.MYCN.SK-N-BE2-C 411 bp overlap

ChIP SK-N-BE2-C GSE94822.MYCN.SK-N-BE2-C 217 bp overlap

ChIP K-562 ENCSR737LTZ.MYNN.K-562 151 bp overlap

MYOD1 1 dataset

ChIP IMR-90_GM GSE128527.MYOD1.IMR-90_GM 227 bp overlap

NELFA 1 dataset

ChIP K-562_HS GSE112379.NELFA.K-562_HS 121 bp overlap

NELFE 4 datasets

ChIP K-562_HS GSE112379.NELFE.K-562_HS 162 bp overlap

ChIP K-562_HS GSE112379.NELFE.K-562_HS 165 bp overlap

ChIP K-562_NHS GSE112379.NELFE.K-562_NHS 280 bp overlap

ChIP K-562_NHS GSE112379.NELFE.K-562_NHS 101 bp overlap

NR2F1 1 dataset

ChIP K-562 ENCSR970NKQ.NR2F1.K-562 68 bp overlap

NRF1 9 datasets

ChIP K-562 ENCSR998AJK.NRF1.K-562 421 bp overlap

ChIP K-562 ENCSR494TDU.NRF1.K-562 420 bp overlap

ChIP K-562 ENCSR837EYC.NRF1.K-562 280 bp overlap

ChIP K-562_Ab_R157-1-3D4 GSE97661.NRF1.K-562_Ab_R157-1-3D4 305 bp overlap

ChIP K-562_Ab_R157-1-3H1 GSE97661.NRF1.K-562_Ab_R157-1-3H1 156 bp overlap

ChIP K-562_Ab_R157-1-3H3 GSE97661.NRF1.K-562_Ab_R157-1-3H3 281 bp overlap

ChIP K562 ENCFF130SGK 263 bp overlap

ChIP K562 ENCFF689EWI 391 bp overlap

ChIP K562 ENCFF791UHF 359 bp overlap

PCBP1 1 dataset

ChIP Hep-G2 GSE120104.PCBP1.Hep-G2 201 bp overlap

ChIP K-562 ENCSR000AQH.PHF8.K-562 217 bp overlap

PLAG1 1 dataset

ChIP K-562 GSE111469.PLAG1.K-562 149 bp overlap

POLR2A 2 datasets

ChIP GM23338 ENCFF450WCS 491 bp overlap

ChIP GM23338 ENCFF450WCS 200 bp overlap

POU5F1 3 datasets

ChIP BG03 GSE21614.POU5F1.BG03 202 bp overlap

ChIP SKM-1 GSE93706.POU5F1.SKM-1 252 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 353 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 248 bp overlap

RAD21 1 dataset

ChIP hiPSC_IV8 GSE106870.RAD21.hiPSC_IV8 153 bp overlap

RBFOX2 4 datasets

ChIP K-562 ENCSR822LBD.RBFOX2.K-562 213 bp overlap

ChIP K-562 GSE120104.RBFOX2.K-562 195 bp overlap

ChIP K-562 GSE120104.RBFOX2.K-562 121 bp overlap

ChIP K-562 ENCSR822LBD.RBFOX2.K-562 113 bp overlap

ChIP K-562 ENCSR000BMW.REST.K-562 112 bp overlap

RUNX1 2 datasets

ChIP AML_Blast GSE60130.RUNX1.AML_Blast 157 bp overlap

ChIP CD34 GSE64862.RUNX1.CD34 157 bp overlap

ChIP WA01 GSE104690.RYBP.WA01 260 bp overlap

SCRT2 1 dataset

ChIP HEK293 ENCFF711QQB 143 bp overlap

SIRT6 1 dataset

ChIP SK-MEL-239_L-C-B GSE102813.SIRT6.SK-MEL-239_L-C-B 159 bp overlap

SMARCA4 1 dataset

ChIP K-562 ENCSR587OQL.SMARCA4.K-562 260 bp overlap

SMARCB1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 340 bp overlap

ChIP HEK293 GSE76494.SP1.HEK293 112 bp overlap

ChIP HEK293 GSE76494.SP1.HEK293 148 bp overlap

ChIP HEK293 ENCFF181QXT 141 bp overlap

ChIP HEK293 ENCSR807LQP.SP2.HEK293 181 bp overlap

ChIP HEK293 GSE76494.SP2.HEK293 198 bp overlap

ChIP HEK293 ENCSR807LQP.SP2.HEK293 192 bp overlap

ChIP HEK293 GSE76494.SP4.HEK293 504 bp overlap

SREBP2 1 dataset

ChIP monocyte GSE129202.SREBP2.monocyte 504 bp overlap

STAT3 1 dataset

ChIP monocyte_IFNg-LPS GSE120943.STAT3.monocyte_IFNg-LPS 159 bp overlap

ChIP K-562 ENCSR000BKS.TAF1.K-562 164 bp overlap

ChIP K-562 GSE55306.TBP.K-562 182 bp overlap

TRIM28 1 dataset

ChIP WIBR3_NAIVE GSE84382.TRIM28.WIBR3_NAIVE 164 bp overlap

TWIST1 2 datasets

ChIP BE2C GSE80151.TWIST1.BE2C 422 bp overlap

ChIP SK-N-BE2-C GSE80151.TWIST1.SK-N-BE2-C 422 bp overlap

ChIP Huh-7 GSE97411.YY1.Huh-7 204 bp overlap

ZBTB33 2 datasets

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 352 bp overlap

ChIP K562 ENCFF875HLX 263 bp overlap

ZBTB7A 1 dataset

ChIP K-562 ENCSR000BME.ZBTB7A.K-562 93 bp overlap

ZFHX2 1 dataset

ChIP HEK293 ENCFF167TUA 174 bp overlap

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 98 bp overlap

ZNF148 1 dataset

ChIP K562 ENCFF352SDL 167 bp overlap

ZNF281 2 datasets

ChIP K-562 GSE121133.ZNF281.K-562 190 bp overlap

ChIP K562 ENCFF594VNM 130 bp overlap

ZNF300 1 dataset

ChIP HEK293T GSE78099.ZNF300.HEK293T 296 bp overlap