chr17:19,460,682–19,461,395

chr17 : 19,460,682 – 19,461,395

713 bp 93 TFs 7 linked genes

This 713 bp open chromatin element is linked to 7 target genes and is bound by 93 transcription factors.

Linked Genes

7 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000235979		4.9 kb	Proximal	Multiome
SLC47A1		72.6 kb	Distal	Multiome
MFAP4		74.0 kb	Distal	Multiome
MAPK7		83.5 kb	Distal	Multiome
B9D1		98.2 kb	Distal	Multiome
ALDH3A2		187.6 kb	Distal	Multiome+HiCAR
EPN2		223.7 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

93 transcription factors

ChIP prostate_1816_T GSE130408.AR.prostate_1816_T 163 bp overlap

ARID1A 1 dataset

ChIP HAP1 GSE108387.ARID1A.HAP1 314 bp overlap

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 288 bp overlap

ATF2 2 datasets

ChIP WA01 ENCSR000BQU.ATF2.WA01 180 bp overlap

ChIP WA01 ENCSR000BQU.ATF2.WA01 146 bp overlap

BCL6 3 datasets

ChIP OCI-Ly1 GSE29282.BCL6.OCI-Ly1 255 bp overlap

ChIP OCI-Ly1 GSE29282.BCL6.OCI-Ly1 86 bp overlap

ChIP SU-DHL-4 GSE119038.BCL6.SU-DHL-4 114 bp overlap

ChIP H-1_DE GSE126661.BRD3.H-1_DE 216 bp overlap

BRD4 14 datasets

ChIP HAP1 GSE108387.BRD4.HAP1 312 bp overlap

ChIP MM1-S_JQ1_500NM GSE42355.BRD4.MM1-S_JQ1_500NM 172 bp overlap

ChIP MM1-S_JQ1_5NM GSE42355.BRD4.MM1-S_JQ1_5NM 184 bp overlap

ChIP MM1-S_JQ1_5NM GSE42355.BRD4.MM1-S_JQ1_5NM 207 bp overlap

ChIP Mutu-1_vehicle GSE84213.BRD4.Mutu-1_vehicle 203 bp overlap

ChIP RH4_shCHD4 GSE140115.BRD4.RH4_shCHD4 268 bp overlap

ChIP RH4_shCHD4 GSE140115.BRD4.RH4_shCHD4 177 bp overlap

ChIP cortical-interneuron GSE117508.BRD4.cortical-interneuron 285 bp overlap

ChIP cortical-interneuron_KCl-pos GSE117508.BRD4.cortical-interneuron_KCl-pos 193 bp overlap

ChIP cortical-interneuron_R133C_KCl-neg_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-neg_JQ1-neg 375 bp overlap

ChIP cortical-interneuron_R133C_KCl-neg_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-neg_JQ1-neg 211 bp overlap

ChIP cortical-interneuron_R133C_KCl-neg_JQ1-pos GSE117508.BRD4.cortical-interneuron_R133C_KCl-neg_JQ1-pos 124 bp overlap

ChIP cortical-interneuron_R133C_KCl-pos_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-pos_JQ1-neg 213 bp overlap

ChIP hESC GSE33281.BRD4.hESC 87 bp overlap

CBFA2T3 1 dataset

ChIP U-937 GSE126953.CBFA2T3.U-937 215 bp overlap

ChIP myometrium_PT916 GSE128230.CDK8.myometrium_PT916 116 bp overlap

ChIP MM1-S_DMSO GSE42355.CDK9.MM1-S_DMSO 236 bp overlap

CDX1 2 datasets

Motif DE_12h DE_12h-CDX1_MA0878.3 10 bp overlap

Motif DE_48h DE_48h-CDX1_MA0878.3 10 bp overlap

CDX4 2 datasets

Motif DE_12h DE_12h-CDX4_MA1473.2 9 bp overlap

Motif DE_48h DE_48h-CDX4_MA1473.2 9 bp overlap

ChIP H1 ENCFF126NLU 552 bp overlap

CREB1 2 datasets

ChIP LNCaP-abl_SHFOXA1 GSE63034.CREB1.LNCaP-abl_SHFOXA1 227 bp overlap

ChIP MCF-7 ENCSR620DUQ.CREB1.MCF-7 267 bp overlap

CTBP2 1 dataset

ChIP WA01 ENCSR000EUO.CTBP2.WA01 122 bp overlap

CTCF 13 datasets

ChIP HAP1_clone21_CTCF-CRISPR GSE152721.CTCF.HAP1_clone21_CTCF-CRISPR 292 bp overlap

ChIP HAP1_clone21_CTCF-TSS-CRISPR_1 GSE152721.CTCF.HAP1_clone21_CTCF-TSS-CRISPR_1 240 bp overlap

ChIP HAP1_clone21_TSS-CRISPR GSE152721.CTCF.HAP1_clone21_TSS-CRISPR 270 bp overlap

ChIP KARPAS422 ENCSR113REG.CTCF.KARPAS422 184 bp overlap

ChIP RH4 GSE83726.CTCF.RH4 219 bp overlap

ChIP anterior-temporal-cortex_fetal GSE116825.CTCF.anterior-temporal-cortex_fetal 157 bp overlap

ChIP dorsolateral prefrontal cortex ENCFF458OBF 511 bp overlap

ChIP dorsolateral prefrontal cortex ENCFF458OBF 467 bp overlap

ChIP dorsolateral prefrontal cortex ENCFF748IBN 517 bp overlap

ChIP dorsolateral prefrontal cortex ENCFF835ZSJ 536 bp overlap

ChIP hiPSC_IID12 GSE106870.CTCF.hiPSC_IID12 145 bp overlap

ChIP hiPSC_failed-genome-editing GSE106870.CTCF.hiPSC_failed-genome-editing 151 bp overlap

ChIP primary-glioblastoma_G523 GSE121601.CTCF.primary-glioblastoma_G523 295 bp overlap

CTNNB1 1 dataset

ChIP hESC_YAP-_activinA_15h GSE99202.CTNNB1.hESC_YAP-_activinA_15h 380 bp overlap

ChIP GM12878 ENCSR509FWH.DPF2.GM12878 59 bp overlap

EBF1 2 datasets

ChIP MUTUL GSE75503.EBF1.MUTUL 365 bp overlap

ChIP NALM-6 GSE126300.EBF1.NALM-6 186 bp overlap

ChIP HEK293 ENCFF336LFH 425 bp overlap

EOMES 2 datasets

ChIP hESC GSE26097.EOMES.hESC 182 bp overlap

ChIP hESC GSE26097.EOMES.hESC 177 bp overlap

ChIP MM.1S ENCFF966SYG 446 bp overlap

FEZF2 2 datasets

Motif DE_12h DE_12h-FEZF2_MA2341.1 8 bp overlap

Motif DE_48h DE_48h-FEZF2_MA2341.1 8 bp overlap

FOXA2 1 dataset

ChIP DE DE-FOXA2-2 210 bp overlap

FOXO1-PAX3 2 datasets

ChIP RH4_DMSO-6H GSE116344.FOXO1-PAX3.RH4_DMSO-6H 324 bp overlap

ChIP RH4_Entinostat-6H GSE116344.FOXO1-PAX3.RH4_Entinostat-6H 251 bp overlap

GATA6 7 datasets

ChIP DE DE-GATA6-1 289 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 671 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 425 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 713 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 368 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 713 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 688 bp overlap

HOXB13 2 datasets

Motif DE_12h DE_12h-HOXB13_MA0901.3 9 bp overlap

Motif DE_48h DE_48h-HOXB13_MA0901.3 9 bp overlap

Hoxa13 2 datasets

Motif DE_12h DE_12h-Hoxa13_MA0650.4 8 bp overlap

Motif DE_48h DE_48h-Hoxa13_MA0650.4 8 bp overlap

IKZF2 1 dataset

ChIP GM12878 ENCSR822AHX.IKZF2.GM12878 202 bp overlap

IRF2BP2 1 dataset

ChIP HEK293 GSE124636.IRF2BP2.HEK293 272 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 368 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 629 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 622 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 325 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 691 bp overlap

ChIP HAEC GSE89970.JUNB.HAEC 153 bp overlap

KDM1A 1 dataset

ChIP H1 ENCFF696SGD 505 bp overlap

KLF9 2 datasets

ChIP GBM1A GSE62211.KLF9.GBM1A 94 bp overlap

ChIP GBM1A GSE62211.KLF9.GBM1A 117 bp overlap

MED1 3 datasets

ChIP MM1-S_JQ1_5000NM GSE49224.MED1.MM1-S_JQ1_5000NM 94 bp overlap

ChIP MM1-S_JQ1_50NM GSE49224.MED1.MM1-S_JQ1_50NM 209 bp overlap

ChIP MM1-S_JQ1_5NM GSE49224.MED1.MM1-S_JQ1_5NM 179 bp overlap

MED12 1 dataset

ChIP myometrium_PT916 GSE128230.MED12.myometrium_PT916 83 bp overlap

MEF2B 1 dataset

ChIP KARPAS422 GSE69558.MEF2B.KARPAS422 206 bp overlap

MORC2 1 dataset

ChIP H9 GSE95374.MORC2.H9 241 bp overlap

MTA2 2 datasets

ChIP GM12878 ENCSR293QAR.MTA2.GM12878 450 bp overlap

ChIP RH4 GSE155861.MTA2.RH4 606 bp overlap

ChIP Jurkat GSE59657.MYB.Jurkat 363 bp overlap

ChIP MOLT-3 GSE59657.MYB.MOLT-3 530 bp overlap

ChIP PF-382 GSE94000.MYB.PF-382 289 bp overlap

ChIP MM1-S_DMSO GSE36354.MYC.MM1-S_DMSO 260 bp overlap

MYOD1 1 dataset

ChIP RH4 GSE83726.MYOD1.RH4 214 bp overlap

NANOG 9 datasets

ChIP GM23338 ENCFF065NZG 311 bp overlap

ChIP GM23338 ENCSR061DGF.NANOG.GM23338 210 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 654 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 437 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 170 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 713 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 713 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 507 bp overlap

ChIP hESC GSE18292.NANOG.hESC 161 bp overlap

NFIC 4 datasets

ChIP Ishikawa ENCFF029AAD 381 bp overlap

ChIP Ishikawa ENCFF029AAD 349 bp overlap

ChIP Ishikawa ENCSR000BUT.NFIC.Ishikawa 203 bp overlap

ChIP Ishikawa ENCSR000BUT.NFIC.Ishikawa 122 bp overlap

NIPBL 2 datasets

ChIP hESC_WNT3A GSE64758.NIPBL.hESC_WNT3A 207 bp overlap

ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 237 bp overlap

NOTCH1 1 dataset

ChIP HPBALL GSE39263.NOTCH1.HPBALL 195 bp overlap

NR3C1 1 dataset

ChIP Ishikawa ENCSR000BJC.NR3C1.Ishikawa 101 bp overlap

OLIG2 4 datasets

ChIP brain-prefrontal-cortex_2016018 GSE129039.OLIG2.brain-prefrontal-cortex_2016018 286 bp overlap

ChIP brain-prefrontal-cortex_2017011 GSE129039.OLIG2.brain-prefrontal-cortex_2017011 462 bp overlap

ChIP brain-prefrontal-cortex_2017014 GSE129039.OLIG2.brain-prefrontal-cortex_2017014 257 bp overlap

ChIP brain-prefrontal-cortex_2018006 GSE129039.OLIG2.brain-prefrontal-cortex_2018006 82 bp overlap

PAX3-FOXO1 1 dataset

ChIP RH4 GSE140115.PAX3-FOXO1.RH4 280 bp overlap

ChIP NALM-6 GSE126300.PAX5.NALM-6 129 bp overlap

ChIP myometrium_NP1 GSE137550.PGR.myometrium_NP1 385 bp overlap

ChIP myometrium_NP2 GSE137550.PGR.myometrium_NP2 272 bp overlap

POU2F3 1 dataset

ChIP NCI-H1048 GSE115123.POU2F3.NCI-H1048 223 bp overlap

POU5F1 10 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 653 bp overlap

ChIP GM23338 ENCFF333SNB 311 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 682 bp overlap

ChIP NCCIT GSE36134.POU5F1.NCCIT 304 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 603 bp overlap

ChIP WA09_heat-shock GSE105028.POU5F1.WA09_heat-shock 223 bp overlap

ChIP hESC ENCSR264RJX.POU5F1.hESC 151 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 406 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 577 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 242 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 563 bp overlap

ChIP hiPSC_D3 GSE109172.RARA.hiPSC_D3 183 bp overlap

ChIP GSC8-11_12d-das GSE74557.RBPJ.GSC8-11_12d-das 264 bp overlap

RELA 6 datasets

ChIP aortic-endothelial-cell_IL1B_D13 GSE139377.RELA.aortic-endothelial-cell_IL1B_D13 422 bp overlap

ChIP aortic-endothelial-cell_IL1B_D26 GSE139377.RELA.aortic-endothelial-cell_IL1B_D26 314 bp overlap

ChIP aortic-endothelial-cell_IL1B_D4 GSE139377.RELA.aortic-endothelial-cell_IL1B_D4 195 bp overlap

ChIP aortic-endothelial-cell_IL1B_D41 GSE139377.RELA.aortic-endothelial-cell_IL1B_D41 183 bp overlap

ChIP aortic-endothelial-cell_IL1B_D53 GSE139377.RELA.aortic-endothelial-cell_IL1B_D53 147 bp overlap

ChIP aortic-endothelial-cell_IL1B_D7 GSE139377.RELA.aortic-endothelial-cell_IL1B_D7 167 bp overlap

RUNX1 1 dataset

ChIP NALM-6 GSE126300.RUNX1.NALM-6 180 bp overlap

ChIP macrophage ERP008801.RXR.macrophage 272 bp overlap

SMAD2 1 dataset

ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 611 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 713 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 713 bp overlap

SMAD2_3 6 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 713 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 713 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 713 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 713 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 170 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 367 bp overlap

SMAD3 1 dataset

ChIP BG03 GSE21614.SMAD3.BG03 149 bp overlap

SMARCA4 3 datasets

ChIP hiPSC GSE124903.SMARCA4.hiPSC 713 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 171 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 328 bp overlap

SMARCB1 3 datasets

ChIP hiPSC GSE124903.SMARCB1.hiPSC 287 bp overlap

ChIP hiPSC GSE124903.SMARCB1.hiPSC 159 bp overlap

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 226 bp overlap

SMARCC1 4 datasets

ChIP DE_D1 S10-DE-d1-BAF155-exp1 598 bp overlap

ChIP DE_D1 S15-DE-d1-BAF155-exp1 421 bp overlap

ChIP hiPSC GSE124903.SMARCC1.hiPSC 358 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 213 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 663 bp overlap

SOX2 4 datasets

ChIP H9 GSE46837.SOX2.H9 242 bp overlap

ChIP LK2 GSE137459.SOX2.LK2 307 bp overlap

ChIP LK2_GFP GSE137459.SOX2.LK2_GFP 442 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 346 bp overlap

ChIP RH4_DMSO-6H GSE116344.SOX8.RH4_DMSO-6H 189 bp overlap

ChIP H1 ENCFF263FUH 278 bp overlap

ChIP macrophage_D7_donorP GSE128834.SPI1.macrophage_D7_donorP 200 bp overlap

SREBP2 2 datasets

ChIP monocyte GSE129202.SREBP2.monocyte 199 bp overlap

ChIP monocyte_TNF GSE129202.SREBP2.monocyte_TNF 311 bp overlap

ChIP SYO-1 GSE108025.SS18.SYO-1 619 bp overlap

ChIP H1 ENCFF061XZZ 337 bp overlap

ChIP MOLT-3 GSE59657.TAL1.MOLT-3 283 bp overlap

ChIP hESC GSE122298.TBP.hESC 138 bp overlap

ChIP hESC_2h GSE122298.TBP.hESC_2h 150 bp overlap

TBX21 1 dataset

ChIP GM12878 ENCSR739IHN.TBX21.GM12878 320 bp overlap

TCF12 4 datasets

ChIP H1 ENCFF203EBH 251 bp overlap

ChIP Ishikawa ENCSR000BUV.TCF12.Ishikawa 200 bp overlap

ChIP Ishikawa ENCSR000BUV.TCF12.Ishikawa 290 bp overlap

ChIP WA01 ENCSR000BIT.TCF12.WA01 562 bp overlap

ChIP NPC GSE154479.TCF3.NPC 495 bp overlap

ChIP GEN2-2 GSE76147.TCF4.GEN2-2 105 bp overlap

TEAD4 1 dataset

ChIP Ishikawa ENCFF772OTG 301 bp overlap

ChIP H9_mesoderm GSE142050.TP53.H9_mesoderm 252 bp overlap

ChIP Ishikawa ENCSR000BSY.YY1.Ishikawa 92 bp overlap

ChIP RH4_DMSO-6H GSE116344.YY1.RH4_DMSO-6H 173 bp overlap

ZBTB17 1 dataset

ChIP HEK293 ENCFF865LIO 160 bp overlap

ZBTB48 1 dataset

ChIP HEK293 ENCSR781EQJ.ZBTB48.HEK293 232 bp overlap

ZNF24 2 datasets

Motif DE_12h DE_12h-ZNF24_MA1124.1 13 bp overlap

Motif DE_48h DE_48h-ZNF24_MA1124.1 13 bp overlap

ZNF429 1 dataset

ChIP HEK293T GSE78099.ZNF429.HEK293T 357 bp overlap

ZNF479 1 dataset

ChIP HEK293T GSE78099.ZNF479.HEK293T 166 bp overlap

ZNF534 1 dataset

ChIP HEK293T GSE78099.ZNF534.HEK293T 88 bp overlap

ZNF585B 2 datasets

ChIP HEK293 ENCFF657XIZ 122 bp overlap

ChIP HEK293 ENCSR011XCI.ZNF585B.HEK293 228 bp overlap

ZNF667 2 datasets

Motif DE_12h DE_12h-ZNF667_MA1984.2 11 bp overlap

Motif DE_48h DE_48h-ZNF667_MA1984.2 11 bp overlap

ZNF675 2 datasets

Motif DE_12h DE_12h-ZNF675_MA1714.2 19 bp overlap

Motif DE_48h DE_48h-ZNF675_MA1714.2 19 bp overlap

ZNF692 2 datasets

Motif DE_12h DE_12h-ZNF692_MA1986.2 8 bp overlap

Motif DE_48h DE_48h-ZNF692_MA1986.2 8 bp overlap