chr16 : 55,167,660 – 55,168,195
535 bp 147 TFs 1 linked gene
This 535 bp open chromatin element is linked to CRNDE and is bound by 147 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
CRNDE 238.8 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr16:55,162,660 – 55,173,195
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
147 transcription factors
Source
Cell type
ALX3 1 dataset
Motif DE_36h DE_36h-ALX3_MA0634.2 6 bp overlap
ARGFX 1 dataset
Motif DE_36h DE_36h-ARGFX_MA1463.2 8 bp overlap
Alx1 1 dataset
Motif DE_36h DE_36h-Alx1_MA0854.2 8 bp overlap
Alx4 1 dataset
Motif DE_36h DE_36h-Alx4_MA0853.2 12 bp overlap
Arx 1 dataset
Motif DE_36h DE_36h-Arx_MA0874.2 10 bp overlap
CTCF 2 datasets
Motif DE_36h DE_36h-CTCF_MA1929.2 31 bp overlap
Motif DE_36h DE_36h-CTCF_MA1930.2 33 bp overlap
DRGX 1 dataset
Motif DE_36h DE_36h-DRGX_MA1481.2 6 bp overlap
ELF1 1 dataset
Motif DE_36h DE_36h-ELF1_MA0473.4 9 bp overlap
ELF3 1 dataset
Motif DE_36h DE_36h-ELF3_MA0640.3 9 bp overlap
EMX1 1 dataset
Motif DE_36h DE_36h-EMX1_MA0612.3 6 bp overlap
EMX2 1 dataset
Motif DE_36h DE_36h-EMX2_MA0886.2 6 bp overlap
EN1 1 dataset
Motif DE_36h DE_36h-EN1_MA0027.3 6 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 448 bp overlap
ERF::FOXI1 1 dataset
Motif DE_36h DE_36h-ERFFOXI1_MA1935.2 10 bp overlap
ERF::NHLH1 1 dataset
Motif DE_36h DE_36h-ERFNHLH1_MA1938.2 16 bp overlap
ESX1 1 dataset
Motif DE_36h DE_36h-ESX1_MA0644.3 7 bp overlap
ETV2 1 dataset
Motif DE_36h DE_36h-ETV2_MA0762.2 9 bp overlap
ETV2::FOXI1 1 dataset
Motif DE_36h DE_36h-ETV2FOXI1_MA1942.2 11 bp overlap
EVX1 1 dataset
Motif DE_36h DE_36h-EVX1_MA0887.2 6 bp overlap
EVX2 1 dataset
Motif DE_36h DE_36h-EVX2_MA0888.2 6 bp overlap
EZH2 1 dataset
ChIP A-1847_CARM1-KO GSE95643.EZH2.A-1847_CARM1-KO 116 bp overlap
Ebf2 2 datasets
Motif DE_36h DE_36h-Ebf2_MA1604.2 9 bp overlap
Motif DE_48h DE_48h-Ebf2_MA1604.2 9 bp overlap
Erg 1 dataset
Motif DE_36h DE_36h-Erg_MA0474.4 10 bp overlap
FLI1::FOXI1 1 dataset
Motif DE_36h DE_36h-FLI1FOXI1_MA1950.2 11 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 535 bp overlap
ChIP DE DE-FOXA2-2 535 bp overlap
FOXD2 2 datasets
Motif DE_36h DE_36h-FOXD2_MA0847.4 11 bp overlap
Motif DE_48h DE_48h-FOXD2_MA0847.4 11 bp overlap
FOXD3 1 dataset
Motif DE_36h DE_36h-FOXD3_MA0041.3 14 bp overlap
FOXE1 2 datasets
Motif DE_36h DE_36h-FOXE1_MA1487.3 12 bp overlap
Motif DE_48h DE_48h-FOXE1_MA1487.3 12 bp overlap
FOXN3 1 dataset
Motif DE_36h DE_36h-FOXN3_MA1489.1 8 bp overlap
FOXO1::ELF1 1 dataset
Motif DE_36h DE_36h-FOXO1ELF1_MA1953.2 13 bp overlap
FOXO1::ELK1 1 dataset
Motif DE_36h DE_36h-FOXO1ELK1_MA1954.2 13 bp overlap
FOXP2 1 dataset
Motif DE_36h DE_36h-FOXP2_MA0593.2 9 bp overlap
GABPA 1 dataset
Motif DE_36h DE_36h-GABPA_MA0062.4 10 bp overlap
GATA4 3 datasets
ChIP DE DE-GATA4-1 535 bp overlap
ChIP DE DE-GATA4-2 535 bp overlap
ChIP foregut GSE117136.GATA4.foregut 315 bp overlap
GATA6 10 datasets
ChIP DE DE-GATA6-1 535 bp overlap
ChIP DE DE-GATA6-2 535 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 422 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 535 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 535 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 535 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 535 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 535 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 492 bp overlap
ChIP foregut GSE117136.GATA6.foregut 345 bp overlap
GLIS1 2 datasets
ChIP HEK293 ENCFF299RSE 297 bp overlap
ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 410 bp overlap
GSX1 1 dataset
Motif DE_36h DE_36h-GSX1_MA0892.2 6 bp overlap
HNF4A 3 datasets
Motif DE_36h DE_36h-HNF4A_MA1494.2 14 bp overlap
Motif DE_48h DE_48h-HNF4A_MA1494.2 14 bp overlap
Motif DE_60h DE_60h-HNF4A_MA1494.2 14 bp overlap
HOXA1 1 dataset
Motif DE_36h DE_36h-HOXA1_MA1495.2 6 bp overlap
HOXA2 1 dataset
Motif DE_36h DE_36h-HOXA2_MA0900.3 6 bp overlap
HOXB2 1 dataset
Motif DE_36h DE_36h-HOXB2_MA0902.3 6 bp overlap
HOXB3 1 dataset
Motif DE_36h DE_36h-HOXB3_MA0903.2 6 bp overlap
HOXB5 1 dataset
Motif DE_36h DE_36h-HOXB5_MA0904.3 6 bp overlap
HOXC8 1 dataset
Motif DE_36h DE_36h-HOXC8_MA1505.2 6 bp overlap
IKZF1 1 dataset
Motif DE_36h DE_36h-IKZF1_MA1508.2 8 bp overlap
IRF7 1 dataset
Motif DE_36h DE_36h-IRF7_MA0772.2 13 bp overlap
ISX 1 dataset
Motif DE_36h DE_36h-ISX_MA0654.2 6 bp overlap
KLF1 1 dataset
ChIP HEK293 ENCSR859BMR.KLF1.HEK293 275 bp overlap
KLF11 1 dataset
Motif DE_36h DE_36h-KLF11_MA1512.2 10 bp overlap
KLF16 1 dataset
Motif DE_36h DE_36h-KLF16_MA0741.1 11 bp overlap
KLF9 1 dataset
Motif DE_36h DE_36h-KLF9_MA1107.3 11 bp overlap
LHX6 1 dataset
Motif DE_36h DE_36h-LHX6_MA0658.2 8 bp overlap
LMX1A 1 dataset
Motif DE_36h DE_36h-LMX1A_MA0702.3 7 bp overlap
LMX1B 1 dataset
Motif DE_36h DE_36h-LMX1B_MA0703.3 8 bp overlap
Lhx4 1 dataset
Motif DE_36h DE_36h-Lhx4_MA0704.2 6 bp overlap
Lhx8 1 dataset
Motif DE_36h DE_36h-Lhx8_MA0705.2 6 bp overlap
MIXL1 1 dataset
Motif DE_36h DE_36h-MIXL1_MA0662.2 6 bp overlap
MNX1 1 dataset
Motif DE_36h DE_36h-MNX1_MA0707.3 6 bp overlap
MYB 2 datasets
Motif DE_36h DE_36h-MYB_MA0100.4 6 bp overlap
Motif DE_48h DE_48h-MYB_MA0100.4 6 bp overlap
NANOG 1 dataset
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 281 bp overlap
NKX6-1 1 dataset
Motif DE_36h DE_36h-NKX6-1_MA0674.2 7 bp overlap
NKX6-2 1 dataset
Motif DE_36h DE_36h-NKX6-2_MA0675.2 6 bp overlap
NOTO 1 dataset
Motif DE_36h DE_36h-NOTO_MA0710.2 7 bp overlap
Nr2e3 1 dataset
Motif DE_36h DE_36h-Nr2e3_MA0164.2 6 bp overlap
PAX4 1 dataset
Motif DE_36h DE_36h-PAX4_MA0068.2 8 bp overlap
PBX1 1 dataset
Motif DE_36h DE_36h-PBX1_MA0070.2 9 bp overlap
PDX1 1 dataset
Motif DE_36h DE_36h-PDX1_MA0132.3 6 bp overlap
PLAG1 1 dataset
Motif DE_36h DE_36h-PLAG1_MA0163.1 14 bp overlap
POU2F1::SOX2 1 dataset
Motif DE_36h DE_36h-POU2F1SOX2_MA1962.1 17 bp overlap
POU6F1 1 dataset
Motif DE_36h DE_36h-POU6F1_MA0628.2 6 bp overlap
PRDM12 1 dataset
ChIP HEK293 ENCSR760AAY.PRDM12.HEK293 119 bp overlap
PROX1 1 dataset
Motif DE_36h DE_36h-PROX1_MA0794.1 12 bp overlap
PRRX1 1 dataset
Motif DE_36h DE_36h-PRRX1_MA0716.2 6 bp overlap
Pou5f1::Sox2 1 dataset
Motif DE_36h DE_36h-Pou5f1Sox2_MA0142.1 15 bp overlap
RARA 1 dataset
Motif DE_36h DE_36h-RARA_MA0730.1 17 bp overlap
RAX2 1 dataset
Motif DE_36h DE_36h-RAX2_MA0717.2 6 bp overlap
REST 4 datasets
ChIP A549 ENCFF148AIS 107 bp overlap
ChIP HEK293 ENCSR896UBV.REST.HEK293 93 bp overlap
ChIP colorectal-cancer_shCDH1 GSE112555.REST.colorectal-cancer_shCDH1 505 bp overlap
ChIP colorectal-cancer_shCTRL_intact GSE112555.REST.colorectal-cancer_shCTRL_intact 291 bp overlap
RORA 1 dataset
Motif DE_36h DE_36h-RORA_MA0071.1 10 bp overlap
Rarb 1 dataset
Motif DE_36h DE_36h-Rarb_MA0858.1 17 bp overlap
Rhox11 1 dataset
Motif DE_36h DE_36h-Rhox11_MA0629.2 9 bp overlap
Runx1 1 dataset
Motif DE_36h DE_36h-Runx1_MA0002.3 9 bp overlap
SHOX 1 dataset
Motif DE_36h DE_36h-SHOX_MA0630.2 6 bp overlap
SMAD2 2 datasets
Motif DE_36h DE_36h-SMAD2_MA1964.2 6 bp overlap
ChIP endoderm GSE29422.SMAD2.endoderm 133 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 478 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 259 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 303 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 305 bp overlap
SMARCA4 1 dataset
ChIP hiPSC GSE124903.SMARCA4.hiPSC 159 bp overlap
SMARCC1 1 dataset
ChIP DE_D1 S15-DE-d1-BAF155-exp1 264 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 485 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 517 bp overlap
SOX2 1 dataset
ChIP hiPSC GSE56567.SOX2.hiPSC 213 bp overlap
SP3 1 dataset
Motif DE_36h DE_36h-SP3_MA0746.3 11 bp overlap
SRY 1 dataset
Motif DE_36h DE_36h-SRY_MA0084.2 7 bp overlap
STAT1::STAT2 1 dataset
Motif DE_36h DE_36h-STAT1STAT2_MA0517.2 13 bp overlap
Shox2 1 dataset
Motif DE_36h DE_36h-Shox2_MA0720.2 6 bp overlap
Sox6 1 dataset
Motif DE_36h DE_36h-Sox6_MA0515.1 10 bp overlap
Spz1 1 dataset
Motif DE_36h DE_36h-Spz1_MA0111.1 11 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 357 bp overlap
TBX5 1 dataset
Motif DE_36h DE_36h-TBX5_MA0807.1 8 bp overlap
TEAD2 2 datasets
Motif DE_36h DE_36h-TEAD2_MA1121.2 7 bp overlap
Motif DE_48h DE_48h-TEAD2_MA1121.2 7 bp overlap
TEAD4 2 datasets
Motif DE_36h DE_36h-TEAD4_MA0809.3 8 bp overlap
Motif DE_48h DE_48h-TEAD4_MA0809.3 8 bp overlap
THRA 1 dataset
Motif DE_36h DE_36h-THRA_MA1969.2 18 bp overlap
TLX2 1 dataset
Motif DE_36h DE_36h-TLX2_MA1577.2 6 bp overlap
UNCX 1 dataset
Motif DE_36h DE_36h-UNCX_MA0721.2 6 bp overlap
VAX1 1 dataset
Motif DE_36h DE_36h-VAX1_MA0722.2 7 bp overlap
VAX2 1 dataset
Motif DE_36h DE_36h-VAX2_MA0723.3 6 bp overlap
VSX1 1 dataset
Motif DE_36h DE_36h-VSX1_MA0725.2 7 bp overlap
VSX2 1 dataset
Motif DE_36h DE_36h-VSX2_MA0726.2 7 bp overlap
YY1 1 dataset
ChIP Hep-G2_RBM25-KD GSE120104.YY1.Hep-G2_RBM25-KD 253 bp overlap
ZBTB11 2 datasets
ChIP HEK293 ENCFF262GZJ 65 bp overlap
ChIP HEK293 ENCSR882ZTS.ZBTB11.HEK293 95 bp overlap
ZBTB21 2 datasets
ChIP HEK293 ENCFF509WYZ 242 bp overlap
ChIP HEK293 ENCSR321MSF.ZBTB21.HEK293 155 bp overlap
ZBTB8A 2 datasets
ChIP HEK293 ENCFF303WRD 69 bp overlap
ChIP HEK293 ENCSR481FEC.ZBTB8A.HEK293 145 bp overlap
ZC3H11A 1 dataset
ChIP A-549 ENCSR277OOQ.ZC3H11A.A-549 111 bp overlap
ZFP14 1 dataset
Motif DE_36h DE_36h-ZFP14_MA1972.1 15 bp overlap
ZIM3 1 dataset
Motif DE_36h DE_36h-ZIM3_MA1709.2 11 bp overlap
ZNF101 1 dataset
ChIP HEK293 ENCSR462FWS.ZNF101.HEK293 180 bp overlap
ZNF140 1 dataset
ChIP HEK293 ENCSR464KFG.ZNF140.HEK293 83 bp overlap
ZNF213 1 dataset
ChIP HEK293 ENCSR295GRB.ZNF213.HEK293 92 bp overlap
ZNF223 1 dataset
ChIP HEK293 ENCSR906PCS.ZNF223.HEK293 80 bp overlap
ZNF24 1 dataset
ChIP HEK293 ENCSR984MDV.ZNF24.HEK293 100 bp overlap
ZNF266 1 dataset
ChIP HEK293 ENCSR466VYP.ZNF266.HEK293 114 bp overlap
ZNF317 2 datasets
Motif DE_36h DE_36h-ZNF317_MA1593.2 8 bp overlap
Motif DE_48h DE_48h-ZNF317_MA1593.2 8 bp overlap
ZNF34 2 datasets
ChIP HEK293 ENCFF481TFV 118 bp overlap
ChIP HEK293 ENCSR727PIC.ZNF34.HEK293 174 bp overlap
ZNF341 2 datasets
ChIP HEK293 ENCFF944VMC 145 bp overlap
ChIP HEK293 ENCSR185FOY.ZNF341.HEK293 80 bp overlap
ZNF394 2 datasets
ChIP HEK293 ENCFF236OPX 83 bp overlap
ChIP HEK293 ENCSR125DNC.ZNF394.HEK293 154 bp overlap
ZNF398 1 dataset
ChIP HEK293 ENCSR676ZEF.ZNF398.HEK293 333 bp overlap
ZNF404 1 dataset
ChIP HEK293 ENCFF538SAN 90 bp overlap
ZNF418 2 datasets
Motif DE_36h DE_36h-ZNF418_MA1980.1 15 bp overlap
Motif DE_48h DE_48h-ZNF418_MA1980.1 15 bp overlap
ZNF426 2 datasets
ChIP HEK293 ENCFF957XYN 90 bp overlap
ChIP HEK293 ENCSR224NFP.ZNF426.HEK293 157 bp overlap
ZNF433 2 datasets
ChIP HEK293 ENCFF115FJL 78 bp overlap
ChIP HEK293 ENCSR586BRJ.ZNF433.HEK293 56 bp overlap
ZNF510 1 dataset
ChIP HEK293 ENCFF202BSY 81 bp overlap
ZNF518A 2 datasets
ChIP HEK293 ENCFF892ULS 61 bp overlap
ChIP HEK293 ENCSR159GFL.ZNF518A.HEK293 148 bp overlap
ZNF530 1 dataset
ChIP HEK293 ENCFF931DWM 89 bp overlap
ZNF555 1 dataset
ChIP HEK293 ENCSR767XSF.ZNF555.HEK293 77 bp overlap
ZNF560 1 dataset
ChIP HEK293 ENCFF901CEW 61 bp overlap
ZNF577 1 dataset
ChIP HEK293 ENCSR776MDR.ZNF577.HEK293 96 bp overlap
ZNF580 1 dataset
ChIP HEK293 ENCSR668HOP.ZNF580.HEK293 107 bp overlap
ZNF623 1 dataset
ChIP HEK293 ENCSR022IZK.ZNF623.HEK293 129 bp overlap
ZNF629 1 dataset
ChIP HEK293 ENCSR351NON.ZNF629.HEK293 97 bp overlap
ZNF654 1 dataset
ChIP HEK293 ENCFF636WIC 94 bp overlap
ZNF664 2 datasets
ChIP HEK293 ENCFF343XSW 101 bp overlap
ChIP HEK293 ENCSR714LZQ.ZNF664.HEK293 101 bp overlap
ZNF680 1 dataset
ChIP HEK293 ENCFF418WHE 98 bp overlap
ZNF697 1 dataset
ChIP HEK293 ENCSR217QCK.ZNF697.HEK293 143 bp overlap
ZNF770 2 datasets
ChIP HEK293 ENCSR242BGR.ZNF770.HEK293 371 bp overlap
ChIP HEK293 GSE76494.ZNF770.HEK293 326 bp overlap
ZNF781 1 dataset
ChIP HEK293 ENCSR777YSB.ZNF781.HEK293 84 bp overlap
ZSCAN16 3 datasets
Motif DE_36h DE_36h-ZSCAN16_MA2100.1 18 bp overlap
Motif DE_48h DE_48h-ZSCAN16_MA2100.1 18 bp overlap
Motif DE_60h DE_60h-ZSCAN16_MA2100.1 18 bp overlap
ZXDB 1 dataset
ChIP HEK293 ENCSR559IOZ.ZXDB.HEK293 84 bp overlap
mix-a 1 dataset
Motif DE_36h DE_36h-mix-a_MA0621.2 7 bp overlap
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