chr12:113,514,969–113,515,472

chr12 : 113,514,969 – 113,515,472

503 bp 83 TFs 6 linked genes

This 503 bp open chromatin element is linked to 6 target genes and is bound by 83 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
LHX5-AS1		36.7 kb	Distal	Multiome
LHX5		43.4 kb	Distal	Multiome
PLBD2		156.7 kb	Distal	Multiome
SLC8B1		180.2 kb	Distal	Multiome
LINC01234		258.4 kb	Distal	Multiome
TPCN1		293.9 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

83 transcription factors

ASH2L 2 datasets

ChIP H1 ENCFF399KAM 171 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 503 bp overlap

ChIP WA01 ENCSR000BQU.ATF2.WA01 152 bp overlap

BCL11A 1 dataset

ChIP WA01 ENCSR000BMJ.BCL11A.WA01 125 bp overlap

BCOR 4 datasets

ChIP WA01 GSE104690.BCOR.WA01 500 bp overlap

ChIP WA01_KDM2B_KO GSE104690.BCOR.WA01_KDM2B_KO 503 bp overlap

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 503 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 503 bp overlap

ChIP HUES-64 GSE104059.BRD1.HUES-64 404 bp overlap

BRD4 5 datasets

ChIP COLO-741 GSE73319.BRD4.COLO-741 282 bp overlap

ChIP cortical-interneuron GSE117508.BRD4.cortical-interneuron 184 bp overlap

ChIP cortical-interneuron_KCl-pos GSE117508.BRD4.cortical-interneuron_KCl-pos 286 bp overlap

ChIP hESC GSE33281.BRD4.hESC 62 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 153 bp overlap

ChIP WTC11 ENCFF113HIY 399 bp overlap

ChIP K-562 ENCSR000ATU.CBX2.K-562 473 bp overlap

CREB1 1 dataset

ChIP WA01 ENCSR000BSN.CREB1.WA01 107 bp overlap

CTBP2 2 datasets

ChIP H1 ENCFF329MAX 376 bp overlap

ChIP WA01 ENCSR000EUO.CTBP2.WA01 258 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF364PUR 55 bp overlap

ChIP WTC11 ENCFF449LLF 467 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 109 bp overlap

Motif ES_0h ES_0h-EBF3_MA1637.2 9 bp overlap

EGR1 2 datasets

ChIP H1 ENCFF451BLH 261 bp overlap

ChIP WA01 ENCSR000BJA.EGR1.WA01 144 bp overlap

EP300 3 datasets

ChIP H1 ENCFF927IYK 297 bp overlap

ChIP WA01 ENCSR000BKK.EP300.WA01 140 bp overlap

ChIP osteoblast ENCSR000AUD.EP300.osteoblast 377 bp overlap

ChIP SKNO-1 GSE23730.ERG.SKNO-1 195 bp overlap

ChIP MCF-7_aldosterone GSE99626.ESR1.MCF-7_aldosterone 308 bp overlap

ChIP WTC11 ENCFF812SCD 256 bp overlap

EZH2 24 datasets

ChIP A-1847 GSE95643.EZH2.A-1847 503 bp overlap

ChIP A-673 ENCSR179SAO.EZH2.A-673 503 bp overlap

ChIP A673 ENCFF790MVL 483 bp overlap

ChIP A673 ENCFF955JRZ 483 bp overlap

ChIP A673 ENCFF955JRZ 258 bp overlap

ChIP DND41 ENCSR000ASW.EZH2.DND41 503 bp overlap

ChIP GM23338 ENCSR045YHA.EZH2.GM23338 503 bp overlap

ChIP H1 ENCFF232NZA 503 bp overlap

ChIP Hep-3B2-1-7 GSE128137.EZH2.Hep-3B2-1-7 503 bp overlap

ChIP LNCaP-abl GSE39459.EZH2.LNCaP-abl 435 bp overlap

ChIP T98G GSE112240.EZH2.T98G 503 bp overlap

ChIP THP-1 GSE135024.EZH2.THP-1 499 bp overlap

ChIP VCaP_DHAT_2H GSE28950.EZH2.VCaP_DHAT_2H 344 bp overlap

ChIP VCaP_ETOH GSE28950.EZH2.VCaP_ETOH 344 bp overlap

ChIP WA01 ENCSR000ASY.EZH2.WA01 465 bp overlap

ChIP astrocyte ENCSR000ARR.EZH2.astrocyte 229 bp overlap

ChIP dermal-fibroblast_Transformed GSE126396.EZH2.dermal-fibroblast_Transformed 72 bp overlap

ChIP dermal-fibroblast_Untransformed GSE126396.EZH2.dermal-fibroblast_Untransformed 336 bp overlap

ChIP epithelial_mammary ENCSR000ARE.EZH2.epithelial_mammary 238 bp overlap

ChIP hepatocyte ENCFF552DZB 503 bp overlap

ChIP hepatocyte ENCSR384LYW.EZH2.hepatocyte 503 bp overlap

ChIP keratinocyte ENCFF070STK 154 bp overlap

ChIP neural progenitor cell ENCFF018MKA 503 bp overlap

ChIP neural progenitor cell ENCFF018MKA 278 bp overlap

EZH2_phosphoT487 2 datasets

ChIP PC-9 ENCSR702GMW.EZH2_phosphoT487.PC-9 238 bp overlap

ChIP hepatocyte ENCSR341VYI.EZH2_phosphoT487.hepatocyte 471 bp overlap

Motif ES_0h ES_0h-Ebf2_MA1604.2 9 bp overlap

FOXP1 1 dataset

ChIP H9 GSE31006.FOXP1.H9 342 bp overlap

GATA6 3 datasets

ChIP DE_D1 S41-DE-d1-GATA6-exp2 205 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 397 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 265 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 503 bp overlap

GRHL2 1 dataset

ChIP T-47D GSE99680.GRHL2.T-47D 164 bp overlap

GTF3C2 1 dataset

ChIP H9 GSE94418.GTF3C2.H9 189 bp overlap

HDAC2 3 datasets

ChIP H1 ENCFF939VKA 237 bp overlap

ChIP WA01 ENCSR000AVB.HDAC2.WA01 242 bp overlap

ChIP WA01 ENCSR000BNR.HDAC2.WA01 135 bp overlap

HNRNPLL 2 datasets

ChIP K-562 GSE120104.HNRNPLL.K-562 187 bp overlap

ChIP K-562 ENCSR112RNT.HNRNPLL.K-562 217 bp overlap

INO80 1 dataset

ChIP Huh-7 GSE97411.INO80.Huh-7 228 bp overlap

JARID2 2 datasets

ChIP MRC-5_IPS25_CTR GSE48515.JARID2.MRC-5_IPS25_CTR 420 bp overlap

ChIP MRC-5_IPS25_MEG3 GSE48515.JARID2.MRC-5_IPS25_MEG3 503 bp overlap

ChIP ESC S24-ESC-d0-JUN-exp1 355 bp overlap

ChIP ESC S34-ESC-d0-JUN-exp2 277 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 503 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 503 bp overlap

KDM1A 3 datasets

ChIP H1 ENCFF696SGD 296 bp overlap

ChIP H1 ENCFF696SGD 82 bp overlap

ChIP pancreatic-progenitor_GT GSE104840.KDM1A.pancreatic-progenitor_GT 60 bp overlap

KDM4A 2 datasets

ChIP H1 ENCFF078LED 326 bp overlap

ChIP WA01 ENCSR000AVC.KDM4A.WA01 155 bp overlap

ChIP hESC_PRIMED GSE69646.MED1.hESC_PRIMED 356 bp overlap

ChIP DU145_SH4 GSE135623.MTF2.DU145_SH4 368 bp overlap

NANOG 4 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 423 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 334 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 452 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 314 bp overlap

NCOA2 1 dataset

ChIP MCF-7_E2 ERP000901.NCOA2.MCF-7_E2 118 bp overlap

NFKB1 1 dataset

ChIP HEK293T GSE129618.NFKB1.HEK293T 205 bp overlap

NIPBL 1 dataset

ChIP WA09_heat-shock GSE105028.NIPBL.WA09_heat-shock 380 bp overlap

NRIP1 1 dataset

ChIP MCF-7_E2 ERP005838.NRIP1.MCF-7_E2 127 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 503 bp overlap

ChIP hiPSC_derived_PPs GSE106949.PDX1.hiPSC_derived_PPs 234 bp overlap

PHF8 2 datasets

ChIP H1 ENCFF427UFV 375 bp overlap

ChIP H1 ENCFF427UFV 407 bp overlap

POU5F1 6 datasets

ChIP BG03 GSE21614.POU5F1.BG03 153 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 474 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 503 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 503 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 340 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 397 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 412 bp overlap

PRDM14 2 datasets

ChIP NCCIT GSE71675.PRDM14.NCCIT 503 bp overlap

ChIP primordial-germ-cell-like-cell GSE138674.PRDM14.primordial-germ-cell-like-cell 331 bp overlap

RAD21 2 datasets

ChIP WA09 GSE105028.RAD21.WA09 286 bp overlap

ChIP WA09_heat-shock GSE105028.RAD21.WA09_heat-shock 360 bp overlap

RARA 2 datasets

ChIP hiPSC_D2 GSE132532.RARA.hiPSC_D2 282 bp overlap

ChIP hiPSC_D4 GSE109172.RARA.hiPSC_D4 200 bp overlap

RBBP5 2 datasets

ChIP H1 ENCFF905HFL 222 bp overlap

ChIP WA01 ENCSR000AQC.RBBP5.WA01 503 bp overlap

RNF2 3 datasets

ChIP WA01 GSE104690.RNF2.WA01 330 bp overlap

ChIP WA09 GSE105028.RNF2.WA09 503 bp overlap

ChIP WA09_heat-shock GSE105028.RNF2.WA09_heat-shock 503 bp overlap

ChIP WA01 GSE104690.RYBP.WA01 503 bp overlap

SALL3 1 dataset

ChIP hiPSC GSE104863.SALL3.hiPSC 410 bp overlap

SAP30 1 dataset

ChIP WA01 ENCSR000ATR.SAP30.WA01 170 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 338 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 443 bp overlap

SMAD2_3 2 datasets

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 297 bp overlap

ChIP ESC S33-ESC-d0-SMAD2_3-exp2 267 bp overlap

SMAD3 1 dataset

ChIP BG03_DIFF_2H GSE36578.SMAD3.BG03_DIFF_2H 255 bp overlap

SMARCA4 2 datasets

ChIP hiPSC GSE124903.SMARCA4.hiPSC 408 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 211 bp overlap

SMARCB1 1 dataset

ChIP hiPSC GSE124903.SMARCB1.hiPSC 271 bp overlap

SMARCC1 1 dataset

ChIP hiPSC GSE124903.SMARCC1.hiPSC 324 bp overlap

SOX21 1 dataset

ChIP neuroepithelilal-cells GSE110505.SOX21.neuroepithelilal-cells 503 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 245 bp overlap

ChIP WA01 ENCSR000BQV.SP4.WA01 58 bp overlap

ChIP K-562 GSE70482.SPI1.K-562 151 bp overlap

SRSF3 1 dataset

ChIP K-562 GSE120104.SRSF3.K-562 214 bp overlap

STAT1 1 dataset

ChIP CD14 GSE43036.STAT1.CD14 255 bp overlap

SUZ12 8 datasets

ChIP Aska-SS GSE108025.SUZ12.Aska-SS 376 bp overlap

ChIP CRL-7250_shSS18-SSX GSE108025.SUZ12.CRL-7250_shSS18-SSX 503 bp overlap

ChIP H1 ENCFF881NFR 503 bp overlap

ChIP Karpas-422_CPI360-D4 GSE134136.SUZ12.Karpas-422_CPI360-D4 258 bp overlap

ChIP Karpas-422_CPI360-D8 GSE134136.SUZ12.Karpas-422_CPI360-D8 330 bp overlap

ChIP LNCaP GSE39459.SUZ12.LNCaP 197 bp overlap

ChIP hiPSC GSE124903.SUZ12.hiPSC 503 bp overlap

ChIP hiPSC_WT GSE124903.SUZ12.hiPSC_WT 243 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 235 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 291 bp overlap

ChIP PRIMA5 GSE33850.TAL1.PRIMA5 220 bp overlap

TEAD4 1 dataset

ChIP H1 ENCFF778PAX 103 bp overlap

TFAP2A 1 dataset

ChIP WA09 GSE105081.TFAP2A.WA09 143 bp overlap

TFAP2C 2 datasets

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 503 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 415 bp overlap

TP53 2 datasets

ChIP WTC11 ENCFF359JCU 239 bp overlap

ChIP hESC_DIFF GSE39912.TP53.hESC_DIFF 297 bp overlap

ChIP H1 ENCFF524BTL 337 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 358 bp overlap

ZNF148 1 dataset

ChIP K-562 GSE121133.ZNF148.K-562 252 bp overlap

ZNF180 1 dataset

ChIP HEK293T GSE78099.ZNF180.HEK293T 103 bp overlap

ZNF207 1 dataset

ChIP WA09 GSE118632.ZNF207.WA09 380 bp overlap

ZNF281 2 datasets

Motif ES_0h ES_0h-ZNF281_MA1630.3 10 bp overlap

ChIP K-562 GSE121133.ZNF281.K-562 156 bp overlap

ZNF398 1 dataset

ChIP H9 GSE133630.ZNF398.H9 249 bp overlap

ZNF423 1 dataset

ChIP WTC11 ENCFF574PBR 112 bp overlap

ZNF454 1 dataset

Motif ES_0h ES_0h-ZNF454_MA1712.2 17 bp overlap

ZNF467 1 dataset

ChIP HEK293 GSE76494.ZNF467.HEK293 181 bp overlap

ZNF519 1 dataset

ChIP HEK293T GSE78099.ZNF519.HEK293T 161 bp overlap