chr10 : 75,415,208 – 75,415,840

632 bp 151 TFs 2 linked genes

This 632 bp open chromatin element is linked to ENSG00000273248 and ENSG00000272692 and is bound by 151 transcription factors.

Linked Genes

2 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000273248		5.6 kb	Proximal	Proximity
ENSG00000272692		6.1 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

151 transcription factors

ALX3 1 dataset

Motif DE_24h DE_24h-ALX3_MA0634.2 6 bp overlap

AR 1 dataset

ChIP breast_tumor_Male_26 GSE104399.AR.breast_tumor_Male_26 235 bp overlap

ARGFX 1 dataset

Motif DE_24h DE_24h-ARGFX_MA1463.2 8 bp overlap

ASCL1 1 dataset

ChIP NCI-H889 GSE69394.ASCL1.NCI-H889 109 bp overlap

BCOR 2 datasets

ChIP WA01_KDM2B_KO GSE104690.BCOR.WA01_KDM2B_KO 270 bp overlap

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 330 bp overlap

BRD4 1 dataset

ChIP HEK293T GSE39579.BRD4.HEK293T 164 bp overlap

CTNNB1 2 datasets

ChIP hiPSC_D2 GSE132532.CTNNB1.hiPSC_D2 250 bp overlap

ChIP hiPSC_TT-neg_D2 GSE132532.CTNNB1.hiPSC_TT-neg_D2 172 bp overlap

DRGX 1 dataset

Motif DE_24h DE_24h-DRGX_MA1481.2 6 bp overlap

EHF 1 dataset

Motif DE_12h DE_12h-EHF_MA0598.4 9 bp overlap

ELF1 1 dataset

Motif DE_12h DE_12h-ELF1_MA0473.4 9 bp overlap

ELF3 1 dataset

Motif DE_12h DE_12h-ELF3_MA0640.3 9 bp overlap

ELK1::HOXA1 1 dataset

Motif DE_12h DE_12h-ELK1HOXA1_MA1931.1 14 bp overlap

ELK4 1 dataset

Motif DE_12h DE_12h-ELK4_MA0076.3 9 bp overlap

EMX1 1 dataset

Motif DE_24h DE_24h-EMX1_MA0612.3 6 bp overlap

EMX2 1 dataset

Motif DE_24h DE_24h-EMX2_MA0886.2 6 bp overlap

EN1 1 dataset

Motif DE_24h DE_24h-EN1_MA0027.3 6 bp overlap

EN2 1 dataset

Motif DE_24h DE_24h-EN2_MA0642.3 7 bp overlap

EOMES 1 dataset

Motif DE_12h DE_12h-EOMES_MA0800.2 9 bp overlap

ERG 1 dataset

ChIP MCF-7 GSE23730.ERG.MCF-7 204 bp overlap

ESR1 5 datasets

ChIP U2OS_100nM-E2 GSE151039.ESR1.U2OS_100nM-E2 157 bp overlap

ChIP U2OS_10nM-E2 GSE151039.ESR1.U2OS_10nM-E2 125 bp overlap

ChIP U2OS_10nM-E2-B GSE151039.ESR1.U2OS_10nM-E2-B 123 bp overlap

ChIP U2OS_E2 GSE26110.ESR1.U2OS_E2 118 bp overlap

ChIP primary-endometrium-cancer_E1_DSG GSE114737.ESR1.primary-endometrium-cancer_E1_DSG 130 bp overlap

ESX1 1 dataset

Motif DE_24h DE_24h-ESX1_MA0644.3 7 bp overlap

ETS1 1 dataset

ChIP cardiomyocyte_D2 GSE129986.ETS1.cardiomyocyte_D2 271 bp overlap

ETV1 1 dataset

Motif DE_12h DE_12h-ETV1_MA0761.3 9 bp overlap

ETV6 1 dataset

Motif DE_12h DE_12h-ETV6_MA0645.2 9 bp overlap

ETV7 1 dataset

Motif DE_12h DE_12h-ETV7_MA1708.2 9 bp overlap

EVX1 1 dataset

Motif DE_24h DE_24h-EVX1_MA0887.2 6 bp overlap

EVX2 1 dataset

Motif DE_24h DE_24h-EVX2_MA0888.2 6 bp overlap

EZH2 4 datasets

ChIP GM23338 ENCSR045YHA.EZH2.GM23338 238 bp overlap

ChIP H1 ENCFF232NZA 632 bp overlap

ChIP H1 ENCFF232NZA 546 bp overlap

ChIP WA01 ENCSR000ASY.EZH2.WA01 426 bp overlap

EZH2_phosphoT487 1 dataset

ChIP neuron_bipolar_doxy_4d ENCSR886KKK.EZH2_phosphoT487.neuron_bipolar_doxy_4d 253 bp overlap

Elf5 1 dataset

Motif DE_12h DE_12h-Elf5_MA0136.4 8 bp overlap

Erg 1 dataset

Motif DE_12h DE_12h-Erg_MA0474.4 10 bp overlap

FIGLA 1 dataset

Motif DE_12h DE_12h-FIGLA_MA0820.2 6 bp overlap

FLI1::DRGX 1 dataset

Motif DE_12h DE_12h-FLI1DRGX_MA1949.2 14 bp overlap

FOXA1 3 datasets

ChIP 22Rv1_CST_Crispr-70 GSE123618.FOXA1.22Rv1_CST_Crispr-70 189 bp overlap

Motif DE_12h DE_12h-FOXA1_MA0148.5 8 bp overlap

ChIP LS180 GSE140533.FOXA1.LS180 62 bp overlap

FOXA2 4 datasets

ChIP DE DE-FOXA2-1 387 bp overlap

ChIP DE DE-FOXA2-2 418 bp overlap

Motif DE_12h DE_12h-FOXA2_MA0047.4 8 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.FOXA2.pancreatic-progenitor_PP1 281 bp overlap

FOXA3 1 dataset

Motif DE_12h DE_12h-FOXA3_MA1683.2 7 bp overlap

FOXB1 1 dataset

Motif DE_12h DE_12h-FOXB1_MA0845.1 11 bp overlap

FOXC1 1 dataset

Motif DE_12h DE_12h-FOXC1_MA0032.2 11 bp overlap

FOXC2 1 dataset

Motif DE_12h DE_12h-FOXC2_MA0846.2 11 bp overlap

FOXD1 1 dataset

Motif DE_12h DE_12h-FOXD1_MA0031.2 7 bp overlap

FOXF2 1 dataset

Motif DE_12h DE_12h-FOXF2_MA0030.2 9 bp overlap

FOXG1 1 dataset

Motif DE_12h DE_12h-FOXG1_MA0613.1 8 bp overlap

FOXI1 1 dataset

Motif DE_12h DE_12h-FOXI1_MA0042.2 7 bp overlap

FOXK1 1 dataset

Motif DE_12h DE_12h-FOXK1_MA0852.3 7 bp overlap

FOXK2 1 dataset

Motif DE_12h DE_12h-FOXK2_MA1103.3 7 bp overlap

FOXL1 1 dataset

Motif DE_12h DE_12h-FOXL1_MA0033.2 7 bp overlap

FOXN3 1 dataset

Motif DE_12h DE_12h-FOXN3_MA1489.1 8 bp overlap

FOXO4 1 dataset

Motif DE_12h DE_12h-FOXO4_MA0848.1 7 bp overlap

FOXO6 1 dataset

Motif DE_12h DE_12h-FOXO6_MA0849.1 7 bp overlap

FOXP1 1 dataset

Motif DE_12h DE_12h-FOXP1_MA0481.4 7 bp overlap

FOXP2 1 dataset

Motif DE_12h DE_12h-FOXP2_MA0593.2 9 bp overlap

FOXP3 1 dataset

Motif DE_12h DE_12h-FOXP3_MA0850.1 7 bp overlap

FOXP4 1 dataset

Motif DE_12h DE_12h-FOXP4_MA2117.1 7 bp overlap

FOXS1 1 dataset

Motif DE_12h DE_12h-FOXS1_MA2118.1 8 bp overlap

Foxf1 1 dataset

Motif DE_12h DE_12h-Foxf1_MA1606.2 7 bp overlap

Foxj2 1 dataset

Motif DE_12h DE_12h-Foxj2_MA0614.1 8 bp overlap

Foxl2 1 dataset

Motif DE_12h DE_12h-Foxl2_MA1607.2 10 bp overlap

Foxo1 1 dataset

Motif DE_12h DE_12h-Foxo1_MA0480.3 7 bp overlap

Foxo3 1 dataset

Motif DE_12h DE_12h-Foxo3_MA0157.4 7 bp overlap

GABPA 1 dataset

Motif DE_12h DE_12h-GABPA_MA0062.4 10 bp overlap

GATA6 6 datasets

ChIP DE_D1 S09-DE-d1-GATA6-exp1 614 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 412 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 77 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 449 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 476 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 632 bp overlap

GBX1 1 dataset

Motif DE_24h DE_24h-GBX1_MA0889.2 7 bp overlap

GSX1 1 dataset

Motif DE_24h DE_24h-GSX1_MA0892.2 6 bp overlap

GSX2 1 dataset

Motif DE_24h DE_24h-GSX2_MA0893.3 7 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 243 bp overlap

HOXA1 1 dataset

Motif DE_24h DE_24h-HOXA1_MA1495.2 6 bp overlap

HOXA2 1 dataset

Motif DE_24h DE_24h-HOXA2_MA0900.3 6 bp overlap

HOXA3 1 dataset

Motif DE_24h DE_24h-HOXA3_MA2119.1 7 bp overlap

HOXB1 1 dataset

Motif DE_24h DE_24h-HOXB1_MA2093.1 7 bp overlap

HOXB2 1 dataset

Motif DE_24h DE_24h-HOXB2_MA0902.3 6 bp overlap

HOXB2::ELK1 1 dataset

Motif DE_12h DE_12h-HOXB2ELK1_MA1957.1 14 bp overlap

HOXB3 1 dataset

Motif DE_24h DE_24h-HOXB3_MA0903.2 6 bp overlap

HOXB5 1 dataset

Motif DE_24h DE_24h-HOXB5_MA0904.3 6 bp overlap

HOXC8 1 dataset

Motif DE_24h DE_24h-HOXC8_MA1505.2 6 bp overlap

HOXD3 1 dataset

Motif DE_24h DE_24h-HOXD3_MA0912.2 8 bp overlap

IKZF2 1 dataset

Motif DE_12h DE_12h-IKZF2_MA2326.1 6 bp overlap

ISX 1 dataset

Motif DE_24h DE_24h-ISX_MA0654.2 6 bp overlap

Ikzf3 1 dataset

Motif DE_12h DE_12h-Ikzf3_MA1992.2 9 bp overlap

JARID2 1 dataset

ChIP MRC-5_IPS25_CTR GSE48515.JARID2.MRC-5_IPS25_CTR 168 bp overlap

JUN 3 datasets

ChIP DE_D1 S08-DE-d1-JUN-exp1 387 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 332 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 447 bp overlap

KLF17 1 dataset

Motif DE_24h DE_24h-KLF17_MA1514.2 14 bp overlap

LBX1 1 dataset

Motif DE_24h DE_24h-LBX1_MA0618.2 7 bp overlap

LHX5 1 dataset

Motif DE_24h DE_24h-LHX5_MA1519.2 7 bp overlap

LHX6 1 dataset

Motif DE_24h DE_24h-LHX6_MA0658.2 8 bp overlap

LHX9 1 dataset

Motif DE_24h DE_24h-LHX9_MA0701.3 7 bp overlap

LMX1A 1 dataset

Motif DE_24h DE_24h-LMX1A_MA0702.3 7 bp overlap

LMX1B 1 dataset

Motif DE_24h DE_24h-LMX1B_MA0703.3 8 bp overlap

Lhx1 1 dataset

Motif DE_24h DE_24h-Lhx1_MA1518.3 10 bp overlap

Lhx4 1 dataset

Motif DE_24h DE_24h-Lhx4_MA0704.2 6 bp overlap

Lhx8 1 dataset

Motif DE_24h DE_24h-Lhx8_MA0705.2 6 bp overlap

MEOX1 1 dataset

Motif DE_24h DE_24h-MEOX1_MA0661.2 7 bp overlap

MEOX2 1 dataset

Motif DE_24h DE_24h-MEOX2_MA0706.2 7 bp overlap

MGA 1 dataset

Motif DE_12h DE_12h-MGA_MA0801.1 8 bp overlap

MGA::EVX1 1 dataset

Motif DE_24h DE_24h-MGAEVX1_MA1960.2 11 bp overlap

MIXL1 1 dataset

Motif DE_24h DE_24h-MIXL1_MA0662.2 6 bp overlap

MNX1 1 dataset

Motif DE_24h DE_24h-MNX1_MA0707.3 6 bp overlap

NANOG 5 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 244 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 327 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 394 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 280 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 301 bp overlap

NIPBL 1 dataset

ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 216 bp overlap

NKX6-2 1 dataset

Motif DE_24h DE_24h-NKX6-2_MA0675.2 6 bp overlap

NOTO 1 dataset

Motif DE_24h DE_24h-NOTO_MA0710.2 7 bp overlap

PDX1 2 datasets

Motif DE_24h DE_24h-PDX1_MA0132.3 6 bp overlap

ChIP hiPSC GSE125768.PDX1.hiPSC 272 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 540 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 560 bp overlap

POU6F1 1 dataset

Motif DE_24h DE_24h-POU6F1_MA0628.2 6 bp overlap

POU6F2 1 dataset

Motif DE_24h DE_24h-POU6F2_MA0793.2 9 bp overlap

PRRX1 1 dataset

Motif DE_24h DE_24h-PRRX1_MA0716.2 6 bp overlap

PRRX2 1 dataset

Motif DE_24h DE_24h-PRRX2_MA0075.4 7 bp overlap

Ptf1A 1 dataset

Motif DE_12h DE_12h-Ptf1A_MA1620.2 8 bp overlap

RAX2 1 dataset

Motif DE_24h DE_24h-RAX2_MA0717.2 6 bp overlap

RNF2 1 dataset

ChIP WA09 GSE105028.RNF2.WA09 569 bp overlap

RREB1 1 dataset

Motif DE_24h DE_24h-RREB1_MA0073.2 19 bp overlap

SHOX 1 dataset

Motif DE_24h DE_24h-SHOX_MA0630.2 6 bp overlap

SMAD2 1 dataset

Motif DE_24h DE_24h-SMAD2_MA1964.2 6 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 468 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 475 bp overlap

SMAD2_3 3 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 437 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 365 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 401 bp overlap

SMARCA4 1 dataset

ChIP hiPSC GSE124903.SMARCA4.hiPSC 380 bp overlap

SMARCB1 1 dataset

ChIP hiPSC GSE124903.SMARCB1.hiPSC 277 bp overlap

SMARCC1 1 dataset

ChIP hiPSC GSE124903.SMARCC1.hiPSC 237 bp overlap

SP5 1 dataset

Motif DE_24h DE_24h-SP5_MA1965.2 6 bp overlap

SUZ12 3 datasets

ChIP H1 ENCFF881NFR 159 bp overlap

ChIP NT2-D1 ENCSR000EXH.SUZ12.NT2-D1 376 bp overlap

ChIP hiPSC_WT GSE124903.SUZ12.hiPSC_WT 183 bp overlap

Shox2 1 dataset

Motif DE_24h DE_24h-Shox2_MA0720.2 6 bp overlap

TBR1 1 dataset

Motif DE_12h DE_12h-TBR1_MA0802.2 9 bp overlap

TBX1 1 dataset

Motif DE_12h DE_12h-TBX1_MA0805.1 8 bp overlap

TBX15 1 dataset

Motif DE_12h DE_12h-TBX15_MA0803.1 8 bp overlap

TBX18 1 dataset

Motif DE_12h DE_12h-TBX18_MA1565.2 9 bp overlap

TBX2 1 dataset

Motif DE_12h DE_12h-TBX2_MA0688.2 9 bp overlap

TBX20 1 dataset

Motif DE_12h DE_12h-TBX20_MA0689.1 11 bp overlap

TBX21 1 dataset

Motif DE_12h DE_12h-TBX21_MA0690.3 10 bp overlap

TBX3 1 dataset

Motif DE_12h DE_12h-TBX3_MA1566.3 9 bp overlap

TBX4 1 dataset

Motif DE_12h DE_12h-TBX4_MA0806.1 8 bp overlap

TBX5 1 dataset

Motif DE_12h DE_12h-TBX5_MA0807.1 8 bp overlap

TLX2 1 dataset

Motif DE_24h DE_24h-TLX2_MA1577.2 6 bp overlap

TP53 1 dataset

ChIP H9 GSE142050.TP53.H9 306 bp overlap

Tbx6 1 dataset

Motif DE_12h DE_12h-Tbx6_MA1567.3 9 bp overlap

UNCX 1 dataset

Motif DE_24h DE_24h-UNCX_MA0721.2 6 bp overlap

VAX1 1 dataset

Motif DE_24h DE_24h-VAX1_MA0722.2 7 bp overlap

VAX2 1 dataset

Motif DE_24h DE_24h-VAX2_MA0723.3 6 bp overlap

VSX1 1 dataset

Motif DE_24h DE_24h-VSX1_MA0725.2 7 bp overlap

VSX2 1 dataset

Motif DE_24h DE_24h-VSX2_MA0726.2 7 bp overlap

ZBTB11 1 dataset

Motif DE_12h DE_12h-ZBTB11_MA2329.1 9 bp overlap

ZBTB18 1 dataset

Motif DE_12h DE_12h-ZBTB18_MA0698.2 11 bp overlap

ZBTB7A 1 dataset

Motif DE_12h DE_12h-ZBTB7A_MA0750.3 9 bp overlap

ZEB1 1 dataset

Motif DE_12h DE_12h-ZEB1_MA0103.4 6 bp overlap

ZNF175 1 dataset

Motif DE_12h DE_12h-ZNF175_MA2332.1 9 bp overlap

ZNF331 1 dataset

Motif DE_12h DE_12h-ZNF331_MA1726.2 10 bp overlap

ZNF460 1 dataset

Motif DE_24h DE_24h-ZNF460_MA1596.1 16 bp overlap

ZNF582 1 dataset

Motif DE_12h DE_12h-ZNF582_MA1983.2 19 bp overlap

ZNF75A 1 dataset

Motif DE_12h DE_12h-ZNF75A_MA2097.1 12 bp overlap

ZSCAN16 1 dataset

Motif DE_24h DE_24h-ZSCAN16_MA2100.1 18 bp overlap

Znf423 1 dataset

Motif DE_12h DE_12h-Znf423_MA0116.1 15 bp overlap

mix-a 1 dataset

Motif DE_24h DE_24h-mix-a_MA0621.2 7 bp overlap