chr1 : 159,909,082 – 159,909,741
659 bp 114 TFs 4 linked genes
This 659 bp open chromatin element is linked to 4 target genes and is bound by 114 transcription factors.
Linked Genes
4 genes
Distance
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ENSG00000279430 812 bp At TSS Proximity
ENSG00000287040 8.6 kb Proximal Proximity
CFAP45 8.9 kb Proximal Proximity
MIR4259 9.0 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr1:159,904,082 – 159,914,741
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
114 transcription factors
Source
Cell type
ARID1A 1 dataset
ChIP 12Z GSE129781.ARID1A.12Z 146 bp overlap
ARID1B 2 datasets
ChIP K-562 ENCSR822CCM.ARID1B.K-562 248 bp overlap
ChIP K562 ENCFF938UXQ 463 bp overlap
BACH1 1 dataset
Motif DE_48h DE_48h-BACH1_MA1633.2 9 bp overlap
BARX1 1 dataset
Motif DE_48h DE_48h-BARX1_MA0875.2 6 bp overlap
BCL11A 1 dataset
ChIP CD34_Day7_30min GSE104676.BCL11A.CD34_Day7_30min 57 bp overlap
BRD2 1 dataset
ChIP K-562_DMSO GSE138084.BRD2.K-562_DMSO 374 bp overlap
BRD4 3 datasets
ChIP HCC1806_100nMtrametinib300nMJQ1_24h GSE87418.BRD4.HCC1806_100nMtrametinib300nMJQ1_24h 234 bp overlap
ChIP K-562_iBET-BD1-IFNG GSE138084.BRD4.K-562_iBET-BD1-IFNG 208 bp overlap
ChIP KOPT-K1_E GSE54379.BRD4.KOPT-K1_E 238 bp overlap
BSX 1 dataset
Motif DE_48h DE_48h-BSX_MA0876.2 6 bp overlap
CBFA2T2 2 datasets
ChIP K-562 ENCSR699PVC.CBFA2T2.K-562 218 bp overlap
ChIP K562 ENCFF963TXY 333 bp overlap
CBFA2T3 2 datasets
ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 389 bp overlap
ChIP K562 ENCFF673OEZ 256 bp overlap
CEBPB 1 dataset
ChIP K-562 ENCSR000EHE.CEBPB.K-562 136 bp overlap
CEBPD 1 dataset
ChIP K-562 ENCSR000BVY.CEBPD.K-562 196 bp overlap
DLX1 1 dataset
Motif DE_48h DE_48h-DLX1_MA0879.3 6 bp overlap
DLX6 1 dataset
Motif DE_48h DE_48h-DLX6_MA0882.2 6 bp overlap
DPF2 1 dataset
ChIP K-562 ENCSR219BXP.DPF2.K-562 214 bp overlap
Dlx2 1 dataset
Motif DE_48h DE_48h-Dlx2_MA0885.3 8 bp overlap
Dlx3 1 dataset
Motif DE_48h DE_48h-Dlx3_MA0880.2 6 bp overlap
Dlx4 1 dataset
Motif DE_48h DE_48h-Dlx4_MA0881.2 6 bp overlap
Dlx5 1 dataset
Motif DE_48h DE_48h-Dlx5_MA1476.3 8 bp overlap
ELF3 1 dataset
ChIP PDAC_KOKLF5 GSE64557.ELF3.PDAC_KOKLF5 243 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 220 bp overlap
EP300 2 datasets
ChIP NB4 GSE126720.EP300.NB4 161 bp overlap
ChIP SK-N-SH ENCFF829RWA 248 bp overlap
ERF::FIGLA 3 datasets
Motif DE_48h DE_48h-ERFFIGLA_MA1934.2 13 bp overlap
Motif DE_60h DE_60h-ERFFIGLA_MA1934.2 13 bp overlap
Motif DE_72h DE_72h-ERFFIGLA_MA1934.2 13 bp overlap
ESR1 4 datasets
ChIP MCF-7_E2+4OHT_SRC-3 GSE119702.ESR1.MCF-7_E2+4OHT_SRC-3 238 bp overlap
ChIP MCF-7_SRC3_OHT GSE119702.ESR1.MCF-7_SRC3_OHT 238 bp overlap
ChIP MCF-7_shFbxo GSE119702.ESR1.MCF-7_shFbxo 142 bp overlap
ChIP MCF-7_shFbxo_E2 GSE119702.ESR1.MCF-7_shFbxo_E2 142 bp overlap
FIGLA 2 datasets
Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap
Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap
FOS::JUN 1 dataset
Motif DE_48h DE_48h-FOSJUN_MA0099.4 9 bp overlap
FOS::JUNB 1 dataset
Motif DE_48h DE_48h-FOSJUNB_MA1134.2 9 bp overlap
FOS::JUND 1 dataset
Motif DE_48h DE_48h-FOSJUND_MA1141.2 9 bp overlap
FOSB::JUNB 1 dataset
Motif DE_48h DE_48h-FOSBJUNB_MA1135.2 9 bp overlap
FOSL1 3 datasets
Motif DE_48h DE_48h-FOSL1_MA0477.3 9 bp overlap
ChIP K-562 ENCSR239ZLZ.FOSL1.K-562 304 bp overlap
ChIP K-562 ENCSR000BMV.FOSL1.K-562 140 bp overlap
FOSL1::JUN 1 dataset
Motif DE_48h DE_48h-FOSL1JUN_MA1128.2 9 bp overlap
FOSL1::JUNB 1 dataset
Motif DE_48h DE_48h-FOSL1JUNB_MA1137.2 9 bp overlap
FOSL1::JUND 1 dataset
Motif DE_48h DE_48h-FOSL1JUND_MA1142.2 8 bp overlap
FOSL2 1 dataset
Motif DE_48h DE_48h-FOSL2_MA0478.2 10 bp overlap
FOSL2::JUN 1 dataset
Motif DE_48h DE_48h-FOSL2JUN_MA1130.2 9 bp overlap
FOSL2::JUNB 1 dataset
Motif DE_48h DE_48h-FOSL2JUNB_MA1138.2 9 bp overlap
FOSL2::JUND 1 dataset
Motif DE_48h DE_48h-FOSL2JUND_MA1144.2 9 bp overlap
FOXA1 4 datasets
ChIP ZR751 GSE72249.FOXA1.ZR751 199 bp overlap
ChIP ZR751_DEX GSE72249.FOXA1.ZR751_DEX 153 bp overlap
ChIP ZR751_E2 GSE72249.FOXA1.ZR751_E2 162 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.FOXA1.pancreatic-progenitor_PP1 215 bp overlap
FOXA2 5 datasets
ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.FOXA2.BJ1-hTERT_FOXA2_GATA4_Coexp 215 bp overlap
ChIP Caco-2 GSE66218.FOXA2.Caco-2 123 bp overlap
ChIP DE DE-FOXA2-1 334 bp overlap
ChIP DE DE-FOXA2-2 393 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.FOXA2.pancreatic-progenitor_PP1 165 bp overlap
FOXL2 2 datasets
ChIP HGrC1_C134W-TGF GSE138496.FOXL2.HGrC1_C134W-TGF 108 bp overlap
ChIP KGN_1513 GSE138496.FOXL2.KGN_1513 74 bp overlap
GATA1 9 datasets
ChIP CD34_Day7_30min GSE104676.GATA1.CD34_Day7_30min 136 bp overlap
ChIP CD34_ERYTH_BIO GSE29194.GATA1.CD34_ERYTH_BIO 200 bp overlap
ChIP CD34_ERYTH_BMP GSE29194.GATA1.CD34_ERYTH_BMP 169 bp overlap
Motif DE_48h DE_48h-GATA1_MA0035.5 7 bp overlap
ChIP HUDEP-2_30min GSE104676.GATA1.HUDEP-2_30min 107 bp overlap
ChIP K-562 GSE107726.GATA1.K-562 270 bp overlap
ChIP K-562 ENCSR000EFT.GATA1.K-562 137 bp overlap
ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 278 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 186 bp overlap
GATA2 9 datasets
ChIP CD34_ACY957 GSE60792.GATA2.CD34_ACY957 160 bp overlap
ChIP K-562 ENCSR000DKA.GATA2.K-562 274 bp overlap
ChIP K-562 ENCSR000BKM.GATA2.K-562 276 bp overlap
ChIP K-562 ENCSR000EWG.GATA2.K-562 141 bp overlap
ChIP K562 ENCFF544PCK 251 bp overlap
ChIP SH-SY5Y ENCFF485YIB 345 bp overlap
ChIP SH-SY5Y ENCSR000EYB.GATA2.SH-SY5Y 261 bp overlap
ChIP SK-N-SH ENCSR706VOO.GATA2.SK-N-SH 156 bp overlap
ChIP WA09 GSE105081.GATA2.WA09 231 bp overlap
GATA3 4 datasets
ChIP CLB-Ga GSE90683.GATA3.CLB-Ga 193 bp overlap
ChIP Jurkat GSE76181.GATA3.Jurkat 206 bp overlap
ChIP Kelly GSE65664.GATA3.Kelly 168 bp overlap
ChIP MCF-7_E2_Dex GSE81510.GATA3.MCF-7_E2_Dex 147 bp overlap
GATA4 6 datasets
ChIP DE DE-GATA4-1 440 bp overlap
ChIP DE DE-GATA4-2 514 bp overlap
ChIP Hep-G2 GSE135714.GATA4.Hep-G2 426 bp overlap
ChIP foregut GSE117136.GATA4.foregut 284 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 412 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 384 bp overlap
GATA6 18 datasets
ChIP AGS GSE51705.GATA6.AGS 286 bp overlap
ChIP AGS GSE51936.GATA6.AGS 174 bp overlap
ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 296 bp overlap
ChIP DE DE-GATA6-1 575 bp overlap
ChIP DE DE-GATA6-2 476 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 340 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 413 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 330 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 449 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 426 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 351 bp overlap
ChIP PATU8988 GSE47535.GATA6.PATU8988 185 bp overlap
ChIP YCC-3 GSE51705.GATA6.YCC-3 263 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 362 bp overlap
ChIP foregut GSE117136.GATA6.foregut 377 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 358 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 300 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 358 bp overlap
GBX2 1 dataset
Motif DE_48h DE_48h-GBX2_MA0890.2 6 bp overlap
GFI1B 1 dataset
ChIP K-562 ENCSR509GDT.GFI1B.K-562 111 bp overlap
GRHL2 4 datasets
Motif DE_48h DE_48h-GRHL2_MA1105.3 8 bp overlap
ChIP MCF-7 GSE109820.GRHL2.MCF-7 203 bp overlap
ChIP MCF-7-WS8_VEH GSE113092.GRHL2.MCF-7-WS8_VEH 340 bp overlap
ChIP OVCA429 GSE71018.GRHL2.OVCA429 250 bp overlap
HDAC1 1 dataset
ChIP NB4 GSE126720.HDAC1.NB4 200 bp overlap
HDAC2 1 dataset
ChIP K-562 ENCSR000BMG.HDAC2.K-562 130 bp overlap
HESX1 1 dataset
Motif DE_48h DE_48h-HESX1_MA0894.2 6 bp overlap
HMBOX1 3 datasets
ChIP K-562 ENCSR757IIU.HMBOX1.K-562 231 bp overlap
ChIP K562 ENCFF055GAZ 452 bp overlap
ChIP K562 ENCFF317JJX 447 bp overlap
HOXA7 1 dataset
Motif DE_48h DE_48h-HOXA7_MA1498.3 6 bp overlap
IKZF1 2 datasets
ChIP K-562 ENCSR395HWC.IKZF1.K-562 603 bp overlap
ChIP K562 ENCFF771OHZ 497 bp overlap
ISL2 1 dataset
Motif DE_48h DE_48h-ISL2_MA0914.2 6 bp overlap
JMJD1C 1 dataset
ChIP NB4 GSE63484.JMJD1C.NB4 140 bp overlap
JUN 1 dataset
ChIP DE_D2 S02-DE-d2-JUN-exp1 365 bp overlap
JUNB 1 dataset
Motif DE_48h DE_48h-JUNB_MA0490.3 9 bp overlap
JUND 2 datasets
Motif DE_48h DE_48h-JUND_MA0491.3 9 bp overlap
ChIP K-562 ENCSR000EGN.JUND.K-562 169 bp overlap
Jun 1 dataset
Motif DE_48h DE_48h-Jun_MA0489.3 8 bp overlap
KDM1A 4 datasets
ChIP NB4_DMSO GSE128528.KDM1A.NB4_DMSO 216 bp overlap
ChIP SH-SY5Y_B3 GSE58258.KDM1A.SH-SY5Y_B3 164 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.KDM1A.pancreatic-progenitor_PP1 350 bp overlap
ChIP pancreatic-progenitor_PP2-KDM1A-inh GSE104840.KDM1A.pancreatic-progenitor_PP2-KDM1A-inh 326 bp overlap
LBX2 1 dataset
Motif DE_48h DE_48h-LBX2_MA0699.2 6 bp overlap
LDB1 1 dataset
ChIP K-562 GSE142227.LDB1.K-562 144 bp overlap
LHX2 1 dataset
Motif DE_48h DE_48h-LHX2_MA0700.3 6 bp overlap
MAFK 1 dataset
Motif DE_48h DE_48h-MAFK_MA0496.4 10 bp overlap
MED1 1 dataset
ChIP HUVEC-C_siERG GSE124892.MED1.HUVEC-C_siERG 275 bp overlap
MSX1 1 dataset
Motif DE_48h DE_48h-MSX1_MA0666.3 6 bp overlap
MSX2 1 dataset
Motif DE_48h DE_48h-MSX2_MA0708.3 6 bp overlap
MYB 1 dataset
ChIP Jurkat GSE59657.MYB.Jurkat 225 bp overlap
MYCN 1 dataset
ChIP Kelly GSE94822.MYCN.Kelly 158 bp overlap
Mafg 1 dataset
Motif DE_48h DE_48h-Mafg_MA0659.4 12 bp overlap
Msx3 1 dataset
Motif DE_48h DE_48h-Msx3_MA0709.2 6 bp overlap
NFYB 1 dataset
ChIP K-562 GSE26439.NFYB.K-562 188 bp overlap
NR2F2 1 dataset
ChIP K-562 ENCSR000BRS.NR2F2.K-562 130 bp overlap
NR2F6 2 datasets
ChIP K-562 ENCSR707QWA.NR2F6.K-562 163 bp overlap
ChIP K562 ENCFF674RQA 401 bp overlap
NR3C1 1 dataset
ChIP MDA-MB-453 GSE152203.NR3C1.MDA-MB-453 220 bp overlap
Nkx3-1 1 dataset
Motif DE_48h DE_48h-Nkx3-1_MA0124.3 7 bp overlap
Nkx3-2 1 dataset
Motif DE_48h DE_48h-Nkx3-2_MA0122.4 10 bp overlap
Nobox 1 dataset
Motif DE_48h DE_48h-Nobox_MA0125.2 6 bp overlap
ONECUT1 2 datasets
ChIP H9 ERP004206.ONECUT1.H9 189 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.ONECUT1.pancreatic-progenitor_PP1 371 bp overlap
ONECUT2 1 dataset
ChIP AGS_Overexpression GSE113045.ONECUT2.AGS_Overexpression 197 bp overlap
PML 1 dataset
ChIP NB4 GSE126720.PML.NB4 138 bp overlap
POLR2A 1 dataset
ChIP stomach ENCFF820WZN 125 bp overlap
RAX 1 dataset
Motif DE_48h DE_48h-RAX_MA0718.2 6 bp overlap
RCOR1 1 dataset
ChIP keratinocyte_diff GSE57702.RCOR1.keratinocyte_diff 204 bp overlap
RELA 1 dataset
ChIP HAEC_TNFa_4h GSE89970.RELA.HAEC_TNFa_4h 239 bp overlap
REST 1 dataset
ChIP K-562 ENCSR000BMW.REST.K-562 155 bp overlap
RUNX2 1 dataset
ChIP LNCaP-C4-2B GSE33889.RUNX2.LNCaP-C4-2B 345 bp overlap
RXR 1 dataset
ChIP LS180_125 GSE31939.RXR.LS180_125 121 bp overlap
SKI 2 datasets
ChIP HL-60 GSE107553.SKI.HL-60 100 bp overlap
ChIP HL-60_CRISPRCas9_ctrl GSE107553.SKI.HL-60_CRISPRCas9_ctrl 251 bp overlap
SMAD2 1 dataset
ChIP endoderm GSE29422.SMAD2.endoderm 184 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 400 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 472 bp overlap
SMAD2_3 3 datasets
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 282 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 356 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 367 bp overlap
SMAD3 1 dataset
ChIP endoderm GSE29422.SMAD3.endoderm 198 bp overlap
SMAD4 1 dataset
ChIP Caco-2 GSE112946.SMAD4.Caco-2 217 bp overlap
SMARCA4 1 dataset
ChIP K-562 ENCSR587OQL.SMARCA4.K-562 306 bp overlap
SMARCE1 1 dataset
ChIP K-562 ENCSR157TCS.SMARCE1.K-562 307 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 242 bp overlap
SPI1 2 datasets
ChIP K-562_NABUT GSE74999.SPI1.K-562_NABUT 144 bp overlap
ChIP primary-neutrophil_donorE GSE128834.SPI1.primary-neutrophil_donorE 97 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 203 bp overlap
TAL1 6 datasets
ChIP K-562 GSE107726.TAL1.K-562 276 bp overlap
ChIP K-562 ENCSR000EHB.TAL1.K-562 121 bp overlap
ChIP K-562_dCas9-KRAB GSE132212.TAL1.K-562_dCas9-KRAB 191 bp overlap
ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 186 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 234 bp overlap
ChIP ProEs GSE59087.TAL1.ProEs 172 bp overlap
TCF12 2 datasets
ChIP K-562 ENCSR744WOO.TCF12.K-562 299 bp overlap
ChIP K562 ENCFF931DJY 359 bp overlap
TCF3 3 datasets
ChIP K-562 ENCSR970OJY.TCF3.K-562 212 bp overlap
ChIP K562 ENCFF319QZT 356 bp overlap
ChIP Kasumi-1 GSE43834.TCF3.Kasumi-1 217 bp overlap
TEAD4 1 dataset
ChIP K562 ENCFF673NIK 349 bp overlap
TFAP2A 1 dataset
ChIP WA09 GSE105081.TFAP2A.WA09 303 bp overlap
TFAP2C 1 dataset
ChIP WA09 GSE105081.TFAP2C.WA09 176 bp overlap
ZBTB7A 1 dataset
ChIP HUDEP-2 GSE103445.ZBTB7A.HUDEP-2 315 bp overlap
ZEB1 2 datasets
Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap
Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap
ZFX 1 dataset
ChIP K562 ENCFF169LZT 433 bp overlap
ZNF24 3 datasets
ChIP K-562 ENCSR695EQB.ZNF24.K-562 346 bp overlap
ChIP K-562 ENCSR099NCH.ZNF24.K-562 345 bp overlap
ChIP K562 ENCFF615YYW 611 bp overlap
ZNF524 1 dataset
Motif DE_48h DE_48h-ZNF524_MA2096.1 9 bp overlap
ZNF750 1 dataset
ChIP keratinocyte_diff GSE57702.ZNF750.keratinocyte_diff 483 bp overlap
ZNF766 1 dataset
Motif DE_48h DE_48h-ZNF766_MA2098.1 9 bp overlap
Zfx 1 dataset
Motif DE_48h DE_48h-Zfx_MA0146.3 10 bp overlap
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