chr6 : 121,618,730 – 121,619,458
728 bp 120 TFs 3 linked genes
This 728 bp open chromatin element is linked to ENSG00000290064, GJA1, and TBC1D32 and is bound by 120 transcription factors.
Linked Genes
3 genes
Distance
Link type
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ENSG00000290064 6.5 kb Proximal Proximity
GJA1 183.5 kb Distal Multiome+HiCAR
TBC1D32 284.4 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr6:121,613,730 – 121,624,458
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
120 transcription factors
Source
Cell type
ATF2 2 datasets
Motif DE_12h DE_12h-ATF2_MA1632.2 10 bp overlap
Motif ES_0h ES_0h-ATF2_MA1632.2 10 bp overlap
ATF4 2 datasets
Motif DE_12h DE_12h-ATF4_MA0833.3 10 bp overlap
Motif ES_0h ES_0h-ATF4_MA0833.3 10 bp overlap
Arid3a 1 dataset
Motif ES_0h ES_0h-Arid3a_MA0151.1 6 bp overlap
BACH2 2 datasets
Motif DE_12h DE_12h-BACH2_MA1470.2 19 bp overlap
Motif ES_0h ES_0h-BACH2_MA1470.2 19 bp overlap
CHD7 2 datasets
ChIP H1 ENCFF126NLU 425 bp overlap
ChIP WA01 ENCSR000AVA.CHD7.WA01 205 bp overlap
CREB1 4 datasets
Motif DE_12h DE_12h-CREB1_MA0018.5 8 bp overlap
Motif ES_0h ES_0h-CREB1_MA0018.5 8 bp overlap
ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 153 bp overlap
ChIP WA01 ENCSR000BSN.CREB1.WA01 137 bp overlap
Dmrt1 1 dataset
Motif ES_0h ES_0h-Dmrt1_MA1603.2 9 bp overlap
EGR4 1 dataset
Motif ES_0h ES_0h-EGR4_MA0733.2 11 bp overlap
EOMES 1 dataset
Motif ES_0h ES_0h-EOMES_MA0800.2 9 bp overlap
EP300 1 dataset
ChIP hESC GSE17917.EP300.hESC 297 bp overlap
EWSR1-FLI1 1 dataset
Motif ES_0h ES_0h-EWSR1-FLI1_MA0149.1 18 bp overlap
FEZF2 2 datasets
Motif DE_12h DE_12h-FEZF2_MA2341.1 8 bp overlap
Motif ES_0h ES_0h-FEZF2_MA2341.1 8 bp overlap
FOSL2::JUN 2 datasets
Motif DE_12h DE_12h-FOSL2JUN_MA1131.2 10 bp overlap
Motif ES_0h ES_0h-FOSL2JUN_MA1131.2 10 bp overlap
FOXA1 1 dataset
Motif ES_0h ES_0h-FOXA1_MA0148.5 8 bp overlap
FOXE1 1 dataset
Motif ES_0h ES_0h-FOXE1_MA1487.3 12 bp overlap
FOXP4 1 dataset
ChIP WTC11 ENCFF708TAF 331 bp overlap
GLI3 1 dataset
Motif ES_0h ES_0h-GLI3_MA1491.3 15 bp overlap
Gli1 1 dataset
Motif ES_0h ES_0h-Gli1_MA1990.2 10 bp overlap
Gli2 1 dataset
Motif ES_0h ES_0h-Gli2_MA0734.4 9 bp overlap
HIC2 2 datasets
Motif DE_12h DE_12h-HIC2_MA0738.2 6 bp overlap
Motif ES_0h ES_0h-HIC2_MA0738.2 6 bp overlap
HOXB4 1 dataset
Motif ES_0h ES_0h-HOXB4_MA1499.2 6 bp overlap
HOXC4 1 dataset
Motif ES_0h ES_0h-HOXC4_MA1504.2 6 bp overlap
HOXD4 1 dataset
Motif ES_0h ES_0h-HOXD4_MA1507.2 6 bp overlap
Hic1 1 dataset
Motif ES_0h ES_0h-Hic1_MA0739.2 8 bp overlap
Hmga1 1 dataset
Motif ES_0h ES_0h-Hmga1_MA2124.1 8 bp overlap
Hnf1A 1 dataset
Motif ES_0h ES_0h-Hnf1A_MA1991.2 10 bp overlap
Irf1 2 datasets
Motif DE_12h DE_12h-Irf1_MA0050.4 11 bp overlap
Motif ES_0h ES_0h-Irf1_MA0050.4 11 bp overlap
JUN 5 datasets
Motif DE_12h DE_12h-JUN_MA0488.2 10 bp overlap
ChIP DE_D1 S40-DE-d1-JUN-exp2 404 bp overlap
ChIP ESC S34-ESC-d0-JUN-exp2 360 bp overlap
Motif ES_0h ES_0h-JUN_MA0488.2 10 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 311 bp overlap
KLF4 2 datasets
ChIP WA09 GSE105028.KLF4.WA09 341 bp overlap
ChIP hiPSC GSE56567.KLF4.hiPSC 329 bp overlap
KLF6 1 dataset
Motif ES_0h ES_0h-KLF6_MA1517.2 9 bp overlap
KLF9 1 dataset
Motif ES_0h ES_0h-KLF9_MA1107.3 11 bp overlap
Lhx3 1 dataset
Motif ES_0h ES_0h-Lhx3_MA0135.2 12 bp overlap
MAFF 2 datasets
Motif DE_12h DE_12h-MAFF_MA0495.4 11 bp overlap
Motif ES_0h ES_0h-MAFF_MA0495.4 11 bp overlap
MED1 1 dataset
ChIP hESC_PRIMED GSE69646.MED1.hESC_PRIMED 728 bp overlap
MEIS1 1 dataset
Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap
MGA 1 dataset
Motif ES_0h ES_0h-MGA_MA0801.1 8 bp overlap
Msgn1 2 datasets
Motif DE_12h DE_12h-Msgn1_MA1524.3 10 bp overlap
Motif ES_0h ES_0h-Msgn1_MA1524.3 10 bp overlap
NANOG 8 datasets
ChIP GM23338 ENCFF065NZG 311 bp overlap
ChIP GM23338 ENCSR061DGF.NANOG.GM23338 348 bp overlap
ChIP HUES-8 GSE109524.NANOG.HUES-8 460 bp overlap
ChIP WA01 ERP004238.NANOG.WA01 425 bp overlap
ChIP WA09 GSE105028.NANOG.WA09 624 bp overlap
ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 495 bp overlap
ChIP hESC GSE20650.NANOG.hESC 236 bp overlap
ChIP hESC GSE18292.NANOG.hESC 197 bp overlap
NFIA 1 dataset
Motif ES_0h ES_0h-NFIA_MA0670.2 6 bp overlap
NFIX 1 dataset
Motif ES_0h ES_0h-NFIX_MA0671.2 6 bp overlap
NFKB1 1 dataset
ChIP L1236 GSE63736.NFKB1.L1236 177 bp overlap
NFKB2 1 dataset
ChIP L1236 GSE63736.NFKB2.L1236 95 bp overlap
NFYB 1 dataset
Motif DE_12h DE_12h-NFYB_MA0502.3 9 bp overlap
NIPBL 2 datasets
ChIP WA09 GSE105028.NIPBL.WA09 333 bp overlap
ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 243 bp overlap
NKX6-1 1 dataset
Motif ES_0h ES_0h-NKX6-1_MA0674.2 7 bp overlap
NR2C1 2 datasets
Motif DE_12h DE_12h-NR2C1_MA1535.2 6 bp overlap
Motif ES_0h ES_0h-NR2C1_MA1535.2 6 bp overlap
NR2C2 2 datasets
Motif DE_12h DE_12h-NR2C2_MA1536.2 6 bp overlap
Motif ES_0h ES_0h-NR2C2_MA1536.2 6 bp overlap
NR2F1 2 datasets
Motif DE_12h DE_12h-NR2F1_MA0017.3 12 bp overlap
Motif ES_0h ES_0h-NR2F1_MA0017.3 12 bp overlap
Nr1H2 2 datasets
Motif DE_12h DE_12h-Nr1H2_MA1996.2 6 bp overlap
Motif ES_0h ES_0h-Nr1H2_MA1996.2 6 bp overlap
Nr1H4 2 datasets
Motif DE_12h DE_12h-Nr1H4_MA1110.3 6 bp overlap
Motif ES_0h ES_0h-Nr1H4_MA1110.3 6 bp overlap
Nr1h3 2 datasets
Motif DE_12h DE_12h-Nr1h3_MA2337.1 6 bp overlap
Motif ES_0h ES_0h-Nr1h3_MA2337.1 6 bp overlap
Nr2F6 1 dataset
Motif ES_0h ES_0h-Nr2F6_MA0728.1 15 bp overlap
PHOX2B 3 datasets
Motif ES_0h ES_0h-PHOX2B_MA0681.3 12 bp overlap
Motif ES_0h ES_0h-PHOX2B_MA0681.3 12 bp overlap
Motif ES_0h ES_0h-PHOX2B_MA0681.3 12 bp overlap
POLR2A 1 dataset
ChIP H1 ENCFF566JSR 631 bp overlap
POU1F1 1 dataset
Motif ES_0h ES_0h-POU1F1_MA0784.3 14 bp overlap
POU2F1 1 dataset
Motif ES_0h ES_0h-POU2F1_MA0785.2 9 bp overlap
POU2F1::SOX2 1 dataset
Motif ES_0h ES_0h-POU2F1SOX2_MA1962.1 17 bp overlap
POU2F2 1 dataset
Motif ES_0h ES_0h-POU2F2_MA0507.3 13 bp overlap
POU3F1 1 dataset
Motif ES_0h ES_0h-POU3F1_MA0786.2 10 bp overlap
POU3F2 1 dataset
Motif ES_0h ES_0h-POU3F2_MA0787.1 12 bp overlap
POU3F3 1 dataset
Motif ES_0h ES_0h-POU3F3_MA0788.1 13 bp overlap
POU3F4 1 dataset
Motif ES_0h ES_0h-POU3F4_MA0789.1 9 bp overlap
POU5F1 7 datasets
ChIP BJ_INDUCED GSE36570.POU5F1.BJ_INDUCED 115 bp overlap
ChIP GM23338 ENCFF333SNB 311 bp overlap
ChIP HUES-8 GSE109524.POU5F1.HUES-8 564 bp overlap
ChIP hESC ENCSR264RJX.POU5F1.hESC 247 bp overlap
ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 318 bp overlap
ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 726 bp overlap
ChIP hiPSC GSE56567.POU5F1.hiPSC 192 bp overlap
POU5F1B 1 dataset
Motif ES_0h ES_0h-POU5F1B_MA0792.1 9 bp overlap
PRDM1 2 datasets
Motif DE_12h DE_12h-PRDM1_MA0508.4 7 bp overlap
Motif ES_0h ES_0h-PRDM1_MA0508.4 7 bp overlap
PROP1 2 datasets
Motif ES_0h ES_0h-PROP1_MA0715.1 11 bp overlap
Motif ES_0h ES_0h-PROP1_MA0715.1 11 bp overlap
Pparg::Rxra 1 dataset
Motif ES_0h ES_0h-PpargRxra_MA0065.3 13 bp overlap
RARA 2 datasets
Motif DE_12h DE_12h-RARA_MA0730.1 17 bp overlap
Motif ES_0h ES_0h-RARA_MA0730.1 17 bp overlap
RARA::RXRA 2 datasets
Motif DE_12h DE_12h-RARARXRA_MA0159.1 17 bp overlap
Motif ES_0h ES_0h-RARARXRA_MA0159.1 17 bp overlap
RARA::RXRG 2 datasets
Motif DE_12h DE_12h-RARARXRG_MA1149.2 17 bp overlap
Motif ES_0h ES_0h-RARARXRG_MA1149.2 17 bp overlap
RBBP5 1 dataset
ChIP WA01 ENCSR000AQC.RBBP5.WA01 135 bp overlap
REL 1 dataset
Motif ES_0h ES_0h-REL_MA0101.1 10 bp overlap
RELA 1 dataset
Motif ES_0h ES_0h-RELA_MA0107.1 10 bp overlap
Rarb 3 datasets
Motif DE_12h DE_12h-Rarb_MA0858.1 17 bp overlap
Motif ES_0h ES_0h-Rarb_MA0857.1 16 bp overlap
Motif ES_0h ES_0h-Rarb_MA0858.1 17 bp overlap
SALL3 1 dataset
ChIP hiPSC GSE104863.SALL3.hiPSC 231 bp overlap
SIX1 1 dataset
Motif DE_12h DE_12h-SIX1_MA1118.2 9 bp overlap
SMAD2 1 dataset
Motif ES_0h ES_0h-SMAD2_MA1964.2 6 bp overlap
SMAD3 1 dataset
ChIP BG03 GSE21614.SMAD3.BG03 177 bp overlap
SMARCA4 1 dataset
ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 247 bp overlap
SMARCC1 1 dataset
ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 256 bp overlap
SOX10 1 dataset
Motif ES_0h ES_0h-SOX10_MA0442.3 6 bp overlap
SOX2 2 datasets
ChIP HNSC GSE69479.SOX2.HNSC 163 bp overlap
ChIP hiPSC GSE56567.SOX2.hiPSC 431 bp overlap
SOX4 1 dataset
Motif ES_0h ES_0h-SOX4_MA0867.3 8 bp overlap
SOX8 1 dataset
Motif ES_0h ES_0h-SOX8_MA0868.3 7 bp overlap
SP1 1 dataset
ChIP H1 ENCFF263FUH 321 bp overlap
SP5 2 datasets
Motif ES_0h ES_0h-SP5_MA1965.2 6 bp overlap
Motif ES_0h ES_0h-SP5_MA1965.2 6 bp overlap
SPI1 2 datasets
ChIP CTV-1_FLAG_15perc GSE128835.SPI1.CTV-1_FLAG_15perc 167 bp overlap
ChIP primary-monocyte_donorA_ncMO GSE128834.SPI1.primary-monocyte_donorA_ncMO 84 bp overlap
SPIB 2 datasets
Motif DE_12h DE_12h-SPIB_MA0081.3 13 bp overlap
Motif ES_0h ES_0h-SPIB_MA0081.3 13 bp overlap
SPIC 1 dataset
Motif ES_0h ES_0h-SPIC_MA0687.2 13 bp overlap
SRY 1 dataset
Motif ES_0h ES_0h-SRY_MA0084.2 7 bp overlap
Six4 1 dataset
Motif DE_12h DE_12h-Six4_MA2001.2 7 bp overlap
Sox11 3 datasets
Motif DE_12h DE_12h-Sox11_MA0869.3 8 bp overlap
Motif ES_0h ES_0h-Sox11_MA0869.3 8 bp overlap
Motif ES_0h ES_0h-Sox11_MA0869.3 8 bp overlap
Sox17 3 datasets
Motif DE_12h DE_12h-Sox17_MA0078.3 10 bp overlap
Motif ES_0h ES_0h-Sox17_MA0078.3 10 bp overlap
Motif ES_0h ES_0h-Sox17_MA0078.3 10 bp overlap
Sox5 2 datasets
Motif ES_0h ES_0h-Sox5_MA0087.3 8 bp overlap
Motif ES_0h ES_0h-Sox5_MA0087.3 8 bp overlap
Sox6 3 datasets
Motif DE_12h DE_12h-Sox6_MA0515.1 10 bp overlap
Motif ES_0h ES_0h-Sox6_MA0515.1 10 bp overlap
Motif ES_0h ES_0h-Sox6_MA0515.1 10 bp overlap
Sox7 3 datasets
Motif DE_12h DE_12h-Sox7_MA2095.1 10 bp overlap
Motif ES_0h ES_0h-Sox7_MA2095.1 10 bp overlap
Motif ES_0h ES_0h-Sox7_MA2095.1 10 bp overlap
Spi1 2 datasets
Motif DE_12h DE_12h-Spi1_MA0080.7 13 bp overlap
Motif ES_0h ES_0h-Spi1_MA0080.7 13 bp overlap
TAF1 2 datasets
ChIP H1 ENCFF478SZO 485 bp overlap
ChIP WA01 ENCSR000BHO.TAF1.WA01 183 bp overlap
TAF7 1 dataset
ChIP H1 ENCFF061XZZ 337 bp overlap
TBP 3 datasets
ChIP hESC GSE122298.TBP.hESC 149 bp overlap
ChIP hESC_10h GSE122298.TBP.hESC_10h 140 bp overlap
ChIP hESC_2h GSE122298.TBP.hESC_2h 326 bp overlap
TBR1 1 dataset
Motif ES_0h ES_0h-TBR1_MA0802.2 9 bp overlap
TBX1 1 dataset
Motif ES_0h ES_0h-TBX1_MA0805.1 8 bp overlap
TBX15 1 dataset
Motif ES_0h ES_0h-TBX15_MA0803.1 8 bp overlap
TBX4 1 dataset
Motif ES_0h ES_0h-TBX4_MA0806.1 8 bp overlap
TCF3 1 dataset
ChIP NPC GSE154479.TCF3.NPC 301 bp overlap
THAP1 1 dataset
Motif ES_0h ES_0h-THAP1_MA0597.3 8 bp overlap
THRB 2 datasets
Motif DE_12h DE_12h-THRB_MA1576.2 18 bp overlap
Motif ES_0h ES_0h-THRB_MA1576.2 18 bp overlap
Tfcp2l1 1 dataset
Motif ES_0h ES_0h-Tfcp2l1_MA0145.2 14 bp overlap
Wt1 1 dataset
Motif ES_0h ES_0h-Wt1_MA1627.2 10 bp overlap
ZNF16 1 dataset
Motif DE_12h DE_12h-ZNF16_MA1654.2 21 bp overlap
ZNF214 3 datasets
Motif DE_12h DE_12h-ZNF214_MA1975.2 13 bp overlap
Motif ES_0h ES_0h-ZNF214_MA1975.2 13 bp overlap
Motif ES_0h ES_0h-ZNF214_MA1975.2 13 bp overlap
ZNF263 1 dataset
Motif ES_0h ES_0h-ZNF263_MA0528.3 7 bp overlap
ZNF274 1 dataset
Motif ES_0h ES_0h-ZNF274_MA1592.2 12 bp overlap
ZNF449 2 datasets
Motif DE_12h DE_12h-ZNF449_MA1656.2 10 bp overlap
Motif ES_0h ES_0h-ZNF449_MA1656.2 10 bp overlap
ZNF462 2 datasets
ChIP GM23338 ENCFF896CCA 251 bp overlap
ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 322 bp overlap
ZNF669 2 datasets
Motif DE_12h DE_12h-ZNF669_MA1985.1 15 bp overlap
Motif ES_0h ES_0h-ZNF669_MA1985.1 15 bp overlap
ZNF675 2 datasets
Motif DE_12h DE_12h-ZNF675_MA1714.2 19 bp overlap
Motif ES_0h ES_0h-ZNF675_MA1714.2 19 bp overlap
ZNF701 1 dataset
Motif ES_0h ES_0h-ZNF701_MA1987.2 17 bp overlap
ZSCAN4 1 dataset
Motif ES_0h ES_0h-ZSCAN4_MA1155.1 15 bp overlap
Znf423 1 dataset
Motif ES_0h ES_0h-Znf423_MA0116.1 15 bp overlap
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