chr3 : 176,988,787 – 176,989,317
530 bp 94 TFs 1 linked gene
This 530 bp open chromatin element is linked to TBL1XR1 and is bound by 94 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
TBL1XR1 208.2 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr3:176,983,787 – 176,994,317
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
94 transcription factors
Source
Cell type
ARID1B 2 datasets
ChIP K-562 ENCSR822CCM.ARID1B.K-562 239 bp overlap
ChIP K562 ENCFF938UXQ 438 bp overlap
BRD4 2 datasets
ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 215 bp overlap
ChIP RH4_shscr GSE140115.BRD4.RH4_shscr 252 bp overlap
Bcl11B 1 dataset
Motif DE_48h DE_48h-Bcl11B_MA1989.2 9 bp overlap
CBFA2T3 2 datasets
ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 307 bp overlap
ChIP K562 ENCFF673OEZ 387 bp overlap
CEBPD 1 dataset
ChIP K-562 ENCSR000BVY.CEBPD.K-562 120 bp overlap
CREM 1 dataset
ChIP K-562 ENCSR077DKV.CREM.K-562 185 bp overlap
Crx 1 dataset
Motif DE_48h DE_48h-Crx_MA0467.3 6 bp overlap
EBF1 1 dataset
Motif DE_48h DE_48h-EBF1_MA0154.5 11 bp overlap
EBF3 1 dataset
Motif DE_48h DE_48h-EBF3_MA1637.2 9 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 168 bp overlap
EP300 1 dataset
ChIP neural cell ENCFF442QNK 156 bp overlap
ERG 1 dataset
ChIP Jurkat GSE49091.ERG.Jurkat 193 bp overlap
ESR1 3 datasets
ChIP Ishikawa_C1-12 GSE147141.ESR1.Ishikawa_C1-12 72 bp overlap
ChIP Ishikawa_E2_D538G_clone2 GSE132426.ESR1.Ishikawa_E2_D538G_clone2 151 bp overlap
ChIP Ishikawa_E2_clone2 GSE132426.ESR1.Ishikawa_E2_clone2 53 bp overlap
EWSR1-FLI1 1 dataset
Motif DE_60h DE_60h-EWSR1-FLI1_MA0149.1 18 bp overlap
EZH1 1 dataset
ChIP ProEs GSE59087.EZH1.ProEs 186 bp overlap
Ebf2 1 dataset
Motif DE_48h DE_48h-Ebf2_MA1604.2 9 bp overlap
Ebf4 1 dataset
Motif DE_48h DE_48h-Ebf4_MA2122.1 11 bp overlap
FEZF1 3 datasets
ChIP HEK293 ENCFF528YED 427 bp overlap
ChIP HEK293 GSE76494.FEZF1.HEK293 143 bp overlap
ChIP HEK293 ENCSR827NWO.FEZF1.HEK293 334 bp overlap
FEZF2 1 dataset
Motif DE_48h DE_48h-FEZF2_MA2341.1 8 bp overlap
FOSL2 1 dataset
Motif DE_48h DE_48h-FOSL2_MA0478.2 10 bp overlap
FOXA2 1 dataset
ChIP DE DE-FOXA2-1 255 bp overlap
GATA1 7 datasets
ChIP CD34_ERYTH_BMP GSE29194.GATA1.CD34_ERYTH_BMP 186 bp overlap
ChIP HUDEP-2_30min GSE104676.GATA1.HUDEP-2_30min 177 bp overlap
ChIP K-562 GSE107726.GATA1.K-562 293 bp overlap
ChIP K-562 ENCSR000EFT.GATA1.K-562 143 bp overlap
ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 240 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 225 bp overlap
ChIP K562 ENCFF094CMK 251 bp overlap
GATA2 8 datasets
ChIP CD34_ACY957 GSE60792.GATA2.CD34_ACY957 225 bp overlap
Motif DE_36h DE_36h-GATA2_MA0036.4 7 bp overlap
Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap
Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap
ChIP K-562 ENCSR000DKA.GATA2.K-562 293 bp overlap
ChIP K562 ENCFF830LLA 475 bp overlap
ChIP ME-1_CBFB-MYH11-KD GSE117138.GATA2.ME-1_CBFB-MYH11-KD 294 bp overlap
ChIP TF1 GSE73207.GATA2.TF1 361 bp overlap
GATA3 4 datasets
ChIP Jurkat GSE76181.GATA3.Jurkat 236 bp overlap
ChIP Kelly GSE65664.GATA3.Kelly 275 bp overlap
ChIP Kelly GSE94822.GATA3.Kelly 178 bp overlap
ChIP SK-N-BE2-C GSE94822.GATA3.SK-N-BE2-C 183 bp overlap
GATA4 9 datasets
ChIP DE DE-GATA4-1 442 bp overlap
ChIP DE DE-GATA4-2 524 bp overlap
Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
ChIP Hep-G2 GSE135714.GATA4.Hep-G2 385 bp overlap
ChIP foregut GSE117136.GATA4.foregut 449 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 458 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 454 bp overlap
GATA5 4 datasets
Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
GATA6 22 datasets
ChIP AGS GSE51705.GATA6.AGS 373 bp overlap
ChIP AGS GSE51936.GATA6.AGS 79 bp overlap
ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 262 bp overlap
ChIP DE DE-GATA6-1 428 bp overlap
ChIP DE DE-GATA6-2 530 bp overlap
Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 342 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 442 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 440 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 398 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 305 bp overlap
ChIP PATU8988 GSE47535.GATA6.PATU8988 214 bp overlap
ChIP YCC-3 GSE51705.GATA6.YCC-3 160 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 441 bp overlap
ChIP foregut GSE117136.GATA6.foregut 484 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 404 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 446 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 449 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 353 bp overlap
GSC 1 dataset
Motif DE_48h DE_48h-GSC_MA0648.2 6 bp overlap
GSC2 1 dataset
Motif DE_48h DE_48h-GSC2_MA0891.2 6 bp overlap
Gata3 4 datasets
Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
HAND2 2 datasets
ChIP Kelly GSE94822.HAND2.Kelly 111 bp overlap
ChIP SK-N-BE2-C GSE94822.HAND2.SK-N-BE2-C 342 bp overlap
HDAC1 2 datasets
ChIP K-562 ENCSR387UWP.HDAC1.K-562 345 bp overlap
ChIP K562 ENCFF968WBH 223 bp overlap
HDAC2 2 datasets
ChIP K-562 ENCSR893WSB.HDAC2.K-562 194 bp overlap
ChIP K562 ENCFF744ALD 416 bp overlap
HIC2 1 dataset
Motif DE_48h DE_48h-HIC2_MA0738.2 6 bp overlap
HNF4A 1 dataset
ChIP Caco-2_DIFF GSE23436.HNF4A.Caco-2_DIFF 118 bp overlap
ISL1 1 dataset
ChIP SK-N-BE2-C GSE94822.ISL1.SK-N-BE2-C 244 bp overlap
JUND 3 datasets
Motif DE_36h DE_36h-JUND_MA0492.2 11 bp overlap
Motif DE_48h DE_48h-JUND_MA0492.2 11 bp overlap
Motif DE_60h DE_60h-JUND_MA0492.2 11 bp overlap
KDM1A 4 datasets
ChIP K-562 ENCSR360HRA.KDM1A.K-562 231 bp overlap
ChIP K-562 ENCSR908CMW.KDM1A.K-562 240 bp overlap
ChIP K562 ENCFF133OLU 444 bp overlap
ChIP pancreatic-progenitor_PP2-KDM1A-inh GSE104840.KDM1A.pancreatic-progenitor_PP2-KDM1A-inh 345 bp overlap
LDB1 1 dataset
ChIP HEP GSE52637.LDB1.HEP 117 bp overlap
LMO1 1 dataset
ChIP Jurkat GSE94391.LMO1.Jurkat 282 bp overlap
MAX 1 dataset
ChIP NCI-H2171 GSE36354.MAX.NCI-H2171 227 bp overlap
MTA2 1 dataset
ChIP RH4 GSE155861.MTA2.RH4 306 bp overlap
MYB 2 datasets
ChIP DU528 GSE94000.MYB.DU528 343 bp overlap
ChIP Jurkat GSE59657.MYB.Jurkat 251 bp overlap
MYC 1 dataset
ChIP NCI-H2171 GSE36354.MYC.NCI-H2171 183 bp overlap
MYCN 1 dataset
ChIP Kelly GSE94822.MYCN.Kelly 281 bp overlap
Mecom 3 datasets
Motif DE_36h DE_36h-Mecom_MA0029.2 11 bp overlap
Motif DE_48h DE_48h-Mecom_MA0029.2 11 bp overlap
Motif DE_60h DE_60h-Mecom_MA0029.2 11 bp overlap
NFE2 1 dataset
ChIP ProEs GSE59087.NFE2.ProEs 114 bp overlap
NKX2-1 1 dataset
ChIP NCI-H1819 GSE39998.NKX2-1.NCI-H1819 303 bp overlap
NR2F2 2 datasets
ChIP K-562 ENCSR000BRS.NR2F2.K-562 196 bp overlap
ChIP K562 ENCFF004YPK 391 bp overlap
NR2F6 1 dataset
ChIP K-562 ENCSR707QWA.NR2F6.K-562 155 bp overlap
Nr2e3 2 datasets
Motif DE_48h DE_48h-Nr2e3_MA0164.2 6 bp overlap
Motif DE_60h DE_60h-Nr2e3_MA0164.2 6 bp overlap
OTX1 1 dataset
Motif DE_48h DE_48h-OTX1_MA0711.2 6 bp overlap
PAX3-FOXO1 1 dataset
ChIP RH4 GSE140115.PAX3-FOXO1.RH4 282 bp overlap
PDX1 2 datasets
ChIP hiPSC GSE125768.PDX1.hiPSC 223 bp overlap
ChIP hiPSC_derived_PPs GSE106949.PDX1.hiPSC_derived_PPs 183 bp overlap
PGR 1 dataset
ChIP T-47D GSE31129.PGR.T-47D 170 bp overlap
PITX1 1 dataset
Motif DE_48h DE_48h-PITX1_MA0682.3 6 bp overlap
PITX3 1 dataset
Motif DE_48h DE_48h-PITX3_MA0714.2 6 bp overlap
RCOR1 1 dataset
ChIP K562 ENCFF216EEJ 297 bp overlap
REST 1 dataset
ChIP neural cell ENCFF882LXX 85 bp overlap
RHOXF1 1 dataset
Motif DE_48h DE_48h-RHOXF1_MA0719.2 6 bp overlap
RNF2 2 datasets
ChIP K-562 ENCSR138FUZ.RNF2.K-562 134 bp overlap
ChIP ME-1_KD GSE128771.RNF2.ME-1_KD 224 bp overlap
RUNX1 3 datasets
ChIP Jurkat GSE76181.RUNX1.Jurkat 183 bp overlap
ChIP ME-1_CBFB-MYH11-KD GSE117138.RUNX1.ME-1_CBFB-MYH11-KD 330 bp overlap
ChIP ME-1_Con GSE128771.RUNX1.ME-1_Con 330 bp overlap
RUNX2 3 datasets
Motif DE_48h DE_48h-RUNX2_MA0511.2 9 bp overlap
ChIP LNCaP-C4-2B GSE33889.RUNX2.LNCaP-C4-2B 284 bp overlap
ChIP PER-117 GSE151819.RUNX2.PER-117 280 bp overlap
RUNX3 4 datasets
Motif DE_36h DE_36h-RUNX3_MA0684.3 8 bp overlap
Motif DE_48h DE_48h-RUNX3_MA0684.3 8 bp overlap
Motif DE_48h DE_48h-RUNX3_MA0684.3 8 bp overlap
Motif DE_60h DE_60h-RUNX3_MA0684.3 8 bp overlap
Runx1 1 dataset
Motif DE_48h DE_48h-Runx1_MA0002.3 9 bp overlap
SETDB1 2 datasets
ChIP HEK293 ENCSR348AGV.SETDB1.HEK293 94 bp overlap
ChIP U2OS ENCSR000EYD.SETDB1.U2OS 94 bp overlap
SMAD1 1 dataset
ChIP CD34_PROG_BMP GSE29194.SMAD1.CD34_PROG_BMP 151 bp overlap
SMAD2-3 2 datasets
ChIP HGrC1_EV-TGF GSE138496.SMAD2-3.HGrC1_EV-TGF 144 bp overlap
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 424 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 260 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 376 bp overlap
SMAD3 1 dataset
ChIP NCI-H441 GSE51509.SMAD3.NCI-H441 60 bp overlap
SMAD4 1 dataset
ChIP Caco-2 GSE112946.SMAD4.Caco-2 209 bp overlap
SMARCA4 5 datasets
ChIP CTV-1_DSG_SPI1-mut GSE128835.SMARCA4.CTV-1_DSG_SPI1-mut 245 bp overlap
ChIP CTV-1_FLAG_SPI1-mut GSE128835.SMARCA4.CTV-1_FLAG_SPI1-mut 201 bp overlap
ChIP CTV-1_delA GSE128835.SMARCA4.CTV-1_delA 256 bp overlap
ChIP CTV-1_delQ GSE128835.SMARCA4.CTV-1_delQ 188 bp overlap
ChIP NGP_ARID1A-mut2 GSE134626.SMARCA4.NGP_ARID1A-mut2 142 bp overlap
SMARCE1 1 dataset
ChIP K-562 ENCSR157TCS.SMARCE1.K-562 256 bp overlap
SOX10 1 dataset
Motif DE_48h DE_48h-SOX10_MA0442.3 6 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 285 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 490 bp overlap
TAL1 7 datasets
ChIP K-562 GSE107726.TAL1.K-562 207 bp overlap
ChIP K-562_dCas9-KRAB GSE132212.TAL1.K-562_dCas9-KRAB 220 bp overlap
ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 188 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 142 bp overlap
ChIP K-562_sgGal4 GSE132212.TAL1.K-562_sgGal4 181 bp overlap
ChIP MOLT-3 GSE59657.TAL1.MOLT-3 199 bp overlap
ChIP ProEs GSE59087.TAL1.ProEs 167 bp overlap
TBX2 1 dataset
ChIP Kelly GSE94822.TBX2.Kelly 222 bp overlap
TCF3 1 dataset
ChIP Kasumi-1 GSE43834.TCF3.Kasumi-1 237 bp overlap
TEAD4 1 dataset
ChIP K562 ENCFF673NIK 125 bp overlap
TFAP4 1 dataset
ChIP DLD-1 GSE46935.TFAP4.DLD-1 251 bp overlap
TRPS1 4 datasets
Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
ZBTB7A 2 datasets
ChIP HUDEP-2 GSE103445.ZBTB7A.HUDEP-2 334 bp overlap
ChIP K-562 GSE103445.ZBTB7A.K-562 224 bp overlap
ZMIZ1 1 dataset
ChIP THP-6_shEts1 GSE138516.ZMIZ1.THP-6_shEts1 276 bp overlap
ZNF136 1 dataset
Motif DE_48h DE_48h-ZNF136_MA1588.1 15 bp overlap
ZNF143 1 dataset
Motif DE_48h DE_48h-ZNF143_MA0088.2 16 bp overlap
ZNF354A 1 dataset
Motif DE_48h DE_48h-ZNF354A_MA1978.2 20 bp overlap
ZNF449 1 dataset
Motif DE_48h DE_48h-ZNF449_MA1656.2 10 bp overlap
ZNF558 1 dataset
Motif DE_48h DE_48h-ZNF558_MA2335.1 29 bp overlap
ZNF675 4 datasets
Motif DE_36h DE_36h-ZNF675_MA1714.2 19 bp overlap
Motif DE_48h DE_48h-ZNF675_MA1714.2 19 bp overlap
Motif DE_48h DE_48h-ZNF675_MA1714.2 19 bp overlap
Motif DE_60h DE_60h-ZNF675_MA1714.2 19 bp overlap
ZNF823 1 dataset
ChIP HEK293T GSE78099.ZNF823.HEK293T 151 bp overlap
ZNF85 1 dataset
Motif DE_48h DE_48h-ZNF85_MA1720.2 12 bp overlap
ZXDB 2 datasets
ChIP HEK293 ENCFF835SGA 521 bp overlap
ChIP HEK293 ENCSR559IOZ.ZXDB.HEK293 369 bp overlap
Znf423 1 dataset
Motif DE_48h DE_48h-Znf423_MA0116.1 15 bp overlap
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