chr17:40,483,550–40,484,556

chr17 : 40,483,550 – 40,484,556

1,006 bp 84 TFs 7 linked genes

This 1.0 kb open chromatin element is linked to 7 target genes and is bound by 84 transcription factors.

Linked Genes

7 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000279806		8.3 kb	Proximal	Proximity
TNS4		17.7 kb	Distal	Multiome
IGFBP4		40.5 kb	Distal	Multiome
TOP2A		66.0 kb	Distal	Multiome
SMARCE1		163.9 kb	Distal	Multiome
CDC6		196.1 kb	Distal	Multiome
WIPF2		264.6 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

84 transcription factors

ChIP prostate_fetal-fibroblast GSE90772.AR.prostate_fetal-fibroblast 290 bp overlap

ARID1A 1 dataset

ChIP RMG-I GSE120058.ARID1A.RMG-I 272 bp overlap

ATOH8 1 dataset

ChIP A549 ENCFF772HNB 281 bp overlap

ChIP UM-RC-6 GSE101987.BAP1.UM-RC-6 489 bp overlap

BCL3 3 datasets

ChIP A-549 ENCSR000BQH.BCL3.A-549 230 bp overlap

ChIP A-549 ENCSR000BQH.BCL3.A-549 216 bp overlap

ChIP A549 ENCFF214WKT 247 bp overlap

BRCA1 1 dataset

ChIP MCF-10A GSE40591.BRCA1.MCF-10A 792 bp overlap

BRD4 26 datasets

ChIP CLL_patient3 GSE109411.BRD4.CLL_patient3 272 bp overlap

ChIP CLL_patient3 GSE109411.BRD4.CLL_patient3 114 bp overlap

ChIP COLO-205 GSE73319.BRD4.COLO-205 231 bp overlap

ChIP HCT-15 GSE73319.BRD4.HCT-15 211 bp overlap

ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 161 bp overlap

ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 178 bp overlap

ChIP MDA-MB-231_DMSO GSE116879.BRD4.MDA-MB-231_DMSO 287 bp overlap

ChIP MDA-MB-231_DMSO_rDNA GSE116879.BRD4.MDA-MB-231_DMSO_rDNA 287 bp overlap

ChIP MDA-MB-231_JQ1-neg_S_3f GSE136151.BRD4.MDA-MB-231_JQ1-neg_S_3f 345 bp overlap

ChIP SUM1315_DMSO GSE63581.BRD4.SUM1315_DMSO 267 bp overlap

ChIP SUM1315_DMSO GSE63581.BRD4.SUM1315_DMSO 237 bp overlap

ChIP SUM1315_DMSO GSE63581.BRD4.SUM1315_DMSO 127 bp overlap

ChIP SUM159PT_100nMtrametinib_24h GSE87418.BRD4.SUM159PT_100nMtrametinib_24h 343 bp overlap

ChIP SUM159PT_DMSO_48h GSE87418.BRD4.SUM159PT_DMSO_48h 366 bp overlap

ChIP SUM159PT_DMSO_48h GSE87418.BRD4.SUM159PT_DMSO_48h 143 bp overlap

ChIP SUM159PT_Dox_48h GSE87418.BRD4.SUM159PT_Dox_48h 480 bp overlap

ChIP SUM159PT_Dox_48h GSE87418.BRD4.SUM159PT_Dox_48h 353 bp overlap

ChIP SUM159PT_KO GSE131097.BRD4.SUM159PT_KO 435 bp overlap

ChIP SUM159PT_scramble GSE131097.BRD4.SUM159PT_scramble 415 bp overlap

ChIP SUM159PT_shMYC_DMSO_48h GSE87418.BRD4.SUM159PT_shMYC_DMSO_48h 205 bp overlap

ChIP SUM159PT_shMYC_DMSO_48h GSE87418.BRD4.SUM159PT_shMYC_DMSO_48h 484 bp overlap

ChIP SUM159PT_shMYC_dox_48h GSE87418.BRD4.SUM159PT_shMYC_dox_48h 560 bp overlap

ChIP SUM159PT_shMYC_dox_48h GSE87418.BRD4.SUM159PT_shMYC_dox_48h 52 bp overlap

ChIP SW480 GSE73319.BRD4.SW480 152 bp overlap

ChIP keratinocyte GSE140992.BRD4.keratinocyte 393 bp overlap

ChIP keratinocyte GSE140992.BRD4.keratinocyte 322 bp overlap

CBFA2T3 2 datasets

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 427 bp overlap

ChIP K562 ENCFF673OEZ 411 bp overlap

CDKN1B 1 dataset

ChIP MDA-MB-231 GSE112444.CDKN1B.MDA-MB-231 219 bp overlap

CDX2 3 datasets

ChIP Caco-2_DIFF GSE23436.CDX2.Caco-2_DIFF 123 bp overlap

ChIP LS180 GSE31939.CDX2.LS180 182 bp overlap

ChIP LS180_125 GSE31939.CDX2.LS180_125 230 bp overlap

CTBP1 1 dataset

ChIP K-562 ENCSR201NQZ.CTBP1.K-562 305 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF335XTP 118 bp overlap

ChIP A-375 GSE116190.EGR1.A-375 131 bp overlap

ChIP A-549 ENCSR171TDM.EHF.A-549 699 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 682 bp overlap

ESR1 7 datasets

ChIP Ishikawa_DMSO_D538G_clone3 GSE132426.ESR1.Ishikawa_DMSO_D538G_clone3 226 bp overlap

ChIP MCF-7_estradiol-DHT_45min GSE99626.ESR1.MCF-7_estradiol-DHT_45min 168 bp overlap

ChIP U2OS_100nM-E2 GSE151039.ESR1.U2OS_100nM-E2 334 bp overlap

ChIP U2OS_10nM-E2 GSE151039.ESR1.U2OS_10nM-E2 330 bp overlap

ChIP U2OS_10nM-E2-B GSE151039.ESR1.U2OS_10nM-E2-B 344 bp overlap

ChIP U2OS_E2 GSE26110.ESR1.U2OS_E2 330 bp overlap

ChIP VCaP_E2_ERA GSE43985.ESR1.VCaP_E2_ERA 170 bp overlap

ChIP cardiomyocyte_D2 GSE129986.ETS1.cardiomyocyte_D2 288 bp overlap

ChIP HCT-116_A7A GSE152144.FOS.HCT-116_A7A 258 bp overlap

ChIP HCT-116_A7A GSE152144.FOS.HCT-116_A7A 667 bp overlap

FOXA2 3 datasets

ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.FOXA2.BJ1-hTERT_FOXA2_GATA4_Coexp 284 bp overlap

ChIP DE DE-FOXA2-1 728 bp overlap

ChIP DE DE-FOXA2-2 701 bp overlap

FOXF2 1 dataset

ChIP A-549 ENCSR445FHB.FOXF2.A-549 190 bp overlap

GATA2 1 dataset

ChIP SH-SY5Y ENCSR000EYB.GATA2.SH-SY5Y 227 bp overlap

GATA4 7 datasets

ChIP BJ1-hTERT GSE92491.GATA4.BJ1-hTERT 290 bp overlap

ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.GATA4.BJ1-hTERT_FOXA2_GATA4_Coexp 411 bp overlap

ChIP DE DE-GATA4-1 842 bp overlap

ChIP DE DE-GATA4-2 822 bp overlap

ChIP foregut GSE117136.GATA4.foregut 486 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 569 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 423 bp overlap

GATA6 16 datasets

ChIP AGS GSE51705.GATA6.AGS 223 bp overlap

ChIP DE DE-GATA6-1 770 bp overlap

ChIP DE DE-GATA6-2 1006 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 808 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 833 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 738 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 779 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 885 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 808 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 98 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 843 bp overlap

ChIP foregut GSE117136.GATA6.foregut 517 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 340 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 608 bp overlap

ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 275 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 363 bp overlap

HAND2 2 datasets

ChIP CLB-Ga GSE90683.HAND2.CLB-Ga 293 bp overlap

ChIP Kelly GSE94822.HAND2.Kelly 82 bp overlap

HNF4A 1 dataset

ChIP Caco-2_DIFF GSE23436.HNF4A.Caco-2_DIFF 129 bp overlap

HNRNPLL 1 dataset

ChIP K-562 ENCSR112RNT.HNRNPLL.K-562 173 bp overlap

HOXA7 3 datasets

ChIP A-549 ENCSR402OYZ.HOXA7.A-549 660 bp overlap

ChIP A549 ENCFF746ZBJ 331 bp overlap

ChIP A549 ENCFF746ZBJ 331 bp overlap

HOXB5 1 dataset

ChIP A549 ENCFF891VDO 222 bp overlap

JUN 10 datasets

ChIP 786-O GSE86092.JUN.786-O 107 bp overlap

ChIP A549 ENCFF846DUV 685 bp overlap

ChIP A549 ENCFF846DUV 554 bp overlap

ChIP A549 ENCFF846DUV 301 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 430 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 551 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 224 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 523 bp overlap

ChIP Karpas-299 GSE151413.JUN.Karpas-299 243 bp overlap

ChIP Karpas-299 GSE151413.JUN.Karpas-299 214 bp overlap

ChIP Karpas-299 GSE151413.JUNB.Karpas-299 123 bp overlap

ChIP A-549 ENCSR000BRF.JUND.A-549 126 bp overlap

KDM1A 2 datasets

ChIP pancreatic-progenitor_GT GSE104840.KDM1A.pancreatic-progenitor_GT 289 bp overlap

ChIP pancreatic-progenitor_PP2-KDM1A-inh GSE104840.KDM1A.pancreatic-progenitor_PP2-KDM1A-inh 327 bp overlap

ChIP keratinocyte GSE140991.KLF3.keratinocyte 270 bp overlap

MAML1 2 datasets

ChIP SCC_4h GSE156486.MAML1.SCC_4h 305 bp overlap

ChIP SCC_4h GSE156486.MAML1.SCC_4h 214 bp overlap

ChIP hMSC-TERT4_adipocyte-4H GSE113253.MED1.hMSC-TERT4_adipocyte-4H 262 bp overlap

MYBL2 4 datasets

ChIP MCF-10A_DOX GSE115787.MYBL2.MCF-10A_DOX 167 bp overlap

ChIP MCF-10A_DOX GSE115787.MYBL2.MCF-10A_DOX 381 bp overlap

ChIP MCF-10A_ctrl GSE115787.MYBL2.MCF-10A_ctrl 159 bp overlap

ChIP MCF-10A_ctrl GSE115787.MYBL2.MCF-10A_ctrl 685 bp overlap

ChIP Kelly GSE94822.MYCN.Kelly 124 bp overlap

NCAPH2 4 datasets

ChIP RMG-I GSE120058.NCAPH2.RMG-I 747 bp overlap

ChIP RMG-I GSE120058.NCAPH2.RMG-I 148 bp overlap

ChIP RMG-I_ARID1A-KO GSE120058.NCAPH2.RMG-I_ARID1A-KO 526 bp overlap

ChIP RMG-I_ARID1A-KO GSE120058.NCAPH2.RMG-I_ARID1A-KO 148 bp overlap

NCOR1 1 dataset

ChIP LS180_125 GSE39277.NCOR1.LS180_125 230 bp overlap

NCOR2 1 dataset

ChIP LS180_125 GSE39277.NCOR2.LS180_125 138 bp overlap

NELFE 1 dataset

ChIP K-562_NHS GSE112379.NELFE.K-562_NHS 168 bp overlap

NR2E3 2 datasets

ChIP A549 ENCFF833WDR 204 bp overlap

ChIP A549 ENCFF833WDR 97 bp overlap

NR2F1 1 dataset

ChIP K-562 ENCSR970NKQ.NR2F1.K-562 443 bp overlap

NR2F2 1 dataset

ChIP K-562 ENCSR000BRS.NR2F2.K-562 127 bp overlap

NR3C1 8 datasets

ChIP A-549 ENCSR000BHF.NR3C1.A-549 129 bp overlap

ChIP MCF-10A_DEX_60min GSE102355.NR3C1.MCF-10A_DEX_60min 72 bp overlap

ChIP MCF-10A_EGF_DEX_20min GSE102355.NR3C1.MCF-10A_EGF_DEX_20min 75 bp overlap

ChIP MCF-10A_EGF_DEX_60min GSE102355.NR3C1.MCF-10A_EGF_DEX_60min 55 bp overlap

ChIP U2OS_SHHIC5 GSE65847.NR3C1.U2OS_SHHIC5 94 bp overlap

ChIP U2OS_SHNS GSE65847.NR3C1.U2OS_SHNS 52 bp overlap

ChIP U2OS_siBRMsiHic5 GSE109383.NR3C1.U2OS_siBRMsiHic5 140 bp overlap

ChIP U2OS_siHic5siNS GSE109383.NR3C1.U2OS_siHic5siNS 173 bp overlap

NR5A2 1 dataset

ChIP A-549 ENCSR190GIW.NR5A2.A-549 686 bp overlap

ChIP HCT-116_ab20662 GSE97527.PAF1.HCT-116_ab20662 876 bp overlap

PARP1 1 dataset

ChIP MCF-10A GSE93038.PARP1.MCF-10A 202 bp overlap

PHIP 5 datasets

ChIP HCT-116_MLL1-KO__ab833 GSE101646.PHIP.HCT-116_MLL1-KO__ab833 161 bp overlap

ChIP HCT-116_MLL1-KO__ab833 GSE101646.PHIP.HCT-116_MLL1-KO__ab833 265 bp overlap

ChIP HCT-116_MLL1-KO__ab833 GSE101646.PHIP.HCT-116_MLL1-KO__ab833 98 bp overlap

ChIP HCT-116_ab833 GSE101646.PHIP.HCT-116_ab833 578 bp overlap

ChIP HCT-116_ab833 GSE101646.PHIP.HCT-116_ab833 214 bp overlap

POLR2A 8 datasets

ChIP A549 ENCFF034EBG 178 bp overlap

ChIP HeLa-S3 ENCFF045HUU 492 bp overlap

ChIP HeLa-S3 ENCFF224LWS 315 bp overlap

ChIP HeLa-S3 ENCFF773DNG 541 bp overlap

ChIP HeLa-S3 ENCFF773DNG 496 bp overlap

ChIP breast epithelium ENCFF045XXN 465 bp overlap

ChIP vagina ENCFF384GAB 191 bp overlap

ChIP vagina ENCFF384GAB 377 bp overlap

PRDM1 3 datasets

ChIP A-549 ENCSR977FEF.PRDM1.A-549 225 bp overlap

ChIP A-549 ENCSR977FEF.PRDM1.A-549 184 bp overlap

ChIP A549 ENCFF012KDW 117 bp overlap

PRDM14 1 dataset

ChIP NCCIT GSE71675.PRDM14.NCCIT 95 bp overlap

RBM25 1 dataset

ChIP K-562 ENCSR791OZM.RBM25.K-562 180 bp overlap

ChIP SCC_0h GSE156486.RBPJ.SCC_0h 517 bp overlap

RCOR1 1 dataset

ChIP keratinocyte_diff GSE57702.RCOR1.keratinocyte_diff 216 bp overlap

ChIP HDF_NUTLIN GSE77225.RELA.HDF_NUTLIN 79 bp overlap

RPA2_phospho 2 datasets

ChIP HeLa_shASF GSE108172.RPA2_phospho.HeLa_shASF 1006 bp overlap

ChIP HeLa_shTOP1 GSE108172.RPA2_phospho.HeLa_shTOP1 783 bp overlap

ChIP HepG2 ENCFF763IEA 147 bp overlap

SIRT6 1 dataset

ChIP SK-MEL-239_L-C-B GSE102813.SIRT6.SK-MEL-239_L-C-B 206 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 797 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 1006 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 725 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 510 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 728 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 521 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 809 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 748 bp overlap

SMAD3 3 datasets

ChIP H69_5Veh GSE145250.SMAD3.H69_5Veh 378 bp overlap

ChIP H69_5Veh GSE145250.SMAD3.H69_5Veh 559 bp overlap

ChIP endoderm GSE29422.SMAD3.endoderm 156 bp overlap

SMAD4 1 dataset

ChIP Caco-2 GSE112946.SMAD4.Caco-2 203 bp overlap

SMARCA4 2 datasets

ChIP BIN-67_lentivirus-SMARCA4 GSE117734.SMARCA4.BIN-67_lentivirus-SMARCA4 116 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 159 bp overlap

SMARCB1 1 dataset

ChIP HeLa-S3 ENCSR000EDK.SMARCB1.HeLa-S3 97 bp overlap

SMARCC1 2 datasets

ChIP DE_D1 S10-DE-d1-BAF155-exp1 245 bp overlap

ChIP DE_D1 S15-DE-d1-BAF155-exp1 435 bp overlap

SMARCE1 1 dataset

ChIP HMLE-Twist-ER_125nM_4OHT GSE96933.SMARCE1.HMLE-Twist-ER_125nM_4OHT 185 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 337 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 728 bp overlap

ChIP BIN-67_lentivirus-SMARCA4 GSE117734.SS18.BIN-67_lentivirus-SMARCA4 211 bp overlap

SUPT5H 5 datasets

ChIP DLD-1_NELFCD-AID_treated GSE144786.SUPT5H.DLD-1_NELFCD-AID_treated 213 bp overlap

ChIP DLD-1_NELFE-AID GSE144786.SUPT5H.DLD-1_NELFE-AID 326 bp overlap

ChIP DLD-1_NELFE-AID GSE144786.SUPT5H.DLD-1_NELFE-AID 523 bp overlap

ChIP HCT-116_DMSO GSE138548.SUPT5H.HCT-116_DMSO 490 bp overlap

ChIP HCT-116_DMSO_pThr806 GSE138548.SUPT5H.HCT-116_DMSO_pThr806 198 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 357 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 194 bp overlap

ChIP A549 ENCFF229ULU 171 bp overlap

ChIP A549 ENCFF399JYQ 317 bp overlap

TRIM25 1 dataset

ChIP MDA-MB-231 GSE79588.TRIM25.MDA-MB-231 86 bp overlap

XRN2 2 datasets

ChIP DLD-1_NELFCD-AID GSE144786.XRN2.DLD-1_NELFCD-AID 205 bp overlap

ChIP DLD-1_NELFCD-AID GSE144786.XRN2.DLD-1_NELFCD-AID 214 bp overlap

ZNF182 1 dataset

ChIP HEK293T GSE78099.ZNF182.HEK293T 143 bp overlap

ZNF257 1 dataset

ChIP HEK293T GSE78099.ZNF257.HEK293T 132 bp overlap

ZNF3 6 datasets

ChIP Hep-G2 ENCSR182QWU.ZNF3.Hep-G2 242 bp overlap

ChIP HepG2 ENCFF299MFD 139 bp overlap

ChIP K-562 ENCSR195QFV.ZNF3.K-562 407 bp overlap

ChIP K562 ENCFF233AOY 381 bp overlap

ChIP K562 ENCFF410DHO 345 bp overlap

ChIP K562 ENCFF540WBG 361 bp overlap

ZNF35 1 dataset

ChIP HEK293 GSE76494.ZNF35.HEK293 164 bp overlap

ZNF70 1 dataset

ChIP SK-N-SH ENCFF833ACX 295 bp overlap

ZNF736 1 dataset

ChIP HEK293T GSE78099.ZNF736.HEK293T 179 bp overlap

ZNF770 1 dataset

ChIP HEK293 ENCSR242BGR.ZNF770.HEK293 62 bp overlap

ZSCAN20 1 dataset

ChIP A549 ENCFF611TGC 270 bp overlap