chr17:4,745,124–4,745,511

chr17 : 4,745,124 – 4,745,511

387 bp 67 TFs 13 linked genes

This 387 bp open chromatin element is linked to 13 target genes and is bound by 67 transcription factors.

Linked Genes

13 genes

Gene	Expression	Dist. to TSS	Distance	Link type
CXCL16		5.2 kb	Proximal	Proximity
MED11		14.0 kb	Distal	Multiome
ARRB2		34.8 kb	Distal	Multiome
PELP1		41.3 kb	Distal	Multiome
PSMB6		50.7 kb	Distal	Multiome
PLD2		61.7 kb	Distal	Multiome
MINK1		87.9 kb	Distal	Multiome
MYBBP1A		190.1 kb	Distal	Multiome
SLC25A11		194.6 kb	Distal	Multiome
RNF167		194.6 kb	Distal	Multiome
PFN1		203.1 kb	Distal	Multiome
SPAG7		222.3 kb	Distal	Multiome
KIF1C		252.5 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

67 transcription factors

ChIP Hep-G2 ENCSR555ZMV.AGO1.Hep-G2 254 bp overlap

ARNTL 1 dataset

ChIP NSC_hNP1 GSE134972.ARNTL.NSC_hNP1 229 bp overlap

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 387 bp overlap

BCOR 2 datasets

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 387 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 387 bp overlap

ChIP HUES-64 GSE104059.BRD1.HUES-64 258 bp overlap

ChIP HUVEC-C GSE60171.BRD3.HUVEC-C 87 bp overlap

BRD4 4 datasets

ChIP CLL_patient2 GSE109411.BRD4.CLL_patient2 387 bp overlap

ChIP MDA-MB-157 ERP003925.BRD4.MDA-MB-157 105 bp overlap

ChIP hESC GSE33281.BRD4.hESC 86 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 387 bp overlap

ChIP K-562 ENCSR000ATU.CBX2.K-562 123 bp overlap

ChIP HCT-116 GSE72622.CDK9.HCT-116 189 bp overlap

CTCF 67 datasets

ChIP A-549 ENCSR000AUF.CTCF.A-549 253 bp overlap

ChIP BC-3 GSE135740.CTCF.BC-3 206 bp overlap

ChIP BJ ENCSR000DQI.CTCF.BJ 183 bp overlap

ChIP CD14 ENCSR000ATN.CTCF.CD14 383 bp overlap

ChIP GM09236__B-lymphocytes GSE111170.CTCF.GM09236__B-lymphocytes 141 bp overlap

ChIP GM09237_B-lymphocytes GSE111170.CTCF.GM09237_B-lymphocytes 182 bp overlap

ChIP GM12871 ENCSR000DRL.CTCF.GM12871 123 bp overlap

ChIP GM23338 ENCFF531QOI 387 bp overlap

ChIP GM23338 ENCFF772DML 201 bp overlap

ChIP H1 ENCFF230QSV 165 bp overlap

ChIP H1 ENCFF764RHO 277 bp overlap

ChIP H9 ENCFF152GTF 172 bp overlap

ChIP H9 ENCFF152GTF 251 bp overlap

ChIP HFF-Myc ENCFF680WYR 359 bp overlap

ChIP HT-1080_CBL0137-6h GSE122462.CTCF.HT-1080_CBL0137-6h 274 bp overlap

ChIP HUES-64_DNMT-KO GSE97394.CTCF.HUES-64_DNMT-KO 226 bp overlap

ChIP Hep-G2 ENCSR000DUG.CTCF.Hep-G2 200 bp overlap

ChIP HepG2 ENCFF127KUP 231 bp overlap

ChIP HepG2 ENCFF757EKU 350 bp overlap

ChIP IMR-90 ENCSR000EFI.CTCF.IMR-90 131 bp overlap

ChIP Kelly_resistant GSE103030.CTCF.Kelly_resistant 137 bp overlap

ChIP Kelly_sensitive GSE103030.CTCF.Kelly_sensitive 111 bp overlap

ChIP MM1-S GSE43743.CTCF.MM1-S 256 bp overlap

ChIP SK-N-SH ENCSR000DXQ.CTCF.SK-N-SH 130 bp overlap

ChIP WA01 ENCSR000DLK.CTCF.WA01 114 bp overlap

ChIP WA01_NEUR GSE52457.CTCF.WA01_NEUR 250 bp overlap

ChIP astrocyte of the spinal cord ENCFF213GKL 261 bp overlap

ChIP astrocyte_cerebellum ENCSR000DSZ.CTCF.astrocyte_cerebellum 243 bp overlap

ChIP astrocyte_spinal_cord ENCSR000DSU.CTCF.astrocyte_spinal_cord 124 bp overlap

ChIP bonchial_epithelial ENCSR000DXI.CTCF.bonchial_epithelial 111 bp overlap

ChIP brain ENCFF163BBN 387 bp overlap

ChIP brain ENCFF163BBN 335 bp overlap

ChIP cardiac_muscle ENCSR000DTI.CTCF.cardiac_muscle 274 bp overlap

ChIP chondrocyte ENCFF134ORZ 387 bp overlap

ChIP choroid plexus epithelial cell ENCFF407YNR 275 bp overlap

ChIP choroid-plexus_epithelial ENCSR000DTL.CTCF.choroid-plexus_epithelial 166 bp overlap

ChIP endodermal cell ENCFF471YCZ 373 bp overlap

ChIP endothelial cell of umbilical vein ENCFF677IZD 261 bp overlap

ChIP endothelial_brain-microvascular ENCSR000DTA.CTCF.endothelial_brain-microvascular 148 bp overlap

ChIP endothelial_umbilical-vein ENCSR000DVP.CTCF.endothelial_umbilical-vein 183 bp overlap

ChIP fibroblast_PULMONARY_ARTERY ENCSR000DUX.CTCF.fibroblast_PULMONARY_ARTERY 162 bp overlap

ChIP fibroblast_SKIN_LEG ENCSR000DPG.CTCF.fibroblast_SKIN_LEG 113 bp overlap

ChIP hESC_D0 GSE116862.CTCF.hESC_D0 160 bp overlap

ChIP heart ENCSR232OFD.CTCF.heart 291 bp overlap

ChIP hepatocyte ENCSR252QYR.CTCF.hepatocyte 207 bp overlap

ChIP hiPSC GSE115407.CTCF.hiPSC 237 bp overlap

ChIP hiPSC_CVI GSE106870.CTCF.hiPSC_CVI 172 bp overlap

ChIP hiPSC_IB12 GSE106870.CTCF.hiPSC_IB12 208 bp overlap

ChIP hiPSC_IB7 GSE106870.CTCF.hiPSC_IB7 166 bp overlap

ChIP hiPSC_IIA11 GSE106870.CTCF.hiPSC_IIA11 156 bp overlap

ChIP hiPSC_IID12 GSE106870.CTCF.hiPSC_IID12 204 bp overlap

ChIP hiPSC_IV8 GSE106870.CTCF.hiPSC_IV8 180 bp overlap

ChIP hiPSC_parental-line GSE106870.CTCF.hiPSC_parental-line 158 bp overlap

ChIP keratinocyte ENCSR000DNC.CTCF.keratinocyte 106 bp overlap

ChIP leukemia GSE142161.CTCF.leukemia 177 bp overlap

ChIP leukemia_CEBPA-24h GSE142161.CTCF.leukemia_CEBPA-24h 272 bp overlap

ChIP leukemia_CEBPA-96h GSE142161.CTCF.leukemia_CEBPA-96h 283 bp overlap

ChIP neural progenitor cell ENCFF420RBO 386 bp overlap

ChIP neural_progenitor ENCSR125NBL.CTCF.neural_progenitor 258 bp overlap

ChIP neutrophil ENCSR785YRL.CTCF.neutrophil 243 bp overlap

ChIP primary-epidermal-keratinocyte_diff_d0 GSE84657.CTCF.primary-epidermal-keratinocyte_diff_d0 204 bp overlap

ChIP primary-glioblastoma_G523 GSE121601.CTCF.primary-glioblastoma_G523 171 bp overlap

ChIP primary-glioblastoma_G567 GSE121601.CTCF.primary-glioblastoma_G567 153 bp overlap

ChIP primary-glioblastoma_G583 GSE121601.CTCF.primary-glioblastoma_G583 245 bp overlap

ChIP retinal pigment epithelial cell ENCFF810AAG 257 bp overlap

ChIP spleen ENCSR343RJH.CTCF.spleen 220 bp overlap

ChIP tibial-nerve ENCSR875NEW.CTCF.tibial-nerve 185 bp overlap

Cebpa 2 datasets

ChIP BLaER1 ENCFF262VBH 190 bp overlap

ChIP BLaER1 ENCFF274GAT 124 bp overlap

ChIP A-375 GSE116190.EGR1.A-375 217 bp overlap

EP300 1 dataset

ChIP osteoblast ENCSR000AUD.EP300.osteoblast 387 bp overlap

ChIP Ishikawa_DMSO_D538G_clone3 GSE132426.ESR1.Ishikawa_DMSO_D538G_clone3 174 bp overlap

ChIP cardiomyocyte_D0 GSE129986.ETS1.cardiomyocyte_D0 165 bp overlap

EZH2 14 datasets

ChIP H1 ENCFF232NZA 387 bp overlap

ChIP SU-DHL-6 GSE134136.EZH2.SU-DHL-6 347 bp overlap

ChIP astrocyte ENCFF365JTP 387 bp overlap

ChIP astrocyte ENCFF365JTP 106 bp overlap

ChIP astrocyte ENCSR000ARR.EZH2.astrocyte 387 bp overlap

ChIP endothelial_umbilical-vein ENCSR000ATA.EZH2.endothelial_umbilical-vein 334 bp overlap

ChIP fibroblast of dermis ENCFF029VZK 107 bp overlap

ChIP fibroblast_DERMAL ENCSR000ASE.EZH2.fibroblast_DERMAL 387 bp overlap

ChIP fibroblast_LUNG ENCSR000ARO.EZH2.fibroblast_LUNG 346 bp overlap

ChIP hepatocyte ENCSR384LYW.EZH2.hepatocyte 387 bp overlap

ChIP myotube ENCSR000ASZ.EZH2.myotube 325 bp overlap

ChIP neural progenitor cell ENCFF472NFV 387 bp overlap

ChIP neural progenitor cell ENCFF472NFV 105 bp overlap

ChIP neural_progenitor ENCSR069DPL.EZH2.neural_progenitor 387 bp overlap

FOXP1 1 dataset

ChIP H9 GSE31006.FOXP1.H9 148 bp overlap

GATA3 1 dataset

ChIP breast_tumor_Male_16 GSE104399.GATA3.breast_tumor_Male_16 56 bp overlap

GLIS2 1 dataset

ChIP HEK293 ENCSR535DIA.GLIS2.HEK293 249 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 211 bp overlap

HDAC2 2 datasets

ChIP H1 ENCFF353UJQ 387 bp overlap

ChIP WA01 ENCSR000AVB.HDAC2.WA01 319 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 244 bp overlap

HNRNPLL 1 dataset

ChIP Hep-G2 ENCSR804HMZ.HNRNPLL.Hep-G2 141 bp overlap

Motif DE_12h DE_12h-Hic1_MA0739.2 8 bp overlap

JARID2 2 datasets

ChIP MRC-5_IPS25_CTR GSE48515.JARID2.MRC-5_IPS25_CTR 237 bp overlap

ChIP MRC-5_IPS25_MEG3 GSE48515.JARID2.MRC-5_IPS25_MEG3 297 bp overlap

KDM3A 1 dataset

ChIP Hep-G2 ENCSR387JKT.KDM3A.Hep-G2 190 bp overlap

KDM4A 3 datasets

ChIP H1 ENCFF078LED 137 bp overlap

ChIP WA01 ENCSR000AVC.KDM4A.WA01 387 bp overlap

ChIP hiPSC_IIA11 GSE106870.KDM4A.hiPSC_IIA11 284 bp overlap

ChIP HEK293 ENCSR859BMR.KLF1.HEK293 107 bp overlap

KMT2A 1 dataset

ChIP Hep-G2 ENCSR692GFR.KMT2A.Hep-G2 121 bp overlap

ChIP IMR-90 ENCSR000EFF.MAZ.IMR-90 91 bp overlap

MCRS1 1 dataset

ChIP Huh-7 GSE97411.MCRS1.Huh-7 298 bp overlap

NFKB1 1 dataset

ChIP HEK293T GSE129618.NFKB1.HEK293T 138 bp overlap

ChIP HEK293 GSE89017.OGG1.HEK293 264 bp overlap

PCBP1 2 datasets

ChIP Hep-G2 GSE120104.PCBP1.Hep-G2 269 bp overlap

ChIP Hep-G2 ENCSR872EVQ.PCBP1.Hep-G2 229 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 387 bp overlap

ChIP WA01 ENCSR000ATK.PHF8.WA01 74 bp overlap

POLR2A 2 datasets

ChIP GM23338 ENCFF450WCS 194 bp overlap

ChIP GM23338 ENCFF450WCS 109 bp overlap

POU5F1 1 dataset

ChIP BG03 GSE21614.POU5F1.BG03 344 bp overlap

PTBP1 2 datasets

ChIP Hep-G2 ENCSR156APP.PTBP1.Hep-G2 101 bp overlap

ChIP Hep-G2 GSE120104.PTBP1.Hep-G2 88 bp overlap

RAD21 7 datasets

ChIP H1 ENCFF698EWO 241 bp overlap

ChIP Hep-G2 ENCSR054FKH.RAD21.Hep-G2 99 bp overlap

ChIP HepG2 ENCFF360ZSW 217 bp overlap

ChIP HepG2 ENCFF906QIS 225 bp overlap

ChIP hiPSC_IB12 GSE106870.RAD21.hiPSC_IB12 163 bp overlap

ChIP hiPSC_IV8 GSE106870.RAD21.hiPSC_IV8 215 bp overlap

ChIP hiPSC_failed-genome-editing GSE106870.RAD21.hiPSC_failed-genome-editing 156 bp overlap

RBBP5 4 datasets

ChIP H1 ENCFF905HFL 350 bp overlap

ChIP WA01 ENCSR000AQC.RBBP5.WA01 81 bp overlap

ChIP WA01 ENCSR000AQC.RBBP5.WA01 136 bp overlap

ChIP WA01 ENCSR000AQC.RBBP5.WA01 82 bp overlap

RBM39 3 datasets

ChIP Hep-G2 ENCSR339JTP.RBM39.Hep-G2 283 bp overlap

ChIP Hep-G2 GSE120104.RBM39.Hep-G2 387 bp overlap

ChIP Hep-G2 ENCSR339JTP.RBM39.Hep-G2 50 bp overlap

ChIP hiPSC_IB12 GSE106870.REST.hiPSC_IB12 162 bp overlap

ChIP WA01 GSE104690.RYBP.WA01 387 bp overlap

SAP30 1 dataset

ChIP WA01 ENCSR000ATR.SAP30.WA01 387 bp overlap

SIN3A 2 datasets

ChIP WA01 ENCSR000EBO.SIN3A.WA01 348 bp overlap

ChIP hiPSC_IB12 GSE106870.SIN3A.hiPSC_IB12 387 bp overlap

SMC1A 2 datasets

ChIP Hep-G2 GSE76893.SMC1A.Hep-G2 135 bp overlap

ChIP monocyte_INFg GSE98367.SMC1A.monocyte_INFg 138 bp overlap

ChIP peripheral-blood-neutrophil_Ecoli-1 GSE126755.SMC3.peripheral-blood-neutrophil_Ecoli-1 363 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 229 bp overlap

ChIP HEK293 GSE76494.SP1.HEK293 101 bp overlap

ChIP WTC11 ENCFF688PEU 387 bp overlap

ChIP HEK293 ENCSR807LQP.SP2.HEK293 104 bp overlap

ChIP HEK293 GSE76494.SP2.HEK293 89 bp overlap

SRSF1 1 dataset

ChIP Hep-G2 GSE120104.SRSF1.Hep-G2 286 bp overlap

SUZ12 1 dataset

ChIP hiPSC_WT GSE124903.SUZ12.hiPSC_WT 193 bp overlap

ChIP WA01 ENCSR000ECB.TBP.WA01 142 bp overlap

ChIP hESC_2h GSE122298.TBP.hESC_2h 162 bp overlap

ChIP hiPSC_WTb_RNase-neg GSE128135.TBP.hiPSC_WTb_RNase-neg 181 bp overlap

ChIP NPC GSE154479.TCF3.NPC 256 bp overlap

TFAP2C 1 dataset

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 82 bp overlap

TP53 2 datasets

ChIP hESC_DAMAGED GSE39912.TP53.hESC_DAMAGED 243 bp overlap

ChIP hESC_DIFF GSE39912.TP53.hESC_DIFF 136 bp overlap

TP63 2 datasets

ChIP breast-organoid GSE113909.TP63.breast-organoid 210 bp overlap

ChIP keratinocyte_diff GSE33571.TP63.keratinocyte_diff 60 bp overlap

ChIP WTC11 ENCFF139JAW 329 bp overlap

ChIP Huh-7 GSE97411.YY1.Huh-7 387 bp overlap

ZBTB2 1 dataset

ChIP Hep-G2 GSE97661.ZBTB2.Hep-G2 134 bp overlap

ZBTB38 1 dataset

ChIP HepG2 ENCFF875UQX 387 bp overlap

ZBTB48 2 datasets

ChIP HEK293 ENCFF809BPK 101 bp overlap

ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 293 bp overlap

ZBTB7B 1 dataset

ChIP Hep-G2 ENCSR322ULL.ZBTB7B.Hep-G2 132 bp overlap

ZNF143 1 dataset

ChIP WA01 ENCSR000EBW.ZNF143.WA01 189 bp overlap

ZNF263 1 dataset

ChIP K-562 ENCSR000EWN.ZNF263.K-562 330 bp overlap

ZNF883 1 dataset

ChIP Hep-G2 ENCSR882YYL.ZNF883.Hep-G2 142 bp overlap