chr12:52,014,577–52,015,139

chr12 : 52,014,577 – 52,015,139

562 bp 72 TFs 6 linked genes

This 562 bp open chromatin element is linked to 6 target genes and is bound by 72 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
TAMALIN		7.6 kb	Proximal	Proximity
NR4A1		22.3 kb	Distal	Multiome
ATG101		55.1 kb	Distal	Multiome
ACVR1B		63.2 kb	Distal	Multiome
FIGNL2		166.2 kb	Distal	Multiome
KRT7		217.7 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

72 transcription factors

ChIP HepG2 ENCFF773YDL 330 bp overlap

ARID1B 1 dataset

ChIP MCF-7_shJUN GSE128445.ARID1B.MCF-7_shJUN 294 bp overlap

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 281 bp overlap

BCL11A 1 dataset

ChIP MCF-10A ERP003925.BCL11A.MCF-10A 194 bp overlap

BCOR 3 datasets

ChIP WA01 GSE104690.BCOR.WA01 488 bp overlap

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 562 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 562 bp overlap

BRD4 6 datasets

ChIP CLL_patient2_4h_CpG_BET GSE109411.BRD4.CLL_patient2_4h_CpG_BET 214 bp overlap

ChIP COLO-741 GSE73319.BRD4.COLO-741 185 bp overlap

ChIP MCF-10A ERP003925.BRD4.MCF-10A 492 bp overlap

ChIP hESC GSE33281.BRD4.hESC 61 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 266 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 227 bp overlap

ChIP ME-1 GSE46044.CBFB.ME-1 217 bp overlap

ChIP T-47D_ETOH_5 GSE62428.CHD8.T-47D_ETOH_5 160 bp overlap

CREB1 1 dataset

ChIP WA01 ENCSR000BSN.CREB1.WA01 235 bp overlap

CTBP2 1 dataset

ChIP WA01 ENCSR000EUO.CTBP2.WA01 264 bp overlap

CTCF 8 datasets

ChIP B cell ENCFF500PZO 144 bp overlap

ChIP B cell ENCFF500PZO 367 bp overlap

ChIP B cell ENCFF506FKC 84 bp overlap

ChIP GM23338 ENCFF531QOI 54 bp overlap

ChIP T-47D_NaCl-isotonic-triptolide GSE111923.CTCF.T-47D_NaCl-isotonic-triptolide 250 bp overlap

ChIP endodermal cell ENCFF471YCZ 68 bp overlap

ChIP endodermal cell ENCFF471YCZ 270 bp overlap

ChIP erythroid GSE67783.CTCF.erythroid 272 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF031ISE 141 bp overlap

E2F6 3 datasets

ChIP H1 ENCFF785DWK 227 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 267 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 109 bp overlap

EGR1 2 datasets

ChIP H1 ENCFF451BLH 216 bp overlap

ChIP WA01 ENCSR000BJA.EGR1.WA01 329 bp overlap

EP300 2 datasets

ChIP MCF-7 GSE128445.EP300.MCF-7 176 bp overlap

ChIP NB4 GSE126720.EP300.NB4 54 bp overlap

ChIP CD34_NR29 GSE23730.ERG.CD34_NR29 562 bp overlap

ChIP K-562 GSE23730.ERG.K-562 220 bp overlap

ChIP K-562_DOX GSE23730.ERG.K-562_DOX 183 bp overlap

ESR1 2 datasets

ChIP Ishikawa GSE99905.ESR1.Ishikawa 190 bp overlap

ChIP MCF-7 GSE48930.ESR1.MCF-7 220 bp overlap

ChIP cardiomyocyte_D0 GSE129986.ETS1.cardiomyocyte_D0 170 bp overlap

EZH2 8 datasets

ChIP DU145_SH4 GSE135623.EZH2.DU145_SH4 315 bp overlap

ChIP GM23338 ENCSR045YHA.EZH2.GM23338 258 bp overlap

ChIP H1 ENCFF232NZA 514 bp overlap

ChIP WA01 ENCSR000ASY.EZH2.WA01 205 bp overlap

ChIP WA01 ENCSR000ASY.EZH2.WA01 53 bp overlap

ChIP hepatocyte ENCSR384LYW.EZH2.hepatocyte 163 bp overlap

ChIP neural_progenitor ENCSR069DPL.EZH2.neural_progenitor 261 bp overlap

ChIP neural_progenitor ENCSR069DPL.EZH2.neural_progenitor 61 bp overlap

EZH2_phosphoT487 4 datasets

ChIP hepatocyte ENCSR341VYI.EZH2_phosphoT487.hepatocyte 198 bp overlap

ChIP neural_progenitor ENCSR656MXA.EZH2_phosphoT487.neural_progenitor 182 bp overlap

ChIP neuron_bipolar_doxy_4d ENCSR886KKK.EZH2_phosphoT487.neuron_bipolar_doxy_4d 302 bp overlap

ChIP neuron_bipolar_doxy_4d ENCSR886KKK.EZH2_phosphoT487.neuron_bipolar_doxy_4d 72 bp overlap

ChIP NB4 GSE23730.FLI1.NB4 111 bp overlap

FOXK1 2 datasets

ChIP WTC11 ENCFF875IGU 181 bp overlap

ChIP WTC11 ENCFF875IGU 391 bp overlap

GABPA 2 datasets

ChIP WA01 ENCSR000BIW.GABPA.WA01 263 bp overlap

ChIP WA01 ENCSR000BIW.GABPA.WA01 125 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 90 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 196 bp overlap

HMGB1 1 dataset

ChIP HUVEC-C GSE98245.HMGB1.HUVEC-C 284 bp overlap

ChIP K-562 ENCSR005NMT.ID3.K-562 148 bp overlap

JARID2 3 datasets

ChIP MRC-5_IPS25_CTR GSE48515.JARID2.MRC-5_IPS25_CTR 191 bp overlap

ChIP MRC-5_IPS25_MEG3 GSE48515.JARID2.MRC-5_IPS25_MEG3 322 bp overlap

ChIP MRC-5_IPS25_MEG3 GSE48515.JARID2.MRC-5_IPS25_MEG3 138 bp overlap

JMJD1C 1 dataset

ChIP NB4 GSE63484.JMJD1C.NB4 143 bp overlap

KDM1A 1 dataset

ChIP NCI-H526_DMSO GSE66297.KDM1A.NCI-H526_DMSO 179 bp overlap

KDM4A 5 datasets

ChIP H1 ENCFF078LED 562 bp overlap

ChIP WA01 ENCSR000AVC.KDM4A.WA01 562 bp overlap

ChIP hiPSC_IA12 GSE106870.KDM4A.hiPSC_IA12 395 bp overlap

ChIP hiPSC_IIA11 GSE106870.KDM4A.hiPSC_IIA11 411 bp overlap

ChIP hiPSC_IID12 GSE106870.KDM4A.hiPSC_IID12 445 bp overlap

KMT2A 1 dataset

ChIP blood_cord GSE83671.KMT2A.blood_cord 558 bp overlap

ChIP THP-1_macrophage_PMA GSE96800.MAF1.THP-1_macrophage_PMA 416 bp overlap

ChIP H1 ENCFF914VQY 232 bp overlap

ChIP WTC11 ENCFF223QFY 473 bp overlap

ChIP HeLa GSE41006.MBD2.HeLa 562 bp overlap

MED1 2 datasets

ChIP HUVEC-C_siCTL GSE124892.MED1.HUVEC-C_siCTL 154 bp overlap

ChIP HUVEC-C_siERG GSE124892.MED1.HUVEC-C_siERG 249 bp overlap

ChIP DU145_SH4 GSE135623.MTF2.DU145_SH4 562 bp overlap

ChIP MOLT-3 GSE59657.MYB.MOLT-3 158 bp overlap

NFKB1 1 dataset

ChIP HEK293T_2KR GSE129618.NFKB1.HEK293T_2KR 50 bp overlap

NR2F2 2 datasets

ChIP MCF-7_E2 GSE132432.NR2F2.MCF-7_E2 562 bp overlap

ChIP MCF-7_Veh GSE132432.NR2F2.MCF-7_Veh 562 bp overlap

ChIP WA01 ENCSR000ECC.NRF1.WA01 114 bp overlap

OGG1 2 datasets

ChIP HEK293 GSE89017.OGG1.HEK293 164 bp overlap

ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 197 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 562 bp overlap

ChIP WA01 ENCSR000ATK.PHF8.WA01 320 bp overlap

ChIP NB4 GSE126720.PML.NB4 76 bp overlap

POLR2A 9 datasets

ChIP GM23338 ENCFF450WCS 417 bp overlap

ChIP GM23338 ENCFF450WCS 402 bp overlap

ChIP esophagus muscularis mucosa ENCFF791ZXN 274 bp overlap

ChIP spleen ENCFF044PYR 234 bp overlap

ChIP spleen ENCFF446ZGT 323 bp overlap

ChIP spleen ENCFF706IUS 390 bp overlap

ChIP spleen ENCFF706IUS 151 bp overlap

ChIP upper lobe of left lung ENCFF095BJW 275 bp overlap

ChIP upper lobe of left lung ENCFF199JUI 239 bp overlap

POU5F1 5 datasets

ChIP BJ1-hTERT GSE92491.POU5F1.BJ1-hTERT 106 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 518 bp overlap

ChIP SKM-1 GSE93706.POU5F1.SKM-1 268 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 342 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 132 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 562 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 562 bp overlap

RBFOX2 2 datasets

ChIP HepG2 ENCFF554DMZ 233 bp overlap

ChIP HepG2 ENCFF939HTZ 233 bp overlap

RNF2 5 datasets

ChIP WA01 GSE104690.RNF2.WA01 254 bp overlap

ChIP WA01 ENCSR784VUY.RNF2.WA01 249 bp overlap

ChIP WA01 GSE104690.RNF2.WA01 99 bp overlap

ChIP WA09 GSE105028.RNF2.WA09 477 bp overlap

ChIP WA09_heat-shock GSE105028.RNF2.WA09_heat-shock 437 bp overlap

RORC 2 datasets

ChIP HCC70 GSE126380.RORC.HCC70 562 bp overlap

ChIP HCC70_XY018 GSE126380.RORC.HCC70_XY018 525 bp overlap

RUNX1 2 datasets

ChIP AML GSE111821.RUNX1.AML 211 bp overlap

ChIP NB4 GSE81992.RUNX1.NB4 187 bp overlap

ChIP TSU-1621MT GSE60477.RXR.TSU-1621MT 148 bp overlap

ChIP WA01 GSE104690.RYBP.WA01 562 bp overlap

SIN3A 4 datasets

ChIP WA01 ENCSR000EBO.SIN3A.WA01 128 bp overlap

ChIP hiPSC_IA12 GSE106870.SIN3A.hiPSC_IA12 437 bp overlap

ChIP hiPSC_IB12 GSE106870.SIN3A.hiPSC_IB12 516 bp overlap

ChIP hiPSC_IID12 GSE106870.SIN3A.hiPSC_IID12 344 bp overlap

SIRT6 1 dataset

ChIP SK-MEL-239_L-C-B GSE102813.SIRT6.SK-MEL-239_L-C-B 524 bp overlap

SMAD2-3 1 dataset

ChIP HUVEC-C_TGFB1 GSE134556.SMAD2-3.HUVEC-C_TGFB1 285 bp overlap

SREBP2 2 datasets

ChIP HCC70 GSE126380.SREBP2.HCC70 562 bp overlap

ChIP HCC70_XY018 GSE126380.SREBP2.HCC70_XY018 544 bp overlap

STAT1_pS727 1 dataset

ChIP SET-2 GSE100566.STAT1_pS727.SET-2 82 bp overlap

STAT3 1 dataset

ChIP WA01 ERP004237.STAT3.WA01 201 bp overlap

SUZ12 5 datasets

ChIP H1 ENCFF881NFR 104 bp overlap

ChIP H1 ENCFF881NFR 541 bp overlap

ChIP H1 ENCFF881NFR 562 bp overlap

ChIP hiPSC GSE124903.SUZ12.hiPSC 556 bp overlap

ChIP hiPSC_WT GSE124903.SUZ12.hiPSC_WT 562 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 142 bp overlap

ChIP MOLT-3 GSE59657.TAL1.MOLT-3 109 bp overlap

ChIP WA01 ENCSR000ECB.TBP.WA01 175 bp overlap

TFAP2C 2 datasets

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 227 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 230 bp overlap

TFIIIC 1 dataset

ChIP HEK293 GSE119418.TFIIIC.HEK293 257 bp overlap

TRIM25 1 dataset

ChIP BT-549 GSE79588.TRIM25.BT-549 254 bp overlap

TRIM28 1 dataset

ChIP HCT-116 GSE72622.TRIM28.HCT-116 136 bp overlap

ChIP SMMC-7721 GSE126982.WDR5.SMMC-7721 562 bp overlap

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 562 bp overlap

ZNF141 1 dataset

ChIP HEK293T GSE78099.ZNF141.HEK293T 116 bp overlap