chr12:4,720,395–4,720,946

chr12 : 4,720,395 – 4,720,946

551 bp 69 TFs 6 linked genes

This 551 bp open chromatin element is linked to 6 target genes and is bound by 69 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
GALNT8		at TSS	At TSS	Proximity
GAU1		293 bp	At TSS	Proximity
NDUFA9		71.6 kb	Distal	Multiome
DYRK4		115.8 kb	Distal	Multiome
RAD51AP1		181.9 kb	Distal	Multiome
C12orf4		182.3 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

69 transcription factors

ChIP LNCaP-abl GSE39459.AR.LNCaP-abl 117 bp overlap

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 507 bp overlap

ChIP WA01 ENCSR000BQU.ATF2.WA01 372 bp overlap

BACH1 1 dataset

ChIP WA01 ENCSR000EBQ.BACH1.WA01 187 bp overlap

BCOR 4 datasets

ChIP WA01 GSE104690.BCOR.WA01 217 bp overlap

ChIP WA01_KDM2B_KO GSE104690.BCOR.WA01_KDM2B_KO 268 bp overlap

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 248 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 205 bp overlap

BRD4 3 datasets

ChIP hESC GSE33281.BRD4.hESC 61 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 258 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 358 bp overlap

CDX2 5 datasets

ChIP LS180 GSE31939.CDX2.LS180 111 bp overlap

ChIP LS180 GSE31939.CDX2.LS180 79 bp overlap

ChIP LS180_125 GSE31939.CDX2.LS180_125 195 bp overlap

ChIP LS180_125 GSE31939.CDX2.LS180_125 112 bp overlap

ChIP adult-duodenal-cell GSE115314.CDX2.adult-duodenal-cell 342 bp overlap

ChIP H1 ENCFF991MKH 302 bp overlap

CREB1 2 datasets

ChIP GM23338 ENCFF432ZEW 265 bp overlap

ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 374 bp overlap

CTBP2 1 dataset

ChIP WA01 ENCSR000EUO.CTBP2.WA01 337 bp overlap

ChIP hESC_NAIVE GSE69646.CTCF.hESC_NAIVE 244 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 262 bp overlap

EP300 1 dataset

ChIP hESC GSE17917.EP300.hESC 151 bp overlap

ChIP Ishikawa ENCSR000BQR.ESR1.Ishikawa 109 bp overlap

EZH2 8 datasets

ChIP A-1847_CARM1-KO GSE95643.EZH2.A-1847_CARM1-KO 510 bp overlap

ChIP HCT-116 ENCSR046HGP.EZH2.HCT-116 337 bp overlap

ChIP LNCaP-abl GSE39459.EZH2.LNCaP-abl 111 bp overlap

ChIP PC-9 ENCSR793USK.EZH2.PC-9 551 bp overlap

ChIP RL_CPI169-10d GSE134136.EZH2.RL_CPI169-10d 500 bp overlap

ChIP THP-1 GSE135024.EZH2.THP-1 277 bp overlap

ChIP hepatocyte ENCSR384LYW.EZH2.hepatocyte 155 bp overlap

ChIP keratinocyte ENCFF070STK 211 bp overlap

EZH2_phosphoT487 1 dataset

ChIP PC-9 ENCSR702GMW.EZH2_phosphoT487.PC-9 471 bp overlap

FLI1 2 datasets

ChIP A-673_1_KRAB_GFP GSE106914.FLI1.A-673_1_KRAB_GFP 210 bp overlap

ChIP A-673_2_KRAB_eSOX2_1 GSE106914.FLI1.A-673_2_KRAB_eSOX2_1 218 bp overlap

FOXA1 1 dataset

ChIP LS180 GSE140533.FOXA1.LS180 77 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 263 bp overlap

ChIP DE DE-FOXA2-2 281 bp overlap

FOXP1 1 dataset

ChIP H9 GSE31006.FOXP1.H9 167 bp overlap

FOXP4 1 dataset

ChIP WTC11 ENCFF708TAF 327 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 551 bp overlap

ChIP DE DE-GATA4-2 89 bp overlap

GATA6 11 datasets

ChIP DE DE-GATA6-1 185 bp overlap

ChIP DE DE-GATA6-1 229 bp overlap

ChIP DE DE-GATA6-2 259 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 407 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 551 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 551 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 546 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 548 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 369 bp overlap

ChIP foregut GSE117136.GATA6.foregut 331 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 319 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 531 bp overlap

HDAC2 2 datasets

ChIP WA01 ENCSR000BNR.HDAC2.WA01 236 bp overlap

ChIP WA01 ENCSR000AVB.HDAC2.WA01 155 bp overlap

HNF4A 1 dataset

ChIP GP5D GSE51234.HNF4A.GP5D 551 bp overlap

ChIP WA09_heat-shock GSE105028.HSF1.WA09_heat-shock 362 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 551 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 304 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 183 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 551 bp overlap

ChIP ESC S34-ESC-d0-JUN-exp2 324 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 353 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 551 bp overlap

JUND 2 datasets

ChIP GP5D GSE51234.JUND.GP5D 296 bp overlap

ChIP GP5D_SIRAD21 GSE51234.JUND.GP5D_SIRAD21 233 bp overlap

KLF4 2 datasets

ChIP BJ_INDUCED GSE36570.KLF4.BJ_INDUCED 110 bp overlap

ChIP hiPSC GSE56567.KLF4.hiPSC 183 bp overlap

KLF5 2 datasets

ChIP ESO-26 GSE132680.KLF5.ESO-26 226 bp overlap

ChIP GP5D GSE51234.KLF5.GP5D 392 bp overlap

ChIP hESC_PRIMED GSE69646.MED1.hESC_PRIMED 347 bp overlap

ChIP GP5D GSE51234.MYC.GP5D 307 bp overlap

NANOG 8 datasets

ChIP GM23338 ENCFF065NZG 239 bp overlap

ChIP GM23338 ENCSR061DGF.NANOG.GM23338 158 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 473 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 372 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 551 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 367 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 365 bp overlap

ChIP hESC GSE18292.NANOG.hESC 248 bp overlap

NCOR1 1 dataset

ChIP LS180_125 GSE39277.NCOR1.LS180_125 101 bp overlap

NELFCD 1 dataset

ChIP DLD-1_NELFCD-AID GSE144786.NELFCD.DLD-1_NELFCD-AID 264 bp overlap

NELFE 1 dataset

ChIP DLD-1_NELFCD-AID GSE144786.NELFE.DLD-1_NELFCD-AID 377 bp overlap

NEUROD1 1 dataset

ChIP D283-Med GSE92582.NEUROD1.D283-Med 103 bp overlap

NIPBL 3 datasets

ChIP GP5D GSE51234.NIPBL.GP5D 395 bp overlap

ChIP WA09_heat-shock GSE105028.NIPBL.WA09_heat-shock 337 bp overlap

ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 209 bp overlap

POLR2A 1 dataset

ChIP transverse colon ENCFF610RWV 107 bp overlap

POU5F1 13 datasets

ChIP BJ_INDUCED GSE36570.POU5F1.BJ_INDUCED 115 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 404 bp overlap

ChIP GM23338 ENCFF333SNB 278 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 392 bp overlap

ChIP NCCIT GSE36134.POU5F1.NCCIT 237 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 551 bp overlap

ChIP WA09 GSE105028.POU5F1.WA09 222 bp overlap

ChIP WA09_heat-shock GSE105028.POU5F1.WA09_heat-shock 253 bp overlap

ChIP hESC ENCSR264RJX.POU5F1.hESC 184 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 313 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 506 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 217 bp overlap

ChIP hiPSC_3s2 GSE81899.POU5F1.hiPSC_3s2 228 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 337 bp overlap

PPARG 2 datasets

ChIP HT29_ROSIG_2H GSE77039.PPARG.HT29_ROSIG_2H 186 bp overlap

ChIP HT29_ROSIG_48H GSE77039.PPARG.HT29_ROSIG_48H 177 bp overlap

RAD21 1 dataset

ChIP GP5D GSE51234.RAD21.GP5D 152 bp overlap

REST 2 datasets

ChIP colorectal-cancer_CRC121_intact GSE112555.REST.colorectal-cancer_CRC121_intact 205 bp overlap

ChIP colorectal-cancer_shCTRL_dissociated GSE112555.REST.colorectal-cancer_shCTRL_dissociated 480 bp overlap

ChIP WA09_heat-shock GSE105028.RNF2.WA09_heat-shock 295 bp overlap

ChIP LS180 GSE31939.RXR.LS180 111 bp overlap

ChIP LS180_125 GSE31939.RXR.LS180_125 127 bp overlap

SCRT2 1 dataset

ChIP HEK293 ENCFF711QQB 162 bp overlap

SIN3A 2 datasets

ChIP H1 ENCFF042ZSL 410 bp overlap

ChIP H1 ENCFF042ZSL 207 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 265 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 282 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 413 bp overlap

SMAD2_3 4 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 283 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 272 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 272 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 246 bp overlap

SMAD3 3 datasets

ChIP BG03_DIFF_0H GSE36578.SMAD3.BG03_DIFF_0H 194 bp overlap

ChIP BG03_DIFF_2H GSE36578.SMAD3.BG03_DIFF_2H 142 bp overlap

ChIP hESC GSE29422.SMAD3.hESC 323 bp overlap

SMAD4 1 dataset

ChIP hESC GSE29422.SMAD4.hESC 149 bp overlap

SMARCA4 2 datasets

ChIP hiPSC GSE124903.SMARCA4.hiPSC 344 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 343 bp overlap

SMARCB1 2 datasets

ChIP hiPSC GSE124903.SMARCB1.hiPSC 461 bp overlap

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 471 bp overlap

SMARCC1 2 datasets

ChIP hiPSC GSE124903.SMARCC1.hiPSC 479 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 484 bp overlap

SOX2 2 datasets

ChIP hESC GSE18292.SOX2.hESC 128 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 296 bp overlap

ChIP H1 ENCFF263FUH 282 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 234 bp overlap

SUPT5H 2 datasets

ChIP DLD-1_NELFCD-AID GSE144786.SUPT5H.DLD-1_NELFCD-AID 266 bp overlap

ChIP DLD-1_NELFCD-AID_treated GSE144786.SUPT5H.DLD-1_NELFCD-AID_treated 257 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 221 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 240 bp overlap

ChIP WA01 ENCSR000ECB.TBP.WA01 171 bp overlap

TCF12 1 dataset

ChIP WA01 ENCSR000BIT.TCF12.WA01 171 bp overlap

ChIP NPC GSE154479.TCF3.NPC 249 bp overlap

TFAP2C 2 datasets

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 551 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 202 bp overlap

ChIP hESC_DIFF GSE39912.TP53.hESC_DIFF 344 bp overlap

ChIP NT2/D1 ENCFF999MII 325 bp overlap

ChIP NT2/D1 ENCFF999MII 150 bp overlap

ZNF207 1 dataset

ChIP WA09 GSE118632.ZNF207.WA09 242 bp overlap

ZNF423 1 dataset

ChIP WTC11 ENCFF574PBR 91 bp overlap

ZNF462 2 datasets

ChIP GM23338 ENCFF896CCA 251 bp overlap

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 506 bp overlap