chr10 : 6,163,113 – 6,163,281
168 bp 80 TFs 1 linked gene
This 168 bp open chromatin element is linked to PFKFB3 and is bound by 80 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
PFKFB3 550 bp At TSS Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr10:6,158,113 – 6,168,281
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
80 transcription factors
Source
Cell type
ATF7 1 dataset
ChIP K-562 ENCSR972ZBV.ATF7.K-562 168 bp overlap
BRD2 1 dataset
ChIP THP-1_iBET GSE138084.BRD2.THP-1_iBET 52 bp overlap
BRD4 7 datasets
ChIP CLL_patient1 GSE109411.BRD4.CLL_patient1 168 bp overlap
ChIP HUVEC-C_TNF GSE53998.BRD4.HUVEC-C_TNF 168 bp overlap
ChIP HUVEC-C_TNF_JQ1 GSE53998.BRD4.HUVEC-C_TNF_JQ1 168 bp overlap
ChIP Jurkat GSE83777.BRD4.Jurkat 67 bp overlap
ChIP NCI-H1963 GSE145028.BRD4.NCI-H1963 52 bp overlap
ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 53 bp overlap
ChIP retina_AB1-FW23 GSE86981.BRD4.retina_AB1-FW23 58 bp overlap
CREB3 1 dataset
ChIP K-562 ENCSR093FKD.CREB3.K-562 91 bp overlap
CUX1 1 dataset
ChIP K562 ENCFF902MYN 168 bp overlap
DDX20 3 datasets
ChIP K-562 ENCSR446LAV.DDX20.K-562 168 bp overlap
ChIP K562 ENCFF205RDN 168 bp overlap
ChIP K562 ENCFF205RDN 106 bp overlap
E4F1 1 dataset
ChIP K-562 ENCSR731LHZ.E4F1.K-562 96 bp overlap
EBF1 1 dataset
ChIP MUTUL GSE75503.EBF1.MUTUL 163 bp overlap
ESR1 1 dataset
ChIP MCF-7_TNFa_45m GSE67295.ESR1.MCF-7_TNFa_45m 109 bp overlap
ETS1 2 datasets
ChIP cardiomyocyte_D5 GSE129986.ETS1.cardiomyocyte_D5 74 bp overlap
ChIP cardiomyocyte_D9 GSE129986.ETS1.cardiomyocyte_D9 168 bp overlap
FOXA2 1 dataset
ChIP DE DE-FOXA2-2 168 bp overlap
GATA4 4 datasets
ChIP DE DE-GATA4-1 168 bp overlap
ChIP foregut GSE117136.GATA4.foregut 168 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 168 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 60 bp overlap
GATA6 9 datasets
ChIP DE DE-GATA6-1 168 bp overlap
ChIP DE DE-GATA6-2 78 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 159 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 147 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 168 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 168 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 168 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 168 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 168 bp overlap
GLIS1 2 datasets
ChIP HEK293 ENCFF299RSE 115 bp overlap
ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 168 bp overlap
GLIS2 1 dataset
ChIP HEK293 ENCSR535DIA.GLIS2.HEK293 168 bp overlap
HDAC1 1 dataset
ChIP K-562 ENCSR387UWP.HDAC1.K-562 168 bp overlap
HDGF 1 dataset
ChIP K-562 ENCSR563YDA.HDGF.K-562 168 bp overlap
HES1 1 dataset
ChIP K-562 ENCSR091JXL.HES1.K-562 106 bp overlap
IKZF1 4 datasets
ChIP K-562 ENCSR395HWC.IKZF1.K-562 168 bp overlap
ChIP K562 ENCFF348IBL 168 bp overlap
ChIP K562 ENCFF771OHZ 142 bp overlap
ChIP pre-B-cell GSE107886.IKZF1.pre-B-cell 168 bp overlap
IKZF3 1 dataset
ChIP HEK293 ENCSR304AMN.IKZF3.HEK293 168 bp overlap
ILF3 1 dataset
ChIP K-562 GSE103215.ILF3.K-562 168 bp overlap
IRF1 1 dataset
ChIP PDAC GSE64557.IRF1.PDAC 164 bp overlap
KAT7 1 dataset
ChIP K562 ENCFF175ZTN 71 bp overlap
KDM5B 1 dataset
ChIP K-562 ENCSR000AQA.KDM5B.K-562 134 bp overlap
KLF13 1 dataset
ChIP K-562 ENCSR608HVP.KLF13.K-562 167 bp overlap
KLF4 1 dataset
ChIP PDAC GSE64557.KLF4.PDAC 168 bp overlap
KLF6 1 dataset
ChIP PDAC GSE64557.KLF6.PDAC 162 bp overlap
KMT2A 4 datasets
ChIP HEK293T_C-term_shCtrl_TASP1-KO GSE90762.KMT2A.HEK293T_C-term_shCtrl_TASP1-KO 168 bp overlap
ChIP HEK293T_N-term_C104 GSE90762.KMT2A.HEK293T_N-term_C104 168 bp overlap
ChIP HEK293T_N-term_shCtrl_TASP1-KO GSE90762.KMT2A.HEK293T_N-term_shCtrl_TASP1-KO 168 bp overlap
ChIP blood_cord GSE83671.KMT2A.blood_cord 155 bp overlap
L3MBTL2 1 dataset
ChIP K-562 ENCSR530XQI.L3MBTL2.K-562 168 bp overlap
MAX 2 datasets
ChIP K-562 ENCSR000EFV.MAX.K-562 153 bp overlap
ChIP MDA-MB-468 GSE81381.MAX.MDA-MB-468 168 bp overlap
MAZ 2 datasets
ChIP HEK293 GSE76494.MAZ.HEK293 166 bp overlap
ChIP K-562 ENCSR000EFX.MAZ.K-562 123 bp overlap
MED1 1 dataset
ChIP G296S_4 GSE85628.MED1.G296S_4 168 bp overlap
MNT 3 datasets
ChIP K-562 ENCSR390VGH.MNT.K-562 83 bp overlap
ChIP K-562 ENCSR512NLO.MNT.K-562 168 bp overlap
ChIP K562 ENCFF342DNS 66 bp overlap
NBN 1 dataset
ChIP K-562 ENCSR085QEV.NBN.K-562 165 bp overlap
NCAPH2 1 dataset
ChIP IMR-90_Triptolide-30min GSE118494.NCAPH2.IMR-90_Triptolide-30min 96 bp overlap
NR2C1 4 datasets
ChIP K-562 ENCSR742IDN.NR2C1.K-562 168 bp overlap
ChIP K-562 ENCSR178DEG.NR2C1.K-562 144 bp overlap
ChIP K562 ENCFF239KMA 168 bp overlap
ChIP K562 ENCFF568JLK 61 bp overlap
NR2C2 1 dataset
ChIP K-562 ENCSR750LYM.NR2C2.K-562 144 bp overlap
NR2F1 2 datasets
ChIP K-562 ENCSR970NKQ.NR2F1.K-562 168 bp overlap
ChIP K562 ENCFF221HJH 168 bp overlap
NR2F2 5 datasets
ChIP K-562 ENCSR000BRS.NR2F2.K-562 168 bp overlap
ChIP liver ENCFF427MRU 145 bp overlap
ChIP liver ENCFF565JGD 168 bp overlap
ChIP liver ENCSR168SMX.NR2F2.liver 168 bp overlap
ChIP liver ENCSR338MMB.NR2F2.liver 146 bp overlap
NR2F6 3 datasets
ChIP K-562 ENCSR707QWA.NR2F6.K-562 168 bp overlap
ChIP K562 ENCFF239RSE 160 bp overlap
ChIP K562 ENCFF674RQA 168 bp overlap
NR3C1 4 datasets
ChIP BEAS-2B_TNF_IA1 GSE125623.NR3C1.BEAS-2B_TNF_IA1 168 bp overlap
ChIP BEAS-2B_Veh_IA1 GSE125623.NR3C1.BEAS-2B_Veh_IA1 127 bp overlap
ChIP T47D-A1-2_Dex GSE112491.NR3C1.T47D-A1-2_Dex 88 bp overlap
ChIP breast_tumor_Male_9 GSE104399.NR3C1.breast_tumor_Male_9 69 bp overlap
PATZ1 1 dataset
ChIP HEK293 ENCSR966ULI.PATZ1.HEK293 168 bp overlap
PGR 2 datasets
ChIP T-47D_progesterone GSE132649.PGR.T-47D_progesterone 109 bp overlap
ChIP myometrium_NP1 GSE137550.PGR.myometrium_NP1 168 bp overlap
PHIP 1 dataset
ChIP HCT-116_MLL1-KO__ab833 GSE101646.PHIP.HCT-116_MLL1-KO__ab833 124 bp overlap
POLR2A 2 datasets
ChIP gastroesophageal sphincter ENCFF826EZZ 54 bp overlap
ChIP sigmoid colon ENCFF653CQA 78 bp overlap
PRDM10 3 datasets
ChIP HEK293 ENCFF145WQQ 168 bp overlap
ChIP K-562 ENCSR120MPG.PRDM10.K-562 168 bp overlap
ChIP K562 ENCFF740YLK 168 bp overlap
RBBP4 1 dataset
ChIP SCMC GSE155861.RBBP4.SCMC 68 bp overlap
RELA 14 datasets
ChIP HUVEC-C_TNF GSE53998.RELA.HUVEC-C_TNF 168 bp overlap
ChIP HUVEC-C_TNF-30min GSE121890.RELA.HUVEC-C_TNF-30min 168 bp overlap
ChIP HUVEC-C_TNF-60min GSE121890.RELA.HUVEC-C_TNF-60min 94 bp overlap
ChIP HUVEC-C_TNF_30M GSE34500.RELA.HUVEC-C_TNF_30M 168 bp overlap
ChIP HUVEC-C_TNF_JQ1 GSE53998.RELA.HUVEC-C_TNF_JQ1 138 bp overlap
ChIP aortic-endothelial-cell_IL1B_D13 GSE139377.RELA.aortic-endothelial-cell_IL1B_D13 168 bp overlap
ChIP aortic-endothelial-cell_IL1B_D2 GSE139377.RELA.aortic-endothelial-cell_IL1B_D2 140 bp overlap
ChIP aortic-endothelial-cell_IL1B_D21 GSE139377.RELA.aortic-endothelial-cell_IL1B_D21 168 bp overlap
ChIP aortic-endothelial-cell_IL1B_D25 GSE139377.RELA.aortic-endothelial-cell_IL1B_D25 137 bp overlap
ChIP aortic-endothelial-cell_IL1B_D40 GSE139377.RELA.aortic-endothelial-cell_IL1B_D40 168 bp overlap
ChIP aortic-endothelial-cell_IL1B_D47 GSE139377.RELA.aortic-endothelial-cell_IL1B_D47 124 bp overlap
ChIP aortic-endothelial-cell_IL1B_D53 GSE139377.RELA.aortic-endothelial-cell_IL1B_D53 129 bp overlap
ChIP aortic-endothelial-cell_IL1B_D7 GSE139377.RELA.aortic-endothelial-cell_IL1B_D7 151 bp overlap
ChIP aortic-endothelial-cell_IL1B_D8 GSE139377.RELA.aortic-endothelial-cell_IL1B_D8 168 bp overlap
SALL3 1 dataset
ChIP hiPSC GSE104863.SALL3.hiPSC 51 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 168 bp overlap
SMAD2_3 1 dataset
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 149 bp overlap
SMARCA4 2 datasets
ChIP BIN-67_lentivirus-SMARCA4-K785R GSE117734.SMARCA4.BIN-67_lentivirus-SMARCA4-K785R 124 bp overlap
ChIP K-562 ENCSR587OQL.SMARCA4.K-562 168 bp overlap
SMARCC1 2 datasets
ChIP BIN-67_lentivirus-SMARCA4-T910M GSE117734.SMARCC1.BIN-67_lentivirus-SMARCA4-T910M 168 bp overlap
ChIP DE_D1 S15-DE-d1-BAF155-exp1 168 bp overlap
SMC3 1 dataset
ChIP peripheral-blood-neutrophil_Ecoli-1 GSE126755.SMC3.peripheral-blood-neutrophil_Ecoli-1 77 bp overlap
SP1 1 dataset
ChIP K-562 ENCSR991ELG.SP1.K-562 139 bp overlap
SP5_Hydra 1 dataset
ChIP HEK293_dDBD GSE110277.SP5_Hydra.HEK293_dDBD 126 bp overlap
SP7 1 dataset
ChIP HEK293 ENCSR468IJT.SP7.HEK293 168 bp overlap
SPI1 6 datasets
ChIP CTV-1_delA GSE128835.SPI1.CTV-1_delA 116 bp overlap
ChIP CTV-1_delQ GSE128835.SPI1.CTV-1_delQ 137 bp overlap
ChIP DC_96h_donorM GSE128834.SPI1.DC_96h_donorM 129 bp overlap
ChIP K-562 GSE70482.SPI1.K-562 131 bp overlap
ChIP Kasumi-1_SIRUNX1ETO GSE60130.SPI1.Kasumi-1_SIRUNX1ETO 121 bp overlap
ChIP monocyte GSE31621.SPI1.monocyte 89 bp overlap
SS18 2 datasets
ChIP BIN-67_lentivirus-SMARCA4 GSE117734.SS18.BIN-67_lentivirus-SMARCA4 166 bp overlap
ChIP BIN-67_lentivirus-SMARCA4-T910M GSE117734.SS18.BIN-67_lentivirus-SMARCA4-T910M 168 bp overlap
TCF3 3 datasets
ChIP Kasumi-1 GSE43834.TCF3.Kasumi-1 162 bp overlap
ChIP RCH-ACV GSE85988.TCF3.RCH-ACV 70 bp overlap
ChIP Ramos GSE139810.TCF3.Ramos 135 bp overlap
TEAD1 2 datasets
ChIP MSTO GSE68170.TEAD1.MSTO 168 bp overlap
ChIP pancreas_12D ERP008682.TEAD1.pancreas_12D 81 bp overlap
TEAD4 3 datasets
ChIP MCF-7_BLRP_WT_Veh GSE125594.TEAD4.MCF-7_BLRP_WT_Veh 148 bp overlap
ChIP MCF-7_E2 GSE125594.TEAD4.MCF-7_E2 101 bp overlap
ChIP MCF-7_Veh GSE125594.TEAD4.MCF-7_Veh 74 bp overlap
TFAP2C 1 dataset
ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 81 bp overlap
TRPS1 1 dataset
ChIP MCF-7 GSE133072.TRPS1.MCF-7 168 bp overlap
ZBTB20 1 dataset
ChIP HEK293 ENCFF524ADK 168 bp overlap
ZBTB26 1 dataset
ChIP HEK293 ENCSR229DYF.ZBTB26.HEK293 136 bp overlap
ZBTB40 2 datasets
ChIP K-562 ENCSR237VLT.ZBTB40.K-562 168 bp overlap
ChIP K562 ENCFF521DSV 168 bp overlap
ZEB1 1 dataset
ChIP PDAC GSE64557.ZEB1.PDAC 56 bp overlap
ZEB2 5 datasets
ChIP HEK293 ENCFF847JIE 168 bp overlap
ChIP HEK293 ENCSR417VWF.ZEB2.HEK293 168 bp overlap
ChIP K-562 ENCSR322CFO.ZEB2.K-562 168 bp overlap
ChIP K-562 ENCSR004GKA.ZEB2.K-562 168 bp overlap
ChIP K562 ENCFF795CMH 168 bp overlap
ZFP64 1 dataset
ChIP HEK293 GSE76494.ZFP64.HEK293 168 bp overlap
ZNF24 1 dataset
ChIP K-562 ENCSR117WTM.ZNF24.K-562 134 bp overlap
ZNF281 1 dataset
ChIP K562 ENCFF594VNM 168 bp overlap
ZNF335 2 datasets
ChIP HEK293 ENCFF784SLD 168 bp overlap
ChIP HEK293 ENCSR328SUD.ZNF335.HEK293 168 bp overlap
ZNF35 1 dataset
ChIP HEK293 GSE76494.ZNF35.HEK293 116 bp overlap
ZNF366 2 datasets
ChIP HEK293 ENCFF799ATK 168 bp overlap
ChIP HEK293 ENCSR106EBH.ZNF366.HEK293 111 bp overlap
ZNF561 1 dataset
ChIP HEK293 ENCSR125ULS.ZNF561.HEK293 159 bp overlap
ZNF584 1 dataset
ChIP K562 ENCFF771INO 168 bp overlap
ZNF592 1 dataset
ChIP K-562 ENCSR249BHQ.ZNF592.K-562 168 bp overlap
ZNF629 1 dataset
ChIP HEK293 ENCSR351NON.ZNF629.HEK293 168 bp overlap
ZNF83 2 datasets
ChIP K562 ENCFF340RTV 153 bp overlap
ChIP K562 ENCFF340RTV 168 bp overlap
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