chr1 : 169,899,265 – 169,900,114
849 bp 105 TFs 1 linked gene
This 849 bp open chromatin element is linked to SCYL3 and is bound by 105 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
SCYL3 5.4 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr1:169,894,265 – 169,905,114
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
105 transcription factors
Source
Cell type
ATF3 1 dataset
ChIP HCT-116_CAMP GSE74355.ATF3.HCT-116_CAMP 145 bp overlap
BACH1 1 dataset
Motif DE_12h DE_12h-BACH1_MA1633.2 9 bp overlap
BACH2 1 dataset
Motif DE_12h DE_12h-BACH2_MA1101.3 11 bp overlap
BRD4 2 datasets
ChIP SW480 GSE110473.BRD4.SW480 418 bp overlap
ChIP SW480_16h_TNF-a GSE110473.BRD4.SW480_16h_TNF-a 458 bp overlap
CTCF 1 dataset
ChIP T-47D_NaCl-1h GSE111923.CTCF.T-47D_NaCl-1h 178 bp overlap
CUX2 1 dataset
Motif DE_12h DE_12h-CUX2_MA0755.2 9 bp overlap
Cebpa 3 datasets
ChIP BLaER1 ENCFF031ISE 193 bp overlap
ChIP BLaER1 ENCFF335XTP 247 bp overlap
ChIP BLaER1 ENCFF346MCV 400 bp overlap
EGR1 1 dataset
ChIP A2780_cisplatin GSE129700.EGR1.A2780_cisplatin 163 bp overlap
EOMES 1 dataset
Motif DE_12h DE_12h-EOMES_MA0800.2 9 bp overlap
ETV1 1 dataset
Motif DE_12h DE_12h-ETV1_MA0761.3 9 bp overlap
Elf5 1 dataset
Motif DE_12h DE_12h-Elf5_MA0136.4 8 bp overlap
FIGLA 1 dataset
Motif DE_12h DE_12h-FIGLA_MA0820.2 6 bp overlap
FOS 1 dataset
Motif DE_12h DE_12h-FOS_MA0476.2 8 bp overlap
FOS::JUN 1 dataset
Motif DE_12h DE_12h-FOSJUN_MA0099.4 9 bp overlap
FOS::JUNB 1 dataset
Motif DE_12h DE_12h-FOSJUNB_MA1134.2 9 bp overlap
FOS::JUND 1 dataset
Motif DE_12h DE_12h-FOSJUND_MA1141.2 9 bp overlap
FOSB::JUNB 1 dataset
Motif DE_12h DE_12h-FOSBJUNB_MA1135.2 9 bp overlap
FOSL1 3 datasets
Motif DE_12h DE_12h-FOSL1_MA0477.3 9 bp overlap
ChIP HCT-116 ENCSR000BTE.FOSL1.HCT-116 222 bp overlap
ChIP HCT116 ENCFF540ZXN 397 bp overlap
FOSL1::JUN 1 dataset
Motif DE_12h DE_12h-FOSL1JUN_MA1128.2 9 bp overlap
FOSL1::JUNB 1 dataset
Motif DE_12h DE_12h-FOSL1JUNB_MA1137.2 9 bp overlap
FOSL1::JUND 1 dataset
Motif DE_12h DE_12h-FOSL1JUND_MA1142.2 8 bp overlap
FOSL2 1 dataset
Motif DE_12h DE_12h-FOSL2_MA0478.2 10 bp overlap
FOSL2::JUN 1 dataset
Motif DE_12h DE_12h-FOSL2JUN_MA1130.2 9 bp overlap
FOSL2::JUNB 1 dataset
Motif DE_12h DE_12h-FOSL2JUNB_MA1138.2 9 bp overlap
FOSL2::JUND 1 dataset
Motif DE_12h DE_12h-FOSL2JUND_MA1144.2 9 bp overlap
GATA4 1 dataset
ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.GATA4.BJ1-hTERT_FOXA2_GATA4_Coexp 175 bp overlap
GATA6 5 datasets
ChIP DE_D1 S09-DE-d1-GATA6-exp1 483 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 849 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 286 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 849 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 849 bp overlap
GRHL2 1 dataset
Motif DE_12h DE_12h-GRHL2_MA1105.3 8 bp overlap
HAND2 1 dataset
Motif DE_12h DE_12h-HAND2_MA1638.2 6 bp overlap
HNF4A 2 datasets
ChIP HCT-116_TCF4 GSE62890.HNF4A.HCT-116_TCF4 312 bp overlap
ChIP HCT-116_TCF4_DOX GSE62890.HNF4A.HCT-116_TCF4_DOX 333 bp overlap
HSF1 1 dataset
Motif DE_12h DE_12h-HSF1_MA0486.2 13 bp overlap
HSF2 1 dataset
Motif DE_12h DE_12h-HSF2_MA0770.1 13 bp overlap
Hmx2 1 dataset
Motif DE_12h DE_12h-Hmx2_MA0897.2 15 bp overlap
Hnf1A 1 dataset
Motif DE_12h DE_12h-Hnf1A_MA1991.2 10 bp overlap
IKZF2 2 datasets
Motif DE_12h DE_12h-IKZF2_MA2326.1 6 bp overlap
Motif DE_12h DE_12h-IKZF2_MA2326.1 6 bp overlap
JDP2 1 dataset
Motif DE_12h DE_12h-JDP2_MA0655.1 9 bp overlap
JUN 5 datasets
ChIP DE_D1 S08-DE-d1-JUN-exp1 783 bp overlap
ChIP DE_D1 S13-DE-d1-JUN-exp1 288 bp overlap
ChIP DE_D1 S40-DE-d1-JUN-exp2 849 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 364 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 849 bp overlap
JUNB 1 dataset
Motif DE_12h DE_12h-JUNB_MA0490.3 9 bp overlap
JUND 4 datasets
Motif DE_12h DE_12h-JUND_MA0491.3 9 bp overlap
Motif DE_12h DE_12h-JUND_MA0492.2 11 bp overlap
ChIP HCT-116 ENCSR000BSA.JUND.HCT-116 172 bp overlap
ChIP HCT116 ENCFF748ZQX 397 bp overlap
Jun 1 dataset
Motif DE_12h DE_12h-Jun_MA0489.3 8 bp overlap
KMT2B-D 1 dataset
ChIP SW480 GSE115985.KMT2B-D.SW480 497 bp overlap
MAFG::NFE2L1 1 dataset
Motif DE_12h DE_12h-MAFGNFE2L1_MA0089.3 11 bp overlap
MCM3 2 datasets
ChIP K-562 ENCSR990AZC.MCM3.K-562 68 bp overlap
ChIP K562 ENCFF121QKD 75 bp overlap
MEIS1 2 datasets
Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap
Motif DE_12h DE_12h-MEIS1_MA1639.2 9 bp overlap
MEIS2 1 dataset
Motif DE_12h DE_12h-MEIS2_MA1640.2 9 bp overlap
MGA 1 dataset
Motif DE_12h DE_12h-MGA_MA0801.1 8 bp overlap
MGA::EVX1 1 dataset
Motif DE_12h DE_12h-MGAEVX1_MA1960.2 11 bp overlap
NANOG 2 datasets
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 628 bp overlap
ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 367 bp overlap
NCOA2 1 dataset
ChIP MCF-7 ERP000901.NCOA2.MCF-7 133 bp overlap
NFE2 1 dataset
Motif DE_12h DE_12h-NFE2_MA0841.2 10 bp overlap
NFIB 1 dataset
Motif DE_12h DE_12h-NFIB_MA1643.2 17 bp overlap
NFIC 1 dataset
Motif DE_12h DE_12h-NFIC_MA1527.2 15 bp overlap
NFIC::TLX1 1 dataset
Motif DE_12h DE_12h-NFICTLX1_MA0119.1 14 bp overlap
NFYB 1 dataset
Motif DE_12h DE_12h-NFYB_MA0502.3 9 bp overlap
NKX2-4 2 datasets
Motif DE_12h DE_12h-NKX2-4_MA2003.2 8 bp overlap
Motif DE_12h DE_12h-NKX2-4_MA2003.2 8 bp overlap
ONECUT1 1 dataset
Motif DE_12h DE_12h-ONECUT1_MA0679.3 9 bp overlap
ONECUT2 2 datasets
ChIP AGS_Overexpression GSE113045.ONECUT2.AGS_Overexpression 261 bp overlap
Motif DE_12h DE_12h-ONECUT2_MA0756.3 8 bp overlap
PBX2 1 dataset
Motif DE_12h DE_12h-PBX2_MA1113.3 9 bp overlap
PHIP 5 datasets
ChIP HCT-116_MLL1-KO__ab833 GSE101646.PHIP.HCT-116_MLL1-KO__ab833 271 bp overlap
ChIP HCT-116_MLL1-KO__ab833 GSE101646.PHIP.HCT-116_MLL1-KO__ab833 399 bp overlap
ChIP HCT-116_ab833 GSE101646.PHIP.HCT-116_ab833 320 bp overlap
ChIP HCT-116_ab834 GSE101646.PHIP.HCT-116_ab834 399 bp overlap
ChIP HCT-116_ab834 GSE101646.PHIP.HCT-116_ab834 211 bp overlap
PLAG1 1 dataset
Motif DE_12h DE_12h-PLAG1_MA0163.1 14 bp overlap
POU2F1::SOX2 1 dataset
Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap
Plagl1 1 dataset
Motif DE_12h DE_12h-Plagl1_MA1615.2 8 bp overlap
Pou5f1::Sox2 1 dataset
Motif DE_12h DE_12h-Pou5f1Sox2_MA0142.1 15 bp overlap
RARA::RXRA 1 dataset
Motif DE_12h DE_12h-RARARXRA_MA0159.1 17 bp overlap
RNF2 1 dataset
ChIP fibroblast GSE139053.RNF2.fibroblast 75 bp overlap
RORB 1 dataset
Motif DE_12h DE_12h-RORB_MA1150.2 10 bp overlap
RORC 1 dataset
Motif DE_12h DE_12h-RORC_MA1151.2 10 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 469 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 849 bp overlap
SMAD2_3 3 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 489 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 337 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 672 bp overlap
SMARCA4 3 datasets
ChIP 501-mel_SHCTR GSE61965.SMARCA4.501-mel_SHCTR 265 bp overlap
ChIP 501-mel_SHSOX10 GSE61965.SMARCA4.501-mel_SHSOX10 271 bp overlap
ChIP hiPSC GSE124903.SMARCA4.hiPSC 201 bp overlap
SMARCC1 1 dataset
ChIP DE_D1 S10-DE-d1-BAF155-exp1 483 bp overlap
SMARCE1 1 dataset
ChIP HMLE-Twist-ER_125nM_4OHT GSE96933.SMARCE1.HMLE-Twist-ER_125nM_4OHT 181 bp overlap
SOX10 1 dataset
ChIP 501-mel GSE61965.SOX10.501-mel 303 bp overlap
SOX11 1 dataset
ChIP GRANT-A519 GSE52146.SOX11.GRANT-A519 90 bp overlap
SP1 2 datasets
ChIP HCT-116 ENCSR000BSF.SP1.HCT-116 136 bp overlap
ChIP HCT116 ENCFF800LBN 437 bp overlap
SP5 1 dataset
Motif DE_12h DE_12h-SP5_MA1965.2 6 bp overlap
SPDEF 1 dataset
Motif DE_12h DE_12h-SPDEF_MA0686.2 10 bp overlap
Stat4 1 dataset
Motif DE_12h DE_12h-Stat4_MA0518.2 10 bp overlap
TAL1_SCL 1 dataset
ChIP Jurkat GSE25000.TAL1_SCL.Jurkat 166 bp overlap
TBR1 1 dataset
Motif DE_12h DE_12h-TBR1_MA0802.2 9 bp overlap
TBX1 1 dataset
Motif DE_12h DE_12h-TBX1_MA0805.1 8 bp overlap
TBX15 1 dataset
Motif DE_12h DE_12h-TBX15_MA0803.1 8 bp overlap
TBX18 1 dataset
Motif DE_12h DE_12h-TBX18_MA1565.2 9 bp overlap
TBX2 1 dataset
Motif DE_12h DE_12h-TBX2_MA0688.2 9 bp overlap
TBX20 1 dataset
Motif DE_12h DE_12h-TBX20_MA0689.1 11 bp overlap
TBX21 1 dataset
Motif DE_12h DE_12h-TBX21_MA0690.3 10 bp overlap
TBX3 1 dataset
Motif DE_12h DE_12h-TBX3_MA1566.3 9 bp overlap
TBX4 1 dataset
Motif DE_12h DE_12h-TBX4_MA0806.1 8 bp overlap
TCF7L1 2 datasets
Motif DE_12h DE_12h-TCF7L1_MA1421.1 12 bp overlap
Motif DE_12h DE_12h-TCF7L1_MA1421.1 12 bp overlap
TCF7L2 5 datasets
Motif DE_12h DE_12h-TCF7L2_MA0523.2 9 bp overlap
ChIP HCT-116 ENCSR000EUV.TCF7L2.HCT-116 230 bp overlap
ChIP HCT-116_sc2 GSE127960.TCF7L2.HCT-116_sc2 265 bp overlap
ChIP HCT116 ENCFF038POZ 371 bp overlap
ChIP LNCaP GSE51621.TCF7L2.LNCaP 249 bp overlap
TGIF1 1 dataset
Motif DE_12h DE_12h-TGIF1_MA0796.1 12 bp overlap
TP53 2 datasets
ChIP SW480_0h_TNFa GSE102796.TP53.SW480_0h_TNFa 255 bp overlap
ChIP SW480_shp53_16h_TNF-a GSE115985.TP53.SW480_shp53_16h_TNF-a 330 bp overlap
Tbx6 1 dataset
Motif DE_12h DE_12h-Tbx6_MA1567.3 9 bp overlap
ZEB1 1 dataset
Motif DE_12h DE_12h-ZEB1_MA0103.4 6 bp overlap
ZFP14 1 dataset
Motif DE_12h DE_12h-ZFP14_MA1972.1 15 bp overlap
ZNF19 1 dataset
ChIP HEK293T GSE78099.ZNF19.HEK293T 78 bp overlap
ZNF324 1 dataset
Motif DE_12h DE_12h-ZNF324_MA1977.2 14 bp overlap
ZNF382 1 dataset
Motif DE_12h DE_12h-ZNF382_MA1594.1 24 bp overlap
ZNF418 2 datasets
Motif DE_12h DE_12h-ZNF418_MA1980.1 15 bp overlap
Motif DE_12h DE_12h-ZNF418_MA1980.1 15 bp overlap
ZNF549 1 dataset
Motif DE_12h DE_12h-ZNF549_MA1728.2 8 bp overlap
ZNF582 1 dataset
ChIP HEK293T GSE78099.ZNF582.HEK293T 78 bp overlap
ZNF680 1 dataset
Motif DE_12h DE_12h-ZNF680_MA1729.2 11 bp overlap
ZNF823 1 dataset
ChIP HEK293T GSE78099.ZNF823.HEK293T 290 bp overlap
ZSCAN4 1 dataset
Motif DE_12h DE_12h-ZSCAN4_MA1155.1 15 bp overlap
Zfp335 1 dataset
Motif DE_12h DE_12h-Zfp335_MA2002.2 7 bp overlap
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