chr2 : 221,576,514 – 221,576,980
466 bp 103 TFs 2 linked genes
This 466 bp open chromatin element is linked to ENSG00000272944 and EPHA4 and is bound by 103 transcription factors.
Linked Genes
2 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ENSG00000272944 4.0 kb Proximal Proximity
EPHA4 4.2 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr2:221,571,514 – 221,581,980
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
103 transcription factors
Source
Cell type
CEBPD 1 dataset
Motif DE_12h DE_12h-CEBPD_MA0836.3 8 bp overlap
CREB1 1 dataset
Motif DE_12h DE_12h-CREB1_MA0018.5 8 bp overlap
CTCF 1 dataset
ChIP Loucy ENCSR464DKE.CTCF.Loucy 196 bp overlap
CTNNB1 2 datasets
ChIP hESC_YAP-_activinA_15h GSE99202.CTNNB1.hESC_YAP-_activinA_15h 446 bp overlap
ChIP hiPSC_D2 GSE132532.CTNNB1.hiPSC_D2 210 bp overlap
DMRTC2 1 dataset
Motif DE_12h DE_12h-DMRTC2_MA1479.2 11 bp overlap
E2F6 1 dataset
Motif DE_12h DE_12h-E2F6_MA0471.3 8 bp overlap
ELF2 1 dataset
Motif DE_12h DE_12h-ELF2_MA1483.3 10 bp overlap
ELK1 1 dataset
Motif DE_12h DE_12h-ELK1_MA0028.3 9 bp overlap
ELK3 1 dataset
Motif DE_12h DE_12h-ELK3_MA0759.3 9 bp overlap
ELK4 1 dataset
Motif DE_12h DE_12h-ELK4_MA0076.3 9 bp overlap
EOMES 1 dataset
Motif DE_12h DE_12h-EOMES_MA0800.2 9 bp overlap
ERF::NHLH1 1 dataset
Motif DE_12h DE_12h-ERFNHLH1_MA1938.2 16 bp overlap
ETS2 1 dataset
Motif DE_12h DE_12h-ETS2_MA1484.2 9 bp overlap
ETV2::HOXB13 1 dataset
Motif DE_12h DE_12h-ETV2HOXB13_MA1943.2 13 bp overlap
ETV4 1 dataset
Motif DE_12h DE_12h-ETV4_MA0764.4 9 bp overlap
ETV5 1 dataset
Motif DE_12h DE_12h-ETV5_MA0765.4 9 bp overlap
ETV5::FOXI1 1 dataset
Motif DE_12h DE_12h-ETV5FOXI1_MA1946.2 12 bp overlap
ETV5::FOXO1 1 dataset
Motif DE_12h DE_12h-ETV5FOXO1_MA1947.2 10 bp overlap
EZH2 1 dataset
ChIP LNCaP GSE39459.EZH2.LNCaP 230 bp overlap
FEV 1 dataset
Motif DE_12h DE_12h-FEV_MA0156.4 9 bp overlap
FIGLA 1 dataset
Motif DE_12h DE_12h-FIGLA_MA0820.2 6 bp overlap
FLI1 1 dataset
Motif DE_12h DE_12h-FLI1_MA0475.3 9 bp overlap
FOXB1 1 dataset
Motif DE_12h DE_12h-FOXB1_MA0845.1 11 bp overlap
FOXC1 1 dataset
Motif DE_12h DE_12h-FOXC1_MA0032.2 11 bp overlap
FOXC2 1 dataset
Motif DE_12h DE_12h-FOXC2_MA0846.2 11 bp overlap
FOXD2 2 datasets
Motif DE_12h DE_12h-FOXD2_MA0847.4 11 bp overlap
Motif DE_12h DE_12h-FOXD2_MA0847.4 11 bp overlap
FOXD3 1 dataset
Motif DE_12h DE_12h-FOXD3_MA0041.3 14 bp overlap
FOXE1 2 datasets
Motif DE_12h DE_12h-FOXE1_MA1487.3 12 bp overlap
Motif DE_12h DE_12h-FOXE1_MA1487.3 12 bp overlap
FOXO1::ELK1 1 dataset
Motif DE_12h DE_12h-FOXO1ELK1_MA1954.2 13 bp overlap
FOXO1::FLI1 1 dataset
Motif DE_12h DE_12h-FOXO1FLI1_MA1956.2 13 bp overlap
GATA6 5 datasets
ChIP DE_D1 S09-DE-d1-GATA6-exp1 466 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 358 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 391 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 430 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 419 bp overlap
HDAC2 1 dataset
ChIP WA01 ENCSR000AVB.HDAC2.WA01 139 bp overlap
HLF 1 dataset
Motif DE_12h DE_12h-HLF_MA0043.4 9 bp overlap
Hmga1 1 dataset
Motif DE_12h DE_12h-Hmga1_MA2124.1 8 bp overlap
Hnf1A 2 datasets
Motif DE_12h DE_12h-Hnf1A_MA1991.2 10 bp overlap
Motif DE_12h DE_12h-Hnf1A_MA1991.2 10 bp overlap
INSM1 1 dataset
Motif DE_12h DE_12h-INSM1_MA0155.1 12 bp overlap
ISL2 1 dataset
Motif DE_12h DE_12h-ISL2_MA0914.2 6 bp overlap
JUN 3 datasets
ChIP DE_D1 S08-DE-d1-JUN-exp1 466 bp overlap
ChIP DE_D1 S40-DE-d1-JUN-exp2 466 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 461 bp overlap
Lef1 2 datasets
Motif DE_12h DE_12h-Lef1_MA0768.3 8 bp overlap
Motif DE_12h DE_12h-Lef1_MA0768.3 8 bp overlap
MAF::NFE2 1 dataset
Motif DE_12h DE_12h-MAFNFE2_MA0501.2 11 bp overlap
MEIS1 2 datasets
Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap
Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap
MYF6 1 dataset
Motif DE_12h DE_12h-MYF6_MA0667.1 10 bp overlap
NANOG 5 datasets
ChIP WA01 ERP004238.NANOG.WA01 255 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 466 bp overlap
ChIP WA09 GSE105028.NANOG.WA09 303 bp overlap
ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 389 bp overlap
ChIP hESC GSE18292.NANOG.hESC 94 bp overlap
NFIL3 1 dataset
Motif DE_12h DE_12h-NFIL3_MA0025.3 9 bp overlap
NIPBL 2 datasets
ChIP hESC_WNT3A GSE64758.NIPBL.hESC_WNT3A 226 bp overlap
ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 290 bp overlap
NKX2-2 1 dataset
Motif DE_12h DE_12h-NKX2-2_MA1645.2 8 bp overlap
NR1I3 1 dataset
Motif DE_12h DE_12h-NR1I3_MA1534.2 8 bp overlap
Nfe2l2 1 dataset
Motif DE_12h DE_12h-Nfe2l2_MA0150.3 11 bp overlap
OSR1 1 dataset
Motif DE_12h DE_12h-OSR1_MA1542.2 8 bp overlap
PAX6 1 dataset
Motif DE_12h DE_12h-PAX6_MA0069.1 14 bp overlap
POU1F1 2 datasets
Motif DE_12h DE_12h-POU1F1_MA0784.3 14 bp overlap
Motif DE_12h DE_12h-POU1F1_MA0784.3 14 bp overlap
POU2F1 2 datasets
Motif DE_12h DE_12h-POU2F1_MA0785.2 9 bp overlap
Motif DE_12h DE_12h-POU2F1_MA0785.2 9 bp overlap
POU2F1::SOX2 2 datasets
Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap
Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap
POU2F2 2 datasets
Motif DE_12h DE_12h-POU2F2_MA0507.3 13 bp overlap
Motif DE_12h DE_12h-POU2F2_MA0507.3 13 bp overlap
POU2F3 3 datasets
Motif DE_12h DE_12h-POU2F3_MA0627.3 9 bp overlap
Motif DE_12h DE_12h-POU2F3_MA0627.3 9 bp overlap
ChIP NCI-H1048 GSE115123.POU2F3.NCI-H1048 189 bp overlap
POU3F1 2 datasets
Motif DE_12h DE_12h-POU3F1_MA0786.2 10 bp overlap
Motif DE_12h DE_12h-POU3F1_MA0786.2 10 bp overlap
POU3F2 2 datasets
Motif DE_12h DE_12h-POU3F2_MA0787.1 12 bp overlap
Motif DE_12h DE_12h-POU3F2_MA0787.1 12 bp overlap
POU3F3 2 datasets
Motif DE_12h DE_12h-POU3F3_MA0788.1 13 bp overlap
Motif DE_12h DE_12h-POU3F3_MA0788.1 13 bp overlap
POU3F4 1 dataset
Motif DE_12h DE_12h-POU3F4_MA0789.1 9 bp overlap
POU4F3 1 dataset
Motif DE_12h DE_12h-POU4F3_MA0791.2 12 bp overlap
POU5F1 3 datasets
Motif DE_12h DE_12h-POU5F1_MA1115.2 7 bp overlap
ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 437 bp overlap
ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 385 bp overlap
POU5F1B 2 datasets
Motif DE_12h DE_12h-POU5F1B_MA0792.1 9 bp overlap
Motif DE_12h DE_12h-POU5F1B_MA0792.1 9 bp overlap
Pou5f1::Sox2 1 dataset
Motif DE_12h DE_12h-Pou5f1Sox2_MA0142.1 15 bp overlap
RBPJ 2 datasets
Motif DE_12h DE_12h-RBPJ_MA1116.2 6 bp overlap
Motif DE_12h DE_12h-RBPJ_MA1116.2 6 bp overlap
SIX1 1 dataset
Motif DE_12h DE_12h-SIX1_MA1118.2 9 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 451 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 466 bp overlap
SMAD2_3 3 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 448 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 424 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 466 bp overlap
SMARCA4 2 datasets
ChIP HS-SY-2_HA-tagged GSE108926.SMARCA4.HS-SY-2_HA-tagged 452 bp overlap
ChIP hiPSC GSE124903.SMARCA4.hiPSC 257 bp overlap
SMARCC1 2 datasets
ChIP DE_D1 S10-DE-d1-BAF155-exp1 320 bp overlap
ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 258 bp overlap
SOX18 1 dataset
Motif DE_12h DE_12h-SOX18_MA1563.2 8 bp overlap
SOX2 3 datasets
ChIP H9 GSE46837.SOX2.H9 182 bp overlap
ChIP LK2_GFP GSE137459.SOX2.LK2_GFP 253 bp overlap
ChIP hiPSC GSE56567.SOX2.hiPSC 198 bp overlap
SOX21 1 dataset
Motif DE_12h DE_12h-SOX21_MA0866.1 15 bp overlap
SOX9 1 dataset
Motif DE_12h DE_12h-SOX9_MA0077.2 8 bp overlap
Sox17 1 dataset
Motif DE_12h DE_12h-Sox17_MA0078.3 10 bp overlap
Spi1 1 dataset
Motif DE_12h DE_12h-Spi1_MA0080.7 13 bp overlap
T 1 dataset
ChIP H9_MESODERM GSE60606.T.H9_MESODERM 334 bp overlap
TBR1 1 dataset
Motif DE_12h DE_12h-TBR1_MA0802.2 9 bp overlap
TBX18 1 dataset
Motif DE_12h DE_12h-TBX18_MA1565.2 9 bp overlap
TBX19 1 dataset
Motif DE_12h DE_12h-TBX19_MA0804.2 17 bp overlap
TBX2 1 dataset
Motif DE_12h DE_12h-TBX2_MA0688.2 9 bp overlap
TBX3 1 dataset
Motif DE_12h DE_12h-TBX3_MA1566.3 9 bp overlap
TBXT 1 dataset
Motif DE_12h DE_12h-TBXT_MA0009.2 16 bp overlap
TCF7 2 datasets
Motif DE_12h DE_12h-TCF7_MA0769.3 7 bp overlap
Motif DE_12h DE_12h-TCF7_MA0769.3 7 bp overlap
TCF7L1 1 dataset
Motif DE_12h DE_12h-TCF7L1_MA1421.1 12 bp overlap
TCF7L2 2 datasets
Motif DE_12h DE_12h-TCF7L2_MA0523.2 9 bp overlap
Motif DE_12h DE_12h-TCF7L2_MA0523.2 9 bp overlap
TP53 1 dataset
ChIP H9 GSE142050.TP53.H9 214 bp overlap
Tbx6 1 dataset
Motif DE_12h DE_12h-Tbx6_MA1567.3 9 bp overlap
Vdr 1 dataset
Motif DE_12h DE_12h-Vdr_MA0693.4 7 bp overlap
YY1 1 dataset
ChIP WA01 ENCSR000BKD.YY1.WA01 164 bp overlap
Yy1 1 dataset
Motif DE_12h DE_12h-Yy1_MA0095.4 8 bp overlap
ZBTB7A 1 dataset
Motif DE_12h DE_12h-ZBTB7A_MA0750.3 9 bp overlap
ZEB1 1 dataset
Motif DE_12h DE_12h-ZEB1_MA0103.4 6 bp overlap
ZFP42 1 dataset
Motif DE_12h DE_12h-ZFP42_MA1651.2 13 bp overlap
ZNF135 1 dataset
Motif DE_12h DE_12h-ZNF135_MA1587.1 14 bp overlap
ZNF214 1 dataset
Motif DE_12h DE_12h-ZNF214_MA1975.2 13 bp overlap
ZNF317 1 dataset
Motif DE_12h DE_12h-ZNF317_MA1593.2 8 bp overlap
ZNF331 1 dataset
Motif DE_12h DE_12h-ZNF331_MA1726.2 10 bp overlap
ZNF384 1 dataset
Motif DE_12h DE_12h-ZNF384_MA1125.2 8 bp overlap
ZNF582 1 dataset
Motif DE_12h DE_12h-ZNF582_MA1983.2 19 bp overlap
ZNF75A 2 datasets
Motif DE_12h DE_12h-ZNF75A_MA2097.1 12 bp overlap
Motif DE_12h DE_12h-ZNF75A_MA2097.1 12 bp overlap
ZNF75D 1 dataset
Motif DE_12h DE_12h-ZNF75D_MA1601.2 12 bp overlap
ZNF766 1 dataset
Motif DE_12h DE_12h-ZNF766_MA2098.1 9 bp overlap
ZSCAN31 1 dataset
Motif DE_12h DE_12h-ZSCAN31_MA1722.2 18 bp overlap
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