chr2:218,799,866–218,800,388

chr2 : 218,799,866 – 218,800,388

522 bp 82 TFs 9 linked genes

This 522 bp open chromatin element is linked to 9 target genes and is bound by 82 transcription factors.

Linked Genes

9 genes

Gene	Expression	Dist. to TSS	Distance	Link type
CYP27A1		18.6 kb	Distal	Multiome
TTLL4		89.5 kb	Distal	Multiome
ENSG00000288898		108.8 kb	Distal	Multiome
STK36		128.1 kb	Distal	Multiome
RNF25		128.4 kb	Distal	Multiome
ZNF142		140.8 kb	Distal	Multiome
BCS1L		141.6 kb	Distal	Multiome
CNOT9		231.4 kb	Distal	Multiome
USP37		232.0 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

82 transcription factors

ChIP LNCaP GSE80256.AR.LNCaP 238 bp overlap

ChIP LNCaP-abl GSE39459.AR.LNCaP-abl 92 bp overlap

ChIP LNCaP-abl_DMSO GSE80238.AR.LNCaP-abl_DMSO 114 bp overlap

ChIP prostate-cancer_PDX_35 GSE130408.AR.prostate-cancer_PDX_35 199 bp overlap

ChIP prostate_1636_T GSE130408.AR.prostate_1636_T 156 bp overlap

ChIP prostate_1798_T GSE130408.AR.prostate_1798_T 189 bp overlap

ChIP HEK293T GSE39579.BRD3.HEK293T 311 bp overlap

ChIP HEK293_Ctrl GSE129407.BRD4.HEK293_Ctrl 345 bp overlap

CREB1 1 dataset

ChIP LNCaP-abl_SHFOXA1 GSE63034.CREB1.LNCaP-abl_SHFOXA1 167 bp overlap

ChIP K-562_13004 GSE131349.CTCF.K-562_13004 100 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF031ISE 128 bp overlap

ChIP ProEs GSE59087.EED.ProEs 170 bp overlap

ChIP VCaP GSE49091.ERG.VCaP 190 bp overlap

ChIP breast_tumor_Male_14 GSE104399.ESR1.breast_tumor_Male_14 116 bp overlap

ChIP cardiomyocyte_D9 GSE129986.ETS1.cardiomyocyte_D9 208 bp overlap

EZH2 3 datasets

ChIP DND41 ENCSR000ASW.EZH2.DND41 355 bp overlap

ChIP Pfeiffer GSE45982.EZH2.Pfeiffer 156 bp overlap

ChIP SF8628 GSE94834.EZH2.SF8628 424 bp overlap

FEZF1 1 dataset

ChIP HEK293 GSE76494.FEZF1.HEK293 141 bp overlap

FOXA1 1 dataset

ChIP prostate-cancer_PDX_136 GSE130408.FOXA1.prostate-cancer_PDX_136 107 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 316 bp overlap

ChIP DE DE-FOXA2-2 242 bp overlap

FOXO1-PAX3 1 dataset

ChIP RH4_DMSO-6H GSE116344.FOXO1-PAX3.RH4_DMSO-6H 358 bp overlap

GATA1 1 dataset

ChIP HUDEP-2_30min GSE104676.GATA1.HUDEP-2_30min 55 bp overlap

GATA2 1 dataset

ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 243 bp overlap

GATA4 4 datasets

ChIP DE DE-GATA4-1 337 bp overlap

ChIP DE DE-GATA4-2 352 bp overlap

ChIP foregut GSE117136.GATA4.foregut 204 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 421 bp overlap

GATA6 12 datasets

ChIP AGS GSE51936.GATA6.AGS 79 bp overlap

ChIP DE DE-GATA6-1 456 bp overlap

ChIP DE DE-GATA6-2 436 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 298 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 191 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 259 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 206 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 410 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 232 bp overlap

ChIP foregut GSE117136.GATA6.foregut 211 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 452 bp overlap

ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 317 bp overlap

GRHL2 6 datasets

ChIP HBE GSE46194.GRHL2.HBE 139 bp overlap

ChIP LNCaP GSE80256.GRHL2.LNCaP 196 bp overlap

ChIP MCF-7 GSE109820.GRHL2.MCF-7 178 bp overlap

ChIP MCF-7-WS8_VEH GSE113092.GRHL2.MCF-7-WS8_VEH 136 bp overlap

ChIP MCF-7_E2_45min GSE109820.GRHL2.MCF-7_E2_45min 184 bp overlap

ChIP OVCA429 GSE71018.GRHL2.OVCA429 78 bp overlap

HDAC3 1 dataset

ChIP RH4_DMSO-6H GSE116344.HDAC3.RH4_DMSO-6H 385 bp overlap

HMGA1 1 dataset

ChIP IMR-90_ctrl GSE111841.HMGA1.IMR-90_ctrl 72 bp overlap

HOXB13 3 datasets

ChIP prostate-cancer_PDX_170-2 GSE130408.HOXB13.prostate-cancer_PDX_170-2 64 bp overlap

ChIP prostate_P13_T GSE130408.HOXB13.prostate_P13_T 169 bp overlap

ChIP prostate_P27 GSE130408.HOXB13.prostate_P27 105 bp overlap

Hnf1A 2 datasets

Motif DE_48h DE_48h-Hnf1A_MA1991.2 10 bp overlap

Motif DE_72h DE_72h-Hnf1A_MA1991.2 10 bp overlap

IKZF1 1 dataset

ChIP K-562 ENCSR395HWC.IKZF1.K-562 286 bp overlap

IKZF2 1 dataset

Motif DE_72h DE_72h-IKZF2_MA2326.1 6 bp overlap

ChIP GP5D_SIRAD21 GSE51234.JUND.GP5D_SIRAD21 288 bp overlap

KLF14 2 datasets

Motif DE_48h DE_48h-KLF14_MA0740.2 9 bp overlap

Motif DE_72h DE_72h-KLF14_MA0740.2 9 bp overlap

KLF16 2 datasets

Motif DE_48h DE_48h-KLF16_MA0741.1 11 bp overlap

Motif DE_72h DE_72h-KLF16_MA0741.1 11 bp overlap

KLF5 2 datasets

Motif DE_48h DE_48h-KLF5_MA0599.1 10 bp overlap

Motif DE_72h DE_72h-KLF5_MA0599.1 10 bp overlap

KLF9 2 datasets

Motif DE_48h DE_48h-KLF9_MA1107.3 11 bp overlap

Motif DE_72h DE_72h-KLF9_MA1107.3 11 bp overlap

Motif DE_48h DE_48h-MAZ_MA1522.2 8 bp overlap

Motif DE_72h DE_72h-MAZ_MA1522.2 8 bp overlap

ChIP HEK293 GSE76494.MAZ.HEK293 192 bp overlap

MECOM 2 datasets

ChIP SKH1 GSE102697.MECOM.SKH1 226 bp overlap

ChIP SKH1_CEBPA-ER GSE102697.MECOM.SKH1_CEBPA-ER 146 bp overlap

ChIP hESC_PRIMED GSE69646.MED1.hESC_PRIMED 306 bp overlap

NFYB 2 datasets

Motif DE_48h DE_48h-NFYB_MA0502.3 9 bp overlap

Motif DE_72h DE_72h-NFYB_MA0502.3 9 bp overlap

NKX2-5 1 dataset

ChIP hESC_ab3584 GSE89457.NKX2-5.hESC_ab3584 220 bp overlap

NOTCH3 1 dataset

ChIP TALL-1_GSI GSE104261.NOTCH3.TALL-1_GSI 238 bp overlap

NR3C1 1 dataset

ChIP A-549 ENCSR000BJR.NR3C1.A-549 104 bp overlap

Nanog 2 datasets

Motif DE_48h DE_48h-Nanog_MA2339.1 7 bp overlap

Motif DE_72h DE_72h-Nanog_MA2339.1 7 bp overlap

PATZ1 4 datasets

Motif DE_48h DE_48h-PATZ1_MA1961.2 11 bp overlap

Motif DE_72h DE_72h-PATZ1_MA1961.2 11 bp overlap

ChIP HEK293 ENCFF016MNJ 494 bp overlap

ChIP HEK293 ENCSR966ULI.PATZ1.HEK293 325 bp overlap

ChIP hiPSC GSE125768.PDX1.hiPSC 205 bp overlap

ChIP MCF-7_R5020 GSE68355.PGR.MCF-7_R5020 243 bp overlap

ChIP breast_tumor_Male_28 GSE104399.PGR.breast_tumor_Male_28 509 bp overlap

PKNOX1 2 datasets

ChIP HEK293T ENCFF174WDB 143 bp overlap

ChIP HEK293T ENCSR233FAG.PKNOX1.HEK293T 84 bp overlap

PLAG1 1 dataset

ChIP K-562 GSE111469.PLAG1.K-562 228 bp overlap

POLR2A 2 datasets

ChIP prostate gland ENCFF545MVF 302 bp overlap

ChIP prostate gland ENCFF881OMH 119 bp overlap

PRDM10 1 dataset

ChIP HEK293 ENCFF145WQQ 522 bp overlap

Pparg::Rxra 2 datasets

Motif DE_48h DE_48h-PpargRxra_MA0065.3 13 bp overlap

Motif DE_72h DE_72h-PpargRxra_MA0065.3 13 bp overlap

RBM22 3 datasets

ChIP HepG2 ENCFF292RVQ 444 bp overlap

ChIP HepG2 ENCFF292RVQ 237 bp overlap

ChIP HepG2 ENCFF561IAJ 447 bp overlap

SMAD2-3 2 datasets

ChIP HGrC1_WT GSE138496.SMAD2-3.HGrC1_WT 189 bp overlap

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 381 bp overlap

SMAD2_3 1 dataset

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 357 bp overlap

SMARCB1 1 dataset

ChIP MCF-7_4-hydroxytamoxifen GSE123284.SMARCB1.MCF-7_4-hydroxytamoxifen 119 bp overlap

SNAI2 1 dataset

ChIP SMS-CTR_D48 GSE137168.SNAI2.SMS-CTR_D48 320 bp overlap

SOX14 2 datasets

Motif DE_48h DE_48h-SOX14_MA1562.2 9 bp overlap

Motif DE_72h DE_72h-SOX14_MA1562.2 9 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 238 bp overlap

Motif DE_48h DE_48h-SP3_MA0746.3 11 bp overlap

Motif DE_72h DE_72h-SP3_MA0746.3 11 bp overlap

Motif DE_48h DE_48h-SP4_MA0685.2 9 bp overlap

Motif DE_72h DE_72h-SP4_MA0685.2 9 bp overlap

Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap

Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap

Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap

Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap

Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap

Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap

Motif DE_48h DE_48h-SP8_MA0747.2 11 bp overlap

Motif DE_72h DE_72h-SP8_MA0747.2 11 bp overlap

STAT3 3 datasets

ChIP HCC1187 GSE152203.STAT3.HCC1187 146 bp overlap

ChIP HCC70_EtOH GSE85579.STAT3.HCC70_EtOH 85 bp overlap

ChIP MCF-7_jc5838 GSE126004.STAT3.MCF-7_jc5838 237 bp overlap

Stat5a::Stat5b 2 datasets

Motif DE_48h DE_48h-Stat5aStat5b_MA0519.2 9 bp overlap

Motif DE_72h DE_72h-Stat5aStat5b_MA0519.2 9 bp overlap

ChIP PRIMA2 GSE33850.TAL1.PRIMA2 125 bp overlap

TBX5 3 datasets

ChIP G296S_4 GSE85628.TBX5.G296S_4 416 bp overlap

ChIP cardiomyocyte_5 GSE85628.TBX5.cardiomyocyte_5 358 bp overlap

ChIP hiPSC GSE81585.TBX5.hiPSC 272 bp overlap

Motif DE_48h DE_48h-Wt1_MA1627.2 10 bp overlap

Motif DE_72h DE_72h-Wt1_MA1627.2 10 bp overlap

ChIP Hep-G2_RBM25-KD GSE120104.YY1.Hep-G2_RBM25-KD 263 bp overlap

ZBTB12 1 dataset

Motif DE_72h DE_72h-ZBTB12_MA1649.2 7 bp overlap

ZBTB6 1 dataset

Motif DE_72h DE_72h-ZBTB6_MA1581.2 9 bp overlap

ZFP14 2 datasets

Motif DE_48h DE_48h-ZFP14_MA1972.1 15 bp overlap

Motif DE_72h DE_72h-ZFP14_MA1972.1 15 bp overlap

ZNF148 2 datasets

Motif DE_48h DE_48h-ZNF148_MA1653.2 10 bp overlap

Motif DE_72h DE_72h-ZNF148_MA1653.2 10 bp overlap

ZNF24 1 dataset

ChIP HEK293 ENCSR984MDV.ZNF24.HEK293 196 bp overlap

ZNF281 2 datasets

Motif DE_48h DE_48h-ZNF281_MA1630.3 10 bp overlap

Motif DE_72h DE_72h-ZNF281_MA1630.3 10 bp overlap

ZNF324 1 dataset

ChIP HEK293 GSE76494.ZNF324.HEK293 191 bp overlap

ZNF335 2 datasets

ChIP HEK293 ENCFF784SLD 120 bp overlap

ChIP HEK293 ENCSR328SUD.ZNF335.HEK293 522 bp overlap

ZNF528 1 dataset

ChIP HEK293 GSE76494.ZNF528.HEK293 347 bp overlap

ZNF550 1 dataset

ChIP Hep-G2 ENCSR198BHH.ZNF550.Hep-G2 277 bp overlap

ZNF554 1 dataset

ChIP HEK293 GSE76494.ZNF554.HEK293 138 bp overlap

ZNF660 1 dataset

ChIP HEK293 ENCSR283DOU.ZNF660.HEK293 262 bp overlap

ZNF684 2 datasets

Motif DE_48h DE_48h-ZNF684_MA1600.2 14 bp overlap

Motif DE_72h DE_72h-ZNF684_MA1600.2 14 bp overlap

ZNF701 2 datasets

Motif DE_48h DE_48h-ZNF701_MA1987.2 17 bp overlap

Motif DE_72h DE_72h-ZNF701_MA1987.2 17 bp overlap

ZNF740 2 datasets

Motif DE_48h DE_48h-ZNF740_MA0753.3 10 bp overlap

Motif DE_72h DE_72h-ZNF740_MA0753.3 10 bp overlap

ZNF770 2 datasets

ChIP HEK293 ENCSR242BGR.ZNF770.HEK293 266 bp overlap

ChIP HEK293 GSE76494.ZNF770.HEK293 273 bp overlap

ZSCAN18 1 dataset

ChIP WTC11 ENCFF867QWX 257 bp overlap

ZSCAN31 2 datasets

Motif DE_48h DE_48h-ZSCAN31_MA1722.2 18 bp overlap

Motif DE_72h DE_72h-ZSCAN31_MA1722.2 18 bp overlap