chr13 : 93,304,665 – 93,305,611
946 bp 134 TFs 1 linked gene
This 946 bp open chromatin element is linked to GPC6 and is bound by 134 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
GPC6 78.4 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr13:93,299,665 – 93,310,611
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
134 transcription factors
Source
Cell type
ASCL1 7 datasets
Motif DE_12h DE_12h-ASCL1_MA1631.2 9 bp overlap
Motif DE_36h DE_36h-ASCL1_MA1100.3 8 bp overlap
Motif DE_36h DE_36h-ASCL1_MA1631.2 9 bp overlap
ChIP NCI-H2107 GSE69394.ASCL1.NCI-H2107 184 bp overlap
ChIP NCI-H82 GSE69394.ASCL1.NCI-H82 296 bp overlap
ChIP NCI-H889 GSE69394.ASCL1.NCI-H889 119 bp overlap
ChIP SCLC_ASCLP GSE61197.ASCL1.SCLC_ASCLP 218 bp overlap
ASH2L 1 dataset
ChIP WA01 ENCSR850KIP.ASH2L.WA01 325 bp overlap
Ascl2 1 dataset
Motif DE_36h DE_36h-Ascl2_MA0816.1 10 bp overlap
BARHL1 3 datasets
Motif DE_12h DE_12h-BARHL1_MA0877.4 6 bp overlap
Motif DE_36h DE_36h-BARHL1_MA0877.4 6 bp overlap
Motif DE_60h DE_60h-BARHL1_MA0877.4 6 bp overlap
BARHL2 3 datasets
Motif DE_12h DE_12h-BARHL2_MA0635.2 6 bp overlap
Motif DE_36h DE_36h-BARHL2_MA0635.2 6 bp overlap
Motif DE_60h DE_60h-BARHL2_MA0635.2 6 bp overlap
BHLHE22 1 dataset
Motif DE_12h DE_12h-BHLHE22_MA1635.2 6 bp overlap
BRD4 2 datasets
ChIP NCI-H1963 GSE145028.BRD4.NCI-H1963 336 bp overlap
ChIP NCI-H1963_shNONT GSE145028.BRD4.NCI-H1963_shNONT 509 bp overlap
CBX8 1 dataset
ChIP K-562 ENCSR000ATW.CBX8.K-562 365 bp overlap
CHD2 1 dataset
ChIP SK-N-SH ENCSR274SLQ.CHD2.SK-N-SH 206 bp overlap
CREB1 1 dataset
Motif DE_12h DE_12h-CREB1_MA0018.5 8 bp overlap
ELF4 1 dataset
ChIP K562 ENCFF940SAL 311 bp overlap
EP300 2 datasets
ChIP SK-N-SH ENCFF829RWA 302 bp overlap
ChIP SK-N-SH ENCSR000EHV.EP300.SK-N-SH 213 bp overlap
ETV2::FOXI1 1 dataset
Motif DE_12h DE_12h-ETV2FOXI1_MA1942.2 11 bp overlap
ETV5::FIGLA 1 dataset
Motif DE_12h DE_12h-ETV5FIGLA_MA1945.2 14 bp overlap
EZH2 1 dataset
ChIP SU-DHL-5 GSE45982.EZH2.SU-DHL-5 64 bp overlap
FIGLA 7 datasets
Motif DE_12h DE_12h-FIGLA_MA0820.2 6 bp overlap
Motif DE_12h DE_12h-FIGLA_MA0820.2 6 bp overlap
Motif DE_36h DE_36h-FIGLA_MA0820.2 6 bp overlap
Motif DE_36h DE_36h-FIGLA_MA0820.2 6 bp overlap
Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap
Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap
Motif DE_72h DE_72h-FIGLA_MA0820.2 6 bp overlap
FOSL1::JUND 1 dataset
Motif DE_12h DE_12h-FOSL1JUND_MA1143.2 9 bp overlap
FOXA1 2 datasets
ChIP T-47D_shRNF2 GSE137579.FOXA1.T-47D_shRNF2 149 bp overlap
ChIP ZR751_E2 GSE72249.FOXA1.ZR751_E2 226 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 934 bp overlap
ChIP DE DE-FOXA2-2 888 bp overlap
FOXB1 1 dataset
Motif DE_12h DE_12h-FOXB1_MA0845.1 11 bp overlap
FOXD3 1 dataset
Motif DE_12h DE_12h-FOXD3_MA0041.3 14 bp overlap
FOXE1 3 datasets
Motif DE_36h DE_36h-FOXE1_MA1487.3 12 bp overlap
Motif DE_60h DE_60h-FOXE1_MA1487.3 12 bp overlap
Motif DE_60h DE_60h-FOXE1_MA1487.3 12 bp overlap
FOXJ2::ELF1 1 dataset
Motif DE_12h DE_12h-FOXJ2ELF1_MA1952.2 11 bp overlap
FOXO1::ELK3 1 dataset
Motif DE_12h DE_12h-FOXO1ELK3_MA1955.2 13 bp overlap
FOXO1::FLI1 1 dataset
Motif DE_12h DE_12h-FOXO1FLI1_MA1956.2 13 bp overlap
Foxl2 1 dataset
Motif DE_12h DE_12h-Foxl2_MA1607.2 10 bp overlap
GATA2 4 datasets
ChIP SH-SY5Y ENCFF485YIB 405 bp overlap
ChIP SH-SY5Y ENCSR000EYB.GATA2.SH-SY5Y 621 bp overlap
ChIP SK-N-SH ENCFF764OZD 384 bp overlap
ChIP SK-N-SH ENCSR706VOO.GATA2.SK-N-SH 273 bp overlap
GATA3 4 datasets
ChIP BE2C GSE65664.GATA3.BE2C 265 bp overlap
ChIP CLB-Ga GSE90683.GATA3.CLB-Ga 326 bp overlap
ChIP SH-SY5Y ENCSR000EXZ.GATA3.SH-SY5Y 442 bp overlap
ChIP T-47D ENCSR000BMX.GATA3.T-47D 139 bp overlap
GATA4 3 datasets
ChIP DE DE-GATA4-1 945 bp overlap
ChIP DE DE-GATA4-2 946 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 291 bp overlap
GATA6 8 datasets
ChIP DE DE-GATA6-1 867 bp overlap
ChIP DE DE-GATA6-2 946 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 518 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 737 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 720 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 798 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 721 bp overlap
GRHL2 1 dataset
Motif DE_36h DE_36h-GRHL2_MA1105.3 8 bp overlap
Gata3 1 dataset
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
HAND2 2 datasets
ChIP CLB-Ga GSE90683.HAND2.CLB-Ga 302 bp overlap
ChIP SK-N-BE2-C GSE94822.HAND2.SK-N-BE2-C 227 bp overlap
Hmga1 1 dataset
Motif DE_60h DE_60h-Hmga1_MA2124.1 8 bp overlap
Hoxd13 1 dataset
Motif DE_36h DE_36h-Hoxd13_MA0909.4 7 bp overlap
IRF4 1 dataset
Motif DE_12h DE_12h-IRF4_MA1419.2 14 bp overlap
IRF8 1 dataset
Motif DE_12h DE_12h-IRF8_MA0652.2 13 bp overlap
ISL1 1 dataset
ChIP SK-N-BE2-C GSE94822.ISL1.SK-N-BE2-C 244 bp overlap
Irf1 2 datasets
Motif DE_12h DE_12h-Irf1_MA0050.4 11 bp overlap
Motif DE_12h DE_12h-Irf1_MA0050.4 11 bp overlap
KDM1A 2 datasets
ChIP NCI-H526_DMSO GSE66297.KDM1A.NCI-H526_DMSO 212 bp overlap
ChIP SH-SY5Y_B3 GSE58258.KDM1A.SH-SY5Y_B3 215 bp overlap
MAX 1 dataset
ChIP NCI-H128 GSE41105.MAX.NCI-H128 218 bp overlap
MGA::EVX1 2 datasets
Motif DE_36h DE_36h-MGAEVX1_MA1960.2 11 bp overlap
Motif DE_36h DE_36h-MGAEVX1_MA1960.2 11 bp overlap
MYOD1 1 dataset
Motif DE_36h DE_36h-MYOD1_MA0499.3 9 bp overlap
MYOG 1 dataset
Motif DE_12h DE_12h-MYOG_MA0500.3 8 bp overlap
NANOG 5 datasets
ChIP HUES-8 GSE109524.NANOG.HUES-8 538 bp overlap
ChIP WA01 ERP004238.NANOG.WA01 390 bp overlap
ChIP WA01 ENCSR000BMT.NANOG.WA01 170 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 345 bp overlap
ChIP WA09 GSE105028.NANOG.WA09 302 bp overlap
NEUROD1 4 datasets
ChIP D283-Med GSE92582.NEUROD1.D283-Med 251 bp overlap
ChIP D341-Med_shGFP GSE92582.NEUROD1.D341-Med_shGFP 393 bp overlap
ChIP D341-Med_shNEUROD1-1154 GSE92582.NEUROD1.D341-Med_shNEUROD1-1154 199 bp overlap
ChIP D341-Med_shNEUROD1-1579 GSE92582.NEUROD1.D341-Med_shNEUROD1-1579 264 bp overlap
NHLH1 1 dataset
Motif DE_36h DE_36h-NHLH1_MA0048.3 9 bp overlap
NHLH2 3 datasets
Motif DE_12h DE_12h-NHLH2_MA1529.2 16 bp overlap
Motif DE_36h DE_36h-NHLH2_MA1529.2 16 bp overlap
Motif DE_60h DE_60h-NHLH2_MA1529.2 16 bp overlap
NR2C1 1 dataset
Motif DE_60h DE_60h-NR2C1_MA1535.2 6 bp overlap
NR2C2 1 dataset
Motif DE_60h DE_60h-NR2C2_MA1536.2 6 bp overlap
Neurod2 1 dataset
Motif DE_12h DE_12h-Neurod2_MA1993.2 6 bp overlap
Nr1H2 1 dataset
Motif DE_60h DE_60h-Nr1H2_MA1996.2 6 bp overlap
Nr1H4 1 dataset
Motif DE_60h DE_60h-Nr1H4_MA1110.3 6 bp overlap
Nr1h3 1 dataset
Motif DE_60h DE_60h-Nr1h3_MA2337.1 6 bp overlap
Olig2 1 dataset
Motif DE_12h DE_12h-Olig2_MA1997.2 6 bp overlap
PAX6 1 dataset
Motif DE_12h DE_12h-PAX6_MA0069.1 14 bp overlap
PDX1 1 dataset
ChIP hiPSC GSE125768.PDX1.hiPSC 205 bp overlap
PHOX2B 1 dataset
ChIP CLB-Ga GSE90683.PHOX2B.CLB-Ga 263 bp overlap
PITX3 1 dataset
ChIP SH-SY5Y GSE93275.PITX3.SH-SY5Y 328 bp overlap
POU1F1 1 dataset
Motif DE_12h DE_12h-POU1F1_MA0784.3 14 bp overlap
POU2F1 1 dataset
Motif DE_12h DE_12h-POU2F1_MA0785.2 9 bp overlap
POU2F2 1 dataset
Motif DE_12h DE_12h-POU2F2_MA0507.3 13 bp overlap
POU2F3 2 datasets
Motif DE_12h DE_12h-POU2F3_MA0627.3 9 bp overlap
ChIP NCI-H1048 GSE115123.POU2F3.NCI-H1048 216 bp overlap
POU3F1 1 dataset
Motif DE_12h DE_12h-POU3F1_MA0786.2 10 bp overlap
POU3F2 1 dataset
Motif DE_12h DE_12h-POU3F2_MA0787.1 12 bp overlap
POU3F3 1 dataset
Motif DE_12h DE_12h-POU3F3_MA0788.1 13 bp overlap
POU3F4 1 dataset
Motif DE_12h DE_12h-POU3F4_MA0789.1 9 bp overlap
POU5F1 2 datasets
Motif DE_12h DE_12h-POU5F1_MA1115.2 7 bp overlap
ChIP HUES-8 GSE109524.POU5F1.HUES-8 380 bp overlap
POU5F1B 1 dataset
Motif DE_12h DE_12h-POU5F1B_MA0792.1 9 bp overlap
PROX1 3 datasets
Motif DE_36h DE_36h-PROX1_MA0794.1 12 bp overlap
Motif DE_60h DE_60h-PROX1_MA0794.1 12 bp overlap
Motif DE_72h DE_72h-PROX1_MA0794.1 12 bp overlap
Pgr 1 dataset
Motif DE_12h DE_12h-Pgr_MA2323.1 17 bp overlap
Plagl1 1 dataset
Motif DE_60h DE_60h-Plagl1_MA1615.2 8 bp overlap
Ptf1A 2 datasets
Motif DE_12h DE_12h-Ptf1A_MA1620.2 8 bp overlap
Motif DE_60h DE_60h-Ptf1A_MA1620.2 8 bp overlap
RAD21 1 dataset
ChIP hiPSC_IIIB12 GSE106870.RAD21.hiPSC_IIIB12 146 bp overlap
RCOR1 1 dataset
ChIP SK-N-SH ENCSR009TKN.RCOR1.SK-N-SH 280 bp overlap
RELA 1 dataset
ChIP MCF-7_E2_45m GSE67295.RELA.MCF-7_E2_45m 167 bp overlap
SAFB 1 dataset
ChIP K-562 GSE120104.SAFB.K-562 75 bp overlap
SCRT1 2 datasets
Motif DE_36h DE_36h-SCRT1_MA0743.3 10 bp overlap
Motif DE_60h DE_60h-SCRT1_MA0743.3 10 bp overlap
SCRT2 2 datasets
Motif DE_36h DE_36h-SCRT2_MA0744.3 10 bp overlap
Motif DE_60h DE_60h-SCRT2_MA0744.3 10 bp overlap
SIX2 1 dataset
Motif DE_12h DE_12h-SIX2_MA1119.2 11 bp overlap
SMAD2 1 dataset
ChIP endoderm GSE29422.SMAD2.endoderm 135 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 867 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 668 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 806 bp overlap
SMAD2_3 3 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 436 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 397 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 697 bp overlap
SMARCB1 1 dataset
ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 234 bp overlap
SMARCC1 1 dataset
ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 187 bp overlap
SNAI1 2 datasets
Motif DE_12h DE_12h-SNAI1_MA1558.2 7 bp overlap
Motif DE_36h DE_36h-SNAI1_MA1558.2 7 bp overlap
SNAI2 1 dataset
Motif DE_36h DE_36h-SNAI2_MA0745.3 8 bp overlap
SNAI3 1 dataset
Motif DE_36h DE_36h-SNAI3_MA1559.2 9 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 240 bp overlap
SP1 1 dataset
ChIP WA01 ENCSR000BIR.SP1.WA01 196 bp overlap
SPI1 1 dataset
ChIP K-562 GSE70482.SPI1.K-562 52 bp overlap
SPIC 1 dataset
Motif DE_12h DE_12h-SPIC_MA0687.2 13 bp overlap
SREBF1 5 datasets
Motif DE_12h DE_12h-SREBF1_MA0829.3 10 bp overlap
Motif DE_36h DE_36h-SREBF1_MA0829.3 10 bp overlap
Motif DE_60h DE_60h-SREBF1_MA0595.1 10 bp overlap
Motif DE_60h DE_60h-SREBF1_MA0829.3 10 bp overlap
Motif DE_72h DE_72h-SREBF1_MA0829.3 10 bp overlap
STAT1 1 dataset
Motif DE_36h DE_36h-STAT1_MA0137.4 9 bp overlap
STAT3 1 dataset
Motif DE_36h DE_36h-STAT3_MA0144.3 9 bp overlap
Six3 1 dataset
Motif DE_12h DE_12h-Six3_MA0631.2 11 bp overlap
Spi1 1 dataset
Motif DE_12h DE_12h-Spi1_MA0080.7 13 bp overlap
Spz1 1 dataset
Motif DE_12h DE_12h-Spz1_MA0111.1 11 bp overlap
Stat2 1 dataset
Motif DE_12h DE_12h-Stat2_MA1623.2 10 bp overlap
Stat4 1 dataset
Motif DE_36h DE_36h-Stat4_MA0518.2 10 bp overlap
Stat5a 1 dataset
Motif DE_36h DE_36h-Stat5a_MA1624.2 9 bp overlap
Stat5a::Stat5b 1 dataset
Motif DE_36h DE_36h-Stat5aStat5b_MA0519.2 9 bp overlap
Stat5b 1 dataset
Motif DE_36h DE_36h-Stat5b_MA1625.2 9 bp overlap
Stat6 1 dataset
Motif DE_36h DE_36h-Stat6_MA0520.2 10 bp overlap
T 1 dataset
ChIP H9_MESODERM GSE60606.T.H9_MESODERM 189 bp overlap
TBP 1 dataset
Motif DE_60h DE_60h-TBP_MA0108.3 7 bp overlap
TBX2 1 dataset
ChIP Kelly GSE94822.TBX2.Kelly 270 bp overlap
TBX5 3 datasets
Motif DE_12h DE_12h-TBX5_MA0807.1 8 bp overlap
Motif DE_36h DE_36h-TBX5_MA0807.1 8 bp overlap
Motif DE_60h DE_60h-TBX5_MA0807.1 8 bp overlap
TCF12 4 datasets
Motif DE_12h DE_12h-TCF12_MA1648.2 7 bp overlap
Motif DE_36h DE_36h-TCF12_MA1648.2 7 bp overlap
ChIP H1 ENCFF203EBH 251 bp overlap
ChIP WA01 ENCSR000BIT.TCF12.WA01 304 bp overlap
TCF3 3 datasets
Motif DE_12h DE_12h-TCF3_MA0522.4 7 bp overlap
Motif DE_36h DE_36h-TCF3_MA0522.4 7 bp overlap
ChIP NPC GSE154479.TCF3.NPC 485 bp overlap
TCF4 1 dataset
Motif DE_36h DE_36h-TCF4_MA0830.3 8 bp overlap
TEAD4 2 datasets
ChIP BE2C GSE84389.TEAD4.BE2C 194 bp overlap
ChIP SK-N-BE2 GSE84389.TEAD4.SK-N-BE2 194 bp overlap
TGIF2 1 dataset
ChIP K562 ENCFF931EYZ 215 bp overlap
TRPS1 1 dataset
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
TWIST1 2 datasets
ChIP SHEP-21N GSE80151.TWIST1.SHEP-21N 310 bp overlap
ChIP SHEP-21N_DOX_0H GSE80151.TWIST1.SHEP-21N_DOX_0H 251 bp overlap
Tcf12 1 dataset
Motif DE_12h DE_12h-Tcf12_MA0521.3 6 bp overlap
Twist2 1 dataset
Motif DE_12h DE_12h-Twist2_MA0633.3 6 bp overlap
USF1 1 dataset
ChIP WA01 ENCSR000BIU.USF1.WA01 173 bp overlap
ZBTB12 1 dataset
Motif DE_12h DE_12h-ZBTB12_MA1649.2 7 bp overlap
ZEB1 7 datasets
Motif DE_12h DE_12h-ZEB1_MA0103.4 6 bp overlap
Motif DE_12h DE_12h-ZEB1_MA0103.4 6 bp overlap
Motif DE_36h DE_36h-ZEB1_MA0103.4 6 bp overlap
Motif DE_36h DE_36h-ZEB1_MA0103.4 6 bp overlap
Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap
Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap
Motif DE_72h DE_72h-ZEB1_MA0103.4 6 bp overlap
ZIM3 1 dataset
Motif DE_12h DE_12h-ZIM3_MA1709.2 11 bp overlap
ZKSCAN5 1 dataset
Motif DE_60h DE_60h-ZKSCAN5_MA1652.2 9 bp overlap
ZNF143 2 datasets
ChIP K-562 GSE39263.ZNF143.K-562 179 bp overlap
ChIP K-562 GSE39263.ZNF143.K-562 179 bp overlap
ZNF175 1 dataset
Motif DE_12h DE_12h-ZNF175_MA2332.1 9 bp overlap
ZNF257 1 dataset
Motif DE_60h DE_60h-ZNF257_MA1710.2 10 bp overlap
ZNF274 1 dataset
Motif DE_60h DE_60h-ZNF274_MA1592.2 12 bp overlap
ZNF331 3 datasets
Motif DE_36h DE_36h-ZNF331_MA1726.2 10 bp overlap
Motif DE_60h DE_60h-ZNF331_MA1726.2 10 bp overlap
Motif DE_72h DE_72h-ZNF331_MA1726.2 10 bp overlap
ZNF418 3 datasets
Motif DE_36h DE_36h-ZNF418_MA1980.1 15 bp overlap
Motif DE_60h DE_60h-ZNF418_MA1980.1 15 bp overlap
Motif DE_72h DE_72h-ZNF418_MA1980.1 15 bp overlap
ZNF462 1 dataset
ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 170 bp overlap
ZNF667 3 datasets
Motif DE_12h DE_12h-ZNF667_MA1984.2 11 bp overlap
Motif DE_36h DE_36h-ZNF667_MA1984.2 11 bp overlap
Motif DE_60h DE_60h-ZNF667_MA1984.2 11 bp overlap
ZNF708 1 dataset
Motif DE_60h DE_60h-ZNF708_MA1730.2 9 bp overlap
ZSCAN16 3 datasets
Motif DE_12h DE_12h-ZSCAN16_MA2100.1 18 bp overlap
Motif DE_36h DE_36h-ZSCAN16_MA2100.1 18 bp overlap
Motif DE_60h DE_60h-ZSCAN16_MA2100.1 18 bp overlap
Zic1::Zic2 2 datasets
Motif DE_12h DE_12h-Zic1Zic2_MA1628.2 7 bp overlap
Motif DE_60h DE_60h-Zic1Zic2_MA1628.2 7 bp overlap
Zic3 2 datasets
Motif DE_12h DE_12h-Zic3_MA0697.3 7 bp overlap
Motif DE_60h DE_60h-Zic3_MA0697.3 7 bp overlap
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