chr12 : 22,915,885 – 22,917,073
1,188 bp 125 TFs 3 linked genes
This 1.2 kb open chromatin element is linked to ENSG00000256923, LINC02955, and ETNK1 and is bound by 125 transcription factors.
Linked Genes
3 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ENSG00000256923 173.8 kb Distal Multiome
LINC02955 216.4 kb Distal Multiome
ETNK1 291.2 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr12:22,910,885 – 22,922,073
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
125 transcription factors
Source
Cell type
AR 1 dataset
ChIP LNCaP_1F5_SIFOXA1 GSE30623.AR.LNCaP_1F5_SIFOXA1 132 bp overlap
Alx1 1 dataset
Motif DE_36h DE_36h-Alx1_MA0854.2 8 bp overlap
Alx4 1 dataset
Motif DE_36h DE_36h-Alx4_MA0853.2 12 bp overlap
Ar 3 datasets
Motif DE_24h DE_24h-Ar_MA0007.4 16 bp overlap
Motif DE_48h DE_48h-Ar_MA0007.4 16 bp overlap
Motif DE_60h DE_60h-Ar_MA0007.4 16 bp overlap
Arid3a 1 dataset
Motif DE_36h DE_36h-Arid3a_MA0151.1 6 bp overlap
Arx 1 dataset
Motif DE_36h DE_36h-Arx_MA0874.2 10 bp overlap
Atf3 1 dataset
Motif DE_36h DE_36h-Atf3_MA1988.2 7 bp overlap
BACH1 1 dataset
Motif DE_36h DE_36h-BACH1_MA1633.2 9 bp overlap
BARX1 1 dataset
Motif DE_36h DE_36h-BARX1_MA0875.2 6 bp overlap
BATF 1 dataset
Motif DE_36h DE_36h-BATF_MA1634.2 7 bp overlap
BATF3 1 dataset
Motif DE_36h DE_36h-BATF3_MA0835.3 7 bp overlap
BATF::JUN 1 dataset
Motif DE_36h DE_36h-BATFJUN_MA0462.3 7 bp overlap
BNC2 1 dataset
Motif DE_36h DE_36h-BNC2_MA1928.2 7 bp overlap
BRD3 2 datasets
ChIP H-1_DE GSE126661.BRD3.H-1_DE 469 bp overlap
ChIP H-1_DE GSE126661.BRD3.H-1_DE 139 bp overlap
BRD4 1 dataset
ChIP LNCaP-C4-2_OE GSE88871.BRD4.LNCaP-C4-2_OE 52 bp overlap
BSX 1 dataset
Motif DE_36h DE_36h-BSX_MA0876.2 6 bp overlap
CBX8 1 dataset
ChIP K-562 ENCSR000ATW.CBX8.K-562 263 bp overlap
CHD2 1 dataset
ChIP K562 ENCFF857WME 327 bp overlap
CHD7 2 datasets
ChIP hiPSC_AF22_abD3F5 GSE108506.CHD7.hiPSC_AF22_abD3F5 479 bp overlap
ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 697 bp overlap
CTCF 2 datasets
Motif DE_24h DE_24h-CTCF_MA1930.2 33 bp overlap
Motif DE_48h DE_48h-CTCF_MA1930.2 33 bp overlap
DLX1 1 dataset
Motif DE_36h DE_36h-DLX1_MA0879.3 6 bp overlap
DLX6 1 dataset
Motif DE_36h DE_36h-DLX6_MA0882.2 6 bp overlap
DMRTC2 3 datasets
Motif DE_24h DE_24h-DMRTC2_MA1479.2 11 bp overlap
Motif DE_48h DE_48h-DMRTC2_MA1479.2 11 bp overlap
Motif DE_60h DE_60h-DMRTC2_MA1479.2 11 bp overlap
Dlx3 1 dataset
Motif DE_36h DE_36h-Dlx3_MA0880.2 6 bp overlap
Dlx4 1 dataset
Motif DE_36h DE_36h-Dlx4_MA0881.2 6 bp overlap
Dux 1 dataset
Motif DE_36h DE_36h-Dux_MA0611.3 11 bp overlap
E2F6 2 datasets
ChIP H1 ENCFF785DWK 451 bp overlap
ChIP WA01 ENCSR000BSI.E2F6.WA01 266 bp overlap
EBF1 3 datasets
Motif DE_36h DE_36h-EBF1_MA0154.5 11 bp overlap
Motif DE_48h DE_48h-EBF1_MA0154.5 11 bp overlap
Motif DE_60h DE_60h-EBF1_MA0154.5 11 bp overlap
EBF3 2 datasets
Motif DE_48h DE_48h-EBF3_MA1637.2 9 bp overlap
Motif DE_60h DE_60h-EBF3_MA1637.2 9 bp overlap
EOMES 3 datasets
Motif DE_48h DE_48h-EOMES_MA0800.2 9 bp overlap
Motif DE_60h DE_60h-EOMES_MA0800.2 9 bp overlap
ChIP hESC GSE26097.EOMES.hESC 493 bp overlap
EP300 1 dataset
ChIP hESC GSE17917.EP300.hESC 293 bp overlap
ERG 1 dataset
ChIP VCaP_DHAT_18H GSE28950.ERG.VCaP_DHAT_18H 123 bp overlap
ESR1 1 dataset
Motif DE_60h DE_60h-ESR1_MA0112.4 15 bp overlap
ETV1 1 dataset
ChIP MDA-Pca-2b GSE106624.ETV1.MDA-Pca-2b 96 bp overlap
ETV7 1 dataset
Motif DE_36h DE_36h-ETV7_MA1708.2 9 bp overlap
EZH2 1 dataset
ChIP LNCaP-abl GSE39459.EZH2.LNCaP-abl 258 bp overlap
Ebf2 2 datasets
Motif DE_48h DE_48h-Ebf2_MA1604.2 9 bp overlap
Motif DE_60h DE_60h-Ebf2_MA1604.2 9 bp overlap
Ebf4 3 datasets
Motif DE_36h DE_36h-Ebf4_MA2122.1 11 bp overlap
Motif DE_48h DE_48h-Ebf4_MA2122.1 11 bp overlap
Motif DE_60h DE_60h-Ebf4_MA2122.1 11 bp overlap
FIGLA 2 datasets
Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap
Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap
FLI1 3 datasets
ChIP A-673_1_KRAB_GFP GSE106914.FLI1.A-673_1_KRAB_GFP 642 bp overlap
ChIP A-673_2_KRAB_eSOX2_1 GSE106914.FLI1.A-673_2_KRAB_eSOX2_1 465 bp overlap
ChIP A-673_D17 GSE129155.FLI1.A-673_D17 514 bp overlap
FOS 1 dataset
Motif DE_36h DE_36h-FOS_MA0476.2 8 bp overlap
FOSL1 1 dataset
Motif DE_36h DE_36h-FOSL1_MA0477.3 9 bp overlap
FOXA1 1 dataset
ChIP breast-cancer_heregulin GSE101407.FOXA1.breast-cancer_heregulin 304 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 938 bp overlap
ChIP DE DE-FOXA2-2 737 bp overlap
Foxl2 3 datasets
Motif DE_24h DE_24h-Foxl2_MA1607.2 10 bp overlap
Motif DE_48h DE_48h-Foxl2_MA1607.2 10 bp overlap
Motif DE_60h DE_60h-Foxl2_MA1607.2 10 bp overlap
GATA4 2 datasets
ChIP DE DE-GATA4-1 828 bp overlap
ChIP DE DE-GATA4-2 892 bp overlap
GATA6 9 datasets
ChIP DE DE-GATA6-1 865 bp overlap
ChIP DE DE-GATA6-2 820 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 341 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 765 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 703 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 1168 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 592 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 737 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 433 bp overlap
GBX2 1 dataset
Motif DE_36h DE_36h-GBX2_MA0890.2 6 bp overlap
GLIS1 1 dataset
ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 219 bp overlap
HESX1 1 dataset
Motif DE_36h DE_36h-HESX1_MA0894.2 6 bp overlap
HOXA7 1 dataset
Motif DE_36h DE_36h-HOXA7_MA1498.3 6 bp overlap
HOXB13 1 dataset
Motif DE_36h DE_36h-HOXB13_MA0901.3 9 bp overlap
Hmx1 1 dataset
Motif DE_36h DE_36h-Hmx1_MA0896.2 9 bp overlap
Hmx3 1 dataset
Motif DE_36h DE_36h-Hmx3_MA0898.2 9 bp overlap
JUN 3 datasets
ChIP DE_D1 S40-DE-d1-JUN-exp2 814 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 584 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 655 bp overlap
Jun 1 dataset
Motif DE_36h DE_36h-Jun_MA0489.3 8 bp overlap
LBX2 1 dataset
Motif DE_36h DE_36h-LBX2_MA0699.2 6 bp overlap
LHX2 1 dataset
Motif DE_36h DE_36h-LHX2_MA0700.3 6 bp overlap
MAX 1 dataset
ChIP WA01 ENCSR000EUP.MAX.WA01 138 bp overlap
MGA 3 datasets
Motif DE_36h DE_36h-MGA_MA0801.1 8 bp overlap
Motif DE_48h DE_48h-MGA_MA0801.1 8 bp overlap
Motif DE_60h DE_60h-MGA_MA0801.1 8 bp overlap
MSC 2 datasets
Motif DE_48h DE_48h-MSC_MA0665.1 10 bp overlap
Motif DE_60h DE_60h-MSC_MA0665.1 10 bp overlap
MSX1 1 dataset
Motif DE_36h DE_36h-MSX1_MA0666.3 6 bp overlap
MSX2 1 dataset
Motif DE_36h DE_36h-MSX2_MA0708.3 6 bp overlap
MXI1 1 dataset
Motif DE_36h DE_36h-MXI1_MA1108.3 6 bp overlap
MYF6 2 datasets
Motif DE_48h DE_48h-MYF6_MA0667.1 10 bp overlap
Motif DE_60h DE_60h-MYF6_MA0667.1 10 bp overlap
MYOD1 2 datasets
Motif DE_48h DE_48h-MYOD1_MA0499.3 9 bp overlap
Motif DE_60h DE_60h-MYOD1_MA0499.3 9 bp overlap
Msx3 1 dataset
Motif DE_36h DE_36h-Msx3_MA0709.2 6 bp overlap
NANOG 3 datasets
ChIP HUES-8 GSE109524.NANOG.HUES-8 477 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 517 bp overlap
ChIP hESC GSE18292.NANOG.hESC 114 bp overlap
NCOR1 1 dataset
ChIP LS180 GSE39277.NCOR1.LS180 93 bp overlap
NR3C1 1 dataset
ChIP HeLa-B2_GRKD_TA_TNFA GSE24518.NR3C1.HeLa-B2_GRKD_TA_TNFA 171 bp overlap
Nobox 1 dataset
Motif DE_36h DE_36h-Nobox_MA0125.2 6 bp overlap
PHOX2A 1 dataset
Motif DE_36h DE_36h-PHOX2A_MA0713.1 11 bp overlap
PHOX2B 1 dataset
Motif DE_36h DE_36h-PHOX2B_MA0681.3 12 bp overlap
POU2F2 1 dataset
Motif DE_36h DE_36h-POU2F2_MA0507.3 13 bp overlap
POU3F3 1 dataset
Motif DE_36h DE_36h-POU3F3_MA0788.1 13 bp overlap
PROP1 1 dataset
Motif DE_36h DE_36h-PROP1_MA0715.1 11 bp overlap
Ptf1A 2 datasets
Motif DE_48h DE_48h-Ptf1A_MA1620.2 8 bp overlap
Motif DE_60h DE_60h-Ptf1A_MA1620.2 8 bp overlap
RAX 1 dataset
Motif DE_36h DE_36h-RAX_MA0718.2 6 bp overlap
RBBP5 1 dataset
ChIP WA01 ENCSR000AQC.RBBP5.WA01 145 bp overlap
REST 2 datasets
Motif DE_48h DE_48h-REST_MA0138.3 20 bp overlap
Motif DE_60h DE_60h-REST_MA0138.3 20 bp overlap
RUNX1 1 dataset
ChIP NB4 GSE81992.RUNX1.NB4 345 bp overlap
RUNX1T1 1 dataset
ChIP Kasumi-1 GSE102697.RUNX1T1.Kasumi-1 198 bp overlap
SCRT1 2 datasets
Motif DE_48h DE_48h-SCRT1_MA0743.3 10 bp overlap
Motif DE_60h DE_60h-SCRT1_MA0743.3 10 bp overlap
SCRT2 2 datasets
Motif DE_48h DE_48h-SCRT2_MA0744.3 10 bp overlap
Motif DE_60h DE_60h-SCRT2_MA0744.3 10 bp overlap
SMAD2 2 datasets
ChIP endoderm GSE29422.SMAD2.endoderm 241 bp overlap
ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 266 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 1188 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 1179 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 1188 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 1011 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 1078 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 1142 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 1188 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 1182 bp overlap
SMAD3 1 dataset
ChIP BG03_DIFF_48H GSE36578.SMAD3.BG03_DIFF_48H 210 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 172 bp overlap
SMARCA4 1 dataset
ChIP hiPSC GSE124903.SMARCA4.hiPSC 825 bp overlap
SMARCB1 1 dataset
ChIP hiPSC GSE124903.SMARCB1.hiPSC 225 bp overlap
SMARCC1 1 dataset
ChIP hiPSC GSE124903.SMARCC1.hiPSC 543 bp overlap
SNAI2 2 datasets
Motif DE_48h DE_48h-SNAI2_MA0745.3 8 bp overlap
Motif DE_60h DE_60h-SNAI2_MA0745.3 8 bp overlap
SNAI3 2 datasets
Motif DE_48h DE_48h-SNAI3_MA1559.2 9 bp overlap
Motif DE_60h DE_60h-SNAI3_MA1559.2 9 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 556 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 599 bp overlap
SOX2 3 datasets
ChIP HNSC GSE69479.SOX2.HNSC 402 bp overlap
ChIP HNSC GSE69479.SOX2.HNSC 106 bp overlap
ChIP hESC GSE18292.SOX2.hESC 105 bp overlap
SP5 3 datasets
Motif DE_36h DE_36h-SP5_MA1965.2 6 bp overlap
Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap
Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap
SPIB 2 datasets
Motif DE_36h DE_36h-SPIB_MA0081.3 13 bp overlap
ChIP OCI-Ly3_SHCTR GSE56857.SPIB.OCI-Ly3_SHCTR 175 bp overlap
STAT1::STAT2 3 datasets
Motif DE_36h DE_36h-STAT1STAT2_MA0517.2 13 bp overlap
Motif DE_48h DE_48h-STAT1STAT2_MA0517.2 13 bp overlap
Motif DE_60h DE_60h-STAT1STAT2_MA0517.2 13 bp overlap
Stat6 3 datasets
Motif DE_36h DE_36h-Stat6_MA0520.2 10 bp overlap
Motif DE_48h DE_48h-Stat6_MA0520.2 10 bp overlap
Motif DE_60h DE_60h-Stat6_MA0520.2 10 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 222 bp overlap
TBR1 2 datasets
Motif DE_48h DE_48h-TBR1_MA0802.2 9 bp overlap
Motif DE_60h DE_60h-TBR1_MA0802.2 9 bp overlap
TBX1 3 datasets
Motif DE_36h DE_36h-TBX1_MA0805.1 8 bp overlap
Motif DE_48h DE_48h-TBX1_MA0805.1 8 bp overlap
Motif DE_60h DE_60h-TBX1_MA0805.1 8 bp overlap
TBX15 3 datasets
Motif DE_36h DE_36h-TBX15_MA0803.1 8 bp overlap
Motif DE_48h DE_48h-TBX15_MA0803.1 8 bp overlap
Motif DE_60h DE_60h-TBX15_MA0803.1 8 bp overlap
TBX18 3 datasets
Motif DE_36h DE_36h-TBX18_MA1565.2 9 bp overlap
Motif DE_48h DE_48h-TBX18_MA1565.2 9 bp overlap
Motif DE_60h DE_60h-TBX18_MA1565.2 9 bp overlap
TBX2 2 datasets
Motif DE_48h DE_48h-TBX2_MA0688.2 9 bp overlap
Motif DE_60h DE_60h-TBX2_MA0688.2 9 bp overlap
TBX20 2 datasets
Motif DE_48h DE_48h-TBX20_MA0689.1 11 bp overlap
Motif DE_60h DE_60h-TBX20_MA0689.1 11 bp overlap
TBX21 2 datasets
Motif DE_48h DE_48h-TBX21_MA0690.3 10 bp overlap
Motif DE_60h DE_60h-TBX21_MA0690.3 10 bp overlap
TBX3 2 datasets
Motif DE_48h DE_48h-TBX3_MA1566.3 9 bp overlap
Motif DE_60h DE_60h-TBX3_MA1566.3 9 bp overlap
TBX4 3 datasets
Motif DE_36h DE_36h-TBX4_MA0806.1 8 bp overlap
Motif DE_48h DE_48h-TBX4_MA0806.1 8 bp overlap
Motif DE_60h DE_60h-TBX4_MA0806.1 8 bp overlap
TBX5 2 datasets
Motif DE_48h DE_48h-TBX5_MA0807.1 8 bp overlap
Motif DE_60h DE_60h-TBX5_MA0807.1 8 bp overlap
TCF3 1 dataset
ChIP NPC GSE154479.TCF3.NPC 378 bp overlap
TRIM28 1 dataset
ChIP hESC GSE115387.TRIM28.hESC 205 bp overlap
Tbx6 4 datasets
Motif DE_48h DE_48h-Tbx6_MA1567.3 9 bp overlap
Motif DE_48h DE_48h-Tbx6_MA1567.3 9 bp overlap
Motif DE_60h DE_60h-Tbx6_MA1567.3 9 bp overlap
Motif DE_60h DE_60h-Tbx6_MA1567.3 9 bp overlap
ZEB1 2 datasets
Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap
Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap
ZIC2 1 dataset
ChIP HEK293 ENCFF033NQQ 471 bp overlap
ZIM3 1 dataset
Motif DE_36h DE_36h-ZIM3_MA1709.2 11 bp overlap
ZNF140 2 datasets
Motif DE_48h DE_48h-ZNF140_MA1589.2 19 bp overlap
Motif DE_60h DE_60h-ZNF140_MA1589.2 19 bp overlap
ZNF207 1 dataset
ChIP WA09 GSE118632.ZNF207.WA09 253 bp overlap
ZNF263 3 datasets
Motif DE_36h DE_36h-ZNF263_MA0528.3 7 bp overlap
Motif DE_48h DE_48h-ZNF263_MA0528.3 7 bp overlap
Motif DE_60h DE_60h-ZNF263_MA0528.3 7 bp overlap
ZNF343 1 dataset
Motif DE_36h DE_36h-ZNF343_MA1711.2 16 bp overlap
ZNF530 2 datasets
Motif DE_48h DE_48h-ZNF530_MA1981.2 14 bp overlap
Motif DE_60h DE_60h-ZNF530_MA1981.2 14 bp overlap
ZNF75A 2 datasets
Motif DE_48h DE_48h-ZNF75A_MA2097.1 12 bp overlap
Motif DE_60h DE_60h-ZNF75A_MA2097.1 12 bp overlap
ZNF816 1 dataset
Motif DE_60h DE_60h-ZNF816_MA1719.2 15 bp overlap
Huangfu Lab · Publications · Resources · Contact