chr10:73,994,650–73,995,392

chr10 : 73,994,650 – 73,995,392

742 bp 69 TFs 12 linked genes

This 742 bp open chromatin element is linked to 12 target genes and is bound by 69 transcription factors.

Linked Genes

12 genes

Gene	Expression	Dist. to TSS	Distance	Link type
VCL		2.7 kb	Proximal	Proximity
PLAU		84.0 kb	Distal	Multiome
CAMK2G		120.6 kb	Distal	Multiome
AP3M1		155.7 kb	Distal	Multiome
ADK		156.1 kb	Distal	Multiome
NDST2		183.3 kb	Distal	Multiome
ZSWIM8		209.5 kb	Distal	Multiome
CHCHD1		213.1 kb	Distal	Multiome
FUT11		222.9 kb	Distal	Multiome
SEC24C		250.8 kb	Distal	Multiome
GLUD1P3		264.6 kb	Distal	Multiome
ENSG00000290737		264.7 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

69 transcription factors

ChIP LNCaP GSE80256.AR.LNCaP 197 bp overlap

ChIP K562 ENCFF687QUE 315 bp overlap

ChIP K562 ENCFF343XWA 73 bp overlap

ChIP K-562_DMSO GSE138084.BRD2.K-562_DMSO 243 bp overlap

BRD3 2 datasets

ChIP K-562_DMSO-IFNG GSE138084.BRD3.K-562_DMSO-IFNG 234 bp overlap

ChIP K-562_iBET-BD2-IFNG GSE138084.BRD3.K-562_iBET-BD2-IFNG 262 bp overlap

BRD4 2 datasets

ChIP K-562_iBET-BD2-IFNG GSE138084.BRD4.K-562_iBET-BD2-IFNG 284 bp overlap

ChIP K-562_iBET-IFNG GSE138084.BRD4.K-562_iBET-IFNG 196 bp overlap

ChIP G-401 GSE120234.BRD9.G-401 311 bp overlap

ChIP retina_Hu20 GSE137311.CRX.retina_Hu20 371 bp overlap

ChIP retina_Hu21 GSE137311.CRX.retina_Hu21 324 bp overlap

ChIP retina_Hu3 GSE137311.CRX.retina_Hu3 428 bp overlap

ChIP retina_Hu6 GSE137311.CRX.retina_Hu6 507 bp overlap

CTCF 3 datasets

ChIP retina_Hu22 GSE137311.CTCF.retina_Hu22 237 bp overlap

ChIP retina_Hu25 GSE137311.CTCF.retina_Hu25 331 bp overlap

ChIP retina_Hu6 GSE137311.CTCF.retina_Hu6 351 bp overlap

ChIP WA01 GSE94322.DUX4.WA01 205 bp overlap

ChIP K562 ENCFF622HMZ 426 bp overlap

EBF1 2 datasets

ChIP GM12878 ENCFF167CZS 291 bp overlap

ChIP NALM-6 GSE126300.EBF1.NALM-6 242 bp overlap

EGR1 3 datasets

ChIP K-562 ENCSR000BNE.EGR1.K-562 168 bp overlap

ChIP K562 ENCFF006PJY 245 bp overlap

ChIP K562 ENCFF895KGN 385 bp overlap

ChIP K562 ENCFF245JDF 333 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 459 bp overlap

FOSL1 1 dataset

ChIP K562 ENCFF455MKD 536 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 506 bp overlap

ChIP DE DE-FOXA2-2 456 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 570 bp overlap

ChIP DE DE-GATA4-2 595 bp overlap

GATA6 9 datasets

ChIP DE DE-GATA6-1 579 bp overlap

ChIP DE DE-GATA6-2 597 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 365 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 413 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 281 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 564 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 439 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 442 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 609 bp overlap

GATAD2A 1 dataset

ChIP K562 ENCFF071LJW 345 bp overlap

GLIS1 2 datasets

ChIP HEK293 ENCFF299RSE 457 bp overlap

ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 393 bp overlap

HDAC1 2 datasets

ChIP K-562 ENCSR387UWP.HDAC1.K-562 377 bp overlap

ChIP K562 ENCFF928TKZ 154 bp overlap

ChIP K562 ENCFF195BET 131 bp overlap

HMBOX1 3 datasets

ChIP K-562 ENCSR757IIU.HMBOX1.K-562 146 bp overlap

ChIP K562 ENCFF055GAZ 531 bp overlap

ChIP K562 ENCFF317JJX 521 bp overlap

HOXB13 1 dataset

ChIP G-401 GSE65381.HOXB13.G-401 719 bp overlap

ChIP K-562 ENCSR005NMT.ID3.K-562 317 bp overlap

IKZF1 2 datasets

ChIP K-562 ENCSR395HWC.IKZF1.K-562 575 bp overlap

ChIP K562 ENCFF771OHZ 421 bp overlap

INTS13 1 dataset

ChIP HL-60_PMA GSE106359.INTS13.HL-60_PMA 197 bp overlap

JMJD1C 1 dataset

ChIP NB4 GSE63484.JMJD1C.NB4 235 bp overlap

ChIP DE_D2 S54-DE-d2-JUN-exp2 435 bp overlap

ChIP K562 ENCFF336RCR 461 bp overlap

MEF2D 3 datasets

ChIP retina_Hu13 GSE137311.MEF2D.retina_Hu13 363 bp overlap

ChIP retina_Hu21 GSE137311.MEF2D.retina_Hu21 371 bp overlap

ChIP retina_Hu25 GSE137311.MEF2D.retina_Hu25 438 bp overlap

ChIP 501-mel GSE137522.MITF.501-mel 276 bp overlap

NCOR1 1 dataset

ChIP K562 ENCFF359DNT 130 bp overlap

NEUROD1 5 datasets

ChIP D283-Med GSE92582.NEUROD1.D283-Med 585 bp overlap

ChIP D283-Med_shNEUROD1-1579 GSE92582.NEUROD1.D283-Med_shNEUROD1-1579 389 bp overlap

ChIP D341-Med_shGFP GSE92582.NEUROD1.D341-Med_shGFP 415 bp overlap

ChIP D341-Med_shNEUROD1-1154 GSE92582.NEUROD1.D341-Med_shNEUROD1-1154 285 bp overlap

ChIP D341-Med_shNEUROD1-1579 GSE92582.NEUROD1.D341-Med_shNEUROD1-1579 391 bp overlap

NR2F1 3 datasets

ChIP K-562 ENCSR970NKQ.NR2F1.K-562 406 bp overlap

ChIP K562 ENCFF221HJH 497 bp overlap

ChIP K562 ENCFF221HJH 497 bp overlap

NR2F2 1 dataset

ChIP K-562 ENCSR000BRS.NR2F2.K-562 182 bp overlap

NR2F6 1 dataset

ChIP K-562 ENCSR707QWA.NR2F6.K-562 268 bp overlap

ChIP retina_Hu13 GSE137311.NRL.retina_Hu13 384 bp overlap

ChIP retina_Hu7 GSE137311.OTX2.retina_Hu7 477 bp overlap

ChIP NALM-6 GSE126300.PAX5.NALM-6 360 bp overlap

ChIP HEK293_ab833 GSE101646.PHIP.HEK293_ab833 285 bp overlap

PRDM1 2 datasets

ChIP HEK293 ENCFF302TBP 339 bp overlap

ChIP HEK293 GSE76494.PRDM1.HEK293 166 bp overlap

PRDM6 2 datasets

ChIP HEK293 ENCFF283AJL 445 bp overlap

ChIP HEK293 ENCSR892QHR.PRDM6.HEK293 420 bp overlap

PSIP1 1 dataset

ChIP T-REx-293 GSE117155.PSIP1.T-REx-293 314 bp overlap

RAD21 1 dataset

ChIP HAP1 GSE152721.RAD21.HAP1 292 bp overlap

ChIP K562 ENCFF653BQJ 478 bp overlap

ChIP retina_Hu22 GSE137311.RORB.retina_Hu22 456 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 539 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 596 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 490 bp overlap

SMAD2_3 4 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 468 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 598 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 601 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 508 bp overlap

SMAD3 2 datasets

ChIP K562 ENCFF035HNX 288 bp overlap

ChIP K562 ENCFF035HNX 371 bp overlap

SMARCA4 1 dataset

ChIP K-562 ENCSR587OQL.SMARCA4.K-562 94 bp overlap

SMARCC1 2 datasets

ChIP G-401_Dox GSE71504.SMARCC1.G-401_Dox 282 bp overlap

ChIP G-401_NoDox GSE71504.SMARCC1.G-401_NoDox 275 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 352 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 427 bp overlap

STAT6 1 dataset

ChIP K562 ENCFF444HZW 417 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 296 bp overlap

XRCC5 1 dataset

ChIP K-562 GSE120104.XRCC5.K-562 280 bp overlap

ZBTB20 1 dataset

ChIP HEK293 ENCFF524ADK 204 bp overlap

ZBTB40 1 dataset

ChIP K-562 ENCSR237VLT.ZBTB40.K-562 218 bp overlap

ZBTB7A 1 dataset

ChIP K-562 GSE103445.ZBTB7A.K-562 315 bp overlap

ChIP HEK293 ENCSR417VWF.ZEB2.HEK293 189 bp overlap

ZFHX2 1 dataset

ChIP HEK293 ENCFF167TUA 213 bp overlap

ZNF24 1 dataset

ChIP K562 ENCFF877JCX 151 bp overlap

ZNF335 1 dataset

ChIP HEK293 ENCFF784SLD 147 bp overlap

ZNF460 1 dataset

ChIP HepG2 ENCFF007NNM 219 bp overlap

ZNF543 1 dataset

ChIP HEK293T GSE78099.ZNF543.HEK293T 156 bp overlap

ZNF592 1 dataset

ChIP K-562 ENCSR249BHQ.ZNF592.K-562 241 bp overlap

ZNF766 1 dataset

ChIP K562 ENCFF348LDO 581 bp overlap