chr7 : 36,045,836 – 36,046,420

584 bp 89 TFs 3 linked genes

This 584 bp open chromatin element is linked to EEPD1, SEPTIN7, and SEPTIN7-DT and is bound by 89 transcription factors.

Linked Genes

3 genes

Gene	Dist. to TSS	Distance	Link type
EEPD1	107.1 kb	Distal	Multiome+HiCAR
SEPTIN7	245.0 kb	Distal	Multiome
SEPTIN7-DT	245.2 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

89 transcription factors

ASCL1 1 dataset

ChIP NCI-H82 GSE69394.ASCL1.NCI-H82 246 bp overlap

Atf3 1 dataset

Motif DE_48h DE_48h-Atf3_MA1988.2 7 bp overlap

BACH1 1 dataset

Motif DE_48h DE_48h-BACH1_MA1633.2 9 bp overlap

BATF 1 dataset

Motif DE_48h DE_48h-BATF_MA1634.2 7 bp overlap

BATF3 1 dataset

Motif DE_48h DE_48h-BATF3_MA0835.3 7 bp overlap

BATF::JUN 1 dataset

Motif DE_48h DE_48h-BATFJUN_MA0462.3 7 bp overlap

BNC2 1 dataset

Motif DE_48h DE_48h-BNC2_MA1928.2 7 bp overlap

BRD4 4 datasets

ChIP SUM159PT_100nMtrametinib300nMJQ1_24h GSE87418.BRD4.SUM159PT_100nMtrametinib300nMJQ1_24h 106 bp overlap

ChIP SUM159PT_100nMtrametinib_24h GSE87418.BRD4.SUM159PT_100nMtrametinib_24h 396 bp overlap

ChIP SUM229PE_neg_30nMtrametinib_24h GSE87418.BRD4.SUM229PE_neg_30nMtrametinib_24h 253 bp overlap

ChIP THP-1_iBET-BD2 GSE138084.BRD4.THP-1_iBET-BD2 210 bp overlap

CEBPB 1 dataset

ChIP HFOB_DIFF GSE82295.CEBPB.HFOB_DIFF 106 bp overlap

CTCF 2 datasets

ChIP GSC23 GSE139416.CTCF.GSC23 274 bp overlap

ChIP gastroesophageal-sphincter ENCSR661XNQ.CTCF.gastroesophageal-sphincter 150 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF031ISE 279 bp overlap

DPRX 2 datasets

Motif DE_48h DE_48h-DPRX_MA1480.2 9 bp overlap

Motif DE_60h DE_60h-DPRX_MA1480.2 9 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 228 bp overlap

ERF::SREBF2 2 datasets

Motif DE_48h DE_48h-ERFSREBF2_MA1939.2 16 bp overlap

Motif DE_60h DE_60h-ERFSREBF2_MA1939.2 16 bp overlap

FEZF2 1 dataset

Motif DE_48h DE_48h-FEZF2_MA2341.1 8 bp overlap

FIGLA 1 dataset

Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap

GATA1::TAL1 2 datasets

Motif DE_48h DE_48h-GATA1TAL1_MA0140.3 17 bp overlap

Motif DE_60h DE_60h-GATA1TAL1_MA0140.3 17 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 434 bp overlap

ChIP DE DE-GATA4-2 278 bp overlap

GATA6 6 datasets

ChIP DE DE-GATA6-1 323 bp overlap

ChIP DE DE-GATA6-2 357 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 536 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 355 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 469 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 463 bp overlap

GFI1 1 dataset

Motif DE_48h DE_48h-GFI1_MA0038.3 11 bp overlap

Gfi1B 1 dataset

Motif DE_48h DE_48h-Gfi1B_MA0483.2 10 bp overlap

HIF1A 1 dataset

ChIP BEAS-2B_arsenic GSE145834.HIF1A.BEAS-2B_arsenic 252 bp overlap

IKZF1 2 datasets

ChIP GM12878 ENCFF753XDO 511 bp overlap

ChIP GM12878 ENCFF753XDO 462 bp overlap

IKZF2 1 dataset

ChIP GM12878 ENCSR680UQE.IKZF2.GM12878 324 bp overlap

IRF4 1 dataset

ChIP BC-3 GSE132777.IRF4.BC-3 569 bp overlap

Jun 1 dataset

Motif DE_48h DE_48h-Jun_MA0489.3 8 bp overlap

KAT7 1 dataset

ChIP OCI-AML-3 GSE133516.KAT7.OCI-AML-3 370 bp overlap

KDM4A 1 dataset

ChIP WA01 ENCSR000AVC.KDM4A.WA01 297 bp overlap

KLF11 2 datasets

Motif DE_12h DE_12h-KLF11_MA1512.2 10 bp overlap

Motif DE_48h DE_48h-KLF11_MA1512.2 10 bp overlap

KLF16 2 datasets

Motif DE_12h DE_12h-KLF16_MA0741.1 11 bp overlap

Motif DE_48h DE_48h-KLF16_MA0741.1 11 bp overlap

KLF5 2 datasets

Motif DE_12h DE_12h-KLF5_MA0599.1 10 bp overlap

Motif DE_48h DE_48h-KLF5_MA0599.1 10 bp overlap

KLF9 2 datasets

Motif DE_12h DE_12h-KLF9_MA1107.3 11 bp overlap

Motif DE_48h DE_48h-KLF9_MA1107.3 11 bp overlap

LIN54 1 dataset

Motif DE_48h DE_48h-LIN54_MA0619.2 7 bp overlap

MAF1 1 dataset

ChIP THP-1_monocytes GSE96800.MAF1.THP-1_monocytes 153 bp overlap

MAX 3 datasets

ChIP NCI-H2171 GSE41105.MAX.NCI-H2171 517 bp overlap

ChIP NCI-H2171 GSE36354.MAX.NCI-H2171 338 bp overlap

ChIP WTC11 ENCFF223QFY 512 bp overlap

MED1 5 datasets

ChIP SGBS GSE64233.MED1.SGBS 167 bp overlap

ChIP SGBS_TNF GSE64233.MED1.SGBS_TNF 99 bp overlap

ChIP hMSC-TERT4_adipocyte-D7 GSE113253.MED1.hMSC-TERT4_adipocyte-D7 93 bp overlap

ChIP hMSC-TERT4_osteoblast-D3 GSE113253.MED1.hMSC-TERT4_osteoblast-D3 140 bp overlap

ChIP hMSC-TERT4_osteoblast-D7 GSE113253.MED1.hMSC-TERT4_osteoblast-D7 83 bp overlap

MGA::EVX1 1 dataset

Motif DE_48h DE_48h-MGAEVX1_MA1960.2 11 bp overlap

MTA2 2 datasets

ChIP GM12878 ENCFF615CWQ 550 bp overlap

ChIP GM12878 ENCSR293QAR.MTA2.GM12878 350 bp overlap

MXI1 1 dataset

Motif DE_48h DE_48h-MXI1_MA1108.3 6 bp overlap

MYC 2 datasets

ChIP NCI-H128 GSE41105.MYC.NCI-H128 301 bp overlap

ChIP NCI-H2171 GSE36354.MYC.NCI-H2171 310 bp overlap

NANOG 4 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 461 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 312 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 129 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 184 bp overlap

NEUROD1 1 dataset

ChIP D341-Med_shGFP GSE92582.NEUROD1.D341-Med_shGFP 584 bp overlap

NFATC3 1 dataset

ChIP GM12878 ENCSR437GBJ.NFATC3.GM12878 333 bp overlap

NFYA 1 dataset

Motif DE_48h DE_48h-NFYA_MA0060.4 8 bp overlap

NFYB 2 datasets

Motif DE_48h DE_48h-NFYB_MA0502.3 9 bp overlap

ChIP K-562 ENCSR000EGQ.NFYB.K-562 176 bp overlap

NFYC 1 dataset

Motif DE_48h DE_48h-NFYC_MA1644.2 7 bp overlap

NIPBL 1 dataset

ChIP HEK293T_CRISPR-2 GSE122299.NIPBL.HEK293T_CRISPR-2 74 bp overlap

PAX3 1 dataset

Motif DE_48h DE_48h-PAX3_MA1546.2 14 bp overlap

PHF19 1 dataset

ChIP DU145_SH4 GSE135623.PHF19.DU145_SH4 366 bp overlap

PKNOX1 1 dataset

ChIP GM12878 ENCSR711XNY.PKNOX1.GM12878 173 bp overlap

POLR2A 1 dataset

ChIP vagina ENCFF384GAB 67 bp overlap

POU2F1 1 dataset

Motif DE_48h DE_48h-POU2F1_MA0785.2 9 bp overlap

POU5F1 1 dataset

ChIP HUES-8 GSE109524.POU5F1.HUES-8 392 bp overlap

POU5F1B 1 dataset

Motif DE_48h DE_48h-POU5F1B_MA0792.1 9 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 212 bp overlap

RELA 2 datasets

ChIP SGBS GSE64233.RELA.SGBS 87 bp overlap

ChIP SGBS_TNF GSE64233.RELA.SGBS_TNF 50 bp overlap

SIN3A 1 dataset

ChIP HUVEC-C GSE103245.SIN3A.HUVEC-C 286 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 407 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 448 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 307 bp overlap

SMAD2_3 3 datasets

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 272 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 465 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 246 bp overlap

SMAD3 2 datasets

ChIP BG03 GSE21614.SMAD3.BG03 213 bp overlap

ChIP BG03_DIFF_2H GSE36578.SMAD3.BG03_DIFF_2H 167 bp overlap

SMARCA4 1 dataset

ChIP 501-mel_SHSOX10 GSE61965.SMARCA4.501-mel_SHSOX10 316 bp overlap

SMARCC1 1 dataset

ChIP DE_D1 S15-DE-d1-BAF155-exp1 243 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 221 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 366 bp overlap

SP1 3 datasets

ChIP WA01 ENCSR000BIR.SP1.WA01 209 bp overlap

ChIP liver ENCFF597LFJ 85 bp overlap

ChIP liver ENCFF769YSM 136 bp overlap

SP3 2 datasets

Motif DE_12h DE_12h-SP3_MA0746.3 11 bp overlap

Motif DE_48h DE_48h-SP3_MA0746.3 11 bp overlap

SP8 2 datasets

Motif DE_12h DE_12h-SP8_MA0747.2 11 bp overlap

Motif DE_48h DE_48h-SP8_MA0747.2 11 bp overlap

SP9 2 datasets

Motif DE_12h DE_12h-SP9_MA1564.2 10 bp overlap

Motif DE_48h DE_48h-SP9_MA1564.2 10 bp overlap

SPIB 1 dataset

ChIP OCI-Ly3_SHSPIB GSE56857.SPIB.OCI-Ly3_SHSPIB 310 bp overlap

SREBF1 2 datasets

Motif DE_48h DE_48h-SREBF1_MA0829.3 10 bp overlap

Motif DE_60h DE_60h-SREBF1_MA0829.3 10 bp overlap

Stat2 1 dataset

Motif DE_48h DE_48h-Stat2_MA1623.2 10 bp overlap

TBP 1 dataset

ChIP hESC GSE122298.TBP.hESC 137 bp overlap

TBX21 1 dataset

ChIP GM12878 ENCSR739IHN.TBX21.GM12878 335 bp overlap

TCF12 1 dataset

ChIP WA01 ENCSR000BIT.TCF12.WA01 139 bp overlap

TCF3 1 dataset

ChIP NPC GSE154479.TCF3.NPC 350 bp overlap

USF1 2 datasets

Motif DE_48h DE_48h-USF1_MA0093.4 10 bp overlap

ChIP WA01 ENCSR000BIU.USF1.WA01 125 bp overlap

YY1 1 dataset

ChIP WA01 ENCSR000BKD.YY1.WA01 157 bp overlap

ZBTB6 1 dataset

Motif DE_48h DE_48h-ZBTB6_MA1581.2 9 bp overlap

ZEB1 1 dataset

Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap

ZNF135 1 dataset

Motif DE_48h DE_48h-ZNF135_MA1587.1 14 bp overlap

ZNF213 1 dataset

Motif DE_48h DE_48h-ZNF213_MA2121.1 12 bp overlap

ZNF282 2 datasets

Motif DE_12h DE_12h-ZNF282_MA1154.2 15 bp overlap

Motif DE_48h DE_48h-ZNF282_MA1154.2 15 bp overlap

ZNF423 1 dataset

ChIP WTC11 ENCFF574PBR 317 bp overlap

ZNF462 2 datasets

ChIP GM23338 ENCFF896CCA 251 bp overlap

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 367 bp overlap

ZNF530 1 dataset

Motif DE_12h DE_12h-ZNF530_MA1981.2 14 bp overlap

ZNF687 1 dataset

ChIP GM12878 ENCSR859FDL.ZNF687.GM12878 212 bp overlap

ZNF75D 1 dataset

Motif DE_48h DE_48h-ZNF75D_MA1601.2 12 bp overlap

ZNF768 1 dataset

Motif DE_48h DE_48h-ZNF768_MA1731.2 9 bp overlap

ZSCAN18 1 dataset

ChIP WTC11 ENCFF867QWX 257 bp overlap