chr4 : 122,466,594 – 122,467,333
739 bp 109 TFs 1 linked gene
This 739 bp open chromatin element is linked to IL2 and is bound by 109 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
IL2 9.9 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr4:122,461,594 – 122,472,333
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
109 transcription factors
Source
Cell type
BCL6 1 dataset
Motif DE_48h DE_48h-BCL6_MA0463.3 13 bp overlap
BRD4 1 dataset
ChIP MOLT-4_DMSO GSE79288.BRD4.MOLT-4_DMSO 77 bp overlap
CDK9 1 dataset
ChIP MOLT-4_JQ1 GSE79288.CDK9.MOLT-4_JQ1 107 bp overlap
DMRTA2 1 dataset
Motif DE_48h DE_48h-DMRTA2_MA1478.2 6 bp overlap
DUX4 2 datasets
Motif DE_48h DE_48h-DUX4_MA0468.1 11 bp overlap
ChIP WA01 GSE94322.DUX4.WA01 368 bp overlap
DUXA 1 dataset
Motif DE_48h DE_48h-DUXA_MA0884.2 13 bp overlap
Dux 1 dataset
Motif DE_48h DE_48h-Dux_MA0611.3 11 bp overlap
EHF 1 dataset
Motif DE_48h DE_48h-EHF_MA0598.4 9 bp overlap
ELF1 1 dataset
Motif DE_48h DE_48h-ELF1_MA0473.4 9 bp overlap
ELF3 1 dataset
Motif DE_48h DE_48h-ELF3_MA0640.3 9 bp overlap
EOMES 3 datasets
Motif DE_48h DE_48h-EOMES_MA0800.2 9 bp overlap
ChIP hESC GSE26097.EOMES.hESC 124 bp overlap
ChIP hESC GSE26097.EOMES.hESC 175 bp overlap
Elf5 1 dataset
Motif DE_48h DE_48h-Elf5_MA0136.4 8 bp overlap
FOXA2 3 datasets
ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.FOXA2.BJ1-hTERT_FOXA2_GATA4_Coexp 395 bp overlap
ChIP DE DE-FOXA2-1 564 bp overlap
ChIP DE DE-FOXA2-2 490 bp overlap
FOXN3 1 dataset
Motif DE_48h DE_48h-FOXN3_MA1489.1 8 bp overlap
FOXO6 1 dataset
Motif DE_48h DE_48h-FOXO6_MA0849.1 7 bp overlap
FOXP2 1 dataset
Motif DE_48h DE_48h-FOXP2_MA0593.2 9 bp overlap
GATA3 1 dataset
ChIP Jurkat GSE76181.GATA3.Jurkat 154 bp overlap
GATA4 3 datasets
ChIP DE DE-GATA4-1 560 bp overlap
ChIP DE DE-GATA4-2 591 bp overlap
ChIP foregut GSE117136.GATA4.foregut 451 bp overlap
GATA6 4 datasets
ChIP DE DE-GATA6-1 549 bp overlap
ChIP DE DE-GATA6-2 587 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 586 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 579 bp overlap
Hoxd13 1 dataset
Motif DE_48h DE_48h-Hoxd13_MA0909.4 7 bp overlap
IKZF2 1 dataset
Motif DE_48h DE_48h-IKZF2_MA2326.1 6 bp overlap
KLF10 1 dataset
Motif DE_48h DE_48h-KLF10_MA1511.2 9 bp overlap
KLF12 1 dataset
Motif DE_48h DE_48h-KLF12_MA0742.2 9 bp overlap
KLF14 1 dataset
Motif DE_48h DE_48h-KLF14_MA0740.2 9 bp overlap
KLF16 1 dataset
Motif DE_48h DE_48h-KLF16_MA0741.1 11 bp overlap
KLF5 1 dataset
Motif DE_48h DE_48h-KLF5_MA0599.1 10 bp overlap
LHX6 1 dataset
Motif DE_48h DE_48h-LHX6_MA0658.2 8 bp overlap
LMO1 1 dataset
ChIP Jurkat GSE94391.LMO1.Jurkat 59 bp overlap
MAFF 1 dataset
Motif DE_48h DE_48h-MAFF_MA0495.4 11 bp overlap
MAZ 1 dataset
Motif DE_48h DE_48h-MAZ_MA1522.2 8 bp overlap
MEIS1 2 datasets
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
MEIS2 2 datasets
Motif DE_48h DE_48h-MEIS2_MA0774.1 8 bp overlap
Motif DE_48h DE_48h-MEIS2_MA0774.1 8 bp overlap
MEIS3 2 datasets
Motif DE_48h DE_48h-MEIS3_MA0775.2 7 bp overlap
Motif DE_48h DE_48h-MEIS3_MA0775.2 7 bp overlap
MGA 1 dataset
Motif DE_48h DE_48h-MGA_MA0801.1 8 bp overlap
MYB 1 dataset
Motif DE_48h DE_48h-MYB_MA0100.4 6 bp overlap
MYBL1 1 dataset
Motif DE_48h DE_48h-MYBL1_MA0776.1 12 bp overlap
Mecom 1 dataset
Motif DE_48h DE_48h-Mecom_MA0029.2 11 bp overlap
NR2C2 1 dataset
Motif DE_48h DE_48h-NR2C2_MA0504.2 14 bp overlap
NRL 1 dataset
Motif DE_48h DE_48h-NRL_MA0842.3 12 bp overlap
Nfat5 1 dataset
Motif DE_48h DE_48h-Nfat5_MA0606.3 8 bp overlap
Nr2e1 1 dataset
Motif DE_48h DE_48h-Nr2e1_MA0676.1 9 bp overlap
OLIG2 1 dataset
Motif DE_48h DE_48h-OLIG2_MA0678.1 10 bp overlap
OLIG3 1 dataset
Motif DE_48h DE_48h-OLIG3_MA0827.1 10 bp overlap
ONECUT1 1 dataset
Motif DE_48h DE_48h-ONECUT1_MA0679.3 9 bp overlap
ONECUT3 1 dataset
Motif DE_48h DE_48h-ONECUT3_MA0757.2 12 bp overlap
PATZ1 1 dataset
Motif DE_48h DE_48h-PATZ1_MA1961.2 11 bp overlap
PGR 1 dataset
Motif DE_48h DE_48h-PGR_MA2327.1 9 bp overlap
PHOX2A 1 dataset
Motif DE_48h DE_48h-PHOX2A_MA0713.1 11 bp overlap
PHOX2B 1 dataset
Motif DE_48h DE_48h-PHOX2B_MA0681.3 12 bp overlap
POU1F1 1 dataset
Motif DE_48h DE_48h-POU1F1_MA0784.3 14 bp overlap
POU3F2 1 dataset
Motif DE_48h DE_48h-POU3F2_MA0787.1 12 bp overlap
POU3F3 1 dataset
Motif DE_48h DE_48h-POU3F3_MA0788.1 13 bp overlap
POU4F1 1 dataset
Motif DE_48h DE_48h-POU4F1_MA0790.2 12 bp overlap
POU4F3 1 dataset
Motif DE_48h DE_48h-POU4F3_MA0791.2 12 bp overlap
PPARA::RXRA 1 dataset
Motif DE_48h DE_48h-PPARARXRA_MA1148.2 17 bp overlap
PROP1 1 dataset
Motif DE_48h DE_48h-PROP1_MA0715.1 11 bp overlap
Pgr 1 dataset
Motif DE_48h DE_48h-Pgr_MA2323.1 17 bp overlap
Plagl1 1 dataset
Motif DE_48h DE_48h-Plagl1_MA1615.2 8 bp overlap
Pou5f1::Sox2 1 dataset
Motif DE_48h DE_48h-Pou5f1Sox2_MA0142.1 15 bp overlap
Pparg::Rxra 1 dataset
Motif DE_48h DE_48h-PpargRxra_MA0065.3 13 bp overlap
SCRT1 1 dataset
Motif DE_48h DE_48h-SCRT1_MA0743.3 10 bp overlap
SIX2 1 dataset
Motif DE_48h DE_48h-SIX2_MA1119.2 11 bp overlap
SMAD2-3 2 datasets
ChIP HGrC1_EV-TGF GSE138496.SMAD2-3.HGrC1_EV-TGF 126 bp overlap
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 254 bp overlap
SOX13 1 dataset
Motif DE_48h DE_48h-SOX13_MA1120.2 7 bp overlap
SOX14 1 dataset
Motif DE_48h DE_48h-SOX14_MA1562.2 9 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 506 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 261 bp overlap
SOX18 1 dataset
Motif DE_48h DE_48h-SOX18_MA1563.2 8 bp overlap
SOX2 1 dataset
Motif DE_48h DE_48h-SOX2_MA0143.5 7 bp overlap
SOX4 1 dataset
Motif DE_48h DE_48h-SOX4_MA0867.3 8 bp overlap
SOX8 2 datasets
Motif DE_48h DE_48h-SOX8_MA0868.3 7 bp overlap
Motif DE_48h DE_48h-SOX8_MA0868.3 7 bp overlap
SOX9 1 dataset
Motif DE_48h DE_48h-SOX9_MA0077.2 8 bp overlap
SP1 1 dataset
Motif DE_48h DE_48h-SP1_MA0079.5 9 bp overlap
SP2 1 dataset
Motif DE_48h DE_48h-SP2_MA0516.3 9 bp overlap
SP3 1 dataset
Motif DE_48h DE_48h-SP3_MA0746.3 11 bp overlap
SP4 1 dataset
Motif DE_48h DE_48h-SP4_MA0685.2 9 bp overlap
SP5 1 dataset
Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap
SPI1 1 dataset
ChIP CTV-1_FLAG_15perc GSE128835.SPI1.CTV-1_FLAG_15perc 182 bp overlap
SPIB 1 dataset
Motif DE_48h DE_48h-SPIB_MA0081.3 13 bp overlap
SRY 1 dataset
Motif DE_48h DE_48h-SRY_MA0084.2 7 bp overlap
Sox11 1 dataset
Motif DE_48h DE_48h-Sox11_MA0869.3 8 bp overlap
Sox17 1 dataset
Motif DE_48h DE_48h-Sox17_MA0078.3 10 bp overlap
Sox3 1 dataset
Motif DE_48h DE_48h-Sox3_MA0514.3 7 bp overlap
Sox5 1 dataset
Motif DE_48h DE_48h-Sox5_MA0087.3 8 bp overlap
Sox6 2 datasets
Motif DE_48h DE_48h-Sox6_MA0515.1 10 bp overlap
Motif DE_48h DE_48h-Sox6_MA0515.1 10 bp overlap
Sox7 2 datasets
Motif DE_48h DE_48h-Sox7_MA2095.1 10 bp overlap
Motif DE_48h DE_48h-Sox7_MA2095.1 10 bp overlap
Spi1 1 dataset
Motif DE_48h DE_48h-Spi1_MA0080.7 13 bp overlap
TBR1 1 dataset
Motif DE_48h DE_48h-TBR1_MA0802.2 9 bp overlap
TBX1 1 dataset
Motif DE_48h DE_48h-TBX1_MA0805.1 8 bp overlap
TBX15 1 dataset
Motif DE_48h DE_48h-TBX15_MA0803.1 8 bp overlap
TBX18 1 dataset
Motif DE_48h DE_48h-TBX18_MA1565.2 9 bp overlap
TBX2 1 dataset
Motif DE_48h DE_48h-TBX2_MA0688.2 9 bp overlap
TBX20 1 dataset
Motif DE_48h DE_48h-TBX20_MA0689.1 11 bp overlap
TBX21 1 dataset
Motif DE_48h DE_48h-TBX21_MA0690.3 10 bp overlap
TBX3 1 dataset
Motif DE_48h DE_48h-TBX3_MA1566.3 9 bp overlap
TBX4 1 dataset
Motif DE_48h DE_48h-TBX4_MA0806.1 8 bp overlap
Tbx6 1 dataset
Motif DE_48h DE_48h-Tbx6_MA1567.3 9 bp overlap
ZKSCAN3 1 dataset
Motif DE_48h DE_48h-ZKSCAN3_MA1973.2 14 bp overlap
ZNF148 1 dataset
Motif DE_48h DE_48h-ZNF148_MA1653.2 10 bp overlap
ZNF175 1 dataset
Motif DE_48h DE_48h-ZNF175_MA2332.1 9 bp overlap
ZNF211 1 dataset
Motif DE_48h DE_48h-ZNF211_MA1974.2 10 bp overlap
ZNF281 1 dataset
Motif DE_48h DE_48h-ZNF281_MA1630.3 10 bp overlap
ZNF324 1 dataset
Motif DE_48h DE_48h-ZNF324_MA1977.2 14 bp overlap
ZNF354A 3 datasets
Motif DE_48h DE_48h-ZNF354A_MA1978.2 20 bp overlap
Motif DE_48h DE_48h-ZNF354A_MA1978.2 20 bp overlap
Motif DE_60h DE_60h-ZNF354A_MA1978.2 20 bp overlap
ZNF530 1 dataset
Motif DE_48h DE_48h-ZNF530_MA1981.2 14 bp overlap
ZNF574 1 dataset
Motif DE_48h DE_48h-ZNF574_MA1982.2 14 bp overlap
ZNF677 1 dataset
Motif DE_48h DE_48h-ZNF677_MA2101.1 12 bp overlap
ZNF75A 1 dataset
Motif DE_48h DE_48h-ZNF75A_MA2097.1 12 bp overlap
ZSCAN16 1 dataset
Motif DE_48h DE_48h-ZSCAN16_MA2100.1 18 bp overlap
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