chr3 : 150,165,261 – 150,165,994
733 bp 106 TFs 3 linked genes
This 733 bp open chromatin element is linked to ENSG00000243944, PFN2, and TSC22D2 and is bound by 106 transcription factors.
Linked Genes
3 genes
Link type
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ENSG00000243944 126.5 kb Distal Multiome
PFN2 194.8 kb Distal Multiome+HiCAR
TSC22D2 242.6 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr3:150,160,261 – 150,170,994
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
106 transcription factors
Source
Cell type
BACH2 2 datasets
Motif DE_60h DE_60h-BACH2_MA1470.2 19 bp overlap
Motif DE_72h DE_72h-BACH2_MA1470.2 19 bp overlap
BRD4 2 datasets
ChIP RH4_shCHD4 GSE140115.BRD4.RH4_shCHD4 194 bp overlap
ChIP RH4_shscr GSE140115.BRD4.RH4_shscr 226 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF093OYK 251 bp overlap
DUX4 4 datasets
Motif DE_60h DE_60h-DUX4_MA0468.1 11 bp overlap
Motif DE_60h DE_60h-DUX4_MA0468.1 11 bp overlap
Motif DE_72h DE_72h-DUX4_MA0468.1 11 bp overlap
Motif DE_72h DE_72h-DUX4_MA0468.1 11 bp overlap
EOMES 1 dataset
Motif DE_48h DE_48h-EOMES_MA0800.2 9 bp overlap
ESR1 2 datasets
Motif DE_60h DE_60h-ESR1_MA0112.4 15 bp overlap
Motif DE_72h DE_72h-ESR1_MA0112.4 15 bp overlap
ESRRA 2 datasets
Motif DE_60h DE_60h-ESRRA_MA0592.4 9 bp overlap
Motif DE_72h DE_72h-ESRRA_MA0592.4 9 bp overlap
ESRRB 2 datasets
Motif DE_60h DE_60h-ESRRB_MA0141.4 10 bp overlap
Motif DE_72h DE_72h-ESRRB_MA0141.4 10 bp overlap
Esrrg 2 datasets
Motif DE_60h DE_60h-Esrrg_MA0643.2 9 bp overlap
Motif DE_72h DE_72h-Esrrg_MA0643.2 9 bp overlap
FOXA1 5 datasets
ChIP A-549 ENCSR000BPX.FOXA1.A-549 152 bp overlap
ChIP T-47D_JC4747 GSE126004.FOXA1.T-47D_JC4747 187 bp overlap
ChIP T-47D_shRNF2_24h GSE137579.FOXA1.T-47D_shRNF2_24h 176 bp overlap
ChIP T-47D_shRNF2_45min GSE137579.FOXA1.T-47D_shRNF2_45min 144 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.FOXA1.pancreatic-progenitor_PP1 236 bp overlap
FOXA2 5 datasets
ChIP DE DE-FOXA2-1 733 bp overlap
ChIP DE DE-FOXA2-2 722 bp overlap
Motif DE_60h DE_60h-FOXA2_MA0047.4 8 bp overlap
Motif DE_72h DE_72h-FOXA2_MA0047.4 8 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.FOXA2.pancreatic-progenitor_PP1 274 bp overlap
FOXA3 2 datasets
Motif DE_60h DE_60h-FOXA3_MA1683.2 7 bp overlap
Motif DE_72h DE_72h-FOXA3_MA1683.2 7 bp overlap
FOXB1 2 datasets
Motif DE_60h DE_60h-FOXB1_MA0845.1 11 bp overlap
Motif DE_72h DE_72h-FOXB1_MA0845.1 11 bp overlap
FOXC1 2 datasets
Motif DE_60h DE_60h-FOXC1_MA0032.2 11 bp overlap
Motif DE_72h DE_72h-FOXC1_MA0032.2 11 bp overlap
FOXC2 2 datasets
Motif DE_60h DE_60h-FOXC2_MA0846.2 11 bp overlap
Motif DE_72h DE_72h-FOXC2_MA0846.2 11 bp overlap
FOXD3 2 datasets
Motif DE_60h DE_60h-FOXD3_MA0041.3 14 bp overlap
Motif DE_72h DE_72h-FOXD3_MA0041.3 14 bp overlap
FOXI1 2 datasets
Motif DE_60h DE_60h-FOXI1_MA0042.2 7 bp overlap
Motif DE_72h DE_72h-FOXI1_MA0042.2 7 bp overlap
FOXN3 2 datasets
Motif DE_60h DE_60h-FOXN3_MA1489.1 8 bp overlap
Motif DE_72h DE_72h-FOXN3_MA1489.1 8 bp overlap
FOXP1 2 datasets
Motif DE_60h DE_60h-FOXP1_MA0481.4 7 bp overlap
Motif DE_72h DE_72h-FOXP1_MA0481.4 7 bp overlap
FOXP4 2 datasets
Motif DE_60h DE_60h-FOXP4_MA2117.1 7 bp overlap
Motif DE_72h DE_72h-FOXP4_MA2117.1 7 bp overlap
FOXS1 2 datasets
Motif DE_60h DE_60h-FOXS1_MA2118.1 8 bp overlap
Motif DE_72h DE_72h-FOXS1_MA2118.1 8 bp overlap
Foxj3 2 datasets
Motif DE_60h DE_60h-Foxj3_MA0851.2 9 bp overlap
Motif DE_72h DE_72h-Foxj3_MA0851.2 9 bp overlap
Foxl2 2 datasets
Motif DE_60h DE_60h-Foxl2_MA1607.2 10 bp overlap
Motif DE_72h DE_72h-Foxl2_MA1607.2 10 bp overlap
GATA4 5 datasets
ChIP DE DE-GATA4-1 606 bp overlap
ChIP DE DE-GATA4-2 626 bp overlap
ChIP foregut GSE117136.GATA4.foregut 387 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 453 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 410 bp overlap
GATA6 9 datasets
ChIP DE DE-GATA6-1 605 bp overlap
ChIP DE DE-GATA6-2 623 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 312 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 415 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 491 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 409 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 410 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 362 bp overlap
ChIP foregut GSE117136.GATA6.foregut 381 bp overlap
HDAC2 1 dataset
ChIP RH4_Entinostat-6H GSE116344.HDAC2.RH4_Entinostat-6H 173 bp overlap
HNF4A 1 dataset
Motif DE_60h DE_60h-HNF4A_MA0114.5 9 bp overlap
HNF4G 1 dataset
Motif DE_60h DE_60h-HNF4G_MA0484.3 9 bp overlap
HOXA4 2 datasets
Motif DE_60h DE_60h-HOXA4_MA1496.2 7 bp overlap
Motif DE_72h DE_72h-HOXA4_MA1496.2 7 bp overlap
HOXB4 2 datasets
Motif DE_60h DE_60h-HOXB4_MA1499.2 6 bp overlap
Motif DE_72h DE_72h-HOXB4_MA1499.2 6 bp overlap
HOXC4 2 datasets
Motif DE_60h DE_60h-HOXC4_MA1504.2 6 bp overlap
Motif DE_72h DE_72h-HOXC4_MA1504.2 6 bp overlap
HOXD4 2 datasets
Motif DE_60h DE_60h-HOXD4_MA1507.2 6 bp overlap
Motif DE_72h DE_72h-HOXD4_MA1507.2 6 bp overlap
KDM1A 1 dataset
ChIP pancreatic-progenitor_GT GSE104840.KDM1A.pancreatic-progenitor_GT 324 bp overlap
KDM4A 1 dataset
ChIP WA01 ENCSR000AVC.KDM4A.WA01 144 bp overlap
MAFF 2 datasets
Motif DE_60h DE_60h-MAFF_MA0495.4 11 bp overlap
Motif DE_72h DE_72h-MAFF_MA0495.4 11 bp overlap
MGA 1 dataset
Motif DE_48h DE_48h-MGA_MA0801.1 8 bp overlap
MTA2 1 dataset
ChIP RH4 GSE155861.MTA2.RH4 491 bp overlap
MYB 1 dataset
Motif DE_48h DE_48h-MYB_MA0100.4 6 bp overlap
MYOG 1 dataset
ChIP RH4_Entinostat-6H GSE116344.MYOG.RH4_Entinostat-6H 181 bp overlap
MZF1 1 dataset
ChIP HEK293 ENCSR298QUH.MZF1.HEK293 269 bp overlap
Mafb 4 datasets
Motif DE_60h DE_60h-Mafb_MA0117.3 11 bp overlap
Motif DE_60h DE_60h-Mafb_MA0117.3 11 bp overlap
Motif DE_72h DE_72h-Mafb_MA0117.3 11 bp overlap
Motif DE_72h DE_72h-Mafb_MA0117.3 11 bp overlap
NANOG 5 datasets
ChIP HUES-8 GSE109524.NANOG.HUES-8 203 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 210 bp overlap
ChIP WA09 GSE105028.NANOG.WA09 194 bp overlap
ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 193 bp overlap
ChIP hESC GSE18292.NANOG.hESC 93 bp overlap
NFIA 2 datasets
Motif DE_48h DE_48h-NFIA_MA0670.2 6 bp overlap
ChIP K-562 GSE97661.NFIA.K-562 217 bp overlap
NFIB 5 datasets
Motif DE_48h DE_48h-NFIB_MA1643.2 17 bp overlap
ChIP MCF-7 ENCFF799WGQ 308 bp overlap
ChIP MCF-7 ENCFF925CGH 289 bp overlap
ChIP MCF-7 ENCSR582ZOA.NFIB.MCF-7 276 bp overlap
ChIP MCF-7 ENCSR702BYX.NFIB.MCF-7 261 bp overlap
NFIC 5 datasets
Motif DE_48h DE_48h-NFIC_MA1527.2 15 bp overlap
ChIP Ishikawa ENCSR000BUT.NFIC.Ishikawa 188 bp overlap
ChIP K-562 ENCSR796ITY.NFIC.K-562 316 bp overlap
ChIP K562 ENCFF167YID 247 bp overlap
ChIP SK-N-SH ENCSR000BSV.NFIC.SK-N-SH 122 bp overlap
NFIC::TLX1 1 dataset
Motif DE_48h DE_48h-NFICTLX1_MA0119.1 14 bp overlap
NFIX 2 datasets
Motif DE_48h DE_48h-NFIX_MA0671.2 6 bp overlap
Motif DE_48h DE_48h-NFIX_MA1528.2 14 bp overlap
NFKB1 1 dataset
Motif DE_60h DE_60h-NFKB1_MA0105.4 13 bp overlap
NFKB2 1 dataset
Motif DE_60h DE_60h-NFKB2_MA0778.2 11 bp overlap
NFYA 1 dataset
Motif DE_48h DE_48h-NFYA_MA0060.4 8 bp overlap
NFYB 1 dataset
Motif DE_48h DE_48h-NFYB_MA0502.3 9 bp overlap
NFYC 1 dataset
Motif DE_48h DE_48h-NFYC_MA1644.2 7 bp overlap
NR1D1 1 dataset
Motif DE_48h DE_48h-NR1D1_MA1531.2 14 bp overlap
NR1I3 2 datasets
Motif DE_60h DE_60h-NR1I3_MA1534.2 8 bp overlap
Motif DE_72h DE_72h-NR1I3_MA1534.2 8 bp overlap
NR2C1 2 datasets
Motif DE_60h DE_60h-NR2C1_MA1535.2 6 bp overlap
Motif DE_72h DE_72h-NR2C1_MA1535.2 6 bp overlap
NR2C2 2 datasets
Motif DE_60h DE_60h-NR2C2_MA1536.2 6 bp overlap
Motif DE_72h DE_72h-NR2C2_MA1536.2 6 bp overlap
NR2F2 2 datasets
Motif DE_60h DE_60h-NR2F2_MA1111.2 7 bp overlap
Motif DE_72h DE_72h-NR2F2_MA1111.2 7 bp overlap
NR4A2 2 datasets
Motif DE_60h DE_60h-NR4A2_MA0160.3 8 bp overlap
Motif DE_72h DE_72h-NR4A2_MA0160.3 8 bp overlap
Nr1H2 2 datasets
Motif DE_60h DE_60h-Nr1H2_MA1996.2 6 bp overlap
Motif DE_72h DE_72h-Nr1H2_MA1996.2 6 bp overlap
Nr1H4 2 datasets
Motif DE_60h DE_60h-Nr1H4_MA1110.3 6 bp overlap
Motif DE_72h DE_72h-Nr1H4_MA1110.3 6 bp overlap
Nr1h3 2 datasets
Motif DE_60h DE_60h-Nr1h3_MA2337.1 6 bp overlap
Motif DE_72h DE_72h-Nr1h3_MA2337.1 6 bp overlap
Nr2F6 1 dataset
Motif DE_48h DE_48h-Nr2F6_MA0728.1 15 bp overlap
POU2F2 2 datasets
Motif DE_60h DE_60h-POU2F2_MA0507.3 13 bp overlap
Motif DE_72h DE_72h-POU2F2_MA0507.3 13 bp overlap
POU3F3 2 datasets
Motif DE_60h DE_60h-POU3F3_MA0788.1 13 bp overlap
Motif DE_72h DE_72h-POU3F3_MA0788.1 13 bp overlap
POU5F1 5 datasets
ChIP HUES-8 GSE109524.POU5F1.HUES-8 280 bp overlap
ChIP WA09_heat-shock GSE105028.POU5F1.WA09_heat-shock 187 bp overlap
ChIP hESC ENCSR264RJX.POU5F1.hESC 143 bp overlap
ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 222 bp overlap
ChIP hiPSC GSE56567.POU5F1.hiPSC 178 bp overlap
POU6F1 2 datasets
Motif DE_60h DE_60h-POU6F1_MA1549.2 7 bp overlap
Motif DE_72h DE_72h-POU6F1_MA1549.2 7 bp overlap
PPARG 2 datasets
Motif DE_60h DE_60h-PPARG_MA0066.2 19 bp overlap
Motif DE_72h DE_72h-PPARG_MA0066.2 19 bp overlap
PRDM9 2 datasets
Motif DE_48h DE_48h-PRDM9_MA1723.2 20 bp overlap
Motif DE_48h DE_48h-PRDM9_MA1723.2 20 bp overlap
Ppara 2 datasets
Motif DE_60h DE_60h-Ppara_MA2338.1 7 bp overlap
Motif DE_72h DE_72h-Ppara_MA2338.1 7 bp overlap
Pparg::Rxra 1 dataset
Motif DE_48h DE_48h-PpargRxra_MA0065.3 13 bp overlap
RARA 1 dataset
Motif DE_48h DE_48h-RARA_MA0729.1 18 bp overlap
RBPJ 2 datasets
Motif DE_48h DE_48h-RBPJ_MA1116.2 6 bp overlap
Motif DE_60h DE_60h-RBPJ_MA1116.2 6 bp overlap
REST 1 dataset
Motif DE_60h DE_60h-REST_MA0138.3 20 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 448 bp overlap
SMAD2_3 1 dataset
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 292 bp overlap
SMARCA4 3 datasets
ChIP 501-mel_SHCTR GSE61965.SMARCA4.501-mel_SHCTR 204 bp overlap
ChIP TTC-549_Dox GSE71504.SMARCA4.TTC-549_Dox 202 bp overlap
ChIP hiPSC GSE124903.SMARCA4.hiPSC 468 bp overlap
SMARCB1 1 dataset
ChIP hiPSC GSE124903.SMARCB1.hiPSC 390 bp overlap
SMARCC1 3 datasets
ChIP TTC-549_Dox GSE71504.SMARCC1.TTC-549_Dox 267 bp overlap
ChIP hiPSC GSE124903.SMARCC1.hiPSC 256 bp overlap
ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 218 bp overlap
SOX13 1 dataset
Motif DE_60h DE_60h-SOX13_MA1120.2 7 bp overlap
SOX14 1 dataset
Motif DE_60h DE_60h-SOX14_MA1562.2 9 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 442 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 593 bp overlap
SOX2 3 datasets
Motif DE_60h DE_60h-SOX2_MA0143.5 7 bp overlap
ChIP HNSC GSE69479.SOX2.HNSC 235 bp overlap
ChIP hiPSC GSE56567.SOX2.hiPSC 143 bp overlap
SOX4 1 dataset
Motif DE_60h DE_60h-SOX4_MA0867.3 8 bp overlap
SOX8 2 datasets
Motif DE_60h DE_60h-SOX8_MA0868.3 7 bp overlap
ChIP RH4 GSE116344.SOX8.RH4 210 bp overlap
SOX9 1 dataset
Motif DE_60h DE_60h-SOX9_MA0077.2 8 bp overlap
STAT1::STAT2 1 dataset
Motif DE_72h DE_72h-STAT1STAT2_MA0517.2 13 bp overlap
Sox11 1 dataset
Motif DE_60h DE_60h-Sox11_MA0869.3 8 bp overlap
Sox17 1 dataset
Motif DE_60h DE_60h-Sox17_MA0078.3 10 bp overlap
Sox3 1 dataset
Motif DE_60h DE_60h-Sox3_MA0514.3 7 bp overlap
Sox5 1 dataset
Motif DE_60h DE_60h-Sox5_MA0087.3 8 bp overlap
Sox6 1 dataset
Motif DE_60h DE_60h-Sox6_MA0515.1 10 bp overlap
Sox7 1 dataset
Motif DE_60h DE_60h-Sox7_MA2095.1 10 bp overlap
Spz1 2 datasets
Motif DE_60h DE_60h-Spz1_MA0111.1 11 bp overlap
Motif DE_72h DE_72h-Spz1_MA0111.1 11 bp overlap
TBX1 1 dataset
Motif DE_48h DE_48h-TBX1_MA0805.1 8 bp overlap
TBX15 1 dataset
Motif DE_48h DE_48h-TBX15_MA0803.1 8 bp overlap
TBX20 1 dataset
Motif DE_48h DE_48h-TBX20_MA0689.1 11 bp overlap
TBX21 1 dataset
Motif DE_48h DE_48h-TBX21_MA0690.3 10 bp overlap
TBX5 1 dataset
Motif DE_48h DE_48h-TBX5_MA0807.1 8 bp overlap
ZKSCAN3 1 dataset
Motif DE_60h DE_60h-ZKSCAN3_MA1973.2 14 bp overlap
ZNF184 1 dataset
Motif DE_48h DE_48h-ZNF184_MA2120.1 13 bp overlap
ZNF354A 2 datasets
Motif DE_60h DE_60h-ZNF354A_MA1978.2 20 bp overlap
Motif DE_72h DE_72h-ZNF354A_MA1978.2 20 bp overlap
ZNF460 1 dataset
Motif DE_60h DE_60h-ZNF460_MA1596.1 16 bp overlap
ZNF462 2 datasets
ChIP GM23338 ENCFF896CCA 237 bp overlap
ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 161 bp overlap
ZNF530 1 dataset
Motif DE_48h DE_48h-ZNF530_MA1981.2 14 bp overlap
ZSCAN4 1 dataset
Motif DE_48h DE_48h-ZSCAN4_MA1155.1 15 bp overlap
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